Page last updated: 2024-08-22

ornithylaspartate and Encephalopathy, Hepatic

ornithylaspartate has been researched along with Encephalopathy, Hepatic in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (10.96)18.2507
2000's20 (27.40)29.6817
2010's42 (57.53)24.3611
2020's3 (4.11)2.80

Authors

AuthorsStudies
Boutros, S; Saab, S; Winters, A; Yanny, B1
Mahpour, NY; Pioppo-Phelan, L; Reja, M; Rustgi, VK; Tawadros, A1
Alimirah, M; Gordon, SC; Sadiq, O1
Goyal, O; Kaur, N; Kishore, H; Sharma, BC; Sidhu, SS1
Arias, N; Hadjihambi, A; Jalan, R; Sheikh, M1
Rathi, S; Taneja, S1
Dahale, AS; Sachdeva, S; Sharma, BC; Srivastava, S; Varakanahalli, S1
Gluud, LL; Goh, ET; Morgan, MY; Sidhu, SS; Stokes, CS; Vilstrup, H1
Cai, XJ; Hu, CM; Wang, L1
Abdo-Francis, JM; Alla, SN; Camacho-Aguilera, J; Higuera-de-la-Tijera, F; Jiménez-Ponce, F; Pérez-Hernández, JL; Salas-Gordillo, F; Servín-Caamaño, AI1
Butterworth, RF2
Kircheis, G; Lüth, S1
Butterworth, RF; McPhail, MJW1
Alsahhar, JS; Rahimi, RS1
Bogomolov, PO; Buyeverov, AO; Matsievich, MV; Mayev, IV; Uvarova, OV1
Bai, M; Fan, D; Han, G; Qi, X; Yang, Z1
Crossey, MM; Dhanjal, NS; Dresner, MA; Fitzpatrick, JA; Grover, VP; Leech, R; McPhail, MJ; Pflugrad, H; Saxby, BK; Taylor-Robinson, SD; Thomas, HC; Waldman, AD; Wesnes, K1
Wang, RH; Xiang, JF; Yi, J; Zhong, XN; Zhou, BY; Zhou, ZW1
Kutepov, DE; Pasechnik, IN; Sal'nikov, PS; Vershinina, MG1
Bai, M; Bai, W; Cai, H; Fan, D; Guo, W; Han, G; He, C; Liu, L; Niu, J; Qi, X; Tie, J; Wang, J; Wang, Z; Wu, K; Xia, J; Yang, Z; Yin, Z1
Manzhaliĭ, EH; Moĭseienko, VO; Nykula, TD; Solonovych, OS1
Braddock, M; Chen, YP; Huang, GQ; Huang, S; Lin, YQ; Shi, KQ; Wang, LR; Zheng, MH; Zhu, GQ1
Utzt, MJ1
Henderson, PK; Herrera, JL1
Sussman, NL1
Petersen, KU1
Ahn, JO; Chung, JY; Han, SM; Hwang, CY; Lee, YH; Li, Q; Youn, HY1
Baranova, EN; Maksimov, SA; Plotnikova, EY1
Achermann, P; Amodio, P; Angeli, P; Garrido, M; Montagnese, S; Raduazzo, D; Skorucak, J; Spinelli, G; Turco, M1
Bak-Bol, A; Cook, NA; Cox, IJ; Crossey, MM; Dhanjal, NS; Fitzpatrick, JA; Grover, VP; McPhail, MJ; Morgan, MY; Saxby, BK; Southern, L; Taylor-Robinson, SD; Waldman, AD; Williams, R; Wylezinska-Arridge, M1
Kircheis, G1
Chen, YP; Jiang, Q; Jiang, XH; Zheng, MH1
Ahmad, I; Alam, A; Butt, AK; Dilshad, A; Khan, AA; Malik, K; Sarwar, S; Shafqat, F1
Ferenci, P; Gangl, A; König, F; Mittermaier, C; Peck-Radosavljevic, M; Schmid, M1
Ameri, AA1
Abdo-Francis, JM; Hernández-Vásquez, JR; Hinojosa-Ruiz, A; Pérez-Hernández, JL1
Jalan, R; Noiret, L; Olde Damink, SW; Wright, G1
Ndraha, S; Simadibrata, M1
Krüger-Jansen, C; Lambert-Baumann, J; Oehler, G; Ong, JP; Younossi, ZM1
Hasan, I; Ndraha, S; Simadibrata, M1
Mittal, VV; Sarin, SK; Sharma, BC; Sharma, P1
Abbas, Z; Abid, S; Hamid, S; Islam, M; Jafri, W; Mumtaz, K; Shah, HA1
Evdokimov, VV; Evdokimova, AG; Kovalenko, EV; Radzevich, AÉ; Tomova, AV; Zhukolenko, LV1
Blanco Vela, CI; Poo Ramírez, JL1
Abdo Francis, JM; Higuera de la Tijera, F; Pérez Hernández, JL; Serralde-Zúñiga, AE1
Fehérvári, I; Gerlei, Z; Görög, D; Kóbori, L; Nemes, B1
Wang, YM1
Dahl, Sv; Häussinger, D; Kircheis, G; Wettstein, M1
Carmona Soria, I; García Montes, JM; Herrerías Gutiérrez, JM; Jiménez Sáenz, M; Quero Guillén, JC1
Häussinger, D; Wettstein, M1
Bautista, JD; Grande, L; Ramos Guerrero, RM; Romero Gómez, M; Sánchez Muñoz, D1
Gregor, M; Hass, HG; Hösl, F; Kaiser, S; Nägele, T; Seeger, U1
Bernauer, E; Finsterer, J1
Chen, CH; Chen, MF; Gao, XC; Li, RC1
Iberer, F; Portugaller, HR; Stadlbauer, V; Stauber, RE; Stiegler, P; Tauss, J1
Blei, A; Grüngreiff, K; Jalan, R; Kircheis, G; Marchesini, G; Morgan, MY; Riggio, O; Weissenborn, K1
Dobkes, AL; Ermolov, SIu; Ermolova, TV; Kolesnikov, ME; Ovchinnikova, EV; Shabrov, AV1
Bueverov, AO; Nadinskaia, MIu; Podymova, SD1
Held, C; Kircheis, G; Krüger, B1
Eisenburg, J1
Albrecht, J; Hilgier, W; Januszewski, S; Quack, G1
Jalan, R; Seery, JP; Taylor-Robinson, SD1
Berndt, H; Buchner, M; Görtelmeyer, R; Held, C; Hendricks, R; Kircheis, G; Krüger, B; Kuklinski, B; Meister, H; Nilius, R; Otto, HJ; Rink, C; Rösch, W; Stauch, S1
Adler, G; Beckh, K; Ditschuneit, H; Görtelmeyer, R; Hendricks, R; Heuser, A; Karoff, C; Kircheis, G; Malfertheiner, P; Mayer, D; Rösch, W; Stauch, S; Steffens, J1
Butterworth, RF; Kircheis, G; Michalak, A; Pannunzio, P; Quack, G; Rose, C; Therrien, G1
Koczorek, M1
Delcker, A; Mihm, U; Pilatus, U; Raab, P; Rusch, O; Turowski, B; Zanella, FE; Zeuzem, S1
Dicheva, DT; Iakovenko, EI; Lebedeva, EG; Maev, IV; V'iuchnova, ES1

