orotic acid has been researched along with Anemia, Megaloblastic in 10 studies
Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.
Anemia, Megaloblastic: A disorder characterized by the presence of ANEMIA, abnormally large red blood cells (megalocytes or macrocytes), and MEGALOBLASTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We identified mild and isolated orotic aciduria in 11 unrelated individuals with diverse clinical signs and symptoms, the most common denominator being intellectual disability/developmental delay." | 3.85 | Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences. ( Alhaddad, B; Botto, LD; Chen, MA; Colombo, R; Coughlin, CR; Descartes, M; Grűnewald, S; Kluijtmans, LA; Maranda, B; Mills, PB; Pai, EF; Pitt, J; Pontoglio, A; Potente, C; Rodenburg, R; Sampath, S; Tiller, GE; Wevers, RA; Wortmann, SB; Yuzyuk, T, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grohmann, K | 1 |
| Lauffer, H | 1 |
| Lauenstein, P | 1 |
| Hoffmann, GF | 1 |
| Seidlitz, G | 1 |
| Häberle, J | 1 |
| Wortmann, SB | 1 |
| Chen, MA | 1 |
| Colombo, R | 1 |
| Pontoglio, A | 1 |
| Alhaddad, B | 1 |
| Botto, LD | 1 |
| Yuzyuk, T | 1 |
| Coughlin, CR | 1 |
| Descartes, M | 1 |
| Grűnewald, S | 1 |
| Maranda, B | 1 |
| Mills, PB | 1 |
| Pitt, J | 1 |
| Potente, C | 1 |
| Rodenburg, R | 1 |
| Kluijtmans, LA | 1 |
| Sampath, S | 1 |
| Pai, EF | 1 |
| Wevers, RA | 1 |
| Tiller, GE | 1 |
| Bailey, CJ | 1 |
| BUSSI, L | 1 |
| ERIDANI, S | 1 |
| TAGLIORETTI, D | 1 |
| HUGULEY, CM | 1 |
| BAIN, JA | 1 |
| RIVERS, SL | 1 |
| SCOGGINS, RB | 1 |
| FALLON, HJ | 1 |
| SMITH, LH | 1 |
| GRAHAM, JB | 1 |
| BURNETT, CH | 1 |
| BECROFT, DM | 1 |
| PHILLIPS, LI | 1 |
| Cooper, BA | 1 |
| Baker, SJ | 1 |
2 reviews available for orotic acid and Anemia, Megaloblastic
| Article | Year |
|---|---|
Orotic aciduria and uridine monophosphate synthase: a reappraisal.
Topics: Adult; Anemia, Megaloblastic; Child; Child, Preschool; Humans; Infant; Kinetics; Metabolic Networks | 2009 |
Megaloblastic anaemia and disorders affecting utilisation of vitamin B12 and folate in childhood.
Topics: Adolescent; Adult; Anemia, Hemolytic; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Pernicious; | 1976 |
8 other studies available for orotic acid and Anemia, Megaloblastic
| Article | Year |
|---|---|
Hereditary orotic aciduria with epilepsy and without megaloblastic anemia.
Topics: Anemia, Megaloblastic; Child, Preschool; Epilepsy; Humans; Male; Metabolic Diseases; Multienzyme Com | 2015 |
Of ammonia and orotic acid and their importance for clinical neuropediatrics.
Topics: Anemia, Megaloblastic; Epilepsy; Humans; Male; Metabolic Diseases; Multienzyme Complexes; Orotate Ph | 2015 |
Mild orotic aciduria in UMPS heterozygotes: a metabolic finding without clinical consequences.
Topics: Anemia, Megaloblastic; Child; Child, Preschool; Female; Heterozygote; Humans; Infant; Intellectual D | 2017 |
[Orotic acid and vitamin B12 in the treatment of some cases of megaloblastic anemia].
Topics: Anemia; Anemia, Megaloblastic; Hematinics; Humans; Orotic Acid; Riboflavin; Vitamin B 12; Vitamin B | 1958 |
Refractory megaloblastic anemia associated with excretion of orotic acid.
Topics: Anemia; Anemia, Megaloblastic; Biological Transport; Body Fluids; Humans; Orotic Acid | 1959 |
A GENETIC STUDY OF HEREDITARY OROTIC ACIDURIA.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Carboxy-Lyases; Genetics, Medical; Humans; Leukop | 1964 |
HEREDITARY OROTIC ACIDURIA AND MEGALOBLASTIC ANAEMIA: A SECOND CASE, WITH RESPONSE TO URIDINE.
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow Examination; Child; Fluids and Secret | 1965 |
Nutrition and diseases of the blood: the megaloblastic anaemias.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adult; Anemia, Macrocytic; Anemia, Megalo | 1975 |