Page last updated: 2024-08-22

ornithylaspartate and Cirrhosis, Liver

ornithylaspartate has been researched along with Cirrhosis, Liver in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (9.09)18.2507
2000's9 (27.27)29.6817
2010's19 (57.58)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Aliwa, B; Bourgeois, B; Horvath, A; Madl, T; Stadlbauer, V; Traub, J1
Arias, N; Hadjihambi, A; Jalan, R; Sheikh, M1
Dahale, AS; Sachdeva, S; Sharma, BC; Srivastava, S; Varakanahalli, S1
Gluud, LL; Goh, ET; Morgan, MY; Sidhu, SS; Stokes, CS; Vilstrup, H1
Abdo-Francis, JM; Alla, SN; Camacho-Aguilera, J; Higuera-de-la-Tijera, F; Jiménez-Ponce, F; Pérez-Hernández, JL; Salas-Gordillo, F; Servín-Caamaño, AI1
Butterworth, RF2
Kircheis, G; Lüth, S1
Butterworth, RF; McPhail, MJW1
Alsahhar, JS; Rahimi, RS1
Bai, M; Fan, D; Han, G; Qi, X; Yang, Z1
Kutepov, DE; Pasechnik, IN; Sal'nikov, PS; Vershinina, MG1
Manzhaliĭ, EH; Moĭseienko, VO; Nykula, TD; Solonovych, OS1
Achermann, P; Amodio, P; Angeli, P; Garrido, M; Montagnese, S; Raduazzo, D; Skorucak, J; Spinelli, G; Turco, M1
Bak-Bol, A; Cook, NA; Cox, IJ; Crossey, MM; Dhanjal, NS; Fitzpatrick, JA; Grover, VP; McPhail, MJ; Morgan, MY; Saxby, BK; Southern, L; Taylor-Robinson, SD; Waldman, AD; Williams, R; Wylezinska-Arridge, M1
Ahmad, I; Alam, A; Butt, AK; Dilshad, A; Khan, AA; Malik, K; Sarwar, S; Shafqat, F1
Ferenci, P; Gangl, A; König, F; Mittermaier, C; Peck-Radosavljevic, M; Schmid, M1
Krüger-Jansen, C; Lambert-Baumann, J; Oehler, G; Ong, JP; Younossi, ZM1
Hasan, I; Ndraha, S; Simadibrata, M1
Abbas, Z; Abid, S; Hamid, S; Islam, M; Jafri, W; Mumtaz, K; Shah, HA1
Blanco Vela, CI; Poo Ramírez, JL1
Fehérvári, I; Gerlei, Z; Görög, D; Kóbori, L; Nemes, B1
Dahl, Sv; Häussinger, D; Kircheis, G; Wettstein, M1
Gregor, M; Hass, HG; Hösl, F; Kaiser, S; Nägele, T; Seeger, U1
Chen, CH; Chen, MF; Gao, XC; Li, RC1
Bueverov, AO; Nadinskaia, MIu; Podymova, SD1
Gladisch, R; Hagmüller, E; Holm, E; Kortsik, C; Leweling, H; Staedt, U1
Berndt, H; Buchner, M; Görtelmeyer, R; Held, C; Hendricks, R; Kircheis, G; Krüger, B; Kuklinski, B; Meister, H; Nilius, R; Otto, HJ; Rink, C; Rösch, W; Stauch, S1
Koczorek, M1
Dicheva, DT; Iakovenko, EI; Lebedeva, EG; Maev, IV; V'iuchnova, ES1

Reviews

9 review(s) available for ornithylaspartate and Cirrhosis, Liver

ArticleYear
Hepatic encephalopathy: a critical current review.
    Hepatology international, 2018, Volume: 12, Issue:Suppl 1

    Topics: Albumins; Ammonia; Anti-Bacterial Agents; Bile Acids and Salts; Brain; Brain Edema; Cognitive Dysfunction; Dipeptides; Energy Metabolism; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Ornithine; Portasystemic Shunt, Surgical; Prognosis; Psychometrics; Severity of Illness Index; Synaptic Transmission

2018
L-ornithine L-aspartate for prevention and treatment of hepatic encephalopathy in people with cirrhosis.
    The Cochrane database of systematic reviews, 2018, May-15, Volume: 5

