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orotic acid and Carcinoma, Anaplastic

orotic acid has been researched along with Carcinoma, Anaplastic in 6 studies

Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.

Research Excerpts

ExcerptRelevanceReference
"Variants of the Lewis lung carcinoma were selected for resistance to N-(phosphonacetyl)-L-aspartic acid (PALA) by treatment of tumor-bearing mice with repetitive subcurative doses of PALA."7.66Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid. ( Ardalan, B; Cooney, DA; Cysyk, RL; Han, N; Hankerson, JG; Harley, C; Jayaram, HN; Johnson, RK; Kensler, TW; Mutter, G; Reck, LJ, 1981)
"Variants of the Lewis lung carcinoma were selected for resistance to N-(phosphonacetyl)-L-aspartic acid (PALA) by treatment of tumor-bearing mice with repetitive subcurative doses of PALA."3.66Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid. ( Ardalan, B; Cooney, DA; Cysyk, RL; Han, N; Hankerson, JG; Harley, C; Jayaram, HN; Johnson, RK; Kensler, TW; Mutter, G; Reck, LJ, 1981)
"5-Fluorouracil (FUra) is a clinically useful antineoplastic agent."1.27Phase I and clinical pharmacological evaluation of biochemical modulation of 5-fluorouracil with N-(phosphonacetyl)-L-aspartic acid. ( Casper, ES; Martin, DS; Vale, K; Williams, LJ; Young, CW, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WILCZOK, T1
HEINRIKSON, RL1
GOLDWASSER, E1
SCAIFE, JF1
POPOVIC, DA1
Casper, ES1
Vale, K1
Williams, LJ1
Martin, DS1
Young, CW1
Kensler, TW1
Mutter, G1
Hankerson, JG1
Reck, LJ1
Harley, C1
Han, N1
Ardalan, B1
Cysyk, RL1
Johnson, RK1
Jayaram, HN1
Cooney, DA1

Other Studies

6 other studies available for orotic acid and Carcinoma, Anaplastic

ArticleYear
STUDIES ON THE INCORPORATION OF HETEROLOGOUS RNA INTO NEOPLASTIC CELLS.
    Neoplasma, 1963, Volume: 10

    Topics: Animals; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Metabolism; Mice; Neoplasms; Orotic A

1963
STUDIES ON THE BIOSYNTHESIS OF 5-RIBOSYLURACIL 5'-MONOPHOSPHATE IN TETRAHYMENA PYRIFORMIS.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: Animals; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Chromatography; Diphosphates; Ligases

1964
THE EFFECT OF X-IRRADIATION ON THE METABOLISM OF RIBONUCLEIC ACID IN THE NUCLEI OF THYMOCYTES AND EHRLICH ASCITES CARCINOMA CELLS.
    Canadian journal of biochemistry, 1965, Volume: 43

    Topics: Animals; Ascites; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Nucleus; Metabolism; Nucleotides; Orotic

1965
[ANTIBIOTICS AS INHIBITORS OF RNA BIOSYNTHESIS IN NEOPLASTIC TISSUE. INCORPORATION OF 2-C-14 OROTIC ACID INTO THE RNA OF EHRLICH CARCINOMA IN VARIOUS CONCENTRATIONS OF ACTINOMYCIN D].
    Medicinski pregled, 1964, Volume: 17

    Topics: Animals; Anti-Bacterial Agents; Carbon Isotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Dactinomycin;

1964
Phase I and clinical pharmacological evaluation of biochemical modulation of 5-fluorouracil with N-(phosphonacetyl)-L-aspartic acid.
    Cancer research, 1983, Volume: 43, Issue:5

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Aspartic Acid; Blood Cell Count; Carcinoma; Drug Admin

1983
Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid.
    Cancer research, 1981, Volume: 41, Issue:3

    Topics: Amides; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carcinoma; Cell Line; Dose-Response

1981