ornithine and Neoplasms

ornithine has been researched along with Neoplasms in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199024 (66.67)18.7374
1990's0 (0.00)18.2507
2000's4 (11.11)29.6817
2010's4 (11.11)24.3611
2020's4 (11.11)2.80

Authors

AuthorsStudies
Gao, J; Hao, X; Li, J; Li, S; Liu, H; Qin, K; Shi, D; Wang, H; Wu, P; Wu, Z1
Buijsman, RC; de Man, J; Friesen, J; Grobben, Y; Uitdehaag, JCM; van den Hurk, H; van Groningen, J; Willemsen-Seegers, N; Zaman, GJR1
Chai, X; He, M; Li, B; Liu, S; Ma, H; Pan, J; Wang, J; Wang, Y; Zhan, J1
Frühauf, J; Gangjee, A; Hou, Z; Matherly, LH; Ning, C; O'Connor, C; Tong, N; Wallace-Povirk, A1
Bosenberg, MW; Guo, JY; Hu, ZS; Jiang, C; Lattime, E; Lu, W; Maganti, A; Mehnert, JM; Poillet-Perez, L; Rabinowitz, JD; Sharp, DW; Su, X; White, E; Xie, X; Yang, Y; Zhan, L; Zheng, H1
Cynober, L; De Bandt, JP; Ramani, D1
Aguilar-Faisal, L; Alcántara-Farfán, V; Cordero-Rodríguez, NI; Medina-Enríquez, MM; Rodríguez-Páez, L; Ruiz-Cuello, T; Trujillo-Ferrara, JG; Vargas-Ramírez, AL1
Bera, S; Ray, M; Ray, S; Wallimann, T1
Bobak, YP; Kurlishchuk, YV; Sibirny, AA; Stasyk, OV; Vynnytska, BO1
CHRISTENSEN, HN1
THOMPSON, CB1
BOIVIN, P; FAUVERT, R1
Veryard, C1
Brown, RR1
Burchenal, JH; Warrell, RP1
Burchenal, JH; Coonley, CJ; Warrell, RP1
Heby, O2
Belleville, F; Brossat, B; Metz, R; Nabet, P; Straczek, J1
Abeloff, MD; Baylin, SB; Blanc, O; Griffin, CA; Hermann, J; Luk, GD; Sjoerdsma, A; Slavik, M1
Marton, LJ; Oredsson, SM1
Bennet, LR; Buffkin, DC; Juillard, GJ; Schwabe, AD; Verma, RC; Webber, MM1
Ishiguro, I; Matsuzawa, T; Sobue, M; Sugimoto, N1
Dechelotte, P; Nitenberg, G1
Weber, G2
Inoue, H; Takeda, Y1
Canellakis, ZN; Williams-Ashman, HG1
Phang, JM1
Kingsnorth, AN1
Romijn, JC; Splinter, TA1
Kovach, JS; Svingen, PA1
Ogawa, M1
Komar, KA; Seidenfeld, J1
Seidenfeld, J1
Russell, DH1

Reviews

10 review(s) available for ornithine and Neoplasms

ArticleYear
Aliphatic polyamines in physiology and diseases.
    Clinical nutrition (Edinburgh, Scotland), 2014, Volume: 33, Issue:1

    Topics: Agmatine; Animals; Disease Models, Animal; Humans; Neoplasms; Ornithine; Putrescine; Spermidine; Spermine

2014
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship

1983
Is immune nutrition the Holy Grail for cancer patients?
    Nestle Nutrition workshop series. Clinical & performance programme, 2000, Volume: 4

    Topics: Arginine; Fatty Acids, Unsaturated; Glutamine; Hospitalization; Humans; Immunotherapy; Length of Stay; Neoplasms; Nutritional Physiological Phenomena; Nutritional Support; Ornithine; Treatment Outcome

2000
Ordered biochemical program of gene expression in cancer cells.
    Biochemistry. Biokhimiia, 2001, Volume: 66, Issue:10

    Topics: Animals; Disease Progression; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Molecular Biology; Neoplasms; Organ Specificity; Ornithine; Purines; Pyrimidines

2001
[Metabolism and function of polyamines (author's transl)].
    Seikagaku. The Journal of Japanese Biochemical Society, 1977, Volume: 49, Issue:6

