orotic acid has been researched along with Folic Acid Deficiency in 5 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, BA | 1 |
| Heimpel, H | 1 |
| Baker, SJ | 1 |
| Smith, LH | 1 |
| Frick, PG | 1 |
2 reviews available for orotic acid and Folic Acid Deficiency
| Article | Year |
|---|---|
Megaloblastic anaemia and disorders affecting utilisation of vitamin B12 and folate in childhood.
Topics: Adolescent; Adult; Anemia, Hemolytic; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Pernicious; | 1976 |
Pyrimidine metabolism in man.
Topics: Amidohydrolases; Aminoisobutyric Acids; Aspartate Carbamoyltransferase; Bacteria; Carboxy-Lyases; Cy | 1973 |
3 other studies available for orotic acid and Folic Acid Deficiency
| Article | Year |
|---|---|
[Dyserythropoiesis and dyserythropoietic anemias].
Topics: Anemia, Aplastic; Erythropoiesis; Folic Acid Deficiency; Humans; Orotic Acid; Vitamin B 12 Deficienc | 1975 |
Nutrition and diseases of the blood: the megaloblastic anaemias.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anemia, Macrocytic; Anemia, Megalo | 1975 |
[Familial forms of megaloblastic anemias].
Topics: Anemia, Macrocytic; Folic Acid Deficiency; Humans; Intellectual Disability; Intestinal Absorption; I | 1970 |