ornithine has been researched along with Leukemia L 1210 in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (89.74) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 1 (2.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bachmann, AS; Patil, SS; Ratnapala, L; Xu, R | 1 |
| Burchenal, JH; Warrell, RP | 1 |
| Alhonen-Hongisto, L; Jänne, J; Seppänen, P | 1 |
| Chang, CC; Prakash, NJ; Sjoerdsma, A; Sunkara, PS | 1 |
| Prakash, NJ; Sunkara, PS | 1 |
| Jänne, J; Kallio, A | 1 |
| Cavanaugh, PF; Pavelic, ZP; Porter, CW | 1 |
| Alhonen-Hongisto, L; Elo, H; Fagerström, R; Jänne, J; Laine, R | 1 |
| Alhonen-Hongisto, L; Elo, H; Fagerström, R; Jänne, J; Lumme, P; Seppänen, P | 1 |
| Bartholeyns, J; Casara, P; Mamont, P | 1 |
| Bergeron, RJ; Casero, RA; Porter, CW | 1 |
| Bartholeyns, J; Koch-Weser, J | 1 |
| Alhonen-Hongisto, L; Ek-Kommonen, C; Jänne, J; Veijalainen, P | 1 |
| Diegelman, P; Kramer, D; Porter, CW; Regenass, U; Schneider, P; Stanek, J | 1 |
| Chmurzyńska, W; Grzelakowska-Sztabert, B; Manteuffel-Cymborowska, M; Peska, M | 1 |
| Grove, J; Koch-Weser, J; Prakash, NJ; Schechter, PJ | 1 |
| Abdel-Monem, MM; Newton, NE | 1 |
| Abdel-Monem, MM; Weeks, CE | 1 |
| Abdel-Monem, MM; Ho, BC; Newton, NE; Weeks, CE | 1 |
| Pegg, AE; Poulin, R; Wechter, RS | 1 |
| Bader, H; Freisheim, JH; Moran, RG; Radike-Smith, M; Rosowsky, A; Solan, VC; Wright, JE | 1 |
| Kerrigan, D; Marton, LJ; Zwelling, LA | 1 |
| Dorr, RT; Gerner, EW; Liddil, JD | 1 |
| Kramer, DL; Pera, PJ; Porter, CW; Sufrin, JR | 1 |
| Ask, A; Heby, O; Oredsson, SM; Persson, L | 1 |
| Delcamp, TJ; Freisheim, JH; Kumar, AA; Price, EM; Smith, PL; Susten, SS | 1 |
| Baccanari, DP; Delcamp, TJ; Forsch, RA; Freisheim, JH; Rosowsky, A; Solan, VC | 1 |
| Bader, H; Cucchi, CA; Freisheim, JH; Kohler, W; Moran, RG; Rosowsky, A | 1 |
| Bader, H; Forsch, RA; Freisheim, JH; Moran, RG; Rosowsky, A; Solan, VC | 1 |
| Bergeron, RJ; Cavanaugh, PF; Ganis, B; Kelly, E; Porter, CW; Stolowich, N | 1 |
| Kramer, DL; Paul, B; Porter, CW | 1 |
| Alhonen-Hongisto, L; Jänne, J; Jänne, OA; Sinervirta, R | 1 |
| Heby, O; Russell, DH | 2 |
| Burton, AF; Storr, JM | 1 |
| Johansson, JG; Skinner, WA | 1 |
| Heby, O; Russell, DH; Sauter, S | 1 |
| Russell, DH | 1 |
| Levy, CC; Russell, DH | 1 |
1 review(s) available for ornithine and Leukemia L 1210
| Article | Year |
|---|---|
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship | 1983 |
1 trial(s) available for ornithine and Leukemia L 1210
| Article | Year |
|---|---|
Methylglyoxal-bis(guanylhydrazone) (Methyl-GAG): current status and future prospects.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Colonic Neoplasms; Diarrhea; Dose-Response Relationship, Drug; Drug Eruptions; Drug Therapy, Combination; Eflornithine; Esophageal Neoplasms; Guanidines; Head and Neck Neoplasms; Humans; Kidney Neoplasms; Leukemia; Leukemia L1210; Lung Neoplasms; Mice; Mitoguazone; Muscular Diseases; Nausea; Neoplasms; Ornithine; Polyamines; Stilbamidines; Structure-Activity Relationship | 1983 |
38 other study(ies) available for ornithine and Leukemia L 1210
| Article | Year |
|---|---|
Inhibitory effects of phaseolotoxin on proliferation of leukemia cells HL-60, K-562 and L1210 and pancreatic cells RIN-m5F.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line, Tumor; Enzyme Inhibitors; Exotoxins; Female; HL-60 Cells; Humans; Insulinoma; K562 Cells; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Pancreatic Neoplasms; Rats | 2004 |
Combined use of 2-difluoromethylornithine and methylglyoxal bis(guanylhydrazone) in normal and leukemia-bearing mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Drug Therapy, Combination; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mice, Inbred DBA; Mitoguazone; Ornithine; Spleen; Time Factors; Tissue Distribution | 1983 |
Cytotoxicity of methylglyoxal bis(guanylhydrazone) in combination with alpha-difluoromethylornithine against HeLa cells and mouse L1210 leukemia.
