orotic acid has been researched along with Hepatic Encephalopathy in 4 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Relative deficiencies of ornithine or arginine occur in the presence of excessive ammonia, excessive lysine, growth, pregnancy, trauma, or protein deficiency and malnutrition." | 4.77 | Conditional deficiencies of ornithine or arginine. ( Zieve, L, 1986) |
| "A young patient with hepatocellular carcinoma receiving chemotherapy presented with encephalopathy." | 1.35 | Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency. ( Blanke, CD; Chan, JS; Harding, CO, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BARRE, Y | 1 |
| CAROLI, J | 1 |
| MOLLE, J | 1 |
| TREMOLIERES, J | 1 |
| VAN DEN DRIESSCHE, J | 1 |
| VIGNERON, M | 1 |
| Chan, JS | 1 |
| Harding, CO | 1 |
| Blanke, CD | 1 |
| Zieve, L | 1 |
| Benjamin, LE | 1 |
| Steele, RD | 1 |
1 review available for orotic acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
Conditional deficiencies of ornithine or arginine.
Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Arginine; Citrulline; Female; Glycine; H | 1986 |
3 other studies available for orotic acid and Hepatic Encephalopathy
| Article | Year |
|---|---|
[LYSINE OROTATE IN HEPATOLOGY].
Topics: Alcoholism; Chemistry, Pharmaceutical; Drug Therapy; Gastroenterology; Hepatic Encephalopathy; Hepat | 1964 |
Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency.
Topics: Adult; Arginine; Carcinoma, Hepatocellular; Citrulline; Female; Glutamine; Hepatic Encephalopathy; H | 2008 |
The effect of dietary protein on nitrogen and sulfur metabolism in portacaval-shunted rats.
Topics: Amino Acids, Sulfur; Ammonia; Animals; Body Weight; Dietary Proteins; Hepatic Encephalopathy; Liver; | 1986 |