orotic acid has been researched along with Body Weight in 85 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Orotic acid and estrogen, which both modify lipid metabolism in the liver, were used in male geese as tools to understand the alterations of liver lipids and plasma lipoproteins during the induction of liver steatosis." | 7.69 | Influence of orotic acid and estrogen on hepatic lipid storage and secretion in the goose susceptible to liver steatosis. ( Hermier, D; Peresson, R; Rousselot-Pailley, D; Sellier, N, 1994) |
| "Amlodipine orotate was prepared by reacting orotic acid and amlodipine to increase the dissolution rate at higher gastric pH conditions." | 5.33 | Effects of amlodipine orotate on hypertension-related complications in spontaneously hypertensive rats. ( Ahn, BO; Choi, SM; Kim, JE; Kwon, JW, 2006) |
| "Renal hypertrophy was prevented in the rats of Group 4." | 5.29 | Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet. ( Klahr, S; Reyes, AA, 1994) |
| "Arginine treatment is able to reduces attacks of hyperammonemia in boys with late-onset OTCD and to increase their growth." | 5.12 | Effects of arginine treatment on nutrition, growth and urea cycle function in seven Japanese boys with late-onset ornithine transcarbamylase deficiency. ( Adachi, M; Kanazawa, M; Kobayashi, K; Kubota, M; Kurokawa, K; Murakami, T; Murayama, K; Nagasaka, H; Ogawa, A; Ogawa, E; Takatani, T; Takayanagi, M; Yamamoto, S; Yorifuji, T, 2006) |
| "This study deals with the potential therapeutic effect of orotic acid (OA) and Mg Orotate (MgO) on myocardial degeneration and the development of congestive heart failure in cardiomyopathic (CM) hamsters of the UM-X7." | 3.70 | Effect of orotic acid and magnesium orotate on the development and progression of the UM-X7.1 hamster hereditary cardiomyopathy. ( Jasmin, G; Proschek, L, 1998) |
| "The purpose of this study was to ascertain the changes in nitrogen balance, plasma free amino acid concentrations, urinary orotic acid excretion and body weight during long-term fasting in adult obese cats." | 3.69 | Nitrogen balance, plasma free amino acid concentrations and urinary orotic acid excretion during long-term fasting in cats. ( Bee, D; Biourge, V; Fisher, C; Groff, JM; Morris, JG; Rogers, QR, 1994) |
| " Orotic acid and estrogen, which both modify lipid metabolism in the liver, were used in male geese as tools to understand the alterations of liver lipids and plasma lipoproteins during the induction of liver steatosis." | 3.69 | Influence of orotic acid and estrogen on hepatic lipid storage and secretion in the goose susceptible to liver steatosis. ( Hermier, D; Peresson, R; Rousselot-Pailley, D; Sellier, N, 1994) |
| "A lipopolysaccharide obtained in a dialyzed phenol extract from the rickettsia Coxiella burneti produced the following effects in guinea pigs after intraperitoneal injection: hyperthermia, loss of body weight, increased liver weight and concomitant lipid infiltration, elevated levels of hepatic and plasma cortisol, increased incorporation of [(3)H]orotic acid into hepatic 28S and 18S ribosomal ribonucleic acid, increased incorporation of (14)C-labeled amino acids into liver and plasma protein, and leukocytosis." | 3.65 | Some physiological and biochemical effects of a Coxiella burneti lipopolysaccharide preparation on guinea pigs. ( Baca, OG; Paretsky, D, 1974) |
