orotic acid has been researched along with Dementia in 5 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nicergoline (NE)--a cerebral vasodilator with nicotinic acid esterified in its molecule--and Antagonic-Stress (AS) composition--a neurometabolic nootropic, also containing nicotinic acid but with fast and prolonged release--were evaluated in senile dementia of Alzheimer's type (SDAT), mild to moderate intensity (DSM-IV Options Book, 1991 and ICD-10, 1990 criteria)." | 5.07 | Superiority of antagonic-stress composition versus nicergoline in gerontopsychiatry. ( Mateescu, R; Măties, R; Mihalas, G; Mihalas, IG; Popa, R; Schneider, F; Stefanigă, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sukyasyan, A | 1 |
| Schneider, F | 1 |
| Popa, R | 1 |
| Mihalas, G | 1 |
| Stefanigă, P | 1 |
| Mihalas, IG | 1 |
| Măties, R | 1 |
| Mateescu, R | 1 |
| Wilde, KM | 1 |
| Hun, N | 1 |
| Villányi, P | 1 |
| Mérei, F | 1 |
| Venter, V | 1 |
| Wenzel, E | 1 |
2 trials available for orotic acid and Dementia
| Article | Year |
|---|---|
Superiority of antagonic-stress composition versus nicergoline in gerontopsychiatry.
Topics: Aged; Aging; Dementia; Double-Blind Method; Drug Combinations; Female; Geriatric Assessment; Humans; | 1994 |
[Clinical studies on the geriatric agent Kavaform. Double blind tests].
Topics: Aged; Anxiety Disorders; Cholesterol; Clinical Trials as Topic; Dementia; Female; Humans; Lipids; Ma | 1967 |
3 other studies available for orotic acid and Dementia
| Article | Year |
|---|---|
The effect of kavaine and magnesium orotate combination in the psycho - organic disorders of the elderly.
Topics: Aged; Dementia; Drug Combinations; Humans; Mental Disorders; Orotic Acid; Pyrans; Pyrones; Silicic A | 1980 |
[Comments on a geriatric drug].
Topics: Aged; Asparagine; Aspartic Acid; Dementia; Drug Combinations; Female; Hematoporphyrins; Humans; Magn | 1974 |
[The therapeutic effect of kavain and magnesium orotate on traumatic and vascular brain lesions].
Topics: Adult; Age Factors; Brain Injuries; Brain Neoplasms; Capsules; Cerebrovascular Disorders; Dementia; | 1971 |