Reviews

27 review(s) available for ornithylaspartate and Encephalopathy, Hepatic

ArticleYear
Hepatic Encephalopathy Challenges, Burden, and Diagnostic and Therapeutic Approach.
    Clinics in liver disease, 2019, Volume: 23, Issue:4

    Topics: Amino Acids, Branched-Chain; Ammonia; Caregivers; Cost of Illness; Dipeptides; Embolization, Therapeutic; Gastrointestinal Agents; Hepatic Encephalopathy; Hospitalization; Humans; Lactulose; Neomycin; Patient Readmission; Rifaximin; Severity of Illness Index; Sodium Benzoate; Sorption Detoxification; Zinc

2019
Pharmacologic Management of Hepatic Encephalopathy.
    Clinics in liver disease, 2020, Volume: 24, Issue:2

    Topics: Acarbose; Amino Acids, Branched-Chain; Anti-Bacterial Agents; Dipeptides; Fecal Microbiota Transplantation; Flumazenil; GABA Modulators; Glycerol; Glycoside Hydrolase Inhibitors; Hepatic Encephalopathy; Humans; Lactulose; Laxatives; Phenylbutyrates; Probiotics; Rifaximin

2020
Novel Therapies in Hepatic Encephalopathy.
    Clinics in liver disease, 2020, Volume: 24, Issue:2

    Topics: Acetylcarnitine; Albumins; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Flumazenil; GABA Modulators; Glycerol; Hepatic Encephalopathy; Humans; Nootropic Agents; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Surface-Active Agents

