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organophosphonates and Viral Diseases

organophosphonates has been researched along with Viral Diseases in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's7 (33.33)18.2507
2000's4 (19.05)29.6817
2010's9 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrei, G; Brisse, E; Imbrechts, M; Matthys, P; Mitera, T; Snoeck, R; Vandenhaute, J; Wouters, CH1
Arnold, E; Balzarini, J; Das, K; Dehaen, W; Ford, A; John, J; Maguire, A; Maguire, NM1
Griffiths, PD; Kadambari, S; Sharland, M1
De Clercq, E5
Jasko, MV; Kleymenova, AA; Kochetkov, SN; Kukhanova, MK; Solyev, PN1
Berger, A; Christopeit, M; Hauf, E; Hentrich, M; Heussel, CP; Kalkreuth, J; Klein, M; Kochanek, M; Lehners, N; Mayer, K; Penack, O; Rieger, C; Schalk, E; Silling, G; Vehreschild, M; von Lilienfeld-Toal, M; Weber, T; Wolf, HH1
An, J; Du, C; Gao, JL; Jiang, Y; Li, M; Ma, H; Wang, X; Zhang, L1
Hostetler, KY1
Holý, A; Krecmerová, M; Masojídková, M1
Andrei, G; Balzarini, J; Hocková, D; Holý, A; Snoeck, R1
Eksborg, S1
Cundy, KC; Hitchcock, MJ; Lee, WA; Li, ZH1
Bidgood, AM; Cundy, KC; Griffin, L; Lee, WA; Lynch, G; Shaw, JP1
Keating, MR1
Belakhov, VV; Grinberg, GE; Ionin, BI; Levina, AA; Rachkovskaia, LA; Shatik, LI; Shenin, IuD; Shtil'bans, EB; Zaĭtseva, MB1
Inglot, AD; Kochman, M; Mastalerz, P; Pelczarska, A1

Reviews

8 review(s) available for organophosphonates and Viral Diseases

ArticleYear
Alpha-carboxynucleoside phosphonates: direct-acting inhibitors of viral DNA polymerases.
    Future medicinal chemistry, 2019, Volume: 11, Issue:2

    Topics: Animals; Antiviral Agents; DNA-Directed DNA Polymerase; Drug Discovery; Exodeoxyribonucleases; Herpes Simplex; Humans; Models, Molecular; Nucleic Acid Synthesis Inhibitors; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Viral Proteins; Virus Diseases; Viruses

2019
The novel antiviral pipeline to treat severe neonatal viral infections.
    The Pediatric infectious disease journal, 2013, Volume: 32, Issue:6

    Topics: Antiviral Agents; Drug Discovery; Enzyme Inhibitors; Humans; Infant, Newborn; Organophosphonates; Virus Diseases

2013
The Holý Trinity: the acyclic nucleoside phosphonates.
    Advances in pharmacology (San Diego, Calif.), 2013, Volume: 67

    Topics: Adenine; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Humans; Nucleosides; Organophosphonates; Prodrugs; Tenofovir; Virus Diseases

2013
Community acquired respiratory virus infections in cancer patients-Guideline on diagnosis and management by the Infectious Diseases Working Party of the German Society for haematology and Medical Oncology.
    European journal of cancer (Oxford, England : 1990), 2016, Volume: 67

    Topics: Adenovirus Infections, Human; Antiviral Agents; Cidofovir; Community-Acquired Infections; Cytosine; Germany; Hand Hygiene; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Influenza, Human; Lung; Masks; Medical Oncology; Metapneumovirus; Neoplasms; Neuraminidase; Nucleic Acid Amplification Techniques; Organophosphonates; Oseltamivir; Paramyxoviridae Infections; Patient Isolation; Pneumonia, Viral; Respiratory Syncytial Virus Infections; Respiratory Tract Infections; Ribavirin; Tomography, X-Ray Computed; Virus Diseases

2016
The pharmacokinetics of antiviral therapy in paediatric patients.
    Herpes : the journal of the IHMF, 2003, Volume: 10, Issue:3

    Topics: 2-Aminopurine; Acyclovir; Antiviral Agents; Child; Child, Hospitalized; Cidofovir; Cytosine; Famciclovir; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Virus Diseases

2003
The discovery of antiviral agents: ten different compounds, ten different stories.
    Medicinal research reviews, 2008, Volume: 28, Issue:6

    Topics: Acyclovir; Adenine; Antiviral Agents; Benzodiazepines; Benzylamines; Cidofovir; Cyclams; Cytosine; Heterocyclic Compounds; Humans; Imidazoles; Nucleosides; Organophosphonates; Tenofovir; Valacyclovir; Valine; Virus Diseases

2008
Antiviral agents for non-human immunodeficiency virus infections.
    Mayo Clinic proceedings, 1999, Volume: 74, Issue:12

    Topics: 2-Aminopurine; Acetamides; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drugs, Investigational; Enzyme Inhibitors; Famciclovir; Foscarnet; Ganciclovir; Guanidines; Guanine; Humans; Interferons; Lamivudine; Neuraminidase; Organophosphonates; Organophosphorus Compounds; Oseltamivir; Pyrans; Ribavirin; Sialic Acids; Valacyclovir; Valine; Virus Diseases; Zanamivir

1999
Therapeutic potential of phosphonylmethoxyalkylpurines and -pyrimidines as antiviral agents.
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:7