    Topics: Animals; Cell Division; Chick Embryo; Humans; Isoproterenol; Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines; Rats

1977
The regulatory functions of proline and pyrroline-5-carboxylic acid.
    Current topics in cellular regulation, 1985, Volume: 25

    Topics: Amino Acids; Animals; Biological Transport; Cell Communication; Cell Cycle; Charcoal; Glutamates; Glutamic Acid; Humans; Mitosis; NADP; Neoplasms; Ornithine; Oxidation-Reduction; Phosphoribosyl Pyrophosphate; Proline; Protein Biosynthesis; Purine Nucleotides; Pyrroles; Structure-Activity Relationship

1985
The chemotherapeutic potential of polyamine antimetabolites.
    Annals of the Royal College of Surgeons of England, 1986, Volume: 68, Issue:2

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Body Weight; Cell Division; Cell Line; Child; Drug Interactions; Eflornithine; Female; Humans; Mice; Mitoguazone; Neoplasms; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Rats

1986
[Current status of clinical results of new antitumor drugs].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:2

    Topics: Aminoacridines; Amsacrine; Anthracyclines; Anthraquinones; Antibiotics, Antineoplastic; Antineoplastic Agents; Aziridines; Benzoquinones; Carboplatin; Carubicin; Cisplatin; Daunorubicin; Doxorubicin; Eflornithine; Epirubicin; Humans; Idarubicin; Mitoxantrone; Naphthacenes; Neoplasms; Organoplatinum Compounds; Ornithine; Ribavirin

1985
Ornithine decarboxylase as target of chemotherapy.
    Advances in enzyme regulation, 1985, Volume: 24

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Cloning, Molecular; DNA; Drug Resistance; Eflornithine; Humans; Mice; Neoplasms; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Biosynthesis; Subcellular Fractions

1985
The roles of the polyamines, putrescine, spermidine, and spermine in normal and malignant tissues.
    Life sciences, 1973, Dec-16, Volume: 13, Issue:12

    Topics: Animals; Carboxy-Lyases; DNA-Directed RNA Polymerases; Drug Synergism; Humans; Neoplasms; Ornithine; Polyamines; Putrescine; RNA; S-Adenosylmethionine; Spermidine; Spermine; Xenopus

1973

Trials

1 trial(s) available for ornithine and Neoplasms

ArticleYear
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship

1983

Other Studies

26 other study(ies) available for ornithine and Neoplasms

ArticleYear
A new
    Amino acids, 2023, Volume: 55, Issue:5

    Topics: Animals; Gallium Radioisotopes; Neoplasms; Ornithine; Positron-Emission Tomography; Rats; Tissue Distribution

2023
High-Throughput Fluorescence-Based Activity Assay for Arginase-1.
    SLAS discovery : advancing life sciences R & D, 2020, Volume: 25, Issue:9

    Topics: Arginase; Arginine; Enzyme Inhibitors; Fluorescence; High-Throughput Screening Assays; Humans; Neoplasms; Ornithine; T-Lymphocytes

2020
The rational discovery of multipurpose inhibitors of the ornithine decarboxylase.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:9

    Topics: A549 Cells; Animals; Antineoplastic Agents; Biocatalysis; Cell Survival; Female; High-Throughput Screening Assays; Humans; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Protein Binding; Putrescine; Xenograft Model Antitumor Assays

2020
Folate transporter dynamics and therapy with classic and tumor-targeted antifolates.
    Scientific reports, 2021, 03-18, Volume: 11, Issue:1

    Topics: Biological Transport; Cell Proliferation; Folate Receptor 1; Folic Acid; Folic Acid Antagonists; HeLa Cells; Humans; Methotrexate; Neoplasms; Ornithine; Pemetrexed; Proton-Coupled Folate Transporter; Pterins; Reduced Folate Carrier Protein

2021
Autophagy maintains tumour growth through circulating arginine.
    Nature, 2018, Volume: 563, Issue:7732

    Topics: Allografts; Animals; Arginase; Arginine; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Carcinogenesis; Cell Proliferation; Dietary Supplements; Hepatocytes; Liver; Male; Mice; Neoplasm Transplantation; Neoplasms; Ornithine