2020
Hepatic encephalopathy: a critical current review.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Albumins; Ammonia; Anti-Bacterial Agents; Bile Acids and Salts; Brain; Brain Edema; Cognitive Dysfunction; Dipeptides; Energy Metabolism; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Ornithine; Portasystemic Shunt, Surgical; Prognosis; Psychometrics; Severity of Illness Index; Synaptic Transmission

2018
L-ornithine L-aspartate for prevention and treatment of hepatic encephalopathy in people with cirrhosis.
    The Cochrane database of systematic reviews, 2018, May-15, Volume: 5

    Topics: Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Quality of Life; Randomized Controlled Trials as Topic

2018
Pharmacokinetic and Pharmacodynamic Properties of L-Ornithine L-Aspartate (LOLA) in Hepatic Encephalopathy.
    Drugs, 2019, Volume: 79, Issue:Suppl 1

    Topics: Ammonia; Animals; Brain; Dipeptides; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Muscles; Rats; Signal Transduction

2019
L-Ornithine L-Aspartate (LOLA) for Hepatic Encephalopathy in Cirrhosis: Results of Randomized Controlled Trials and Meta-Analyses.
    Drugs, 2019, Volume: 79, Issue:Suppl 1

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Secondary Prevention; Systematic Reviews as Topic; Treatment Outcome

2019
Updates on the pathophysiology and therapeutic targets for hepatic encephalopathy.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Frailty; Gastrointestinal Agents; Gastrointestinal Microbiome; Glycerol; Hepatic Encephalopathy; Humans; Hypertension, Portal; Lactulose; Liver Cirrhosis; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Rifaximin; Trace Elements; Zinc

2019
Beneficial effects of L-ornithine L-aspartate for prevention of overt hepatic encephalopathy in patients with cirrhosis: a systematic review with meta-analysis.
    Metabolic brain disease, 2020, Volume: 35, Issue:1

    Topics: Clinical Trials as Topic; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Treatment Outcome

2020
l-ornithine-l-aspartate for hepatic encephalopathy in patients with cirrhosis: a meta-analysis of randomized controlled trials.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:5

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Randomized Controlled Trials as Topic; Treatment Outcome

2013
Systematic review with network meta-analysis: the comparative effectiveness and safety of interventions in patients with overt hepatic encephalopathy.
    Alimentary pharmacology & therapeutics, 2015, Volume: 41, Issue:7

    Topics: Amino Acids, Branched-Chain; Ammonia; Dipeptides; Disaccharides; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Mental Health; Neomycin; Randomized Controlled Trials as Topic; Rifamycins; Rifaximin

2015
Should We Treat Minimal/Covert Hepatic Encephalopathy, and with What?
    Clinics in liver disease, 2015, Volume: 19, Issue:3

    Topics: Dipeptides; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Patient Selection; Probiotics; Rifamycins; Rifaximin; Severity of Illness Index; Sickness Impact Profile

2015
Treatment of Overt Hepatic Encephalopathy.
    Clinics in liver disease, 2015, Volume: 19, Issue:3

    Topics: Amino Acids, Branched-Chain; Ammonia; Arteriovenous Fistula; Dipeptides; Gastrointestinal Agents; Glycerol; Hepatic Encephalopathy; Humans; Lactulose; Liver Failure; Malnutrition; Ornithine; Phenylbutyrates; Probiotics; Rifamycins; Rifaximin

2015
[HEPATIC ENCEPHALOPATHY AND TISSUE ZINC LEVELS IN LIVER DISEASE, DIAGNOSIS AND TREATMENT].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2015, Issue:7

    Topics: Dipeptides; Hepatic Encephalopathy; Humans; Zinc

2015
Current state of knowledge of hepatic encephalopathy (Part V): clinical efficacy of L-ornithine-L-aspartate in the management of HE.
    Metabolic brain disease, 2016, Volume: 31, Issue:6

    Topics: Animals; Dipeptides; Disease Management; Drug Administration Routes; Health Knowledge, Attitudes, Practice; Hepatic Encephalopathy; Humans; Randomized Controlled Trials as Topic; Treatment Outcome

2016
L-Ornithine-l-aspartate in the management of hepatic encephalopathy: a meta-analysis.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:1

    Topics: Dipeptides; Hepatic Encephalopathy; Humans; Patient Selection; Randomized Controlled Trials as Topic; Severity of Illness Index; Treatment Outcome