| "Amlodipine orotate was prepared by reacting orotic acid and amlodipine to increase the dissolution rate at higher gastric pH conditions." | 1.33 | Effects of amlodipine orotate on hypertension-related complications in spontaneously hypertensive rats. ( Ahn, BO; Choi, SM; Kim, JE; Kwon, JW, 2006) |
| " To study the effects of PSC on liver cancer development, a daily dose of 30 mg PSC/kg body wt (PSC30) was chosen based on an initial dose-response experiment." | 1.32 | Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats. ( Bradley, G; Kankesan, J; Laconi, E; Ling, V; Rajalakshmi, S; Rao, PM; Sarma, DS; Thiessen, JJ; Vanama, R; Yusuf, A, 2003) |
| "When orotic acid was added, the contents of total lipids and triacylglycerol in the liver of the casein group were significantly higher or tended to be higher than those of the other three dietary groups." | 1.30 | Effects of dietary protein type on the response of lipid metabolism to orotic acid in rats. ( Aoyama, Y; Wada, M, 1999) |
| "Renal hypertrophy was prevented in the rats of Group 4." | 1.29 | Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet. ( Klahr, S; Reyes, AA, 1994) |
| "However, the incidence of hepatocellular carcinoma was greatly increased in animals exposed to the orotic acid diet, with 42% incidence in initiated rats given orotic acid diet for 10 weeks and up to 75% in those exposed to this diet for 40 weeks." | 1.29 | Studies on liver tumor promotion in the rat by orotic acid: dose and minimum exposure time required for dietary orotic acid to promote hepatocarcinogenesis. ( Denda, A; Laconi, E; Pani, P; Rajalakshmi, S; Rao, PM; Sarma, DS, 1993) |
| "Transplanted Morris hepatomas in Buffalo-strain rats were found to be resistant to the changes in ribonucleotide levels in rat liver caused by a high-orotate diet or an arginine-deficient diet." | 1.27 | Selective modulation of nucleotide levels in rat liver and hepatomas by high-orotate or arginine-deficient diets and by carbamoylating agents. ( Lea, MA; Luke, A; Oliphant, V, 1988) |
| "Urea synthesis was similar in experimental and control liver slices and was augmented by ornithine only in the experimental slices." | 1.26 | Ammonia metabolism in dogs with portacaval shunts. ( Altman, RP; Glasgow, AM; Schulman, JD; Stolar, CJ, 1982) |
| "Thymidine was not phosphorylated, and was believed to be catabolized." | 1.25 | Uptake of orotate and thymidine by normal and regenerating rat livers. ( Ord, MG; Stocken, LA, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 66 (77.65) | 18.7374 |
| 1990's | 11 (12.94) | 18.2507 |
| 2000's | 6 (7.06) | 29.6817 |
| 2010's | 1 (1.18) | 24.3611 |
| 2020's | 1 (1.18) | 2.80 |
| Authors | Studies |
|---|---|
| Fushimura, Y | 1 |
| Hoshino, A | 1 |
| Furukawa, S | 1 |
| Nakagawa, T | 1 |
| Hino, T | 1 |
| Taminishi, S | 1 |
| Minami, Y | 1 |
| Urata, R | 1 |
| Iwai-Kanai, E | 1 |
| Matoba, S | 1 |
| Tarasenko, TN | 1 |
| Rosas, OR | 1 |
| Singh, LN | 1 |
| Kristaponis, K | 1 |
| Vernon, H | 1 |
| McGuire, PJ | 1 |
| Murata, Y | 1 |
| Kojima, N | 1 |
| Kawashima, S | 1 |
| Kankesan, J | 1 |