2018
N-ω-chloroacetyl-L-ornithine has in-vitro activity against cancer cell lines and in-vivo activity against ascitic and solid tumors.
    Anti-cancer drugs, 2016, Volume: 27, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ascites; Cell Line, Tumor; Cell Movement; Drug Screening Assays, Antitumor; Humans; Male; Mice, Inbred BALB C; Neoplasms; Ornithine; Toxicity Tests, Subchronic; Xenograft Model Antitumor Assays

2016
Enzymes of creatine biosynthesis, arginine and methionine metabolism in normal and malignant cells.
    The FEBS journal, 2008, Volume: 275, Issue:23

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenosylhomocysteinase; Amidinotransferases; Animals; Arginase; Arginine; Carcinoma, Ehrlich Tumor; Cell Line, Tumor; Creatine; Creatinine; Enzymes; Female; Gene Expression Regulation, Neoplastic; Guanidinoacetate N-Methyltransferase; Kidney; Liver; Membrane Transport Proteins; Methionine; Mice; Muscle, Skeletal; Neoplasms; Ornithine; Ornithine Decarboxylase; Sarcoma 180

2008
Cancer cell sensitivity to arginine deprivation in vitro is not determined by endogenous levels of arginine metabolic enzymes.
    Cell biology international, 2010, Volume: 34, Issue:11

    Topics: Arginase; Arginine; Argininosuccinate Synthase; Citrulline; Epithelial Cells; Humans; Neoplasms; Ornithine; Ornithine Carbamoyltransferase; Tumor Cells, Cultured

2010
A TRANSPORT SYSTEM SERVING FOR MONO- AND DIAMINO ACIDS.
    Proceedings of the National Academy of Sciences of the United States of America, 1964, Volume: 51

    Topics: Amino Acids; Aminobutyrates; Aminoisobutyric Acids; Arginine; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Glutamine; Glycine; Leucine; Lysine; Neoplasms; Ornithine; Phenylalanine; Proteins; Research

1964
[ROLE OF THE ARGININE-ARGINASE COMPLEX IN NORMAL AND ABNORMAL TISSUE GROWTH].
    Anales de la Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay, 1963, Volume: 48

    Topics: Arginase; Arginine; Growth; Humans; Neoplasms; Ornithine; Physiological Phenomena; Proteins; Ultraviolet Rays

1963
[COMPARATIVE VALUE OF THE DETERMINATION OF SOME SERUM ENZYME ACTIVITIES IN HEPATIC PATHOLOGY].
    La Presse medicale, 1964, Dec-19, Volume: 72

    Topics: Alanine Transaminase; Alcohol Oxidoreductases; Alcoholism; Aldehyde-Lyases; Alkaline Phosphatase; Aspartate Aminotransferases; Clinical Enzyme Tests; Fatty Liver; Hepatitis; Humans; Isocitrate Dehydrogenase; Jaundice; Jaundice, Obstructive; Leucyl Aminopeptidase; Liver Cirrhosis; Liver Neoplasms; Neoplasms; Ornithine; Ornithine Carbamoyltransferase

1964
AACR-NCI-EORTC--17th symposium: Molecular targets and cancer therapeutics. 14-18th November 2005, Philadelphia, PA, USA.
    IDrugs : the investigational drugs journal, 2006, Volume: 9, Issue:1

    Topics: Angiopoietin-2; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzodiazepinones; Clinical Trials, Phase I as Topic; ErbB Receptors; Humans; Neoplasms; Ornithine; Pterins; Pyrroles; Receptor, EphA2; Societies, Scientific

2006
Aminoaciduria resulting from cycloleucine administration in man.
    Science (New York, N.Y.), 1967, Jul-28, Volume: 157, Issue:3787

    Topics: Amino Acids; Arginine; Cystinuria; Humans; Kidney Tubules; Lysine; Neoplasms; Ornithine

1967
Sequential inhibition of polyamine synthesis. A phase I trial of DFMO (alpha-difluoromethylornithine) and methyl-GAG [methylglyoxal-bis(guanylhydrazone)].
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Drug Therapy, Combination; Eflornithine; Guanidines; Humans; Middle Aged; Mitoguazone; Neoplasms; Ornithine; Polyamines