2009
Interorgan ammonia metabolism in liver failure: the basis of current and future therapies.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31, Issue:2

    Topics: Adipose Tissue; Amino Acids; Ammonia; Arginine; Brain; Dipeptides; Glutamate-Ammonia Ligase; Glutaminase; Hepatic Encephalopathy; Humans; Hyperammonemia; Intestinal Mucosa; Kidney; Liver; Liver Failure; Lung; Muscles; Phenylbutyrates; Sodium Benzoate

2011
Critical analysis of studies evaluating the efficacy of infusion of L-ornithine L-aspartate in clinical hepatic encephalopathy in patients with liver failure.
    Annals of hepatology, 2011, Volume: 10 Suppl 2

    Topics: Adult; Aged; Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Failure; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome

2011
[Hepatic encephalopathy and liver transplantation].
    Magyar sebeszet, 2012, Volume: 65, Issue:2

    Topics: Ammonia; Anti-Infective Agents; Colon; Dipeptides; Disaccharides; End Stage Liver Disease; Evidence-Based Medicine; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Hungary; Hydrogen-Ion Concentration; Lactobacillus; Lactulose; Laxatives; Liver Cirrhosis; Liver Transplantation; Metronidazole; Neomycin; Rifamycins; Rifaximin; Severity of Illness Index; Sugar Alcohols; Systemic Inflammatory Response Syndrome; Treatment Outcome

2012
[Researching progress of prevention and treatment of hepatic failure encephalopathy].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:4

    Topics: Animals; Brain Edema; Cerebrovascular Circulation; Dipeptides; Hepatic Encephalopathy; Humans; Naloxone

2002
Clinical efficacy of L-ornithine-L-aspartate in the management of hepatic encephalopathy.
    Metabolic brain disease, 2002, Volume: 17, Issue:4

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Muscular Diseases; Severity of Illness Index

2002
[Hepatic encephalopathy--therapy].
    Deutsche medizinische Wochenschrift (1946), 2003, Dec-12, Volume: 128, Issue:50

    Topics: Administration, Oral; Ammonia; Anti-Bacterial Agents; Diet, Protein-Restricted; Dipeptides; Flumazenil; GABA Modulators; Hepatic Encephalopathy; Humans; Liver Diseases

2003
[New concepts in the physiopathology of hepatic encephalopathy and therapeutic prospects].
    Gastroenterologia y hepatologia, 2004, Volume: 27 Suppl 1

    Topics: Ammonia; Brain; Brain Edema; Dipeptides; Flumazenil; Glutaminase; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Inflammation; Intestine, Small; Kidney; Memantine; Models, Molecular; Nerve Tissue Proteins; Nitric Oxide

2004
The treatment of hepatic encephalopathy.
    Metabolic brain disease, 2007, Volume: 22, Issue:3-4

    Topics: Amino Acids, Branched-Chain; Anti-Bacterial Agents; Dipeptides; Hepatic Encephalopathy; Humans; Lactulose; Sugar Alcohols; Zinc

2007
[Ornithine aspartate in hepatic encephalopathy: an established new therapeutic approach. Overview and results of current randomized studies].
    Zeitschrift fur arztliche Fortbildung, 1994, Volume: 88, Issue:9

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Function Tests; Randomized Controlled Trials as Topic; Treatment Outcome

1994
[Hepatic minimal encephalopathy. The most frequently overlooked, clinically occult "metabolic syndrome" on the cirrhosis patient].
    Fortschritte der Medizin, 1996, Apr-30, Volume: 114, Issue:12

    Topics: Ammonia; Arginine; Dipeptides; Hepatic Encephalopathy; Humans; Lactulose; Neuropsychological Tests; Prognosis; Psychometrics

1996
Review article: pathogenesis and treatment of chronic hepatic encephalopathy.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Cerebral Cortex; Diet; Dipeptides; Disaccharides; Disease Models, Animal; Dopamine Agonists; Energy Metabolism; GABA Agents; Hepatic Encephalopathy; Humans; In Vitro Techniques; Intestinal Absorption; Neurotoxins; Synaptic Transmission; Tomography, Emission-Computed

1996

Trials

16 trial(s) available for ornithylaspartate and Encephalopathy, Hepatic

ArticleYear
L-ornithine L-aspartate in bouts of overt hepatic encephalopathy.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:2