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Purines; Pyrimidines; Retroviridae Infections; Virus Diseases

1990

Trials

1 trial(s) available for organophosphonates and Viral Diseases

ArticleYear
Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: current state of the art.
    Antiviral research, 2009, Volume: 82, Issue:2

    Topics: Animals; Antiviral Agents; Drug Design; Humans; Organophosphonates; Prodrugs; Structure-Activity Relationship; Virus Diseases; Viruses

2009

Other Studies

12 other study(ies) available for organophosphonates and Viral Diseases

ArticleYear
Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis.
    Virology journal, 2017, 12-19, Volume: 14, Issue:1

    Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Dexamethasone; Disease Models, Animal; Humans; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Lymphohistiocytosis, Hemophagocytic; Mice; Mice, Inbred BALB C; Mice, Knockout; Muromegalovirus; Organophosphonates; T-Lymphocytes; Toll-Like Receptor 3; Toll-Like Receptor 9; Virus Diseases; Virus Replication

2017
Versatile synthesis of oxime-containing acyclic nucleoside phosphonates--synthetic solutions and antiviral activity.
    Organic & biomolecular chemistry, 2015, Nov-28, Volume: 13, Issue:44

    Topics: Antiviral Agents; Humans; Nucleosides; Organophosphonates; Oximes; Virus Diseases; Viruses

2015
A novel pretreatment method combining sealing technique with direct injection technique applied for improving biosafety.
    Bioanalysis, 2017, Volume: 9, Issue:2

    Topics: Adenine; Antiviral Agents; Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Humans; Limit of Detection; Organophosphonates; Tenofovir; Ultrafiltration; Virus Diseases

2017
Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytosine; Humans; Nucleosides; Organophosphonates; Vero Cells; Virus Diseases; Viruses

2010
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.
    Bioorganic & medicinal chemistry, 2011, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Herpes Simplex; HIV; HIV Infections; Humans; Mice; Nucleosides; Organophosphonates; Simplexvirus; Structure-Activity Relationship; Vaccinia; Vaccinia virus; Virus Diseases; Viruses

2011
Acyclic nucleoside phosphonates: past, present and future. Bridging chemistry to HIV, HBV, HCV, HPV, adeno-, herpes-, and poxvirus infections: the phosphonate bridge.
    Biochemical pharmacology, 2007, Apr-01, Volume: 73, Issue:7

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Hepacivirus; Hepatitis B virus; HIV; Humans; Organophosphonates; Papillomaviridae; Poxviridae; Tenofovir; Virus Diseases; Viruses

2007
Therapeutic potential of Cidofovir (HPMPC, Vistide) for the treatment of DNA virus (i.e. herpes-, papova-, pox- and adenovirus) infections.
    Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1996, Volume: 58, Issue:1

    Topics: Animals; Antiviral Agents; Base Sequence; Cattle; Cidofovir; Clinical Trials as Topic; Cytosine; DNA Viruses; DNA-Directed DNA Polymerase; Half-Life; Humans; Molecular Sequence Data; Organophosphonates; Organophosphorus Compounds; Point Mutation; Virus Diseases; Virus Replication

1996
Pharmacokinetics of cidofovir in monkeys. Evidence for a prolonged elimination phase representing phosphorylated drug.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:7

    Topics: Administration, Cutaneous; Administration, Oral; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Chlorocebus aethiops; Cidofovir; Cytosine; Injections, Intravenous; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Probenecid; Virus Diseases

1996
Pharmacokinetics, bioavailability, metabolism, and tissue distribution of cidofovir (HPMPC) and cyclic HPMPC in rats.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:7

    Topics: Administration, Cutaneous; Animals; Antiviral Agents; Biological Availability; Carbon Radioisotopes; Cidofovir; Cytosine; Female; Injections, Intravenous; Male; Organophosphonates; Organophosphorus Compounds; Prodrugs; Rats; Rats, Sprague-Dawley; Tissue Distribution; Virus Diseases

1996
Drugs for non-HIV viral infections.
    The Medical letter on drugs and therapeutics, 1997, Aug-01, Volume: 39, Issue:1006

    Topics: 2-Aminopurine; Abnormalities, Drug-Induced; Acyclovir; Amantadine; Antiviral Agents; Cidofovir; Contraindications; Cytosine; Drug Resistance, Microbial; Eye Infections, Viral; Famciclovir; Foscarnet; Ganciclovir; Guanine; Humans; Interferon-alpha; Kidney Diseases; Lamivudine; Organophosphonates; Organophosphorus Compounds; Prodrugs; Ribavirin; Rimantadine; Trifluridine; Valacyclovir; Valine; Virus Diseases

1997
[Synthesis and biological activity of aminophenylphosphonic derivatives of levorin].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1990, Volume: 35, Issue:8

    Topics: Aldehydes; Amines; Animals; Candicidin; Disease Models, Animal; Fungi; In Vitro Techniques; Male; Mice; Mycoses; Organophosphonates; Virus Diseases; Viruses

1990
Peculiarities of the antiviral action of dibenzylphosphinic acid.
    Acta virologica, 1967, Volume: 11, Issue:3

    Topics: Animals; Antiviral Agents; Culture Techniques; Encephalomyocarditis virus; Guinea Pigs; Mice; Organophosphonates; Phosphinic Acids; Rabbits; RNA, Viral; Virus Cultivation; Virus Diseases

1967