Page last updated: 2024-10-19

orotic acid and Adenocarcinoma

orotic acid has been researched along with Adenocarcinoma in 7 studies

Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE.
orotic acid : A pyrimidinemonocarboxylic acid that is uracil bearing a carboxy substituent at position C-6.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"Deazauridine treatment of L1210 cells in culture stimulated the uptake of deoxycytidine-3H into DNA while inhibiting the uptake of 3H-labeled deoxyuridine, thymidine, deoxyadenosine, and deoxyguanosine."1.25The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine. ( Brockman, RW; Nelson, JA; Rose, LM; Schabel, FM; Shaddix, SC; Williams, M, 1975)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Houghton, JA1
Houghton, PJ1
Duley, JA1
Nethersell, AB1
Brockman, RW1
Shaddix, SC1
Williams, M1
Nelson, JA1
Rose, LM1
Schabel, FM1
Erichsen, C1
Christensson, PI1
Jönsson, PE1
Stenram, U1
Bresnick, E1
Mainigi, KD1
Mayfield, ED1
Morris, HP1
Clifton, KH1
Yatvin, MB1
Handschumacher, RE1

Other Studies

7 other studies available for orotic acid and Adenocarcinoma

ArticleYear
Elucidation of pathways of 5-fluorouracil metabolism in xenografts of human colorectal adenocarcinoma.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:6

    Topics: Adenocarcinoma; Allopurinol; Animals; Colonic Neoplasms; Female; Fluorouracil; Humans; Hypoxanthines

1983
Delayed hypersensitivity to 5-fluorouracil associated with reduced dihydropyrimidine dehydrogenase (DPD) activity.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Creatinine; Dihydrouracil Dehydrogenase (NADP

1998
The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine.
    Annals of the New York Academy of Sciences, 1975, Aug-08, Volume: 255

    Topics: 3-Deazauridine; Adenocarcinoma; Animals; Cell Line; Cytarabine; Deoxycytidine; Deoxyribonucleotides;

1975
Effect of hepatic artery ligation on the incorporation of 3H-orotic acid into an adenocarcinoma transplanted to rat liver.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 1986, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Animals; DNA; Female; Hepatic Artery; Infusions, Parenteral; Liver Circulation; Live

1986
Activities of enzymes of pyrimidine nucleotide synthesis in slowly growing kidney tumors.
    Cancer research, 1969, Volume: 29, Issue:11

    Topics: Adenocarcinoma; Animals; Carbon Isotopes; Kidney; Kidney Neoplasms; Male; Neoplasm Transplantation;

1969
Cell population growth and cell loss in the MTG-B mouse mammary carcinoma.
    Cancer research, 1970, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Animals; Cell Division; DNA, Neoplasm; Idoxuridine; Iodine Radioisotopes; Mammary Ne

1970
Conference on obstacles to the control of acute leukemia. Formal discussion: some enzymatic considerations in combination chemotherapy.
    Cancer research, 1965, Volume: 25, Issue:9

    Topics: Adenocarcinoma; Animals; Antimetabolites; Dogs; Drug Synergism; Enzymes; In Vitro Techniques; Leukem

1965