organophosphonates has been researched along with Smallpox in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (52.78) | 29.6817 |
| 2010's | 14 (38.89) | 24.3611 |
| 2020's | 3 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Buller, RM; D'Angelo, J; George, SL; Jensen, A; Lantto, J; Nielsen, H; Parker, S; Prichard, M; Smee, DF | 1 |
| Bensman, T; Birnkrant, D; Cao, Y; Chan-Tack, K; Choi, SY; Donaldson, E; Ghantous, H; Harrington, P; McMillan, D; Myers, L; O'Rear, J; Seaton, M; Struble, K; Valappil, T | 1 |
| Delaune, D; Iseni, F | 1 |
| Brundage, T; Dunn, JA; Foster, SA; Gainey, MR; Grossi, IM; Khouri, JM; Krile, RT | 1 |
| Foster, SA; Lanier, R; Parker, S | 1 |
| Damon, IK; Foster, S; Gates, I; Lanier, ER; Li, Y; Olson, VA; Smith, SK; Trost, LC | 1 |
| de Alencastro, RB; de Souza, FR; França, TC; Gonçalves, AS; Guimarães, AP; Oliveira, AA; Ramalho, TC | 1 |
| Foster, SA; Godin, SJ; Keilholz, L; Khouri, J; Long, J; Rose, ML; Trost, LC | 1 |
| Buller, RM; Crump, R; Korom, M; Parker, S | 1 |
| Brundage, T; Chittick, G; Morrison, M; Nichols, WG | 1 |
| Adams, MM; Foster, S; Lampert, B; Moyer, RW; Painter, G; Rice, AD; Robertson, A | 1 |
| Adams, MM; Burrage, AM; Foster, S; Gray, SA; Lampert, B; Lanier, R; Lindsey, SF; Manning, BR; Moyer, RW; Painter, G; Rice, AD; Robertson, A; Smith, AJ; Swetnam, D; Wallace, G | 1 |
| Hayden, EC | 1 |
| Vere Hodge, A | 1 |
| Chen, NG; Foster, S; Hartzler, H; Hembrador, E; Hruby, D; Jordan, R; Lanier, R; Mark Buller, R; Painter, G; Painter, W; Parker, S; Sagartz, JE; Schriewer, J | 1 |
| Arndt, W; Damon, IK; Denzler, KL; Jacobs, BL; Langland, JO; Mitnik, C; Olson, VA; Rochon, Y; Waters, R; White, S | 1 |
| McConnell, J | 1 |
| Eckerman, NL; Roos, KL | 1 |
| Elgh, F; Tegnell, A; Wahren, B | 1 |
| De Clercq, E; Neyts, J | 1 |
| Sidwell, RW; Smee, DF | 1 |
| Blauvelt, A; Sanchez, S; Toro, JR; Turiansky, G | 1 |
| Check, E | 2 |
| Blair, DC; Guharoy, R; Krenzelok, EP; Noviasky, JA; Panzik, R | 1 |
| Bray, M; Roy, CJ | 1 |
| Shinzato, T | 1 |
| Garrison, A; Goff, A; Lawler, J; Mucker, E; Paragas, J; Twenhafel, N | 1 |
| Adams, MM; Moyer, RW; Rice, AD | 1 |
| Bray, M; Huggins, JW; Kefauver, D; Martinez, M; Smee, DF; Thompson, E | 1 |
| Cohen, J | 1 |
| Bradbury, J | 1 |
| Evans, M; Ridings, H | 1 |
| Morris, K | 1 |
11 review(s) available for organophosphonates and Smallpox
| Article | Year |
|---|---|
Benefit-risk assessment for brincidofovir for the treatment of smallpox: U.S. Food and Drug Administration's Evaluation.
Topics: Animals; Antiviral Agents; Cytosine; Disease Eradication; Disease Models, Animal; Drug Approval; Humans; Organophosphonates; Risk Assessment; Smallpox; Treatment Outcome; United States; United States Food and Drug Administration | 2021 |
Drug Development against Smallpox: Present and Future.
Topics: Animals; Antiviral Agents; Benzamides; Biological Warfare Agents; Biomedical Research; Cytosine; Disease Models, Animal; Drug Discovery; Isoindoles; Organophosphonates; Smallpox; Variola virus | 2020 |
Efficacy of CMX001 as a prophylactic and presymptomatic antiviral agent in New Zealand white rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.
Topics: Animals; Antiviral Agents; Bioterrorism; Cytosine; Disease Models, Animal; Disease Transmission, Infectious; Humans; Mpox (monkeypox); Organophosphonates; Rabbits; Smallpox; Smallpox Vaccine; Vaccinia virus | 2011 |
Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.
