orotic acid has been researched along with Liver Dysfunction in 65 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (96.92) | 18.7374 |
| 1990's | 2 (3.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| REICHARD, P | 1 |
| ANDERSON, EP | 1 |
| AQVIST, SE | 1 |
| STANDERFER, SB | 1 |
| HANDLER, P | 1 |
| BECKMANN, K | 1 |
| BRUGEL, H | 1 |
| MERTZ, DP | 1 |
| SCHWIETZER, C | 2 |
| ALLODI, A | 1 |
| MURATORI, F | 1 |
| DIOGUARDI, N | 1 |
| SECCHI, GC | 1 |
| VALAGUSSA, L | 2 |
| DOTTI, F | 1 |
| BONETTI, G | 1 |
| DE MARTIIS, M | 1 |
| BURGMANN, W | 1 |
| CASADIO, V | 1 |
| CASIROLA, G | 1 |
| VERCILLO, L | 1 |
| PEZZAGNO, G | 1 |
| HATAKEYAMA, T | 1 |
| DEMEULENAERE, L | 1 |
| PASQUARIELLO, G | 1 |
| MEEROFF, M | 2 |
| DEL REGNO, F | 1 |
| ODOARDI, GB | 1 |
| RAMBALDI, M | 1 |
| PINTO, G | 1 |
| MASUYA, T | 1 |
| YOSHIKAWA, T | 1 |
| TANAKA, K | 2 |
| KAWABE, M | 1 |
| HIRAYAMA, C | 1 |
| OHE, K | 1 |
| SUVA, J | 1 |
| LAHN, V | 1 |
| MATEJKA, M | 1 |
| YAMAZAKI, H | 1 |
| SEITZ, K | 1 |
| TSUKADA, K | 1 |
| LIEBERMAN, I | 1 |
| HIATT, HH | 1 |
| LAREAU, J | 1 |
| FAUSTO, N | 2 |
| UCHIYAMA, T | 2 |
| VANLANCKER, JL | 2 |
| CRONE, M | 1 |
| ITZHAKI, S | 1 |
| KIM, S | 1 |
| COHEN, PP | 1 |
| BARCARDINOGUERA, R | 1 |
| TARRUELLA, J | 1 |
| ERILLSAEZ, S | 1 |
| NAGATANI, K | 1 |
| OKABU, M | 1 |
| TOZAWA, T | 1 |
| KURIHARA, R | 1 |
| TAKEDA, S | 1 |
| PETERS, E | 2 |
| Cachin, M | 2 |
| Alagille, D | 1 |
| Hashimoto, S | 2 |
| Steele, RD | 1 |
| Malinovsky, NN | 1 |
| Vinnitsky, LI | 1 |
| Zhidkov, IL | 1 |
| Menninger, U | 1 |
| Menninger, W | 1 |
| Sadanobu, S | 1 |
| Takeuchi, M | 1 |
| Tezuka, M | 1 |
| Porta, EA | 1 |
| Fehér, VJ | 1 |
| Jakab, L | 1 |
| Tenczer, J | 1 |
| Szilvási, I | 1 |
| Hirsch, W | 1 |
| Smerlings, H | 1 |
| Blasy, J | 1 |
| Bayazid, A | 1 |
| Gerhard, W | 1 |
| Higueret, P | 1 |
| Chany, E | 1 |
| Mousset, S | 1 |
| Gardes, M | 1 |
| Frayssinet, C | 1 |
| Wegener, W | 1 |
| Stuchlik, S | 1 |
| Tàmmaro, AE | 1 |
| Bonaccorso, O | 1 |
| Manjeshwar, S | 1 |
| Rao, PM | 1 |
| Rajalakshmi, S | 1 |
| Sarma, DS | 1 |
| Visek, WJ | 1 |
| Wallnöfer, H | 1 |
| Lechat, S | 1 |
| Pattin, S | 1 |
| Vigne, J | 1 |
| Petzold, H | 1 |
| Neupert, A | 1 |
| Monges, H | 1 |
| Salducci, J | 1 |
| Chlumský, J | 1 |
| Hyncík, V | 1 |
| Négret, JP | 1 |
| Fujisawa, K | 1 |
| Okabe, K | 1 |
| Pergola, F | 1 |
| Bogenhard, H | 1 |
| Kobayashi, T | 1 |
| Girard, MM | 1 |
1 review available for orotic acid and Liver Dysfunction
| Article | Year |
|---|---|
Nutrition and diseases of the liver and gallbladder.
