orotic acid has been researched along with Leucocythaemia in 12 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (83.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HANDSCHUMACHER, RE | 2 |
| WEISSMAN, S | 1 |
| EISEN, AZ | 1 |
| KARON, M | 2 |
| LEWIS, M | 1 |
| WEISSMAN, SM | 1 |
| BUTTOO, AS | 1 |
| ISRAUELS, MC | 1 |
| WILKINSON, JF | 1 |
| SATO, K | 1 |
| LEPAGE, GA | 1 |
| Cleaveland, ES | 1 |
| Zaharevitz, DW | 1 |
| Kelley, JA | 1 |
| Paull, K | 1 |
| Cooney, DA | 1 |
| Ford, H | 1 |
| Cadman, E | 1 |
| Eiferman, F | 1 |
| Heimer, R | 1 |
| Davis, L | 1 |
| Reyes, P | 1 |
| Brooke, J | 1 |
| Szabados, E | 1 |
| Lyons, SD | 1 |
| Goodridge, RJ | 1 |
| Harsanyi, MC | 1 |
| Poiner, A | 1 |
| Christopherson, RI | 1 |
| Castoldi, GL | 1 |
| Yam, LT | 1 |
| Mitus, WJ | 1 |
| Vogler, WR | 1 |
| Bain, JA | 1 |
| Huguley, CM | 1 |
12 other studies available for orotic acid and Leucocythaemia
| Article | Year |
|---|---|
5-azaorotic acid and related inhibitors of the synthesis de novo of pyrimidine nucleotides.
Topics: Antimetabolites; Leukemia; Leukemia, Experimental; Liver; Orotic Acid; Pyrimidine Nucleotides; Uraci | 1963 |
Pseudouridine metabolism. II. Urinary excretion in gout, psoriasis, leukemia, and heterozygous oroticaciduria.
Topics: Gout; Humans; Leukemia; Nucleosides; Nucleotides; Orotate Phosphoribosyltransferase; Orotic Acid; Or | 1962 |
STUDIES ON THE PSEUDOURIDINIURIA OF CHRONIC LYMPHOCYTIC LEUKEMIA.
Topics: Body Fluids; Carbon Isotopes; Fluids and Secretions; Humans; Leukemia; Leukemia, Lymphocytic, Chroni | 1964 |
HYPOCHOLESTEROLAEMIA AND OROTIC ACIDURIA DURING TREATMENT WITH 6-AZAURIDINE.
Topics: Antineoplastic Agents; Azauridine; Cholesterol; Drug Therapy; Leukemia; Leukocyte Count; Lymphoma; L | 1965 |
OXONATE AND OTHER RELATED ANTIMETABOLITES OF THE SYNTHESIS DE NOVO OF PYRIMIDINE NUCLEOTIDES.
Topics: Antimetabolites; Autoradiography; Leukemia; Leukemia, Experimental; Liver; Liver Extracts; Metabolis | 1964 |
METABOLIC EFFECTS OF AN ANTIBIOTIC, NSC-51954, ON SUSCEPTIBLE AND RESISTANT TUMOR CELLS.
Topics: Adenine; Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA; DNA, Neopla | 1965 |
Identification of a novel inhibitor (NSC 665564) of dihydroorotate dehydrogenase with a potency equivalent to brequinar.
Topics: Antineoplastic Agents; Aspartic Acid; Biphenyl Compounds; Breast Neoplasms; Carbolines; Carcinoma, N | 1996 |
Pyrazofurin enhancement of 5-azacytidine antitumor activity in L5178Y and human leukemia cells.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Azacitidine; Cell Survival; Drug Synergism; Drug Thera | 1978 |
The rapid separation of orotate, orotidylate, and uridylate by thin-layer chromatography. Utility in the assay of orotate phosphoribosyltransferase and orotidylate decarboxylase.
Topics: Chromatography, Thin Layer; Leukemia; Liver; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidi | 1977 |
Cytotoxic effects of dihydroorotase inhibitors upon human CCRF-CEM leukemia.
Topics: Animals; Cell Cycle; Cell Division; Cell Line; Cell Survival; Dihydroorotase; DNA, Neoplasm; Humans; | 1990 |
Cytochemical demonstration of dihydroorotic dehydrogenase in blood and bone marrow cells.
Topics: Anemia, Aplastic; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cytoplasmic Gra | 1968 |
In vivo effect of hydroxyurea on orotic acid synthesis.
Topics: Adult; Aged; Antimetabolites; DNA; Humans; Leukemia; Melanoma; Middle Aged; Nucleosides; Orotic Acid | 1966 |