| Yusuf, A | 1 |
| Laconi, E | 3 |
| Vanama, R | 1 |
| Bradley, G | 1 |
| Thiessen, JJ | 1 |
| Ling, V | 1 |
| Rao, PM | 3 |
| Rajalakshmi, S | 3 |
| Sarma, DS | 4 |
| YAMAGUCHI, Y | 1 |
| WEBER, G | 2 |
| SRIVASTAVA, SK | 2 |
| SINGHAL, RL | 2 |
| HIRD, HJ | 1 |
| FURTH, J | 1 |
| Kim, SW | 1 |
| McPherson, RL | 1 |
| Wu, G | 1 |
| Choi, SM | 1 |
| Kim, JE | 1 |
| Ahn, BO | 1 |
| Kwon, JW | 1 |
| Nagasaka, H | 1 |
| Yorifuji, T | 1 |
| Murayama, K | 1 |
| Kubota, M | 1 |
| Kurokawa, K | 1 |
| Murakami, T | 1 |
| Kanazawa, M | 1 |
| Takatani, T | 1 |
| Ogawa, A | 1 |
| Ogawa, E | 1 |
| Yamamoto, S | 1 |
| Adachi, M | 1 |
| Kobayashi, K | 1 |
| Takayanagi, M | 1 |
| Sidransky, H | 2 |
| Ulman, EA | 3 |
| Fisher, H | 1 |
| Srivastava, US | 1 |
| Majumdar, PK | 1 |
| Thakur, ML | 1 |
| Southern, LL | 1 |
| Baker, DH | 4 |
| Fejérdy, P | 1 |
| Fábián, T | 1 |
| Zelles, T | 1 |
| Kari, FW | 2 |
| Hevia, P | 1 |
| Visek, WJ | 7 |
| Glasgow, AM | 1 |
| Stolar, CJ | 1 |
| Altman, RP | 1 |
| Schulman, JD | 1 |
| Anderson, PA | 1 |
| Sherry, PA | 1 |
| Corbin, JE | 2 |
| Burns, RA | 1 |
| Milner, JA | 6 |
| Hassan, AS | 1 |
| Mulloy, AL | 1 |
| Hartman, WJ | 1 |
| Torre, PM | 1 |
| Prior, RL | 2 |
| Biourge, V | 1 |
| Groff, JM | 1 |
| Fisher, C | 1 |
| Bee, D | 1 |
| Morris, JG | 1 |
| Rogers, QR | 1 |
| Hermier, D | 1 |
| Rousselot-Pailley, D | 1 |
| Peresson, R | 1 |
| Sellier, N | 1 |
| Reyes, AA | 1 |
| Klahr, S | 1 |
| Vasudevan, S | 1 |
| Pani, P | 2 |
| Denda, A | 1 |
| Jasmin, G | 1 |
| Proschek, L | 1 |
| Su, GM | 1 |
| Sefton, RM | 1 |
| Murray, M | 1 |
| Aoyama, Y | 2 |
| Wada, M | 1 |
| Morifuji, M | 1 |
| Rogozkin, V | 1 |
| Colombo, JP | 1 |
| Berüter, J | 1 |
| Bachmann, C | 1 |
| Peheim, E | 1 |
| Novaković, MB | 1 |
| Petrović, SL | 1 |
| Rakić, LM | 1 |
| Ivanus, JJ | 1 |
| Subbiah, MT | 1 |
| Rogozkin, VA | 1 |
| Loeb, JN | 2 |
| Yeung, LL | 1 |
| Easter, RA | 2 |
| Miyasaka, H | 1 |
| Sanada, H | 1 |
| Scholz, W | 1 |
| Wolf, A | 1 |
| Kunz, W | 1 |
| Willenbrock, R | 1 |
| Steffen, C | 1 |
| Alonso, E | 1 |
| Rubio, V | 1 |
| Shibata, K | 1 |
| Murata, K | 1 |
| Hayakawa, T | 1 |
| Iwai, K | 1 |
| Lea, MA | 1 |
| Luke, A | 1 |
| Oliphant, V | 1 |
| Oussadou, L | 1 |
| Kalopissis, AD | 1 |
| Francone, OL | 1 |
| Griffaton, G | 1 |
| Benjamin, LE | 1 |
| Steele, RD | 1 |
| Gushiken, T | 1 |
| Yoshimura, N | 1 |
| Saheki, T | 1 |
| Dallman, PR | 1 |
| Manies, EC | 1 |
| Hirsch, GH | 1 |
| Hook, JB | 1 |
| Lee, CJ | 1 |
| Okonkwo, PO | 1 |
| Kinsella, JE | 1 |
| Wakeling, AE | 1 |
| Katz, RS | 1 |
| Baca, OG | 1 |
| Paretsky, D | 1 |
| Witting, LA | 1 |
| de Villers, A | 1 |
| Simard, P | 1 |
| Srivastava, U | 2 |
| Ord, MG | 1 |
| Stocken, LA | 1 |
| Irsigler, K | 1 |
| Flegel, U | 1 |
| Kühn, P | 1 |
| Schubert, H | 1 |
| Iván, E | 1 |
| Biro, L | 1 |
| Székely, L | 1 |
| Cox, R | 1 |
| Martin, JT | 1 |
| Shinozuka, H | 1 |
| Edreira, JG | 1 |
| Hirsch, RL | 1 |
| Kennedy, JA | 1 |
| De Guglielmone, AE | 1 |
| Soto, AM | 1 |
| Duvilanski, BH | 1 |
| Cutillo, S | 1 |
| Meloni, T | 1 |
| Dore, A | 1 |
| Mowat, A | 1 |
| Pausch, J | 1 |
| Keppler, D | 1 |
| Decker, K | 1 |
| Hayashi, TT | 1 |
| Kazmierowski, D | 1 |
| Vu, ML | 1 |
| Bhargava, S | 1 |
| Goswami, T | 1 |
