Compounds > organophosphonates
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organophosphonates and Leukemia, Myeloid, Acute

organophosphonates has been researched along with Leukemia, Myeloid, Acute in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's3 (16.67)18.2507
2000's4 (22.22)29.6817
2010's9 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bai, L; Chen, J; Chinnaswamy, K; Dai, L; Kumar, P; Liu, L; Liu, Z; McEachern, D; Meagher, JL; Stuckey, JA; Sun, D; Wang, M; Wang, S; Wen, B; Xu, R; Yang, CY; Yi, H; Zhao, Y; Zhou, H1
Azar, MM; Hibbert, KA; Lane, RJ; Shepard, JO1
Beadle, JR; He, R; Hostetler, KY; Khoury, H; Minden, MD; Schimmer, A1
Allen, SL; Damon, L; Egyed, M; Erba, HP; Horst, HA; Jang, JH; Lundberg, AS; Masszi, T; Mazzola, E; Neuberg, D; Pigneux, A; Powell, B; Rizzieri, D; Sekeres, MA; Selleslag, D; Solomon, SR; Stone, RM; Stuart, RK; Tallman, MS; Venugopal, P; Warzocha, K; Wetzler, M1
Benedetti, E; Ceccherini-Nelli, L; Focosi, D; Galimberti, S; Maggi, F; Papineschi, F; Petrini, M; Pistolesi, D1
Cinek, O; Formankova, R; Hubacek, P; Keslova, P; Lochmanova, J; Pochop, P; Sedlacek, P; Stary, J; Zajac, M1
Tallman, M1
Allen, SL; Bennett, JM; Budman, DR; Capizzi, RL; Kolitz, JE; Lundberg, AS1
Chen, CH; Chiang, LT; Ko, BS; Yao, M1
Allen, SL; Lundberg, AS1
Feldman, EJ1
Freeman, CL; Giles, FJ; Swords, R1
Fouillard, L; Gozlan, J; Serfaty, L1
Benvenuto, JA; Johnston, DA; Nishioka, K1
Levine, JF; LoPresti, AE; Mendel, DB; Munk, GB; Tai, CY1
Benvenuto, JA; Beran, M; Estey, E; Felder, TB; Keating, M; O'Brien, S1
Davies, LC; Harrap, KR; Orr, RM; Powles, RL; Stock, JA; Taylor, GA1
Andersson, BS; Bakic, M; Beran, M; Newman, RA; Silberman, LE; Zwelling, LA1

Reviews

2 review(s) available for organophosphonates and Leukemia, Myeloid, Acute

ArticleYear
Amonafide: a potential role in treating acute myeloid leukemia.
    Expert opinion on investigational drugs, 2011, Volume: 20, Issue:7

    Topics: Adenine; Animals; Antineoplastic Agents; Clinical Trials as Topic; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Survival Rate; Treatment Outcome

2011
Amonafide: a future in treatment of resistant and secondary acute myeloid leukemia?
    Expert review of hematology, 2012, Volume: 5, Issue:1

    Topics: Adenine; Antineoplastic Agents; Clinical Trials as Topic; Female; Humans; Leukemia, Myeloid, Acute; Male; Naphthalimides; Organophosphonates; Topoisomerase II Inhibitors

2012

Trials

3 trial(s) available for organophosphonates and Leukemia, Myeloid, Acute

ArticleYear
Phase III open-label randomized study of cytarabine in combination with amonafide L-malate or daunorubicin as induction therapy for patients with secondary acute myeloid leukemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Apr-10, Volume: 33, Issue:11

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Prospective Studies; Remission Induction; Time Factors; Treatment Outcome; Young Adult

2015
Phase I trials of amonafide as monotherapy and in combination with cytarabine in patients with poor-risk acute myeloid leukemia.
    Leukemia research, 2010, Volume: 34, Issue:4

    Topics: Adenine; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Remission Induction; Risk Factors; Treatment Outcome; Young Adult

2010
Phase I clinical investigation of benzisoquinolinedione (amonafide) in adults with refractory or relapsed acute leukemia.
    Cancer research, 1991, Feb-01, Volume: 51, Issue:3

    Topics: Acute Disease; Adenine; Adult; Aged; Antineoplastic Agents; Drug Administration Schedule; Drug Evaluation; Female; Humans; Imides; Isoquinolines; Leukemia; Leukemia, Myeloid, Acute; Male; Middle Aged; Naphthalimides; Organophosphonates; Precursor Cell Lymphoblastic Leukemia-Lymphoma

1991

Other Studies

13 other study(ies) available for organophosphonates and Leukemia, Myeloid, Acute

ArticleYear
Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein.
    Journal of medicinal chemistry, 2019, 12-26, Volume: 62, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; Azocines; Cell Proliferation; Drug Design; Drug Discovery; Female; Humans; Indoles; Leukemia, Myeloid, Acute; Mice; Mice, SCID; Molecular Structure; Organophosphonates; Protein Conformation; Proteolysis; STAT3 Transcription Factor; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
Case 1-2018. A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure.
    The New England journal of medicine, 2018, 01-11, Volume: 378, Issue:2

    Topics: Adenoviridae; Adenoviridae Infections; Adult; Antiviral Agents; Cidofovir; Cytosine; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Lung; Nasopharynx; Opportunistic Infections; Organophosphonates; Radiography, Thoracic; Renal Insufficiency; Respiratory Insufficiency; Stem Cell Transplantation; Tomography, X-Ray Computed; Viral Load