Topics: Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Disease Transmission, Infectious; Dose-Response Relationship, Drug; Humans; Mpox (monkeypox); Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia virus | 2011 |
Therapy and short-term prophylaxis of poxvirus infections: historical background and perspectives.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; History, 20th Century; Humans; Organophosphonates; Organophosphorus Compounds; Poxviridae Infections; Smallpox; Time Factors; Vaccinia | 2003 |
A review of compounds exhibiting anti-orthopoxvirus activity in animal models.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Disease Models, Animal; Humans; Mice; Mice, SCID; Nucleosides; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Poxviridae Infections; Rabbits; Smallpox; Thiosemicarbazones | 2003 |
Topical cidofovir for the treatment of dermatologic conditions: verruca, condyloma, intraepithelial neoplasia, herpes simplex and its potential use in smallpox.
Topics: Administration, Cutaneous; Administration, Topical; Antiviral Agents; Carcinoma in Situ; Carcinoma, Squamous Cell; Cidofovir; Condylomata Acuminata; Cytosine; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Infectious; Skin Neoplasms; Smallpox; Warts | 2003 |
Smallpox: clinical features, prevention, and management.
Topics: Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Female; Humans; Infant; Male; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine | 2004 |
Antiviral prophylaxis of smallpox.
Topics: Antiviral Agents; Cidofovir; Combined Modality Therapy; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; Vaccination | 2004 |
[Smallpox].
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Diagnosis, Differential; Humans; Organophosphonates; Polymerase Chain Reaction; Smallpox; Smallpox Vaccine; Vaccines, Attenuated; Variola virus | 2004 |
Understanding the threat of smallpox.
Topics: Bioterrorism; Cidofovir; Cytosine; Diagnosis, Differential; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States | 2002 |
1 trial(s) available for organophosphonates and Smallpox
| Article | Year |
|---|---|
Short-term clinical safety profile of brincidofovir: A favorable benefit-risk proposition in the treatment of smallpox.
Topics: Adenoviridae; Adolescent; Adult; Animals; Antiviral Agents; Cytomegalovirus; Cytosine; Disease Models, Animal; Double-Blind Method; Drug Administration Schedule; Humans; Middle Aged; Organophosphonates; Orthopoxvirus; Safety; Smallpox; Young Adult | 2017 |
24 other study(ies) available for organophosphonates and Smallpox
| Article | Year |
|---|---|
A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge.
Topics: Animals; Antiviral Agents; Benzamides; Cell Line; Chlorocebus aethiops; Cytosine; Female; Humans; Immunoglobulins; Isoindoles; Mice; Mice, Inbred BALB C; Organophosphonates; Orthopoxvirus; Smallpox; Smallpox Vaccine; Vaccines, DNA; Vaccinia | 2021 |
Efficacy of delayed brincidofovir treatment against a lethal rabbitpox virus challenge in New Zealand White rabbits.
Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Body Temperature; Body Weight; Cytosine; Disease Models, Animal; Double-Blind Method; Organophosphonates; Poxviridae Infections; Rabbits; Smallpox; Survival Rate; Treatment Outcome; Vaccination; Vaccinia; Vaccinia virus; Variola virus; Viral Load | 2017 |
The Role of Brincidofovir in Preparation for a Potential Smallpox Outbreak.
Topics: Animals; Antiviral Agents; Benzamides; Biological Warfare Agents; Cytosine; Databases, Pharmaceutical; Disease Outbreaks; Drug Resistance, Viral; Drug Therapy, Combination; Humans; Isoindoles; Models, Animal; Organophosphonates; Smallpox; Variola virus | 2017 |
The spectre of smallpox lingers.
Topics: Animals; Benzamides; Cytosine; Disease Eradication; Disease Models, Animal; Disease Reservoirs; Drug Approval; Female; History, 20th Century; History, 21st Century; Humans; Isoindoles; Organophosphonates; Rabbits; Smallpox; Smallpox Vaccine; Synthetic Biology; United States; United States Food and Drug Administration | 2018 |
In vitro efficacy of brincidofovir against variola virus.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Organophosphonates; Smallpox; Variola virus | 2014 |
Design of inhibitors of thymidylate kinase from Variola virus as new selective drugs against smallpox.
Topics: Acyclovir; Antiviral Agents; Catalytic Domain; Cidofovir; Cytosine; Drug Design; Humans; Kinetics; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Mutation; Nucleoside-Phosphate Kinase; Organophosphonates; Small Molecule Libraries; Smallpox; Species Specificity; Structure-Activity Relationship; Thermodynamics; Variola virus; Viral Proteins | 2015 |
The efficacy and pharmacokinetics of brincidofovir for the treatment of lethal rabbitpox virus infection: a model of smallpox disease.
Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Injections, Intradermal; Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia; Vaccinia virus; Variola virus | 2015 |
Buccal viral DNA as a trigger for brincidofovir therapy in the mousepox model of smallpox.
