orotic acid has been researched along with Granulocytic Leukemia, Chronic in 2 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Carboxyamidotriazole-orotate (CTO) is the orotate salt form of carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor that in vitro has been shown to possess antileukaemic activities." | 1.38 | Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis. ( Alessandro, R; Corrado, C; De Leo, G; Flugy, AM; Guggino, G; Karmali, R; Raimondo, S; Taverna, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corrado, C | 1 |
| Flugy, AM | 1 |
| Taverna, S | 1 |
| Raimondo, S | 1 |
| Guggino, G | 1 |
| Karmali, R | 1 |
| De Leo, G | 1 |
| Alessandro, R | 1 |
| Grzelkowska, K | 1 |
| Motyl, T | 1 |
| Ostrowski, J | 1 |
| Trzeciak, L | 1 |
2 other studies available for orotic acid and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Carboxyamidotriazole-orotate inhibits the growth of imatinib-resistant chronic myeloid leukaemia cells and modulates exosomes-stimulated angiogenesis.
Topics: Animals; Antineoplastic Agents; Benzamides; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor | 2012 |
The effect of OA on proliferation and polyamine metabolism of K 562 leukemic cells and their responsiveness to natural killer cell activity.
Topics: Base Sequence; Biogenic Polyamines; Cell Division; Eflornithine; Humans; Killer Cells, Natural; Leuk | 1995 |