ornithine has been researched along with Leukemia in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Adamson, PC; Norris, RE | 1 |
| Assaraf, YG; Ifergan, I; Jansen, G; Kaufman, Y; Rothem, L | 1 |
| Burchenal, JH; Warrell, RP | 1 |
| Alhonen-Hongisto, L; Jänne, J; Seppänen, P; Siimes, M | 1 |
| Chen, Y; Rosowsky, A; Vaidya, CM; Wright, JE | 1 |
| Assaraf, YG; Bunni, MA; Drori, S; Jansen, G; Kathmann, I; Mauritz, R; Noordhuis, P; Peters, GJ; Pinedo, HM; Priest, DG; Rosowsky, A; Schornagel, JH | 1 |
| Franco, CT; Hsieh, P; McGuire, JJ; Piper, JR | 1 |
| Chorváth, B; Forgács, A; Horáková, K; Perényi, T; Valentová, N | 1 |
| Seidenfeld, J; Williams-Ashman, HG | 1 |
| Estey, E; Freireich, EJ; Keating, MJ; Maddox, AM; McCredie, KE | 1 |
3 review(s) available for ornithine and Leukemia
| Article | Year |
|---|---|
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship | 1983 |
Use of polyamine antimetabolites in experimental tumours and in human leukemia.
Topics: Animals; Antimetabolites, Antineoplastic; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Humans; Leukemia; Mitoguazone; Neoplasms, Experimental; Ornithine; Polyamines | 1981 |
Aspects of the biochemical pharmacology of methyl glyoxal bis(guanylhydrazone).
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Carnitine; Cell Division; DNA Replication; Eflornithine; Energy Metabolism; Humans; Kinetics; Leukemia; Male; Mitochondria; Mitoguazone; Nucleic Acids; Ornithine; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Polyamines; Protein Biosynthesis; Putrescine; Virus Replication | 1986 |
1 trial(s) available for ornithine and Leukemia
| Article | Year |
|---|---|
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship | 1983 |
7 other study(ies) available for ornithine and Leukemia
| Article | Year |
|---|---|
Clinical potency of methotrexate, aminopterin, talotrexin and pemetrexed in childhood leukemias.
Topics: Aminopterin; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Child; Dose-Response Relationship, Drug; Folic Acid Antagonists; Glutamates; Guanine; Humans; Inhibitory Concentration 50; Jurkat Cells; Leukemia; Lymphoma; Methotrexate; Molecular Structure; Ornithine; Pemetrexed; Pterins | 2010 |
Coexistence of multiple mechanisms of PT523 resistance in human leukemia cells harboring 3 reduced folate carrier alleles: transcriptional silencing, inactivating mutations, and allele loss.
Topics: Alleles; Biological Transport; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression Regulation, Leukemic; Gene Silencing; Humans; Leukemia; Loss of Heterozygosity; Membrane Transport Proteins; Methotrexate; Ornithine; Pterins; Reduced Folate Carrier Protein; Response Elements; Tetrahydrofolate Dehydrogenase; Transcription Factors | 2006 |
Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate N(alpha)-(4-amino-4-deoxypteroyl)-N(delta)-hemiphthaloyl-L- ornithine (PT523) and its B-ring analogues.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Biological Transport; Carrier Proteins; Drug Interactions; Drug Screening Assays, Antitumor; Folic Acid Antagonists; Humans; Leukemia; Membrane Proteins; Membrane Transport Proteins; Methotrexate; Ornithine; Pterins; Reduced Folate Carrier Protein; Tumor Cells, Cultured | 2000 |
Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.
Topics: Biological Transport; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Folic Acid; Folic Acid Antagonists; gamma-Glutamyl Hydrolase; Glutamates; Guanine; Homeostasis; Humans; Leukemia; Methotrexate; Ornithine; Pemetrexed; Peptide Synthases; Polyglutamic Acid; Pterins; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |
Folylpolyglutamate synthetase inhibition and cytotoxic effects of methotrexate analogs containing 2,omega-diaminoalkanoic acids.
Topics: Aldehyde Oxidase; Aldehyde Oxidoreductases; Animals; Cell Line; Folic Acid Antagonists; Humans; Leukemia; Liver; Methotrexate; Ornithine; Peptide Synthases; Polyglutamic Acid; Rabbits; Rats; Structure-Activity Relationship | 1986 |
Study of metabolism and growth limitation of human leukemia cell lines.
Topics: Amino Acids; Ammonia; Cell Count; Cell Division; Cell Line; Culture Media; Glucose; Glutamine; Humans; Keto Acids; Leukemia; Ornithine; Pyruvates; Tumor Cells, Cultured | 1989 |
Phase I evaluation of intravenous difluoromethylornithine--a polyamine inhibitor.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Drug Evaluation; Eflornithine; Humans; Infusions, Parenteral; Leukemia; Leukocyte Count; Male; Middle Aged; Ornithine; Polyamines; Time Factors | 1985 |