Topics: Alcoholism; Animals; Atrophy; Avitaminosis; Fatty Acids, Essential; Fatty Liver; Gallbladder Disease | 1975 |
5 trials available for orotic acid and Liver Dysfunction
| Article | Year |
|---|---|
[Drug therapy of liver diseases with Hepatofalk].
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Cysteine; Drug Combinations; Female; Folic Acid; | 1976 |
[Repair, regeneration and metabolism of liver cells: a clinical report].
Topics: Choline; Clinical Trials as Topic; Dehydrocholic Acid; Drug Combinations; Drug Evaluation; Gallbladd | 1979 |
[Clinical experience with the oral liver-therapeutic agent Hepavis].
Topics: Adult; Aged; Choline; Clinical Trials as Topic; Dehydrocholic Acid; Drug Combinations; Drug Evaluati | 1976 |
[A.I.C.A. orotate in hepatic pathology].
Topics: Clinical Trials as Topic; Drug Tolerance; Humans; Imidazoles; Liver Diseases; Orotic Acid | 1969 |
[On the diagnosis and therapy of chronic hepatopathies. Experiences with Orgatract].
Topics: Clinical Trials as Topic; Cysteine; Humans; Liver Diseases; Liver Extracts; Orotic Acid; Pyridoxine | 1965 |
59 other studies available for orotic acid and Liver Dysfunction
| Article | Year |
|---|---|
The function of orotic acid in the biogenesis of pyrimidines in slices from regenerating liver.
Topics: Humans; Hyperplasia; Liver; Liver Diseases; Liver Regeneration; Orotic Acid; Pyrimidines | 1952 |
A double precursor study of nucleic acid turnover in normal and regenerating liver.
Topics: Liver; Liver Diseases; Liver Regeneration; Nucleic Acids; Orotic Acid; Phosphates | 1953 |
Fatty liver induced by orotic acid feeding.
Topics: Fatty Liver; Liver Diseases; Orotic Acid | 1955 |
[Treatment of diseases of liver parenchyma; experiences with intravenous injections of a preparation containing a mixture of orotic acid and purines].
Topics: Adenine; Humans; Injections, Intravenous; Liver Diseases; Orotic Acid; Purines; Xanthines | 1956 |
[Physiological properties of orotic acid].
Topics: Biological Phenomena; Fertility; Fertility Agents; Growth; Liver Diseases; Orotic Acid; Physiologica | 1956 |
[Physiological properties of orotic acid].
Topics: Biological Phenomena; Fertility; Fertility Agents; Growth; Liver Diseases; Orotic Acid; Physiologica | 1956 |
[Physiological properties of orotic acid].
Topics: Biological Phenomena; Fertility; Fertility Agents; Growth; Liver Diseases; Orotic Acid; Physiologica | 1956 |
[Physiological properties of orotic acid].
Topics: Biological Phenomena; Fertility; Fertility Agents; Growth; Liver Diseases; Orotic Acid; Physiologica | 1956 |
[Effects of a new preparation of purinic and orotic acid base in chronic liver diseases].
Topics: Adenine; Alkalies; Humans; Liver Diseases; Organic Chemicals; Orotic Acid; Xanthines | 1957 |
[Findings on the effect of orotic acid on protein metabolism; initial data on its use in combination with alpha-tocopherol in cases of chronic liver diseases].
Topics: alpha-Tocopherol; Blood Proteins; Enzymes; Humans; Liver Cirrhosis; Liver Diseases; Orotic Acid; Pro | 1957 |
[Behavior of blood ketones in chronic decompensated liver diseases during treatment with potassium orotate & alpha-tocopherol].