Topics: Animals; Antineoplastic Agents; Cell Survival; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Guanidines; HeLa Cells; Humans; Leukemia L1210; Mice; Mice, Inbred Strains; Mitoguazone; Neoplasm Transplantation; Ornithine; Polyamines | 1983 |
Combination chemotherapy involving alpha-difluoromethylornithine and 1-beta-D-arabinofuranosylcytosine in murine L1210 leukemia.
Topics: Animals; Body Weight; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cytarabine; Drug Therapy, Combination; Eflornithine; Erythrocyte Count; Female; Leukemia L1210; Leukocyte Count; Longevity; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Ornithine; Polyamines | 1983 |
Role of diamine oxidase during the treatment of tumour-bearing mice with combinations of polyamine anti-metabolites.
Topics: Amine Oxidase (Copper-Containing); Animals; Antineoplastic Agents; Drug Therapy, Combination; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mice, Inbred DBA; Mitoguazone; Ornithine; Polyamines | 1983 |
Enhancement of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced cytotoxicity and DNA damage by alpha-difluoromethylornithine in L1210 leukemia cells.
Topics: Animals; Carmustine; Cell Survival; DNA, Neoplasm; Drug Synergism; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Putrescine; Spermidine; Spermine | 1984 |
Different efflux rates may determine the cellular accumulation of various bis(guanylhydrazones).
Topics: Animals; Cells, Cultured; Eflornithine; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Spermidine; Time Factors | 1984 |
Glyoxal bis(guanylhydrazone) as an inhibitor of polyamine biosynthesis in tumour cells.
Topics: Adenosylmethionine Decarboxylase; Amine Oxidase (Copper-Containing); Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mitoguazone; Neoplasm Proteins; Ornithine; Polyamines | 1984 |
Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents.
Topics: Alkynes; Animals; Antineoplastic Agents; Diamines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eflornithine; Female; Leukemia L1210; Leukemia P388; Liver Neoplasms, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred BUF | 1984 |
Treatment with alpha-difluoromethylornithine plus a spermidine analog leads to spermine depletion and growth inhibition in cultured L1210 leukemia cells.
Topics: Animals; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Eflornithine; Leukemia L1210; Mice; Ornithine; Spermidine; Spermine | 1984 |
Effects of alpha-difluoromethylornithine alone and combined with adriamycin or vindesine on L1210 leukemia in mice, EMT6 solid tumors in mice, and solid tumors induced by injection of hepatoma tissue culture cells in rats.
Topics: Animals; Doxorubicin; Drug Therapy, Combination; Eflornithine; Female; Leukemia L1210; Liver Neoplasms, Experimental; Male; Mice; Neoplasms, Experimental; Ornithine; Rats; Vinblastine; Vindesine | 1981 |
Polyamines in mycoplasmas and in mycoplasma-infected tumour cells.
Topics: Animals; Carboxy-Lyases; Carcinoma, Ehrlich Tumor; Cattle; Cells, Cultured; Eflornithine; Leukemia L1210; Mycoplasma; Ornithine; Ornithine Decarboxylase; Polyamines; Rats | 1982 |
Use of 4-fluoro-L-ornithine to monitor metabolic flux through the polyamine biosynthetic pathway.
Topics: Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Cell Division; Cell Membrane Permeability; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Humans; Kinetics; Leukemia L1210; Melanoma; Mice; Ornithine; Ornithine Decarboxylase; Spermidine; Spermine; Tumor Cells, Cultured | 1995 |
Tumour effect on arginine/ornithine metabolic relationship in hypertrophic mouse kidney.