| Davies, T | 1 |
| Kelleher, J | 1 |
| Smith, CL | 1 |
| Losowsky, MS | 1 |
| Hapke, HJ | 1 |
| Sterner, W | 1 |
| Heisler, E | 1 |
| Bräuer, H | 1 |
| Aonuma, S | 1 |
| Hama, T | 1 |
| Tamaki, N | 1 |
| Okumura, H | 1 |
| Tolentino, EM | 1 |
| Windmueller, HG | 1 |
| Lindgren, FT | 1 |
| Lossow, WJ | 1 |
| Levy, RI | 1 |
| Geel, SE | 1 |
| Timiras, PS | 1 |
| Verney, E | 1 |
| Albertini, A | 1 |
| Fiaccavento, S | 1 |
| Bonera, B | 1 |
| Sobek, V | 1 |
| Král, Z | 1 |
| Malt, RA | 1 |
| Lemaitre, DA | 1 |
| Porta, EA | 1 |
| Manning, C | 1 |
| Hartroft, WS | 1 |
| Whittle, ED | 1 |
| Potter, VR | 1 |
| Adams, DH | 1 |
| Fox, ME | 1 |
| Bonollo, L | 1 |
1 review available for orotic acid and Body Weight
| Article | Year |
|---|---|
Effects of diet and stages of development on intestinal cells and enzymes.
Topics: Aging; Aminohydrolases; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Aspar | 1971 |
2 trials available for orotic acid and Body Weight
| Article | Year |
|---|---|
Effects of arginine treatment on nutrition, growth and urea cycle function in seven Japanese boys with late-onset ornithine transcarbamylase deficiency.
Topics: Age of Onset; Amino Acids; Ammonia; Analysis of Variance; Arginine; Biomarkers; Blood Proteins; Body | 2006 |
Double-blind trial of effects of aspartic acid, orotic acid and glucose on serum bilirubin concentrations in infants born before term.
Topics: Aspartic Acid; Bilirubin; Body Weight; Clinical Trials as Topic; Gestational Age; Glucose; Humans; H | 1971 |
82 other studies available for orotic acid and Body Weight
| Article | Year |
|---|---|
Orotic acid protects pancreatic β cell by p53 inactivation in diabetic mouse model.
Topics: Animals; Apoptosis; Blood Glucose; Body Weight; Cell Line, Tumor; Cytosol; Diabetes Mellitus, Type 2 | 2021 |
A new mouse model of mild ornithine transcarbamylase deficiency (spf-j) displays cerebral amino acid perturbations at baseline and upon systemic immune activation.
Topics: Amino Acid Sequence; Amino Acids; Animals; Biological Transport; Body Weight; Brain; Disease Models, | 2015 |
Functions of a chitosan-orotic acid salt in the gastrointestinal tract.
Topics: Adjuvants, Pharmaceutic; Administration, Oral; Adsorption; Animals; Bile Acids and Salts; Body Weigh | 2003 |
Effect of PSC 833, an inhibitor of P-glycoprotein, on 1,2-dimethylhydrazine-induced liver carcinogenesis in rats.
Topics: 1,2-Dimethylhydrazine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight | 2003 |
[EFFECT OF OROTIC ACID ON PLASMA PROTEINS IN OPERATIVE STRESS].
Topics: Adrenal Glands; Amino Acids; Blood Protein Electrophoresis; Blood Proteins; Body Weight; Dietary Pro | 1963 |
ROLE OF ENZYMES IN HOMEOSTASIS. VII. EARLY EFFECTS OF CORTICOSTEROID HORMONES ON HEPATIC GLUCONEOGENIC ENZYMES, RIBONUCLEIC ACID METABOLISM, AND AMINO ACID LEVEL.
Topics: Adrenal Cortex Hormones; Amino Acids; Body Weight; Cortisone; Dactinomycin; Fructose-Bisphosphatase; | 1965 |
BEHAVIOR OF HEPATIC GLUCONEOGENIC ENZYMES, RNA METABOLISM AND AMINO ACID LEVEL IN RATS CARRYING TRANSPLANTABLE ACTH-SECRETING PITUITARY TUMORS.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Bo | 1965 |
Dietary arginine supplementation enhances the growth of milk-fed young pigs.
