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orotic acid and Hypertrophy

orotic acid has been researched along with Hypertrophy in 18 studies

Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"Using [5-3H]orotic acid and [5-3H]uridine as precursors, we compared the efficiency of labeling and the localization of labeled RNA during compensatory hypertrophy of the mouse kidney."7.65Differential labeling with orotic acid and uridine in compensatroy renal hypertrophy. ( Caulfield, JA; Malamud, D; Malt, RA; Ross, JS, 1975)
"Renal hypertrophy was prevented in the rats of Group 4."5.29Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet. ( Klahr, S; Reyes, AA, 1994)
" To determine the cell type(s) responsible for the increased RNA synthesis, we compared light autoradiographs of control and hypertrophying muscles from rats injected with tritiated uridine 12, 24, and 48 h after inducing hypertrophy."3.65Autoradiographic localization of new RNA synthesis in hypertrophying skeletal muscle. ( Heuser, JE; Jablecki, CK; Kaufman, S, 1973)
"Renal hypertrophy was prevented in the rats of Group 4."1.29Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet. ( Klahr, S; Reyes, AA, 1994)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199017 (94.44)18.7374
1990's1 (5.56)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DECLOITRE, F1
LOWY, R1
DELHUMEAUDEONGAY, G1
MOULE, Y1
FRAYSSINET, C3
MEERSON, FZ1
Bilich, GL2
Nazarova, LV2
Sungurova, EV1
Reyes, AA1
Klahr, S1
Otmakhov, VN1
Higueret, P1
Chany, E1
Mousset, S1
Gardes, M1
Ross, JS1
Malamud, D1
Caulfield, JA1
Malt, RA1
Riede, UN1
Berli, T1
Mihatsch, M1
Simonson, E1
Berman, R1
Kolos, G1
Williams, JF1
Hickie, JB1
Raick, AN1
Jablecki, CK1
Heuser, JE1
Kaufman, S2
Goldberg, AL1
Paulson, DF1
Fraley, EE1
Sobel, BE1
Munsch, N1
Manchester, KL1
Harris, EJ1

Reviews

2 reviews available for orotic acid and Hypertrophy

ArticleYear
New approach in treatment of cardiac decompensation in U.S.S.R.
    American heart journal, 1973, Volume: 86, Issue:1

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acids; Aortic Valve Stenosis; Cardiac Glyco

1973
Mechanisms of growth and atrophy of skeletal muscle.
    Muscle biology, 1972, Volume: 1

    Topics: Amino Acids; Animals; Atrophy; Cell Division; Food Deprivation; Growth Hormone; Hypertrophy; In Vitr

1972

Other Studies

16 other studies available for orotic acid and Hypertrophy

ArticleYear
[EFFECT OF OROTIC ACID ON THE PROCESSES OF NECROSIS AND TISSUE REPAIR IN THE RAT].
    Enzymologia biologica et clinica, 1964, Volume: 74

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Chemical and Drug Induced Liver Injury; Colorimetry; DN

1964
[EVOLUTION OF MICROSMAL STRUCTURES DURING COMPENSATORY HYPERTROPHY OF RAT LIVER].
    Experimental cell research, 1965, Volume: 38

    Topics: Animals; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Endoplasmic Reticulum; Hepatectomy; H

1965
A MECHANISM OF HYPERTROPHY AND WEAR OF THE MYOCARDIUM.
    The American journal of cardiology, 1965, Volume: 15

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Aortic Valve Stenosis; Cardiomegaly; Car

1965
The enzymatic status of circulating lymphocytes as an index of the regenerative process in the lungs under stimulation with pyrimidine and purine derivatives. A clinical experimental study.
    Haematologia, 1982, Volume: 15, Issue:1

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Glycerolphosphate Dehydrogenase; Humans; Hypertroph

1982
Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1994, Volume: 206, Issue:2

    Topics: Animals; Arginine; Body Weight; Creatinine; Dietary Proteins; Female; Hypertrophy; Kidney; Organ Siz

1994
[Effect of orotic acid on reparative processes in the lungs following pneumonectomy].
    Arkhiv anatomii, gistologii i embriologii, 1979, Volume: 76, Issue:6

    Topics: Animals; DNA; Hypertrophy; Lung; Lymphocytes; Mitosis; Orotic Acid; Oxidoreductases; Pneumonectomy;

1979
[Inhibiting effects of protein fractions isolated from the rat liver in compensating hypertrophy after partial hepatectomy].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1975, Jul-07, Volume: 281, Issue:1

    Topics: Animals; Cell Fractionation; Chromatography, DEAE-Cellulose; Chromatography, Gel; DNA; Feedback; Hep

1975
Differential labeling with orotic acid and uridine in compensatroy renal hypertrophy.
    The American journal of physiology, 1975, Volume: 229, Issue:4

    Topics: Animals; DNA; Hypertrophy; Isotope Labeling; Kidney; Kidney Tubules; Male; Mice; Nephrectomy; Orotic

1975
[Influence of exogenously administered orotic acid on enchondral ossification (author's transl)].
    Beitrage zur Pathologie, 1973, Volume: 149, Issue:1

    Topics: Acid Phosphatase; Animal Feed; Animals; Bone Diseases, Developmental; Cartilage; Epiphyses; Histocyt

1973
Biochemical studies in myocardial hypertrophy and metabolic support of the acutely stressed myocardium.
    Advances in cardiology, 1974, Volume: 12, Issue:0

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cardiomegaly; Creatine Kinase; Heart; Hy

1974
Ultrastructural, histological, and biochemical alterations produced by 12-O-tetradecanoyl-phorbol-13-acetate on mouse epidermis and their relevance to skin tumor promotion.
    Cancer research, 1973, Volume: 33, Issue:2

    Topics: Animals; Cell Nucleolus; Cell Transformation, Neoplastic; Croton Oil; Cytoplasm; DNA; Endoplasmic Re

1973
Autoradiographic localization of new RNA synthesis in hypertrophying skeletal muscle.
    The Journal of cell biology, 1973, Volume: 57, Issue:3

    Topics: Animals; Autoradiography; Cell Fractionation; Connective Tissue; Dactinomycin; Fibroblasts; Hypertro

1973
Compensatory renal growth after unilateral ureteral obstruction.
    Kidney international, 1973, Volume: 4, Issue:1

    Topics: Anesthesia, Intravenous; Animals; Carbon Isotopes; DNA; Hyperplasia; Hypertrophy; Kidney; Kidney Dis

1973
Enhanced RNA polymerase activity in skeletal muscle undergoing hypertrophy.
    Archives of biochemistry and biophysics, 1970, Volume: 137, Issue:2

    Topics: Animals; Carbon Isotopes; Cell Nucleus; DNA; Hypertrophy; Magnesium; Microsomes; Muscles; Orotic Aci

1970
[Action of acrolein on the synthesis of nucleic acids in vivo].
    Biochimie, 1971, Volume: 53, Issue:2

    Topics: Aldehydes; Animals; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; DNA; Hepatectomy; Hypertrophy; Li

1971
Effect of denervation on the synthesis of ribonucleic acid and deoxyribonucleic acid in rat diaphragm muscle.
    The Biochemical journal, 1968, Volume: 108, Issue:2

    Topics: Adenine; Animals; Carbon Isotopes; Diaphragm; DNA; DNA Replication; Hypertrophy; Muscle Denervation;

1968