Topics: Animals; Arginase; Arginine; Carcinoma, Ehrlich Tumor; Female; Hyperplasia; Kidney; Leukemia L1210; Mice; Mice, Inbred DBA; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Testosterone | 1997 |
Effect of alpha-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on L1210 leukemia in mice.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Spleen | 1978 |
Inhibitors of polyamine biosynthesis. 4. Effects of alpha-methyl-(+/-)-ornithine and methylglyoxal bis(guanylhydrazone) on growth and polyamine content of L1210 leukemic cells of mice.
Topics: Animals; Cell Division; Cells, Cultured; DNA, Neoplasm; Guanidines; Leukemia L1210; Mice; Mitoguazone; Ornithine; Ornithine Decarboxylase; Polyamines; Putrescine; Spermidine; Spermine | 1977 |
Inhibitors of polyamine biosynthesis V: In vivo effects of alpha-methyl-(+/-)-ornithine and alpha-methyl-(+/-)-ornithine tert-butyl ester.
Topics: Animals; Depression, Chemical; Leukemia L1210; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Ornithine; Polyamines; Spleen | 1977 |
Potential inhibitors of polyamine biosynthesis. 2. alpha-Alkyl- and benzyl-(+/-)-ornithine.
Topics: Animals; Benzyl Compounds; Chromatography, Thin Layer; Depression, Chemical; Leukemia L1210; Liver; Male; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Polyamines; Prostate; Rats; Spleen; Structure-Activity Relationship | 1975 |
An early enlargement of the putrescine pool is required for growth in L1210 mouse leukemia cells under hypoosmotic stress.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Division; Enzyme Induction; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Osmolar Concentration; Polyamines; Putrescine; Tumor Cells, Cultured | 1991 |
Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.
Topics: Aminobutyrates; Aminopterin; Animals; beta-Alanine; Cell Division; Folic Acid Antagonists; Glutamates; Glutamic Acid; Kinetics; Leukemia L1210; Methotrexate; Mice; Molecular Weight; Ornithine; Peptide Synthases | 1986 |
Effect of difluoromethylornithine, an inhibitor of polyamine biosynthesis, on the topoisomerase II-mediated DNA scission produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide in L1210 murine leukemia cells.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Agents; DNA Topoisomerases, Type I; DNA, Neoplasm; Eflornithine; Intercalating Agents; Leukemia L1210; Mice; Nucleic Acid Conformation; Ornithine; Polyamines | 1985 |
Modulation of etoposide cytotoxicity and DNA strand scission in L1210 and 8226 cells by polyamines.
Topics: Animals; Cell Survival; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Eflornithine; Etoposide; Humans; Leukemia L1210; Mice; Multiple Myeloma; Nucleic Acid Conformation; Ornithine; Podophyllotoxin; Polyamines; Putrescine | 1986 |
Comparison of the biological effects of four irreversible inhibitors of ornithine decarboxylase in two murine lymphocytic leukemia cell lines.
Topics: Alkynes; Animals; Biological Transport; Cell Cycle; Cell Survival; Diamines; Eflornithine; Leukemia L1210; Leukemia L5178; Leukemia, Lymphoid; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine | 1986 |
Synergistic antileukemic effect of two polyamine synthesis inhibitors. Host survival and cell-cycle kinetic analysis.
Topics: Adenosylmethionine Decarboxylase; Animals; Cell Cycle; Drug Synergism; Eflornithine; Leukemia L1210; Male; Mice; Mice, Inbred Strains; Mitoguazone; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines | 1986 |
Analogues of folate antagonists as affinity and fluorescent probes of dihydrofolate reductase structure and function.
Topics: Affinity Labels; Animals; Folic Acid; Leukemia L1210; Lysine; Methotrexate; Mice; Ornithine; Tetrahydrofolate Dehydrogenase; X-Ray Diffraction | 1986 |
Methotrexate analogues. 30. Dihydrofolate reductase inhibition and in vitro tumor cell growth inhibition by N epsilon-(haloacetyl)-L-lysine and N delta-(haloacetyl)-L-ornithine analogues and an acivicin analogue of methotrexate.
Topics: Acetates; Animals; Candida albicans; Chemical Phenomena; Chemistry; Folic Acid Antagonists; Isoxazoles; Leukemia L1210; Lysine; Methotrexate; Mice; NADP; Ornithine; Protein Conformation; Spectrophotometry | 1987 |
Methotrexate analogues. 33. N delta-acyl-N alpha-(4-amino-4-deoxypteroyl)-L-ornithine derivatives: synthesis and in vitro antitumor activity.