Topics: Amino Acids; Amino Acids, Essential; Ammonia; Animals; Animals, Newborn; Arginine; Blood Glucose; Bo | 2004 |
Effects of amlodipine orotate on hypertension-related complications in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium; Cardiomegaly; Ce | 2006 |
Biotin deficiency and orotic acid fatty liver in the rat.
Topics: Animals; Avitaminosis; Biotin; Body Weight; Diet; Fatty Liver; Female; Lipid Metabolism; Organ Size; | 1967 |
Arginine utilization of young rats fed diets with simple versus complex carbohydrates.
Topics: Animals; Arginine; Body Weight; Dextrins; Dietary Carbohydrates; Dietary Fiber; Galactans; Lipid Met | 1983 |
Brain mRNA translatability in rats: changes during long-term dietary restriction in the developmental period of life.
Topics: Aging; Animals; Autoradiography; Body Weight; Brain; Female; Food Deprivation; Orotic Acid; Poly A; | 1984 |
Arginine requirement of the young pig.
Topics: Amino Acids; Animals; Arginine; Biological Availability; Blood Urea Nitrogen; Body Weight; Diet; Nut | 1983 |
[The effect of magnesium orotate on dental hard tissue in undernourished rats].
Topics: Administration, Oral; Animals; Body Weight; Bone Development; Magnesium; Orotic Acid; Protein-Energy | 1980 |
Orotic aciduria caused by feeding excess lysine to growing rats.
Topics: Ammonia; Animals; Arginine; Body Weight; Creatinine; Eating; Lysine; Male; Orotic Acid; Rats; Rats, | 1981 |
Ammonia metabolism in dogs with portacaval shunts.
Topics: Ammonia; Animals; Arginine; Body Weight; Citrulline; Dogs; Female; Liver; Nitrogen; Organ Size; Orot | 1982 |
Nitrogen requirement of the kitten.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cats; Creatinine; Nitrogen; Nutrit | 1980 |
Arginine: an indispensable amino acid for mature dogs.
Topics: Animals; Arginine; Body Weight; Citrates; Citric Acid; Dogs; Dose-Response Relationship, Drug; Femal | 1981 |
Species specificity of arginine deficiency-induced hepatic steatosis.
Topics: Age Factors; Animals; Arginine; Body Weight; Cricetinae; Disease Susceptibility; Fatty Liver; Lipid | 1981 |
Arginine requirement of mature protein-malnourished rats for maximal rate of repletion.
Topics: Animals; Arginine; Body Composition; Body Weight; Dietary Proteins; Dose-Response Relationship, Drug | 1981 |
Dietary citrulline but not ornithine counteracts dietary arginine deficiency in rats by increasing splanchnic release of citrulline.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Blood Flow Velocity; Body Weight; Citrulline; Crea | 1994 |
Nitrogen balance, plasma free amino acid concentrations and urinary orotic acid excretion during long-term fasting in cats.
Topics: Amino Acids, Essential; Animals; Bilirubin; Body Weight; Cat Diseases; Cats; Fasting; Fatty Liver; F | 1994 |
Influence of orotic acid and estrogen on hepatic lipid storage and secretion in the goose susceptible to liver steatosis.
Topics: Animal Feed; Animals; Body Weight; Estrogens; Fatty Liver; Geese; Lipids; Lipoproteins, VLDL; Liver; | 1994 |
Dietary supplementation of L-arginine ameliorates renal hypertrophy in rats fed a high-protein diet.
Topics: Animals; Arginine; Body Weight; Creatinine; Dietary Proteins; Female; Hypertrophy; Kidney; Organ Siz | 1994 |
The development of hepatocellular carcinoma in initiated rat liver after a brief exposure to orotic acid coupled with partial hepatectomy.
Topics: Animals; Body Weight; Carcinogens; Hepatectomy; Liver; Liver Neoplasms, Experimental; Male; Organ Si | 1993 |
Studies on liver tumor promotion in the rat by orotic acid: dose and minimum exposure time required for dietary orotic acid to promote hepatocarcinogenesis.
Topics: Animals; Body Weight; Carcinogens; Carcinoma, Hepatocellular; Dose-Response Relationship, Drug; Live | 1993 |
Effect of orotic acid and magnesium orotate on the development and progression of the UM-X7.1 hamster hereditary cardiomyopathy.