Topics: alpha-Tocopherol; Humans; Keto Acids; Ketones; Liver Cirrhosis; Liver Diseases; Orotic Acid; Vitamin | 1957 |
[First experience with potassium orotate therapy of chronic liver diseases].
Topics: Humans; Liver Diseases; Nucleotides; Nutrition Therapy; Organic Chemicals; Orotic Acid | 1958 |
[Orotic acid].
Topics: Humans; Liver Diseases; Orotic Acid | 1959 |
[Adjustment of the body fluid balance in chronic liver diseases with orotic acid & purines (purinor)].
Topics: Body Fluids; Diuretics; Liver Diseases; Orotic Acid; Purines; Water-Electrolyte Balance | 1959 |
[On the therapeutic use of a new orotic acid salt (choline orotate)].
Topics: Anemia; Choline; Humans; Liver Diseases; Orotic Acid; Sodium Chloride; Sodium Chloride, Dietary | 1960 |
[Influence of potassium orotate on hydrosaline metabolism in patients of liver disease].
Topics: Humans; Liver Diseases; Metabolic Diseases; Orotic Acid; Potassium; Water-Electrolyte Balance | 1961 |
[Studies on nutrition and hepatic injury. 4. Studies on experimental fatty liver; effects of addition of lipoic acid, orotic acid, lvsine, threonine, and fermented sovbeans].
Topics: Fatty Liver; Glycine max; Liver Diseases; Lysine; Nutritional Status; Orotic Acid; Thioctic Acid; Th | 1961 |
[Clinical study of the treatment of certain liver diseases with the potassium salt of orotic acid].
Topics: Hepatitis; Hepatitis A; Humans; Liver Cirrhosis; Liver Diseases; Orotic Acid; Potassium | 1961 |
[Orotic acid in hepatology].
Topics: Gastroenterology; Liver Diseases; Organic Chemicals; Orotic Acid | 1960 |
[Orotic acid in chronic hepatic diseases].
Topics: Chronic Disease; Liver Diseases; Organic Chemicals; Orotic Acid | 1961 |
[Clinicometabolic observations in patients with liver diseases treated with orotic acid].
Topics: Liver Diseases; Organic Chemicals; Orotic Acid | 1959 |
[Behavior of bloodketones in chronic decompensated liver diseases, in the course of treatment with potassium orotate and alpha-tocopherol].
Topics: alpha-Tocopherol; Humans; Liver Diseases; Orotic Acid; Vascular Diseases; Vitamin E | 1961 |
[Mechanism of liver fibrosis, and counter-measures].
Topics: Adrenal Cortex Hormones; Chondroitin; Glucuronates; Hexosamines; Humans; Imidazoles; Liver Cirrhosis | 1963 |
[Orotic acid in the treatment of acute and chronic liver diseases].
Topics: Liver Diseases; Orotic Acid | 1962 |
Lipid metabolism in hepatic injury. 3. Effect of orotic acid on serum and liver lipid levels in rats with subacute hepatic injury induced by the repeated injections of carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Lipid Metabolism; Lipids; Liver Disea | 1962 |
[Effect of orotic acid on liver lesions and its relation to enzymatic activity].
Topics: Gastrointestinal Diseases; Liver Diseases; Orotic Acid; Transaminases | 1961 |
[PHARMACOLOGY OF SUBSTANCES OF THE NUCLEIC ACID SERIES].
Topics: Adenosine Triphosphate; DNA; Imidazoles; Liver Diseases; Nucleic Acids; Nucleosides; Orotic Acid; Ph | 1963 |
[ON THE INFLUENCE OF CARDIAC INSUFFICIENCY ON THE LIVER--THERAPEUTIC CONSEQUENCES].
Topics: Heart Failure; Humans; Hypoxia; Liver Diseases; Liver Function Tests; Orotic Acid | 1963 |
METABOLISM OF NUCLEOLAR RIBONUCLEIC ACID AFTER PARTIAL HEPATECTOMY.