Topics: Aminopterin; Animals; Cell Division; Chemical Phenomena; Chemistry; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L1210; Methotrexate; Mice; Neoplasms, Experimental; Ornithine; Peptide Synthases; Pterins; Structure-Activity Relationship; Tumor Cells, Cultured | 1988 |
Synthesis and biologic activity of new side-chain-altered methotrexate and aminopterin analogs with dual inhibitory action against dihydrofolate reductase and folylpolyglutamate synthetase.
Topics: Aminobutyrates; Aminopterin; Animals; Cell Division; Folic Acid Antagonists; Growth Inhibitors; Leukemia L1210; Liver; Methotrexate; Mice; Ornithine; Peptide Synthases; Structure-Activity Relationship | 1987 |
Biological properties of N4- and N1,N8-spermidine derivatives in cultured L1210 leukemia cells.
Topics: Animals; Cells, Cultured; Eflornithine; Kinetics; Leukemia L1210; Mice; Ornithine; Polyamines; Spermidine; Structure-Activity Relationship | 1985 |
Effect of pretreatment with alpha-difluoromethylornithine on the selectivity of methylglyoxal bis(guanylhydrazone) for tumor tissue in L1210 leukemic mice.
Topics: Animals; Carbon Radioisotopes; Drug Therapy, Combination; Eflornithine; Female; Guanidines; Leukemia L1210; Mice; Mice, Inbred DBA; Mitoguazone; Ornithine | 1985 |
Gene expression of ornithine decarboxylase in L1210 leukaemia cells exposed to DL-2-difluoromethylornithine in the presence of cadaverine.
Topics: Animals; Cadaverine; Cells, Cultured; Diamines; DNA, Neoplasm; Eflornithine; Gene Amplification; Gene Expression Regulation; Leukemia L1210; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; RNA, Messenger | 1985 |
Depression of polyamine synthesis in L1210 leukemic mice during treatment with a potent antileukemic agent, 5-azacytidine.
Topics: Animals; Antineoplastic Agents; Azacitidine; Carboxy-Lyases; Cytidine; Depression, Chemical; Enzyme Repression; Injections, Intraperitoneal; Leukemia L1210; Liver; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Organ Size; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spleen; Triazines | 1973 |
The effects of arginine deficiency on lymphoma cells.
Topics: Animals; Arginase; Arginine; Carbon Radioisotopes; Cell Count; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Leucine; Leukemia L1210; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Ornithine; Succinates; Thymidine; Tritium; Uridine | 1974 |
Ornithine analogs as potential ornithine decarboxylase inhibitors 1. N-Substituted ornithine derivatives.
Topics: Animals; Carboxy-Lyases; Escherichia coli; Klebsiella; Leukemia L1210; Microbial Sensitivity Tests; Micrococcus; Mitosporic Fungi; Ornithine; Penicillium; Saccharomyces cerevisiae; Serratia marcescens; Staphylococcus | 1972 |
Stimulation of ornithine decarboxylase activity and inhibition of S-adenosyl-L-methionine decarboxylase activity in leukaemic mice by methylglyoxal bis(guanylhydrazone).
Topics: Adenosine; Amidines; Animals; Carboxy-Lyases; Depression, Chemical; Glyoxal; Hydrazones; Leukemia L1210; Male; Methionine; Mice; Ornithine; Polyamines; S-Adenosylmethionine; Spermidine; Stimulation, Chemical | 1973 |
Effects of methylglyoxal-bis(guanylhydrazone) on polyamine metabolism in spleens of mice with disseminated L1210 lymphoid leukemia.
Topics: Amidines; Animals; Antineoplastic Agents; Carboxy-Lyases; Glyoxal; Hydrazones; Leukemia L1210; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Ornithine; Polyamines; Putrescine; S-Adenosylmethionine; Spermidine; Spermine; Spleen; Time Factors | 1974 |
Effects of methotrexate and cytosine arabinoside on polyamine metabolism in a mouse L1210 leukemia.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cytarabine; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Spleen | 1972 |
Polyamine accumulation and biosynthesis in a mouse L1210 leukemia.
Topics: Amines; Animals; Ascitic Fluid; Butylamines; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Leukemia L1210; Methionine; Mice; Ornithine; Spermine; Transferases | 1971 |