    Topics: Adult; Dipeptides; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Interleukins; Length of Stay; Male; Middle Aged; Prospective Studies

2018
Secondary prophylaxis of hepatic encephalopathy in cirrhosis of liver: a double-blind randomized controlled trial of L-ornithine L-aspartate versus placebo.
    European journal of gastroenterology & hepatology, 2018, Volume: 30, Issue:8

    Topics: Adult; Ammonia; Biomarkers; Chi-Square Distribution; Dipeptides; Double-Blind Method; Female; Flicker Fusion; Hepatic Encephalopathy; Humans; India; Kaplan-Meier Estimate; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neuropsychological Tests; Odds Ratio; Psychometrics; Recurrence; Risk Factors; Secondary Prevention; Sickness Impact Profile; Tertiary Care Centers; Time Factors; Treatment Outcome

2018
Primary Prophylaxis to Prevent the Development of Hepatic Encephalopathy in Cirrhotic Patients with Acute Variceal Bleeding.
    Canadian journal of gastroenterology & hepatology, 2018, Volume: 2018

    Topics: Acute Disease; Adult; Dipeptides; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Agents; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Male; Middle Aged; Rifaximin

2018
[Ornithine aspartate and naloxone combined therapy for hepatic encephalopathy affects cognitive function, prognosis, and neuropeptide levels].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2013, Volume: 21, Issue:5

    Topics: Adult; Dipeptides; Female; Hepatic Encephalopathy; Humans; Male; Middle Aged; Naloxone; Neuropeptides; Prognosis

2013
Randomised clinical trial: L-ornithine-L-aspartate reduces significantly the increase of venous ammonia concentration after TIPSS.
    Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:1

    Topics: Adult; Ammonia; Dipeptides; Female; Hepatic Encephalopathy; Humans; Kidney Function Tests; Liver Function Tests; Male; Middle Aged; Portasystemic Shunt, Transjugular Intrahepatic; Postprandial Period; Psychometrics; Treatment Outcome

2014
L-ornithine-L-aspartate infusion efficacy in hepatic encephalopathy.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2008, Volume: 18, Issue:11

    Topics: Adult; Aged; Ammonia; Cognition; Dipeptides; Female; Health Status Indicators; Hepatic Encephalopathy; Humans; Hyperammonemia; Infusions, Intravenous; Liver Cirrhosis; Male; Middle Aged; Postprandial Period

2008
A double-blind, randomized, placebo-controlled trial of intravenous L-ornithine-L-aspartate on postural control in patients with cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:4

    Topics: Aged; Ammonia; Biopsy, Needle; Dipeptides; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Hepatic Encephalopathy; Humans; Immunohistochemistry; Infusions, Intravenous; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Pilot Projects; Postural Balance; Psychometrics; Reference Values; Risk Assessment; Sensation Disorders; Severity of Illness Index; Statistics, Nonparametric; Survival Rate; Treatment Outcome

2010
Oral L-ornithine-L-aspartate improves health-related quality of life in cirrhotic patients with hepatic encephalopathy: an open-label, prospective, multicentre observational study.
    Clinical drug investigation, 2011, Volume: 31, Issue:4

    Topics: Administration, Oral; Adult; Aged; Dipeptides; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Prospective Studies; Quality of Life

2011
The effect of L-ornithine L-aspartate and branch chain amino acids on encephalopathy and nutritional status in liver cirrhosis with malnutrition.
    Acta medica Indonesiana, 2011, Volume: 43, Issue:1

    Topics: Adult; Aged; Albumins; Amino Acids, Branched-Chain; Ammonia; Dietary Proteins; Dipeptides; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Malnutrition; Middle Aged; Nutritional Status; Young Adult

2011
A randomized controlled trial comparing lactulose, probiotics, and L-ornithine L-aspartate in treatment of minimal hepatic encephalopathy.
    European journal of gastroenterology & hepatology, 2011, Volume: 23, Issue:8

    Topics: Adult; Ammonia; Dipeptides; Female; Hepatic Encephalopathy; Humans; Lactulose; Male; Middle Aged; Neuropsychological Tests; Probiotics; Psychometrics; Quality of Life; Severity of Illness Index; Treatment Outcome

2011
Efficacy of L-ornithine-L-aspartate as an adjuvant therapy in cirrhotic patients with hepatic encephalopathy.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2011, Volume: 21, Issue:11