1983
Cell cycle phase specificity and therapeutic effectiveness of polyamine synthesis inhibitors.
    Progress in clinical and biological research, 1983, Volume: 132C

    Topics: Animals; Cell Cycle; Eflornithine; Humans; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines

1983
Determination of free and total polyamines in human serum and urine by ion-pairing high-performance liquid chromatography using a radial compression module. Application to blood polyamine determination in cancer patients treated or not treated with an orn
    Journal of chromatography, 1983, Oct-14, Volume: 277

    Topics: Aged; Cadaverine; Chromatography, High Pressure Liquid; Eflornithine; Female; Fluorescence; Humans; Male; Middle Aged; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine

1983
Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1984, Volume: 2, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation; Eflornithine; Humans; Kinetics; Middle Aged; Neoplasms; Ornithine; Polyamines

1984
Potential uses of polyamine biosynthesis inhibitors in tumor therapy.
    Progress in experimental tumor research, 1984, Volume: 28

    Topics: Animals; Antineoplastic Agents; Cell Cycle; DNA Repair; Drug Therapy, Combination; Eflornithine; Humans; Mitoguazone; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Sister Chromatid Exchange

1984
Ornithine metabolism in normal subjects and patients with cancer.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1980, Volume: 21, Issue:12

    Topics: Adult; Carbon Dioxide; Decarboxylation; Female; Humans; Male; Middle Aged; Neoplasms; Ornithine; Ornithine Decarboxylase; Pregnancy; Respiration

1980
Ornithine oxoacid aminotransferase found in AH 130 ascites hepatoma cells.
    Biochimica et biophysica acta, 1982, Feb-02, Volume: 714, Issue:2

    Topics: Animals; Cell Line; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Fractional Precipitation; Humans; Hydrogen-Ion Concentration; Intestines; Ketoglutaric Acids; Kidney; Kinetics; Liver; Liver Neoplasms, Experimental; Neoplasms; Ornithine; Ornithine-Oxo-Acid Transaminase; Rats; Rats, Inbred Strains; Transaminases

1982
Proceedings: Altered biochemical pattern and metabolic regulation in cancer cells.?2Ol.
    Journal of biochemistry, 1976, Volume: 79, Issue:4

    Topics: Carbohydrate Metabolism; Cell Membrane; Cyclic AMP; DNA, Neoplasm; Genes; Glycolysis; Neoplasms; Ornithine; RNA, Neoplasm

1976
Polyamines in mammalian biology and medicine.
    Perspectives in biology and medicine, 1979,Spring, Volume: 22, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Isoelectric Point; Molecular Conformation; Neoplasms; Ornithine; Polyamines; Protein Biosynthesis; Putrescine; Semen; Sexual Maturation; Spermidine; Spermine; Structure-Activity Relationship

1979
Phase I study of alpha-difluoromethylornithine and methyl-GAG.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Antineoplastic Combined Chemotherapy Protocols; Deafness; Drug Evaluation; Eflornithine; Humans; Leukopenia; Middle Aged; Mitoguazone; Neoplasms; Ornithine; Thrombocytopenia

1986
Enhancement of the antiproliferative activity of human interferon by polyamine depletion.
    Cancer treatment reports, 1985, Volume: 69, Issue:1

    Topics: Aspirin; Cell Division; Cell Line; Doxorubicin; Drug Synergism; Eflornithine; Humans; Indomethacin; Interferon Type I; Neoplasms; Ornithine; Polyamines; Putrescine; Tumor Stem Cell Assay

1985
Chemosensitization of cultured human carcinoma cells to 1,3-bis(2-chloroethyl)-1-nitrosourea by difluoromethylornithine-induced polyamine depletion.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Carmustine; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine; Humans; Neoplasms; Ornithine; Ornithine Decarboxylase; Polyamines

1985
Effects of difluoromethylornithine on proliferation, polyamine content and plating efficiency of cultured human carcinoma cells.
    Cancer chemotherapy and pharmacology, 1985, Volume: 15, Issue:3

    Topics: Cell Division; Cell Line; Clone Cells; Eflornithine; Female; Humans; Kinetics; Neoplasms; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine

1985