Topics: Animals; Body Weight; Calcinosis; Cardiomyopathies; Cricetinae; Diet; Electrocardiography; Female; H | 1998 |
Down-regulation of rat hepatic microsomal cytochromes P-450 in microvesicular steatosis induced by orotic acid.
Topics: Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Body Weight; Cytochrome P-450 CYP2C8; Cytoc | 1999 |
Effects of dietary protein type on the response of lipid metabolism to orotic acid in rats.
Topics: Animals; Body Weight; Caseins; Cholesterol; Dietary Proteins; Dietary Supplements; Egg Proteins; Ene | 1999 |
Dietary orotic acid increases 1 ,2-diacylglycerol level and lowers superoxide dismutase activity in rat liver.
Topics: Alanine Transaminase; Animals; Body Weight; Catalase; Dietary Supplements; Diglycerides; Eating; Glu | 2002 |
Anabolic and androgenic effects of methandrostenolone ("Nerobol") during systematic physical activity in rats.
Topics: Animals; Body Weight; DNA-Directed RNA Polymerases; Electron Transport Complex IV; Leucine; Male; Me | 1975 |
Enzymes of ammonia detoxication after portacaval shunt in the rat. I. Carbamylphosphate synthetase and aspartate transcarbamylase.
Topics: Ammonia; Animals; Aspartate Carbamoyltransferase; Body Weight; Carbamoyl-Phosphate Synthase (Ammonia | 1977 |
Mechanism for fatty liver induction in rats fed arginine deficient diets.
Topics: Adenine; Animals; Arginine; Body Weight; Cholesterol; Citrates; Fatty Liver; Female; Guanine; Lipid | 1979 |
Different turnover rates of brain ribosomal ribonucleic acids in male and female rats.
Topics: Animals; Body Weight; Brain; Female; Half-Life; Kinetics; Male; Organ Size; Orotic Acid; Rats; RNA, | 1979 |
Orotic aciduria in the female rat and its relation to dietary arginine.
Topics: Aging; Ammonia; Animals; Arginine; Birth Weight; Body Weight; Citrates; Female; Litter Size; Orotic | 1978 |
Cholesterol excretion and liver cholesterol in rats during early stages of orotic acid feeding.
Topics: Animals; Bile Acids and Salts; Body Weight; Cholesterol; Feces; Female; Liver; Orotic Acid; Rats; St | 1978 |
The effect of the number of daily training sessions on skeletal muscle protein synthesis.
Topics: Animals; Body Weight; Glycogen; Leucine; Male; Microsomes; Muscle Proteins; Muscles; Orotic Acid; Ph | 1976 |
Urinary metabolites characteristic of urea-cycle amino acid deficiency.
Topics: Amino Acids; Amino Acids, Essential; Ammonia; Animal Nutritional Physiological Phenomena; Animals; A | 1975 |
Synthesis and degradation of ribosomal RNA in regenerating liver.
Topics: Animals; Body Weight; Carbon Radioisotopes; DNA; Hepatectomy; Liver; Liver Regeneration; Male; Oroti | 1975 |
Nitrogen metabolism and reproductive response of gravid swine fed an arginine-free diet during the last 84 days of gestation.
Topics: Animals; Arginine; Birth Weight; Blood Urea Nitrogen; Body Weight; Deficiency Diseases; Female; Hemo | 1976 |
Alterations of cytoplasmic enzyme activities of liver in rats fed on diets containing orotic acid with dietary fibers.
Topics: Animals; Blood Glucose; Body Weight; Cytoplasm; Diet; Dietary Fiber; Fatty Acids, Nonesterified; Ins | 1992 |
Effect of orotic acid on the generation of reactive oxygen and on lipid peroxidation in rat liver.
Topics: Administration, Oral; Animals; Body Weight; Cytochrome P-450 Enzyme System; DNA Damage; DNA, Single- | 1991 |
Orotic aciduria due to arginine deprivation: changes in the levels of carbamoyl phosphate and of other urea cycle intermediates in mouse liver.
Topics: Animals; Arginine; Body Weight; Carbamates; Carbamyl Phosphate; Citrulline; Diet; Glutamates; Liver; | 1989 |
Effect of dietary orotic acid on the levels of liver and blood NAD in rats.