Topics: Amides; Carbon Isotopes; Cell Nucleus; Dactinomycin; Hepatectomy; Liver; Liver Diseases; Liver Regen | 1964 |
THE SYNTHESIS AND DEGRADATION OF LIVER RIBONUCLEIC ACID.
Topics: Carbon Isotopes; Cell Nucleus; Hepatectomy; Liver; Liver Diseases; Liver Extracts; Liver Regeneratio | 1963 |
METABOLIC ALTERATIONS AFTER TOTAL BODY DOSES OF X-RADIATION. EFFECT OF IRRADIATION OF NORMAL LIVER ON DNA SYNTHESIS AFTER PARTIAL HEPATECTOMY.
Topics: Carbon Isotopes; DNA; Hepatectomy; Liver Diseases; Liver Regeneration; Metabolism; Nucleotidyltransf | 1964 |
ON THE RELATIVE FUNCTIONING OF THE PATHWAYS FOR FORMATION OF THYMIDINE NUCLEOTIDES IN THE REGNERATING LIVER AND SPLEEN OF THE RAT.
Topics: Carbon Isotopes; DNA; Liver Diseases; Liver Regeneration; Metabolism; Nucleosides; Nucleotides; Orot | 1965 |
TRANSCARBAMYLASE ACTIVITY IN FETAL LIVER AND IN LIVER OF PARTIALLY HEPATECTOMIZED PARABIOTIC RATS.
Topics: Cell Division; Enzyme Precursors; Erythrocyte Count; Fetus; Guinea Pigs; Hepatectomy; Ligases; Liver | 1965 |
METABOLIC ALTERATIONS AFTER TOTAL-BODY DOSES OF X-IRRADIATION. THE EFFECTS OF X-IRRADIATION ON RAPIDLY LABELED RNA.
Topics: DNA; Hepatectomy; Liver Diseases; Liver Regeneration; Metabolism; Nucleotidyltransferases; Orotic Ac | 1965 |
[EFFICACY OF NITROGENOUS BASES IN THE TREATMENT OF DIFFUSE HEPATIC DISEASES].
Topics: Alkalies; Drug Therapy; Humans; Liver Diseases; Nitrogen; Orotic Acid; Purines | 1965 |
Fatty liver induction by orotic acid.
Topics: Fatty Liver; Humans; Liver Diseases; Orotic Acid | 1960 |
[Therapeutic results of orotic acid in liver diseases].
Topics: Liver Diseases; Organic Chemicals; Orotic Acid | 1962 |
[On the therapy of liver damage with orotic acid].
Topics: Liver Diseases; Orotic Acid | 1962 |
[On the therapy of liver diseases with orotic acid].
Topics: Liver Diseases; Orotic Acid | 1962 |
[Treatment of hepato-biliary diseases in children and adults by a drug composed of orotic acid and sorbitol].
Topics: Adult; Biliary Tract Diseases; Child; Female; Gastrointestinal Diseases; Humans; Infant; Liver Disea | 1967 |
Effects of nucleic acid precursors on liver injuries. I. Treatment of liver injury induced by low protein, amino acid imbalanced diet with AICA and AICA orotate in massive doses.
Topics: Amino Acids; Animals; Caseins; Liver Diseases; Nucleic Acids; Orotic Acid; Protein Deficiency; Rats | 1967 |
Effects of nucleic acid precursors on liver injuries. II. The influences of AICA and AICA orotate on metabolisms in liver injuries and their clinical significances.
Topics: Animals; Humans; Liver Diseases; Male; Nucleic Acids; Orotic Acid; Protein Deficiency; Rats | 1967 |
Hyperammonemia and orotic aciduria in portacaval-shunted rats.
Topics: Ammonia; Ammonium Chloride; Animals; Arginine; Benzoates; Benzoic Acid; Liver; Liver Diseases; Male; | 1984 |
Assessment of hepatic tissue blood flow with 133Xe clearance technique.