    Topics: Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Quality of Life; Randomized Controlled Trials as Topic

2018
Pharmacokinetic and Pharmacodynamic Properties of L-Ornithine L-Aspartate (LOLA) in Hepatic Encephalopathy.
    Drugs, 2019, Volume: 79, Issue:Suppl 1

    Topics: Ammonia; Animals; Brain; Dipeptides; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Muscles; Rats; Signal Transduction

2019
L-Ornithine L-Aspartate (LOLA) for Hepatic Encephalopathy in Cirrhosis: Results of Randomized Controlled Trials and Meta-Analyses.
    Drugs, 2019, Volume: 79, Issue:Suppl 1

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Meta-Analysis as Topic; Randomized Controlled Trials as Topic; Secondary Prevention; Systematic Reviews as Topic; Treatment Outcome

2019
Updates on the pathophysiology and therapeutic targets for hepatic encephalopathy.
    Current opinion in gastroenterology, 2019, Volume: 35, Issue:3

    Topics: Amino Acids, Aromatic; Amino Acids, Branched-Chain; Ammonia; Dipeptides; Fecal Microbiota Transplantation; Frailty; Gastrointestinal Agents; Gastrointestinal Microbiome; Glycerol; Hepatic Encephalopathy; Humans; Hypertension, Portal; Lactulose; Liver Cirrhosis; Ornithine; Phenylbutyrates; Polyethylene Glycols; Probiotics; Rifaximin; Trace Elements; Zinc

2019
Beneficial effects of L-ornithine L-aspartate for prevention of overt hepatic encephalopathy in patients with cirrhosis: a systematic review with meta-analysis.
    Metabolic brain disease, 2020, Volume: 35, Issue:1

    Topics: Clinical Trials as Topic; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Treatment Outcome

2020
l-ornithine-l-aspartate for hepatic encephalopathy in patients with cirrhosis: a meta-analysis of randomized controlled trials.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:5

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Randomized Controlled Trials as Topic; Treatment Outcome

2013
[Hepatic encephalopathy and liver transplantation].
    Magyar sebeszet, 2012, Volume: 65, Issue:2

    Topics: Ammonia; Anti-Infective Agents; Colon; Dipeptides; Disaccharides; End Stage Liver Disease; Evidence-Based Medicine; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Hungary; Hydrogen-Ion Concentration; Lactobacillus; Lactulose; Laxatives; Liver Cirrhosis; Liver Transplantation; Metronidazole; Neomycin; Rifamycins; Rifaximin; Severity of Illness Index; Sugar Alcohols; Systemic Inflammatory Response Syndrome; Treatment Outcome

2012
Clinical efficacy of L-ornithine-L-aspartate in the management of hepatic encephalopathy.
    Metabolic brain disease, 2002, Volume: 17, Issue:4

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Muscular Diseases; Severity of Illness Index

2002

Trials

12 trial(s) available for ornithylaspartate and Cirrhosis, Liver

ArticleYear
Secondary prophylaxis of hepatic encephalopathy in cirrhosis of liver: a double-blind randomized controlled trial of L-ornithine L-aspartate versus placebo.
    European journal of gastroenterology & hepatology, 2018, Volume: 30, Issue:8

    Topics: Adult; Ammonia; Biomarkers; Chi-Square Distribution; Dipeptides; Double-Blind Method; Female; Flicker Fusion; Hepatic Encephalopathy; Humans; India; Kaplan-Meier Estimate; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neuropsychological Tests; Odds Ratio; Psychometrics; Recurrence; Risk Factors; Secondary Prevention; Sickness Impact Profile; Tertiary Care Centers; Time Factors; Treatment Outcome

2018
Primary Prophylaxis to Prevent the Development of Hepatic Encephalopathy in Cirrhotic Patients with Acute Variceal Bleeding.
    Canadian journal of gastroenterology & hepatology, 2018, Volume: 2018

    Topics: Acute Disease; Adult; Dipeptides; Double-Blind Method; Esophageal and Gastric Varices; Female; Gastrointestinal Agents; Gastrointestinal Hemorrhage; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Male; Middle Aged; Rifaximin

2018
L-ornithine-L-aspartate infusion efficacy in hepatic encephalopathy.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2008, Volume: 18, Issue:11

