orotic acid and Coma
orotic acid has been researched along with Coma in 7 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Coma: A profound state of unconsciousness associated with depressed cerebral activity from which the individual cannot be aroused. Coma generally occurs when there is dysfunction or injury involving both cerebral hemispheres or the brain stem RETICULAR FORMATION.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " Crystalluria in a three-month-old male infant with a history of intermittent vomiting since birth and incipient coma led to the discovery of orotic aciduria." | 3.65 | Partial ornithine carbamyl transferase deficiency: an inborn error of the urea cycle presenting as orotic aciduria in a male infant. ( Mackenzie, S; MacLeod, P; Scriver, CR, 1972) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Coskun, T | 1 |
| Ozalp, I | 1 |
| Mönch, S | 1 |
| Kneer, J | 1 |
| Girgis, N | 1 |
| McGravey, V | 1 |
| Shah, BL | 1 |
| Herrin, J | 1 |
| Shih, VE | 1 |
| Rottem, M | 1 |
| Statter, M | 1 |
| Amit, R | 1 |
| Brand, N | 1 |
| Bujanover, Y | 1 |
| Yatziv, S | 1 |
| Rowe, PC | 1 |
| Newman, SL | 1 |
| Brusilow, SW | 1 |
| Batshaw, ML | 1 |
| Sunshine, P | 1 |
| Lindenbaum, JE | 1 |
| Levy, HL | 1 |
| Freeman, JM | 1 |
| MacLeod, P | 1 |
| Mackenzie, S | 1 |
| Scriver, CR | 1 |
Other Studies
7 other studies available for orotic acid and Coma
| Article | Year |
|---|---|
Lethal hyperammonaemic coma due to ornithine transcarbamylase deficiency presenting as brain stem encephalitis in a previously asymptomatic ten-year-old boy.
Topics: Ammonia; Brain Stem; Child; Citrulline; Coma; Diagnosis, Differential; Encephalitis; Humans; Male; O | 1987 |
Lethal ornithine transcarbamylase deficiency in a female neonate.
Topics: Ammonia; Arginine; Citrulline; Coma; Female; Humans; Infant, Newborn; Ornithine Carbamoyltransferase | 1987 |
Clinical and laboratory study in 22 patients with inherited hyperammonemic syndromes.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Child; Coma; Female; Humans; Male; Orotic Acid; Pedig | 1986 |
Natural history of symptomatic partial ornithine transcarbamylase deficiency.
Topics: Amino Acid Metabolism, Inborn Errors; Ammonia; Ataxia; Child, Preschool; Coma; Diagnosis, Differenti | 1986 |
The diagnosis of ornithine transcarbamylase deficiency.
Topics: Animals; Carbamyl Phosphate; Citrulline; Coma; Female; Humans; Infant; Infant, Newborn; Intellectual | 1985 |
Hyperammonemia due to a defect in hepatic ornithine transcarbamylase.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Ammonia; Central Nervous System Diseases; Child; Child | 1972 |
Partial ornithine carbamyl transferase deficiency: an inborn error of the urea cycle presenting as orotic aciduria in a male infant.
Topics: Ammonia; Chromatography, Gas; Coma; Humans; Infant; Infusions, Parenteral; Liver; Male; Metabolism, | 1972 |