Topics: Animals; Dogs; Liver; Liver Diseases; Male; Microcirculation; Orotic Acid; Rats; Uracil; Xenon Radio | 1981 |
[Clinical experience report on Hepavis].
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Choline; Dehydrocholic Acid; Drug Co | 1980 |
Effect of 1,3-dithia-2-thioxo-cyclopent-4-ene and its derivatives on liver injury induced by carbon tetrachloride and orotic acid in rats.
Topics: Administration, Oral; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1997 |
[Clinical studies on the liver-protective effect of 4-amino-5-imidazole carboxamide and orotic acid].
Topics: Aminoimidazole Carboxamide; Aspartate Aminotransferases; Drug Therapy, Combination; gamma-Globulins; | 1977 |
[Inhibiting effects of protein fractions isolated from the rat liver in compensating hypertrophy after partial hepatectomy].
Topics: Animals; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Gel; DNA; Feedback; Hep | 1975 |
[Reflections on medicamentous liver-therapy. Hepavis in medical practice].
Topics: Adult; Choline; Dehydrocholic Acid; Drug Combinations; Female; Humans; Liver Diseases; Magnesium; Ma | 1977 |
[Treatment with Hepavis, a new cholerectically-active hepaticum. Experiences from an internal medicine profemoral practice].
Topics: Adult; Cholagogues and Choleretics; Choline; Dehydrocholic Acid; Drug Combinations; Drug Evaluation; | 1977 |
[Current views on the liver-protective therapy: clinical evaluation of 4-amino-5-carbamide imidazole 2,4-dihydroxy-6-pyrimidine carbonate].
Topics: Aged; Drug Combinations; Female; Humans; Imidazoles; Liver; Liver Diseases; Liver Extracts; Male; Mi | 1975 |
Inhibition of DNA synthesis by phenobarbital in primary cultures of hepatocytes from normal rat liver and from hepatic nodules.
Topics: Animals; Carcinogens; Cells, Cultured; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Liv | 1992 |
Arginine and disease states.
Topics: Ammonia; Animals; Arginine; Blood Glucose; Humans; Insulin; Lipid Metabolism; Liver Diseases; Male; | 1985 |
[The treatment of hepatoses].
Topics: Biotransformation; Chemical and Drug Induced Liver Injury; Cholestasis; Diet Therapy; Fatty Liver; G | 1972 |
[Value of an orotic acid-sorbitol combination in hepato-intestinal diseases. Point of view of a general practitioner].
Topics: Adult; Aged; Alcoholism; Dyspepsia; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Male | 1967 |
[Enzyme histochemical findings in the rat liver following galactosamine lesions and cholinorotate].
Topics: Acid Phosphatase; Adenosine Triphosphatases; Alkaline Phosphatase; Animals; Chemical and Drug Induce | 1972 |
[Problem of active therapeutic procedure in chronic liver disease].
Topics: Adenine; Adult; Aged; Chronic Disease; Diet Therapy; Female; Humans; Inositol; Liver Diseases; Male; | 1972 |
[Clinical experimentation with Aïcamine in hepatic insufficiency].
Topics: Adolescent; Adult; Aged; Carboxylic Acids; Fatty Liver; Female; Hepatitis; Humans; Imidazoles; Liver | 1972 |
[Acute hepatic disorders].
Topics: Acute Disease; Alcoholism; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver | 1972 |
[Aicamine in hepatic pathology].
Topics: Animals; Carboxylic Acids; Humans; Imidazoles; Liver; Liver Diseases; Orotic Acid; Rats | 1971 |
[Pharmacological studies on liver-acting agents 2. Effects of so-called liver drugs on the ethionine-damaged liver].
Topics: Animals; Bile Acids and Salts; Blood Proteins; Chemical and Drug Induced Liver Injury; Ethionine; Gl | 1966 |
[Therapeutic testing of a mixture of orotic acid and sorbitol in adults with hepato-biliary diseases].
Topics: Adult; Gallbladder Diseases; Humans; Liver Diseases; Orotic Acid; Sorbitol | 1967 |