Topics: Animals; Antiviral Agents; Cytosine; Disease Models, Animal; DNA, Viral; Ectromelia virus; Ectromelia, Infectious; Mice; Mouth Mucosa; Organophosphonates; Orthopoxvirus; Smallpox | 2017 |
Biodefence since 9/11: The price of protection.
Topics: Animals; Antiviral Agents; Biomedical Research; Bioterrorism; Budgets; Cytosine; Disease Models, Animal; Humans; Male; Organophosphonates; Security Measures; September 11 Terrorist Attacks; Smallpox; Tularemia; United States; Vaccines; Young Adult | 2011 |
Scientific report: highlights of 24th ICAR, 8-11 May 2011, Sofia, Bulgaria.
Topics: Adenine; Animals; Antiviral Agents; Arenavirus; Chemistry, Pharmaceutical; Communicable Diseases, Emerging; Cytosine; Flavivirus; Hepacivirus; HIV Seropositivity; Humans; Organophosphonates; Prodrugs; Smallpox; Tenofovir; Virus Replication | 2011 |
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox.
Topics: Animals; Benzamides; Biomarkers, Pharmacological; Cell Line; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Ectromelia virus; Ectromelia, Infectious; Female; Humans; Isoindoles; Mice; Mice, Hairless; Mice, Inbred C57BL; Monkeypox virus; Organophosphonates; Smallpox; Variola virus; Virus Replication | 2012 |
In vitro characterization of a nineteenth-century therapy for smallpox.
Topics: Animals; Canada; Cell Line; Cidofovir; Cytosine; Fluorescent Antibody Technique; HeLa Cells; History, 19th Century; Humans; In Vitro Techniques; Organophosphonates; Phytotherapy; Plant Extracts; Rabbits; Real-Time Polymerase Chain Reaction; Sarraceniaceae; Smallpox; United States; Variola virus; Virus Replication | 2012 |
Gearing up for smallpox.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Humans; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States; Variola virus | 2002 |
The smallpox vaccine and postvaccinal encephalitis.
Topics: Animals; Antibodies, Viral; Antiviral Agents; Bioterrorism; Cidofovir; Contraindications; Cytosine; Encephalomyelitis, Acute Disseminated; Female; gamma-Globulins; History, 19th Century; History, 20th Century; Humans; Male; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; Vaccination | 2002 |
Smallpox--eradicated, but a growing terror threat.
Topics: Antiviral Agents; Biological Warfare; Bioterrorism; Cidofovir; Cytosine; Europe; History, 16th Century; History, 18th Century; History, 20th Century; History, Ancient; History, Medieval; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; USSR | 2002 |
Boom, or bust?
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Animals; Bacterial Vaccines; Biomedical Research; Bioterrorism; Cidofovir; Cytosine; Federal Government; Humans; Influenza Vaccines; Organophosphonates; Organophosphorus Compounds; Research Personnel; Research Support as Topic; Smallpox; United States | 2003 |
Unanimous vote approves tweak to smallpox genome.
Topics: Cidofovir; Cytosine; Drug Evaluation, Preclinical; Genes, Reporter; Genetic Engineering; Genome, Viral; Humans; Organophosphonates; Smallpox; Smallpox Vaccine; Variola virus; World Health Organization | 2004 |
In vivo imaging of cidofovir treatment of cowpox virus infection.
Topics: Animals; Antiviral Agents; Bioterrorism; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; DNA Replication; Drug Evaluation, Preclinical; Female; Green Fluorescent Proteins; Humans; Image Processing, Computer-Assisted; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Organophosphonates; Recombination, Genetic; Smallpox; Treatment Outcome; Vero Cells; Virus Replication | 2007 |
Rabbitpox virus and vaccinia virus infection of rabbits as a model for human smallpox.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Organophosphonates; Poxviridae Infections; Rabbits; Smallpox; Survival Rate; Vaccinia; Vaccinia virus; Viremia | 2007 |
Cidofovir protects mice against lethal aerosol or intranasal cowpox virus challenge.
Topics: Administration, Intranasal; Aerosols; Animals; Antiviral Agents; Bronchi; Cidofovir; Cowpox; Cytosine; Female; Hemorrhage; Mice; Mice, Inbred BALB C; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pulmonary Alveoli; Smallpox; Vaccination | 2000 |
Bioterrorism. Blocking smallpox: a second defense.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Disease Models, Animal; Disease Outbreaks; Humans; Macaca fascicularis; Military Medicine; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States; Variola virus; World Health Organization | 2001 |
Smallpox eradication: destruction of variola virus stocks.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Humans; Macaca fascicularis; Mice; Models, Animal; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Public Health; Sequence Analysis, DNA; Smallpox; Smallpox Vaccine; Variola virus; World Health Organization | 2002 |
Orally available cidofovir derivative active against smallpox.
Topics: Administration, Oral; Cidofovir; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox | 2002 |
Oral drug and old vaccine renew smallpox bioterror debate.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Contraindications; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States | 2002 |