orlistat and Fistula

We describe two innovative ideas in the treatment of iatrogenic chyle leak. The first is the early use of a pancreatic lipase inhibitor (Orlistat) to reduce fat absorption and chyle production, with consequent faster fistula healing. The second is the treatment of these patients at home in the community by district nurses backed by the hospital staff. This domiciliary approach has a positive psychological effect on the patient, permits the patient to take responsibility for their treatment, and reduces hospital length of stay minimising patient exposure to nosocomial infections.

Topics: Attitude to Health; Chyle; Diet, Fat-Restricted; Drainage; Enzyme Inhibitors; Fistula; Home Care Services; Humans; Iatrogenic Disease; Lactones; Length of Stay; Lipase; Lymphatic Diseases; Orlistat; Self Care; Thoracic Duct; Wound Healing