orotic acid has been researched along with Carbon Tetrachloride Poisoning in 22 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Carbon Tetrachloride Poisoning: Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Liver and kidney samples were also taken at appropriate times after dosing and examined histologically for evidence of drug induced damage." | 1.26 | Young Scientists Award Lecture 1977: An investigation into the value of some clinical biochemical tests in the detection of minimal changes in liver morphology and function in the rat. ( Clampitt, RB, 1978) |
| "The increase in neutral lipids during CCl4 poisoning is significantly reduced by pretreatment and--somewhat less--by posttreatment with EPL." | 1.25 | Influence of phospholipids on liver damage. II. Changes in lipid content and synthesis after liver damage with carbontetrachloride and other agents. ( Bartsch, GG; Gerber, GB, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (90.91) | 18.7374 |
| 1990's | 2 (9.09) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| OHE, K | 1 |
| CARTIER, P | 3 |
| LEROUX, JP | 3 |
| KOECHER, Z | 1 |
| HABERMANNOVA, S | 1 |
| CERHOVA, M | 1 |
| SUVA, J | 1 |
| Posokhova, EA | 1 |
| Sadanobu, S | 1 |
| Takeuchi, M | 1 |
| Tezuka, M | 1 |
| Clampitt, RB | 1 |
| Lutz, RW | 1 |
| Shires, TK | 1 |
| Vácha, J | 1 |
| Seifert, J | 1 |
| Bartsch, GG | 1 |
| Gerber, GB | 1 |
| Erzsébet, FR | 1 |
| György, L | 1 |
| László, T | 1 |
| Baĭbekova, EM | 1 |
| Sultanova, LI | 1 |
| Maeda, S | 1 |
| Takeda, S | 1 |
| Miyamoto, Y | 1 |
| Aburada, M | 1 |
| Harada, M | 1 |
| Agarwal, MK | 1 |
| Gravela, E | 1 |
| Pal'tsyn, AA | 1 |
| Fujisawa, K | 1 |
| Okabe, K | 1 |
| Tanaka, K | 1 |
| Szelényi, I | 2 |
| Nemesánszky, E | 2 |
| Nagy, Z | 1 |
| Nam, LB | 1 |
| Romics, I | 1 |
| Rigó, J | 1 |
| László, G | 1 |
| Dési, I | 1 |
| Kröner, H | 1 |
| Staib, W | 1 |
| Kratzsch, KH | 1 |
| Petzold, H | 1 |
22 other studies available for orotic acid and Carbon Tetrachloride Poisoning
| Article | Year |
|---|---|
Lipid metabolism in hepatic injury. 3. Effect of orotic acid on serum and liver lipid levels in rats with subacute hepatic injury induced by the repeated injections of carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Lipid Metabolism; Lipids; Liver Disea | 1962 |
[INFLUENCE OF OROTIC ACID ON THE FREE NUCLEOTIDES IN THE RAT LIVER DURING TETRACHLORIDE POISONING].
Topics: Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Hepatitis; Hepatitis A; Live | 1964 |
[INFLUENCE OF INOSINIC ACID, ALONE OR COMBINED WITH OROTIC ACID, ON THE FREE NUCLEOTIDES IN THE RAT LIVER DURING CARBON TETRACHLORIDE POISONING].
Topics: Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Hepatitis; Hepatitis A; Inos | 1964 |
THE INFLUENCE OF OROTIC ACID ON LIVER PARENCHYMA. IV. CHANGES IN SERUM AND LIVER LIPIDS DUE TO CHRONIC CARBON TETRACHLORIDE INTOXICATION.
Topics: Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choles | 1964 |
[Effect of orotic acid, calcium pangamate, and lipamide on ultrastructural changes in lipocytes in hepatic dystrophy].
Topics: Animals; Calcium Gluconate; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1981 |
Effect of 1,3-dithia-2-thioxo-cyclopent-4-ene and its derivatives on liver injury induced by carbon tetrachloride and orotic acid in rats.
Topics: Administration, Oral; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injur | 1997 |
Young Scientists Award Lecture 1977: An investigation into the value of some clinical biochemical tests in the detection of minimal changes in liver morphology and function in the rat.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Evaluation Studies | 1978 |
Polysomal changes in rats treated with lethal doses of carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride Poisoning; Cell Nucleus; DNA; Liver; Male; Orotic Acid; Polyribosomes; | 1978 |
Biosynthesis of cytidine nucleotides and level of cytochrome P-450 in rat liver after administration of carbon tetrachloride.
Topics: Animals; Carbon Disulfide; Carbon Tetrachloride Poisoning; Cobalt; Cytochrome P-450 Enzyme System; C | 1977 |
Influence of phospholipids on liver damage. II. Changes in lipid content and synthesis after liver damage with carbontetrachloride and other agents.
Topics: Acetates; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease M | 1975 |
[Liver-protecting effects of imidazole derivatives in acute liver damage].
Topics: Acute Disease; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Imidazoles; L | 1976 |
[Structure of the liver after correction of experimental chronic hepatitis with benzonal and potassium orotate].
Topics: Animals; Barbiturates; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drug | 1990 |
Effects of gomisin A on liver functions in hepatotoxic chemicals-treated rats.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Carbon Tetrachloride Poisoning; Chemical and Drug Induced L | 1985 |
Relationship between ribonucleic acid synthesis and the mechanism of enzyme induction in mammalian liver.
Topics: Adrenalectomy; Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Endotoxins; Enzyme Inductio | 1971 |
Evidence for a reduced active life-span of messenger RNA in liver of rats poisoned with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cycloheximide; Dact | 1973 |
[An autoradiographic study of DNA and RNA synthesis in the liver cells of mice with chronic carbon tetrachloride poisoning].
Topics: Animals; Autoradiography; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug In | 1973 |
[Acute hepatic disorders].
Topics: Acute Disease; Alcoholism; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver | 1972 |
[Experimental liver lesions and its influencing by anorganic and organic magnesium salts].
Topics: Animals; Asparagine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlorid | 1971 |
[Effect of magnesium orotate glycinate on experimental ammonia poisoning].
Topics: Ammonia; Animals; Carbon Tetrachloride Poisoning; Female; Glycine; Liver; Magnesium; Male; Orotic Ac | 1971 |
[Enzyme activities and protein synthesis in damaged tissues].
Topics: Alcohol Oxidoreductases; Animals; Aspartate Aminotransferases; Carbon Isotopes; Carbon Tetrachloride | 1969 |
[Influence of orotic acid on carbon tetrachloride induced fibrosis in the rabbit].
Topics: Alkaline Phosphatase; Animals; Carbon Tetrachloride Poisoning; Liver; Liver Cirrhosis; Liver Cirrhos | 1967 |
[Influence of orotic acid and inosinemonophosphoric acid on the free nucleotides of the liver of rats poisoned by carbon tetrachloride].
Topics: Animals; Carbon Tetrachloride Poisoning; In Vitro Techniques; Liver; Male; Nucleotides; Orotic Acid; | 1966 |