orotic acid has been researched along with Insulin Resistance in 2 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether fatty liver preceded insulin resistance or vice versa using a long-term orotic acid (OA)-induced nonalcoholic fatty liver disease (NAFLD) model without the confounding effects of obesity and hyperlipidemia and explored the role of the liver in insulin resistance." | 7.83 | Long-term fatty liver-induced insulin resistance in orotic acid-induced nonalcoholic fatty liver rats. ( Gao, X; Han, X; Liu, C; Wang, J; Wang, Y; Xue, C; Xue, Y; Yanagita, T, 2016) |
| "We investigated whether fatty liver preceded insulin resistance or vice versa using a long-term orotic acid (OA)-induced nonalcoholic fatty liver disease (NAFLD) model without the confounding effects of obesity and hyperlipidemia and explored the role of the liver in insulin resistance." | 3.83 | Long-term fatty liver-induced insulin resistance in orotic acid-induced nonalcoholic fatty liver rats. ( Gao, X; Han, X; Liu, C; Wang, J; Wang, Y; Xue, C; Xue, Y; Yanagita, T, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hong, ES | 1 |
| Kim, EK | 1 |
| Kang, SM | 1 |
| Khang, AR | 1 |
| Choi, SH | 1 |
| Park, KS | 1 |
| Jang, HC | 1 |
| Lim, S | 1 |
| Han, X | 1 |
| Liu, C | 1 |
| Xue, Y | 1 |
| Wang, J | 1 |
| Xue, C | 1 |
| Yanagita, T | 1 |
| Gao, X | 1 |
| Wang, Y | 1 |
1 trial available for orotic acid and Insulin Resistance
| Article | Year |
|---|---|
Effect of carnitine-orotate complex on glucose metabolism and fatty liver: a double-blind, placebo-controlled study.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Blood Glucose; Carnitine; DNA | 2014 |
1 other study available for orotic acid and Insulin Resistance
| Article | Year |
|---|---|
Long-term fatty liver-induced insulin resistance in orotic acid-induced nonalcoholic fatty liver rats.
Topics: Animals; Gene Expression; Gluconeogenesis; Glucose Tolerance Test; Insulin; Insulin Resistance; Male | 2016 |