    Topics: Anti-Infective Agents; Dipeptides; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Agents; Glucose; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Lactulose; Length of Stay; Liver Cirrhosis; Male; Metronidazole; Middle Aged; Prospective Studies; Treatment Outcome

2011
[Therapeutic effect of L-ornithine-L-aspartate on liver cirrhosis complicated by hepatic encephalopathy].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:6

    Topics: Dipeptides; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Cirrhosis; Male; Middle Aged

2005
[The treatment of hepatic encephalopathy with Hepa-Mertz].
    Terapevticheskii arkhiv, 1995, Volume: 67, Issue:6

    Topics: Ammonia; Biomarkers; Chronic Disease; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Psychomotor Performance; Time Factors

1995
Therapeutic efficacy of L-ornithine-L-aspartate infusions in patients with cirrhosis and hepatic encephalopathy: results of a placebo-controlled, double-blind study.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:6

    Topics: Adult; Aged; Ammonia; Dipeptides; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Cirrhosis; Male; Mental Health; Middle Aged; Placebos; Veins

1997
Oral L-ornithine-L-aspartate therapy of chronic hepatic encephalopathy: results of a placebo-controlled double-blind study.
    Journal of hepatology, 1998, Volume: 28, Issue:5

    Topics: Administration, Oral; Adult; Ammonia; Dietary Proteins; Dipeptides; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Placebos; Postprandial Period

1998
[The response to combined therapy of hepatic encephalopathy in patients with hepatic cirrhosis].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:5

    Topics: Adult; Dipeptides; Drug Therapy, Combination; Female; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Male; Middle Aged

2002

Other Studies

30 other study(ies) available for ornithylaspartate and Encephalopathy, Hepatic

ArticleYear
Terminating and episode of overt hepatic encephalopathy: L-ornithine-L-aspartate may have some role.
    Hepatology (Baltimore, Md.), 2018, Volume: 67, Issue:2

    Topics: Aspartic Acid; Dipeptides; Hepatic Encephalopathy; Humans; Ornithine

2018
Efficacy of different drugs in the treatment of minimal hepatic encephalopathy: A network meta-analysis involving 826 patients based on 10 randomized controlled trials.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:10

    Topics: Acetylcarnitine; Adult; Ammonia; Dipeptides; Female; Hepatic Encephalopathy; Humans; Lactulose; Male; Middle Aged; Network Meta-Analysis; Neuroprotective Agents; Probiotics; Randomized Controlled Trials as Topic; Rifaximin; Serum Albumin; Treatment Outcome

2018
L-Ornithine L-Aspartate (LOLA) for the Treatment of Hepatic Encephalopathy in Cirrhosis: Novel Insights and Translation to the Clinic.
    Drugs, 2019, Volume: 79, Issue:Suppl 1

    Topics: Astrocytes; Dipeptides; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Cirrhosis; Translational Research, Biomedical

2019
Possibilities of therapeutic correction of hyperammonemia and minimal hepatic encephalopathy in patients with chronic hepatitis C at the pre-cirrhotic stage.
    Terapevticheskii arkhiv, 2019, Mar-18, Volume: 91, Issue:2

    Topics: Adult; Ammonia; Case-Control Studies; Dipeptides; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Hyperammonemia; Male; Treatment Outcome

2019
Modulation of neural activation following treatment of hepatic encephalopathy.
    Neurology, 2013, Mar-12, Volume: 80, Issue:11

    Topics: Administration, Oral; Adult; Brain; Dipeptides; Female; Hepatic Encephalopathy; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Nerve Net; Psychomotor Performance; Treatment Outcome

2013
[Comparative effectiveness of different treatment methods of liver failure].
    Khirurgiia, 2014, Issue:3

    Topics: Comparative Effectiveness Research; Dipeptides; Extracorporeal Circulation; Female; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Liver Failure; Male; Middle Aged; Monitoring, Physiologic; Plasma Exchange; Sorption Detoxification; Treatment Outcome

2014
[Pathogenesis, diagnosis and treatment of hepatic encephalopathies in patients with liver cirrhosis].
    Likars'ka sprava, 2014, Issue:11

    Topics: Adult; Aged; Ammonia; Citric Acid Cycle; Dipeptides; Event-Related Potentials, P300; Female; Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Protective Agents; Severity of Illness Index

2014
[In Process Citation].
    MMW Fortschritte der Medizin, 2015, Volume: 157 Suppl 2