    Topics: Adult; Aged; Ammonia; Cognition; Dipeptides; Female; Health Status Indicators; Hepatic Encephalopathy; Humans; Hyperammonemia; Infusions, Intravenous; Liver Cirrhosis; Male; Middle Aged; Postprandial Period

2008
A double-blind, randomized, placebo-controlled trial of intravenous L-ornithine-L-aspartate on postural control in patients with cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2010, Volume: 30, Issue:4

    Topics: Aged; Ammonia; Biopsy, Needle; Dipeptides; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Hepatic Encephalopathy; Humans; Immunohistochemistry; Infusions, Intravenous; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Pilot Projects; Postural Balance; Psychometrics; Reference Values; Risk Assessment; Sensation Disorders; Severity of Illness Index; Statistics, Nonparametric; Survival Rate; Treatment Outcome

2010
Oral L-ornithine-L-aspartate improves health-related quality of life in cirrhotic patients with hepatic encephalopathy: an open-label, prospective, multicentre observational study.
    Clinical drug investigation, 2011, Volume: 31, Issue:4

    Topics: Administration, Oral; Adult; Aged; Dipeptides; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Prospective Studies; Quality of Life

2011
The effect of L-ornithine L-aspartate and branch chain amino acids on encephalopathy and nutritional status in liver cirrhosis with malnutrition.
    Acta medica Indonesiana, 2011, Volume: 43, Issue:1

    Topics: Adult; Aged; Albumins; Amino Acids, Branched-Chain; Ammonia; Dietary Proteins; Dipeptides; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Malnutrition; Middle Aged; Nutritional Status; Young Adult

2011
Efficacy of L-ornithine-L-aspartate as an adjuvant therapy in cirrhotic patients with hepatic encephalopathy.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2011, Volume: 21, Issue:11

    Topics: Anti-Infective Agents; Dipeptides; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Agents; Glucose; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Lactulose; Length of Stay; Liver Cirrhosis; Male; Metronidazole; Middle Aged; Prospective Studies; Treatment Outcome

2011
[Therapeutic effect of L-ornithine-L-aspartate on liver cirrhosis complicated by hepatic encephalopathy].
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:6

    Topics: Dipeptides; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Cirrhosis; Male; Middle Aged

2005
[The treatment of hepatic encephalopathy with Hepa-Mertz].
    Terapevticheskii arkhiv, 1995, Volume: 67, Issue:6

    Topics: Ammonia; Biomarkers; Chronic Disease; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Psychomotor Performance; Time Factors

1995
Effects of ornithine aspartate on plasma ammonia and plasma amino acids in patients with cirrhosis. A double-blind, randomized study using a four-fold crossover design.
    Journal of hepatology, 1993, Volume: 19, Issue:3

    Topics: Adult; Amino Acids; Ammonia; Blood Glucose; Dipeptides; Double-Blind Method; Female; Humans; Insulin; Liver Cirrhosis; Male; Middle Aged; Urea

1993
Therapeutic efficacy of L-ornithine-L-aspartate infusions in patients with cirrhosis and hepatic encephalopathy: results of a placebo-controlled, double-blind study.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:6

    Topics: Adult; Aged; Ammonia; Dipeptides; Double-Blind Method; Female; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Liver Cirrhosis; Male; Mental Health; Middle Aged; Placebos; Veins

1997
[The response to combined therapy of hepatic encephalopathy in patients with hepatic cirrhosis].
    Klinicheskaia meditsina, 2002, Volume: 80, Issue:5

    Topics: Adult; Dipeptides; Drug Therapy, Combination; Female; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Male; Middle Aged

2002

Other Studies

12 other study(ies) available for ornithylaspartate and Cirrhosis, Liver

ArticleYear
Oral Intake of L-Ornithine-L-Aspartate Is Associated with Distinct Microbiome and Metabolome Changes in Cirrhosis.
    Nutrients, 2022, Feb-10, Volume: 14, Issue:4

    Topics: Dipeptides; Humans; Liver Cirrhosis; Metabolome; Microbiota; Retrospective Studies

2022
L-Ornithine L-Aspartate (LOLA) for the Treatment of Hepatic Encephalopathy in Cirrhosis: Novel Insights and Translation to the Clinic.
    Drugs, 2019, Volume: 79, Issue:Suppl 1

    Topics: Astrocytes; Dipeptides; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Cirrhosis; Translational Research, Biomedical