Topics: Animals; Body Weight; Creatinine; Diet; DNA; Fats; Liver; Male; NAD; Niacin; Organ Size; Orotic Acid | 1985 |
Arginine needs, physiological state and usual diets. A reevaluation.
Topics: Animals; Arginine; Body Weight; Creatine; Diet; Fatty Liver; Female; Humans; Lysine; Nutritional Req | 1986 |
Selective modulation of nucleotide levels in rat liver and hepatomas by high-orotate or arginine-deficient diets and by carbamoylating agents.
Topics: Animals; Arginine; Body Weight; Diet; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred | 1988 |
Intestinal very-low-density lipoprotein secretion in the genetically obese Zucker rat.
Topics: Animals; Body Weight; Chylomicrons; Diet; Dietary Fats; Female; Intestinal Mucosa; Intestines; Lipop | 1988 |
The effect of dietary protein on nitrogen and sulfur metabolism in portacaval-shunted rats.
Topics: Amino Acids, Sulfur; Ammonia; Animals; Body Weight; Dietary Proteins; Hepatic Encephalopathy; Liver; | 1986 |
Transient hyperammonemia during aging in ornithine transcarbamylase-deficient, sparse-fur mice.
Topics: Aging; Ammonia; Animals; Body Weight; Disease Models, Animal; Hair; Liver; Mice; Mice, Mutant Strain | 1985 |
Protein deficiency: contrasting effects on DNA and RNA metabolism in rat liver.
Topics: Animals; Body Weight; Cell Division; Cell Nucleus; Dietary Proteins; DNA; DNA Nucleotidyltransferase | 1973 |
Stimulation of renal organic acid transport and protein synthesis by penicillin.
Topics: Aminohippuric Acids; Ammonium Chloride; Animals; Biological Transport, Active; Body Fluids; Body Wei | 1970 |
Biosynthesis and characteristics of brain protein and ribonucleic acid in mice subjected to neonatal infection or undernutrition.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Weight; Bra | 1970 |
Fatty livers induction by orotic acid contained in skim milk powder.
Topics: Animals; Body Weight; Diet; Eating; Fatty Liver; Female; Lipid Metabolism; Liver; Milk; Organ Size; | 1974 |
Effect of arginine deficiency on growth and intermediary metabolism in rats.
Topics: Amino Acids; Ammonia; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Ci | 1974 |
Arginine: a dispensable amino acid for postpubertal growth and pregnancy of swine.
Topics: Amino Acids; Animal Feed; Animals; Arginine; Blood Urea Nitrogen; Body Weight; Citrates; Feces; Fema | 1974 |
Some physiological and biochemical effects of a Coxiella burneti lipopolysaccharide preparation on guinea pigs.
Topics: Amino Acids; Animals; Bacteriological Techniques; Blood Glucose; Body Temperature; Body Weight; Carb | 1974 |
Fatty liver induction: effect of ethionine on polyunsaturated fatty acid synthesis.
Topics: Acetates; Animals; Body Weight; Carbon Isotopes; Cytochrome P-450 Enzyme System; Edetic Acid; Ethion | 1973 |
Biochemical changes in progressive muscular dystrophy. X. Studies on the biosynthesis of protein and RNA in cellular fractions of the skeletal muscle of normal and vitamin E deficient rabbits.
Topics: Animals; Body Weight; Carbon Isotopes; Centrifugation, Density Gradient; DNA; Leucine; Muscle Protei | 1973 |
Effects of urea in rats deprived of arginine.
Topics: Aconitic Acid; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weig | 1973 |
Uptake of orotate and thymidine by normal and regenerating rat livers.
Topics: Aging; Animals; Biological Transport, Active; Body Weight; Chromatography, Thin Layer; Hepatectomy; | 1973 |
[Does magnesium-orotate improve the effect of lipid lowering drugs?].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood Glucose; Body Weight; Cholesterol; Clofibra | 1973 |
Studies on acute methionine toxicity. II. Inhibition of ribonucleic acid synthesis in guinea pig liver by methionine and ethionine.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Body Weight; DNA-Di | 1973 |
Production of fatty liver with dietary ethanol despite orotic acid supplementation.
Topics: Alcohol Drinking; Animals; Body Weight; Diet; Disease Models, Animal; Ethanol; Fatty Liver; Liver; M | 1974 |
Neonatal undernutrition and RNA synthesis in developing rat brain.