    Topics: Ammonia; Clinical Trials as Topic; Dipeptides; Early Diagnosis; Early Medical Intervention; Evidence-Based Medicine; Hepatic Encephalopathy; Humans; Lactulose; Prognosis; Rifamycins; Rifaximin

2015
[Options in the treatment of hepatic encephalopathy].
    Medizinische Monatsschrift fur Pharmazeuten, 2015, Volume: 38, Issue:5

    Topics: Amino Acids, Branched-Chain; Ammonia; Anti-Bacterial Agents; Dipeptides; Hepatic Encephalopathy; Humans; Rifamycins; Rifaximin

2015
Hyperammonemic hepatic encephalopathy management through L-ornithin-L-aspartate administration in dogs.
    Journal of veterinary science, 2016, Sep-30, Volume: 17, Issue:3

    Topics: Ammonia; Animals; Dipeptides; Dog Diseases; Dogs; Female; Hepatic Encephalopathy; Hyperammonemia; Male

2016
Vigilance and wake EEG architecture in simulated hyperammonaemia: a pilot study on the effects of L-Ornithine-L-Aspartate (LOLA) and caffeine.
    Metabolic brain disease, 2016, Volume: 31, Issue:4

    Topics: Adult; Brain; Caffeine; Dipeptides; Electroencephalography; Female; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Cirrhosis; Male; Middle Aged; Neuropsychological Tests; Pilot Projects; Wakefulness

2016
A longitudinal study of patients with cirrhosis treated with L-ornithine L-aspartate, examined with magnetization transfer, diffusion-weighted imaging and magnetic resonance spectroscopy.
    Metabolic brain disease, 2017, Volume: 32, Issue:1

    Topics: Adult; Aged; Brain; Cognition; Diffusion Magnetic Resonance Imaging; Dipeptides; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychometrics

2017
[Hepatic encephalopathy. L-ornithine-L-aspartate stimulate detoxification capacity of the liver].
    MMW Fortschritte der Medizin, 2010, Jun-03, Volume: 152, Issue:22

    Topics: Ammonia; Clinical Trials as Topic; Dipeptides; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Neuropsychological Tests

2010
[Reduction of hospital stay with the use of L-ornithine L-aspartate (LOLA) in patients with hepatic encephalopathy].
    Revista de gastroenterologia de Mexico, 2010, Volume: 75, Issue:2

    Topics: Adult; Aged; Dipeptides; Female; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Length of Stay; Male; Middle Aged; Retrospective Studies

2010
Normal protein diet and L-ornithine-L-aspartate for hepatic encephalopathy.
    Acta medica Indonesiana, 2010, Volume: 42, Issue:3

    Topics: Ammonia; Dietary Proteins; Dipeptides; Dose-Response Relationship, Drug; Follow-Up Studies; Hepatic Encephalopathy; Humans; Male; Middle Aged

2010
[Optimization of treatment of patients with chronic cardiac insufficiency of the ischemic genesis and hobnail liver].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:5-6

    Topics: Aged; Anti-Infective Agents; Comorbidity; Dipeptides; Drug Combinations; Female; Heart; Heart Failure; Hepatic Encephalopathy; Humans; Liver; Male; Middle Aged; Rifamycins; Rifaximin

2011
Efficacy of oral L-ornithine L-aspartate in cirrhotic patients with hyperammonemic hepatic encephalopathy.
    Annals of hepatology, 2011, Volume: 10 Suppl 2

    Topics: Administration, Oral; Ammonia; Dipeptides; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Cirrhosis; Quality of Life; Severity of Illness Index; Treatment Outcome; Urea

2011
Hepatic encephalopathy: nomenclature, pathogenesis and treatment.
    Revista espanola de enfermedades digestivas, 2003, Volume: 95, Issue:2

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bromocriptine; Dipeptides; Dopamine Agonists; Electroencephalography; Flumazenil; GABA Modulators; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Failure, Acute; Liver Transplantation; Neomycin; Nutritional Physiological Phenomena; Practice Guidelines as Topic; Prognosis; Sodium Benzoate; Terminology as Topic; Time Factors; Zinc

2003
[Because hepatic encephalopathy is a frequent contributing factor. Patients with liver cirrhosis are poorer drivers].
    MMW Fortschritte der Medizin, 2003, Nov-20, Volume: 145, Issue:47

    Topics: Accidents, Traffic; Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis

2003
[Cirrhotic liver gives up in breaking up of ammonia. Poison for the brain].
    MMW Fortschritte der Medizin, 2004, Jan-29, Volume: 146, Issue:5