2019
[Comparative effectiveness of different treatment methods of liver failure].
    Khirurgiia, 2014, Issue:3

    Topics: Comparative Effectiveness Research; Dipeptides; Extracorporeal Circulation; Female; Gastrointestinal Agents; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Liver Failure; Male; Middle Aged; Monitoring, Physiologic; Plasma Exchange; Sorption Detoxification; Treatment Outcome

2014
[Pathogenesis, diagnosis and treatment of hepatic encephalopathies in patients with liver cirrhosis].
    Likars'ka sprava, 2014, Issue:11

    Topics: Adult; Aged; Ammonia; Citric Acid Cycle; Dipeptides; Event-Related Potentials, P300; Female; Hepatic Encephalopathy; Humans; Liver; Liver Cirrhosis; Male; Middle Aged; Protective Agents; Severity of Illness Index

2014
Vigilance and wake EEG architecture in simulated hyperammonaemia: a pilot study on the effects of L-Ornithine-L-Aspartate (LOLA) and caffeine.
    Metabolic brain disease, 2016, Volume: 31, Issue:4

    Topics: Adult; Brain; Caffeine; Dipeptides; Electroencephalography; Female; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Cirrhosis; Male; Middle Aged; Neuropsychological Tests; Pilot Projects; Wakefulness

2016
A longitudinal study of patients with cirrhosis treated with L-ornithine L-aspartate, examined with magnetization transfer, diffusion-weighted imaging and magnetic resonance spectroscopy.
    Metabolic brain disease, 2017, Volume: 32, Issue:1

    Topics: Adult; Aged; Brain; Cognition; Diffusion Magnetic Resonance Imaging; Dipeptides; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychometrics

2017
Efficacy of oral L-ornithine L-aspartate in cirrhotic patients with hyperammonemic hepatic encephalopathy.
    Annals of hepatology, 2011, Volume: 10 Suppl 2

    Topics: Administration, Oral; Ammonia; Dipeptides; Glutamine; Hepatic Encephalopathy; Humans; Hyperammonemia; Liver Cirrhosis; Quality of Life; Severity of Illness Index; Treatment Outcome; Urea

2011
[Because hepatic encephalopathy is a frequent contributing factor. Patients with liver cirrhosis are poorer drivers].
    MMW Fortschritte der Medizin, 2003, Nov-20, Volume: 145, Issue:47

    Topics: Accidents, Traffic; Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Liver Cirrhosis

2003
[Cirrhotic liver gives up in breaking up of ammonia. Poison for the brain].
    MMW Fortschritte der Medizin, 2004, Jan-29, Volume: 146, Issue:5

    Topics: Ammonia; Clinical Trials as Topic; Dipeptides; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Quality of Life; Self-Help Groups

2004
[Detection of subclinical and overt hepatic encephalopathy and treatment control after L-ornithine-L-aspartate medication by magnetic resonance spectroscopy ((1)H-MRS)].
    Zeitschrift fur Gastroenterologie, 2005, Volume: 43, Issue:4

    Topics: Adult; Ammonia; Brain; Choline; Combined Modality Therapy; Creatinine; Diet, Protein-Restricted; Dipeptides; Energy Metabolism; Female; Follow-Up Studies; Glutamic Acid; Glutamine; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Inositol; Liver Cirrhosis; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neuropsychological Tests; Pilot Projects; Prospective Studies; Reference Values; Statistics as Topic

2005
[Chronic liver diseases. Hepatic encephalopathy too frequently overlooked?].
    MMW Fortschritte der Medizin, 2000, Jun-22, Volume: 142, Issue:25

    Topics: Ammonia; Dipeptides; Hepatic Encephalopathy; Humans; Lactulose; Liver Cirrhosis; Neomycin

2000
[Chronic liver diseases. The nihilism has gone].
    MMW Fortschritte der Medizin, 2001, Dec-13, Volume: 143, Issue:51-52

    Topics: Amantadine; Antioxidants; Antiviral Agents; Chronic Disease; Dipeptides; Drug Therapy, Combination; Flumazenil; GABA Modulators; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Interferons; Liver Cirrhosis; Liver Diseases; Pentoxifylline; Phosphodiesterase Inhibitors; Prospective Studies; Protective Agents; Ribavirin; Silymarin

2001