Topics: Aging; Animals; Body Weight; Brain; Cell Nucleus; Chromatography, Thin Layer; Deficiency Diseases; D | 1974 |
Effect of orotic acid upon serum bilirubin in newborn infants with erythrocyte G-6-PD deficiency.
Topics: Administration, Oral; Bilirubin; Birth Weight; Blood Glucose; Body Weight; Erythrocytes; Exchange Tr | 1974 |
Activity and distribution of the enzymes of uridylate synthesis from orotate in animal tissues.
Topics: Age Factors; Animals; Body Weight; Brain; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Cell Frac | 1972 |
Changes in the free and membrane-bound ribosomes in the rat liver with starvation.
Topics: Animals; Bile Acids and Salts; Body Weight; Carbon Isotopes; Cell Nucleus; Centrifugation, Density G | 1972 |
Metabolism of nucleic acids and protein in the liver, brain, and kidney of female rats subjected to dietary restriction during the period of gestation as well as the period of growth, gestation, and lactation.
Topics: Animals; Body Weight; Brain; Carbon Isotopes; Diet; Female; Kidney; Lactation; Leucine; Liver; Nucle | 1972 |
The effect of orotic acid on the absorption, transport and tissue distribution of a-tocopherol in the rat.
Topics: Adipose Tissue; Adrenal Glands; Animals; Biological Transport; Blood Protein Electrophoresis; Blood | 1971 |
Toxicological studies with Kavaform.
Topics: Animals; Appetite; Blood Cell Count; Blood Coagulation; Blood Glucose; Body Weight; Dioxoles; Dogs; | 1971 |
Orotate as a beta-alanine donor for anserine and carnosine biosynthesis, and effects of actinomycin D and azauracil on their pathway.
Topics: Alanine; Amino Acids; Animals; Autoanalysis; Autoradiography; Body Weight; Carbon Isotopes; Chromato | 1969 |
Effects of cortisone on ribosomal RNA synthesis in rat liver.
Topics: Animals; Body Weight; Carbon Isotopes; Centrifugation, Density Gradient; Cortisone; DNA; Liver; Male | 1970 |
On the nature of circulating lipoproteins of intestinal origin in the rat.
Topics: Animals; Antigens; Autoanalysis; Blood Proteins; Body Weight; Cholesterol; Computers; Deficiency Dis | 1970 |
Influence of growth hormone on cerebral cortical RNA metabolism in immature hypothyroid rats.
Topics: Animals; Animals, Newborn; Body Weight; Carbon Isotopes; Centrifugation; Cerebral Cortex; DNA; Elect | 1970 |
Influence of orotic acid on liver tumorigenesis in rats ingesting ethionine, N-2-fluorenylacetamide, and 3'-methyl-dimethylaminoazobenzene.
Topics: Acetamides; Acetates; Amides; Animals; Azo Compounds; Benzene Derivatives; Body Weight; Diet; Diseas | 1970 |
Turnover of liver ribosomes in ethanol-intoxicated rats.
Topics: Alcoholic Intoxication; Animals; Arginine; Body Weight; Carbon Isotopes; DNA; Humans; Liver; Orotic | 1970 |
A salt of orotic acid and neomycin.
Topics: Animals; Body Weight; Diaphragm; Guinea Pigs; Heart; In Vitro Techniques; Kidney; Mice; Muscle Contr | 1967 |
Accretion and turnover of RNA in the renoprival kidney.
Topics: Animals; Body Weight; Carbon Isotopes; DNA; Kidney; Male; Mice; Nephrectomy; Organ Size; Orotic Acid | 1968 |
The lipotropic action of orotic acid.
Topics: Animals; Body Weight; Cholesterol; Choline Deficiency; Diet; Histocytochemistry; Liver; Male; Micros | 1968 |
Systematic oscillations in the metabolism of orotic acid in the rat adapted to a controlled feeding schedule.
Topics: Adaptation, Physiological; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Carbon | 1968 |
Some studies on rat brain microsomes in relation to growth and development.
Topics: Animals; Bile Acids and Salts; Body Weight; Brain Chemistry; Carbon Isotopes; Cerebellum; Cerebral C | 1969 |
[Influence of orotate on weight gain in rats. Contribution with reference to the dietary protein level].
Topics: Animals; Body Weight; Dietary Proteins; Orotic Acid; Protein Deficiency; Rats | 1969 |