2018
Octadecyloxyethyl Adefovir Exhibits Potent in vitro and in vivo Cytotoxic Activity and Has Synergistic Effects with Ara-C in Acute Myeloid Leukemia.
    Chemotherapy, 2018, Volume: 63, Issue:4

    Topics: Adenine; Animals; Apoptosis; Caspases; Cell Cycle Checkpoints; Cytarabine; DNA Damage; Drug Compounding; Drug Resistance, Neoplasm; Drug Synergism; Female; Histones; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Organophosphonates; Poly(ADP-ribose) Polymerases; Transplantation, Heterologous; Tumor Cells, Cultured

2018
Hyperbaric oxygen therapy in BKV-associated hemorrhagic cystitis refractory to intravenous and intravesical cidofovir: case report and review of literature.
    Leukemia research, 2009, Volume: 33, Issue:4

    Topics: Administration, Intravesical; Adult; Antineoplastic Agents; Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytomegalovirus Infections; Cytosine; Hematopoietic Stem Cell Transplantation; Hematuria; Humans; Hyperbaric Oxygenation; Leukemia, Myeloid, Acute; Male; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections

2009
Cytomegalovirus encephalitis/retinitis in allogeneic haematopoietic stem cell transplant recipient treated successfully with combination of cidofovir and foscarnet.
    Pediatric transplantation, 2009, Volume: 13, Issue:7

    Topics: Adolescent; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Encephalitis, Viral; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Organophosphonates; Retinitis; Treatment Outcome

2009
Existing and emerging therapeutic options for the treatment of acute myeloid leukemia.
    Clinical advances in hematology & oncology : H&O, 2008, Volume: 6, Issue:11

    Topics: Adenine; Adenine Nucleotides; Aminoglycosides; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Arabinonucleosides; Carbazoles; Clofarabine; Cytarabine; Dasatinib; Daunorubicin; fms-Like Tyrosine Kinase 3; Furans; Gemtuzumab; Humans; Leukemia, Myeloid, Acute; Naphthalimides; Organophosphonates; Prognosis; Protein Kinase Inhibitors; Pyrimidines; Sesquiterpenes; Staurosporine; Stem Cell Transplantation; Thiazoles; Tretinoin

2008
Development of immunity against hepatitis B virus after donor lymphocyte infusion in a peripheral blood stem cell transplantation recipient with chronic hepatitis B.
    Infection, 2011, Volume: 39, Issue:4

    Topics: Adenine; Adoptive Transfer; Antiviral Agents; DNA, Viral; Drug Combinations; Female; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Humans; Lamivudine; Leukemia, Myeloid, Acute; Lymphocyte Transfusion; Middle Aged; Organophosphonates; Peripheral Blood Stem Cell Transplantation; Taiwan; Treatment Outcome; Unrelated Donors

2011
Does therapy-related AML have a poor prognosis, independent of the cytogenetic/molecular determinants?
    Best practice & research. Clinical haematology, 2011, Volume: 24, Issue:4

    Topics: Adenine; Anthracyclines; Antineoplastic Agents; Biomarkers, Tumor; Cytarabine; Cytogenetics; Female; Germany; Humans; Leukemia, Myeloid, Acute; Middle Aged; Myelodysplastic Syndromes; Naphthalimides; Naphthyridines; Organophosphonates; Prognosis; Remission Induction; Retrospective Studies; Survival Rate; Thiazoles

2011
Adefovir therapy for lamivudine escape and hepatitis B virus reactivation after reduced intensity conditioning allogeneic stem cell transplantation.
    Bone marrow transplantation, 2006, Volume: 37, Issue:6

    Topics: Adenine; Adult; Antineoplastic Agents; Combined Modality Therapy; Female; Hepatitis B; Hepatitis B virus; Humans; Lamivudine; Leukemia, Myeloid, Acute; Organophosphonates; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Viral Load; Virus Activation

2006
The correlation of response with plasma pharmacokinetics and polyamine concentrations in patients with acute myelogenous leukemia receiving amonafide.
    Cancer letters, 1993, Jul-16, Volume: 70, Issue:3

    Topics: Adenine; Antineoplastic Agents; Chromatography, High Pressure Liquid; Half-Life; Humans; Imides; Isoquinolines; Leukemia, Myeloid, Acute; Leukocyte Count; Metabolic Clearance Rate; Naphthalimides; Organophosphonates; Polyamines; Regression Analysis; Time Factors

1993
Successful treatment of an acyclovir- and foscarnet-resistant herpes simplex virus type 1 lesion with intravenous cidofovir.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:2

    Topics: Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Organophosphonates; Organophosphorus Compounds

1998
Inhibition of human leukaemic thymidylate kinase and L1210 ribonucleotide reductase by dinucleotides of adenosine and thymidine and their phosphonate analogues.
    Biochemical pharmacology, 1988, Feb-15, Volume: 37, Issue:4

    Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Humans; Kinetics; Leukemia L1210; Leukemia, Myeloid, Acute; Nucleoside-Phosphate Kinase; Oligonucleotides; Organophosphonates; Phosphotransferases; Ribonucleoside Diphosphate Reductase; Ribonucleotide Reductases; Thymidine

1988
In vitro toxicity and DNA cleaving capacity of benzisoquinolinedione (nafidimide; NSC 308847) in human leukemia.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: Adenine; Amsacrine; Cell Line; Clone Cells; DNA; DNA Topoisomerases, Type I; Doxorubicin; Electrophoresis, Agar Gel; Humans; Imides; In Vitro Techniques; Intercalating Agents; Isoquinolines; Leukemia, Myeloid, Acute; Mathematics; Naphthalimides; Organophosphonates

1987