    Topics: Ammonia; Clinical Trials as Topic; Dipeptides; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Quality of Life; Self-Help Groups

2004
[Detection of subclinical and overt hepatic encephalopathy and treatment control after L-ornithine-L-aspartate medication by magnetic resonance spectroscopy ((1)H-MRS)].
    Zeitschrift fur Gastroenterologie, 2005, Volume: 43, Issue:4

    Topics: Adult; Ammonia; Brain; Choline; Combined Modality Therapy; Creatinine; Diet, Protein-Restricted; Dipeptides; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Inositol; Liver Cirrhosis; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Pilot Projects; Prospective Studies; Reference Values; Statistics as Topic

2005
Recovery from parkinson syndrome and prolonged visually evoked potentials in hepatic encephalopathy.
    Metabolic brain disease, 2005, Volume: 20, Issue:1

    Topics: Anti-Bacterial Agents; Antiparkinson Agents; Benzothiazoles; Brain; Chronic Disease; Dipeptides; Evoked Potentials, Visual; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Levodopa; Male; Middle Aged; Parkinsonian Disorders; Paromomycin; Pramipexole; Recovery of Function; Thiazoles; Treatment Outcome; Vision Disorders

2005
Hepatic encephalopathy following transjugular intrahepatic portosystemic shunt (TIPS): management with L-ornithine-L-aspartate and stent reduction.
    Metabolic brain disease, 2007, Volume: 22, Issue:1

    Topics: Aged; Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Diseases, Alcoholic; Liver Transplantation; Male; Portasystemic Shunt, Transjugular Intrahepatic; Postoperative Complications; Stents

2007
[New approach to diagnostics and correction of portohepatic hemodynamics in patients with chronic liver diseases].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2007, Issue:4

    Topics: Adult; Dipeptides; Female; Hepatic Encephalopathy; Hepatitis, Chronic; Humans; Hypertension, Portal; Liver Circulation; Male; Retrospective Studies; Treatment Outcome

2007
Contrasting effects of thioacetamide-induced liver damage on the brain uptake indices of ornithine, arginine and lysine: modulation by treatment with ornithine aspartate.
    Metabolic brain disease, 1996, Volume: 11, Issue:3

    Topics: Animals; Arginine; Blood-Brain Barrier; Brain; Chemical and Drug Induced Liver Injury; Dipeptides; Hepatic Encephalopathy; Infusions, Intravenous; Lysine; Male; Ornithine; Rats; Rats, Wistar; Thioacetamide

1996
L-ornithine-L-aspartate in experimental portal-systemic encephalopathy: therapeutic efficacy and mechanism of action.
    Metabolic brain disease, 1998, Volume: 13, Issue:2

    Topics: Ammonia; Animals; Dipeptides; Glutamic Acid; Hepatic Encephalopathy; Male; Portacaval Shunt, Surgical; Rats; Rats, Sprague-Dawley; Urea

1998
[Chronic liver diseases. Hepatic encephalopathy too frequently overlooked?].
    MMW Fortschritte der Medizin, 2000, Jun-22, Volume: 142, Issue:25

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Neomycin

2000
[In liver cirrhosis, not every "ammonia lowering drug" improves neuropsychiatric deficit].
    MMW Fortschritte der Medizin, 2001, Mar-01, Volume: 143, Issue:9

    Topics: Clinical Trials as Topic; Dipeptides; Hepatic Encephalopathy; Hyperammonemia; Neuropsychological Tests; Treatment Outcome

2001
[Chronic liver diseases. The nihilism has gone].
    MMW Fortschritte der Medizin, 2001, Dec-13, Volume: 143, Issue:51-52

    Topics: Amantadine; Antioxidants; Antiviral Agents; Chronic Disease; Dipeptides; Drug Therapy, Combination; Flumazenil; GABA Modulators; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Liver Diseases; Pentoxifylline; Phosphodiesterase Inhibitors; Prospective Studies; Protective Agents; Ribavirin; Silymarin

2001
Proton MR spectroscopy of neurometabolites in hepatic encephalopathy during L-ornithine-L-aspartate treatment--results of a pilot study.
    Metabolic brain disease, 2002, Volume: 17, Issue:2

    Topics: Aged; Brain; Creatine; Dipeptides; Female; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Pilot Projects; Predictive Value of Tests; Reproducibility of Results; Treatment Outcome

2002