orotic acid has been researched along with Coronary Disease in 11 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A subset of metabolite-HF associations was independent of well-established HF pathways such as increased left ventricular mass index and incident coronary heart disease and included homoarginine (per 1 SD increase in metabolite level, hazard ratio, 0." | 4.02 | Metabolomic Profiles and Heart Failure Risk in Black Adults: Insights From the Jackson Heart Study. ( Andersson, C; Benson, MD; Chen, ZZ; Clish, CB; Correa, A; Cruz, DE; Dailey, L; Gao, Y; Gerszten, RE; Hall, ME; Katz, DH; Ngo, D; Peterson, B; Robbins, JM; Shen, C; Shi, X; Tahir, UA; Vasan, RS; Wang, TJ; Wilson, JG; Zhao, T, 2021) |
| "(6) Magnesium orotate has only a weak inotropic effect, if any, on normal hearts (rats)." | 1.30 | Metabolic supplementation with orotic acid and magnesium orotate. ( Rosenfeldt, FL, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Tahir, UA | 1 |
| Katz, DH | 1 |
| Zhao, T | 1 |
| Ngo, D | 1 |
| Cruz, DE | 1 |
| Robbins, JM | 1 |
| Chen, ZZ | 1 |
| Peterson, B | 1 |
| Benson, MD | 1 |
| Shi, X | 1 |
| Dailey, L | 1 |
| Andersson, C | 1 |
| Vasan, RS | 1 |
| Gao, Y | 1 |
| Shen, C | 1 |
| Correa, A | 1 |
| Hall, ME | 1 |
| Wang, TJ | 1 |
| Clish, CB | 1 |
| Wilson, JG | 1 |
| Gerszten, RE | 1 |
| Gibney, MJ | 1 |
| Burstyn, PG | 1 |
| Rosenfeldt, FL | 1 |
| Geiss, KR | 1 |
| Stergiou, N | 1 |
| Neuenfeld, HU | 1 |
| Jester, HG | 1 |
| Aĭzenberg, AA | 1 |
| Chubikina, VT | 1 |
| Kreminskaia, NK | 1 |
| Brizinskiĭ, MA | 1 |
| Gorbachev, VV | 2 |
| Vecherskiĭ, GA | 2 |
| Baranov, LG | 2 |
| Vedenko, LT | 1 |
| Miasnikov, LA | 1 |
| Metelitsa, VI | 1 |
| Grigor'iants, RA | 1 |
| Krasnikov, IuA | 1 |
| Ignat'ev, MV | 1 |
| Simon, KH | 1 |
1 review available for orotic acid and Coronary Disease
| Article | Year |
|---|---|
Milk, serum cholesterol, and the Maasai. A hypothesis.
Topics: Adult; Animals; Anticholesteremic Agents; Black or African American; Black People; Calcium, Dietary; | 1980 |
2 trials available for orotic acid and Coronary Disease
| Article | Year |
|---|---|
Effects of magnesium orotate on exercise tolerance in patients with coronary heart disease.
Topics: Coronary Disease; Double-Blind Method; Echocardiography; Exercise; Heart Failure; Humans; Myocardial | 1998 |
[Treatment of chronic coronary insufficiency].
Topics: Adult; Aged; Anabolic Agents; Angina Pectoris; Blood Flow Velocity; Blood Pressure; Blood Volume; Ca | 1968 |
8 other studies available for orotic acid and Coronary Disease
| Article | Year |
|---|---|
Metabolomic Profiles and Heart Failure Risk in Black Adults: Insights From the Jackson Heart Study.
Topics: Adult; Aged; Black or African American; Case-Control Studies; Collagen; Coronary Disease; Effect Mod | 2021 |
Metabolic supplementation with orotic acid and magnesium orotate.
Topics: Animals; Coronary Disease; Humans; Myocardium; Orotic Acid | 1998 |
[Effect of drugs of metabolic action on the contractile capacity of the heart].
Topics: Aged; Coronary Disease; Drug Therapy, Combination; Folic Acid; Humans; Middle Aged; Myocardial Contr | 1978 |
[Effect of potassium orotate on the indicators of rheohepatogram in patients with coronary arteriosclerosis].
Topics: Adult; Aged; Arteriosclerosis; Coronary Disease; Female; Follow-Up Studies; Hemodynamics; Hepatic Ar | 1975 |
[Effect of potassium orotate on the contractile function of the myocardium in patients with coronary aterosclerosis].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Coronary Disease; Heart; Heart Function Tests; Humans; Mi | 1975 |
[Use of RNA synthesis cofactors in complex treatment of patients with ischemic heart disease].
Topics: Adult; Aged; Coronary Disease; Female; Folic Acid; Humans; Male; Middle Aged; Orotic Acid; RNA; Stim | 1974 |
[Therapeutic use of potassium orotate].
Topics: Aged; Cholesterol; Coronary Disease; Electrocardiography; Female; Heart; Humans; Male; Middle Aged; | 1969 |
[Causes of the multilayered effect of magnesium orotate in degenerative heart and vascular diseases (vascular sclerosis)].
Topics: Arteriosclerosis; Coronary Disease; Humans; Magnesium; Magnesium Deficiency; Orotic Acid | 1968 |