Page last updated: 2024-10-19

orotic acid and Hepatic Encephalopathy

orotic acid has been researched along with Hepatic Encephalopathy in 4 studies

Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research Excerpts

ExcerptRelevanceReference
"Relative deficiencies of ornithine or arginine occur in the presence of excessive ammonia, excessive lysine, growth, pregnancy, trauma, or protein deficiency and malnutrition."4.77Conditional deficiencies of ornithine or arginine. ( Zieve, L, 1986)
"A young patient with hepatocellular carcinoma receiving chemotherapy presented with encephalopathy."1.35Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency. ( Blanke, CD; Chan, JS; Harding, CO, 2008)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BARRE, Y1
CAROLI, J1
MOLLE, J1
TREMOLIERES, J1
VAN DEN DRIESSCHE, J1
VIGNERON, M1
Chan, JS1
Harding, CO1
Blanke, CD1
Zieve, L1
Benjamin, LE1
Steele, RD1

Reviews

1 review available for orotic acid and Hepatic Encephalopathy

ArticleYear
Conditional deficiencies of ornithine or arginine.
    Journal of the American College of Nutrition, 1986, Volume: 5, Issue:2

    Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Arginine; Citrulline; Female; Glycine; H

1986

Other Studies

3 other studies available for orotic acid and Hepatic Encephalopathy

ArticleYear
[LYSINE OROTATE IN HEPATOLOGY].
    La Presse medicale, 1964, Nov-14, Volume: 72

    Topics: Alcoholism; Chemistry, Pharmaceutical; Drug Therapy; Gastroenterology; Hepatic Encephalopathy; Hepat

1964
Postchemotherapy hyperammonemic encephalopathy emulating ornithine transcarbamoylase (OTC) deficiency.
    Southern medical journal, 2008, Volume: 101, Issue:5

    Topics: Adult; Arginine; Carcinoma, Hepatocellular; Citrulline; Female; Glutamine; Hepatic Encephalopathy; H

2008
The effect of dietary protein on nitrogen and sulfur metabolism in portacaval-shunted rats.
    The Journal of nutrition, 1986, Volume: 116, Issue:1

    Topics: Amino Acids, Sulfur; Ammonia; Animals; Body Weight; Dietary Proteins; Hepatic Encephalopathy; Liver;

1986