orotic acid has been researched along with Chagas Disease in 2 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inaoka, DK | 1 |
| Iida, M | 1 |
| Hashimoto, S | 1 |
| Tabuchi, T | 1 |
| Kuranaga, T | 1 |
| Balogun, EO | 1 |
| Honma, T | 1 |
| Tanaka, A | 1 |
| Harada, S | 1 |
| Nara, T | 1 |
| Kita, K | 1 |
| Inoue, M | 1 |
| Hammond, DJ | 1 |
| Gutteridge, WE | 1 |
2 other studies available for orotic acid and Chagas Disease
| Article | Year |
|---|---|
Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase.
Topics: Chagas Disease; Dihydroorotate Dehydrogenase; Dose-Response Relationship, Drug; Drug Design; Enzyme | 2017 |
Studies on the glycosomal orotate phosphoribosyl transferase of Trypanosoma cruzi.
Topics: Animals; Chagas Disease; Hydrogen-Ion Concentration; Magnesium; Microbodies; Organoids; Orotate Phos | 1983 |