Page last updated: 2024-09-05

organophosphonates and Herpes Simplex Virus Infection

organophosphonates has been researched along with Herpes Simplex Virus Infection in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (12.33)	18.7374
1990's	19 (26.03)	18.2507
2000's	21 (28.77)	29.6817
2010's	23 (31.51)	24.3611
2020's	1 (1.37)	2.80

Authors

Authors	Studies
Kotton, BD; Kotton, CN	1
Andrei, G; Gillemot, S; Snoeck, R; Topalis, D	1
Cheteyan, L; Huang, YT; Jakubowski, AA; Kim, SJ; Lee, YJ; Neofytos, D; Papadopoulos, EB; Papanicolaou, GA	1
Arnold, E; Balzarini, J; Das, K; Dehaen, W; Ford, A; John, J; Maguire, A; Maguire, NM	1
Feng, J; Hang, TJ; Jia, YY; Lu, CT; Song, Y; Sun, Y; Wang, S; Wen, AD; Yang, ZF; Zhao, JY	1
Andrei, G; Balestra, E; Balzarini, J; Holý, A; Huskens, D; Introini, A; Liekens, S; Margolis, L; Perno, CF; Schols, D; Snoeck, R; Vanpouille, C; Zicari, S	1
Agut, H; Boutolleau, D; Burrel, S; Caumes, E; Epelboin, L; Katlama, C; Regnier, S; Seang, S; Valantin, MA; Voujon, D	1
Casapia, M; Glidden, DV; Grant, RM; Hoagland, B; Lama, JR; Liu, AY; Marcus, JL; Mayer, KH; McMahan, V; Montoya-Herrera, O	1
Alaibac, M; Peserico, A; Piaserico, S; Sandini, E	1
Chemaly, RF; Hosing, C; Lahoti, A; Saunders, IM; Trevino, C; Westmoreland, M	1
Beadle, JR; Cheng, L; Freeman, WR; Hostetler, KY; Hou, H; Lee, S; Ma, F; Nan, K	1
Breuer, J; De, SK; Hart, JC	1
Epstein, JB; Gharapetian, S; Lill, M; Rejali, AR; Tzachanis, D; Zabner, R	1
Edelmann, A; Hofmann, J; Kühl, JS; Sauerbrei, A; Voigt, S	1
Ariza-Heredia, EJ; Chemaly, RF; El Chaer, F; El-Haddad, D; Gulbis, AM; Mulanovich, VE; Shah, DP; Shpall, EJ; Vanichanan, J	1
Barshak, MB; Durand, ML; Foster, CS; Kim, IK; Mali, JO; Scott, NL; Stryjewski, TP; Tobin, EH; Young, LH	1
Cieśluk, B; Dzieciatkowski, T; Majewska, A; Łuczak, M	1
Bernardin, R; Castelo-Soccio, L; Goldstein, SA; Kovarik, C; Stern, J	1
Collins, DJ; Kern, ER; Lampert, B; Painter, GR; Quenelle, DC; Rice, TL	1
Kaul, R; Raboud, JM; Tan, DH; Walmsley, SL	1
Andrei, G; Balzarini, J; Hocková, D; Holý, A; Snoeck, R	1
Ellis, RM; Hood, AF; Mohr, MR; Oldfield, EC	1
Hartline, CB; Kern, ER; Lanier, ER; Prichard, MN; Quenelle, DC	1
Bohn, K; Hamprecht, K; Heim, A; Hoffmann, D; Hofmann, J; Jahn, G; Sauerbrei, A; Schnitzler, P; Weissbrich, B; Wutzler, P; Zell, R	1
Armistead, P; Dean, A; Khan, T; Muluneh, B	1
Snoeck, R	1
Morfin, F; Thouvenot, D	1
Afouna, MI; Fincher, TK; Reddy, IK; Zaghloul, AA	1
Blauvelt, A; Sanchez, S; Toro, JR; Turiansky, G	1
Chilukuri, S; Rosen, T	1
Aleksandrova, LA; Andronova, VL; Karpenko, IL; Skoblov, IuS	1
Hirschel, B; Pechère, M; Piguet, V; Saurat, JH; Schiffer, V; Toutous-Trellu, L	1
Aoki, K; Eto, T; Gondo, H; Harada, M; Henzan, H; Kato, K; Miyamoto, T; Nagafuji, K; Nagatoshi, Y; Obama, K; Ohba, T	1
Aldern, K; Beadle, JR; Bessho, K; Bovet, JM; Cheng, L; Freeman, WR; Hostetler, KY; Koh, HJ; Lee, J; Toyoguchi, M	1
Bessesen, M; Krause, PR; Madinger, N; Patel, A; Weinberg, A; Wyles, DL	1
Aldern, KA; Beadle, JR; Hartline, CB; Hostetler, KY; Keith, KA; Kern, ER; Ruiz, JC	1
Andrei, G; De Clercq, E; Fiten, P; Gordts, B; Goubau, P; Opdenakker, G; Selleslag, D; Snoeck, R; van Landuyt, H	1
Andrei, G; De Clercq, E; Fiten, P; Froeyen, M; Opdenakker, G; Snoeck, R	1
Assil, KK; Bergeron-Lynn, G; Besen, G; De Clercq, E; Flores-Aguilar, M; Gangan, P; Kupperman, BD; Munguia, D; Pursley, M; Vuong, C	1
Andrei, G; Balzarini, J; Clumeck, N; De Clercq, E; Gérard, M; Hedderman, A; Sadzot-Delvaux, C; Silverman, A; Snoeck, R; Tricot, G	1
Davidson, JM; Drew, WL; Fisher, PE; Glutzer, E; Jaffe, HS; Lalezari, JP; Miner, D; Owen, WF; Safrin, S	1
Bergeron-Lynn, G; Chandler, B; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Huang, JS; Munguia, D; Vuong, C; Wiley, CA	1
Andrei, G; Clumeck, N; De Clercq, E; Gerard, M; Sadzot-Delvaux, C; Snoeck, R; Tricot, G	1
Assil, KK; Bergeron-Lynn, G; Besen, G; Connor, JD; De Clercq, E; Freeman, WR; Kuppermann, BD; Munguia, D; Pursley, M; Vuong, C; Wiley, CA	1
Boggs, J; Cheung, T; Corey, L; Drew, WL; Feinberg, J; Gathe, J; Jaffe, HS; Kessler, H; Kramer, F; Lalezari, J; Lee, S; McGuire, B; Safrin, S; Schacker, T	1
Luks-Golger, DB; Martinez, CM	1
Levine, JF; LoPresti, AE; Mendel, DB; Munk, GB; Tai, CY	1
Engler, RJ; Katial, RK; Myers, KW	1
Don, PC; Kaufmann, M; Lateef, F; Weinberg, JM; White, SM	1
Afouna, MI; DeClercq, E; El-Shattawy, HH; Ghanem, AH; Higuchi, WI; Kern, ER; Mehta, SC	1
Aymard, M; Chen, Y; Devergie, A; Espérou, H; Garderet, L; Garrait, V; Gluckman, E; Hocqueloux, L; Leleu, G; Molina, JM; Morfin, F; Morinet, F; Ribaud, P; Rocha, V; Scieux, C; Sélimi, F; Socié, G; Thouvenot, D	1
Blot, N; Dehesdin, D; Janvresse, C; Schneider, P; Tron, P; Vannier, JP; Young, P	1
Bordigoni, P; Carret, AS; Corsaro, D; Dauendorffer, JN; Edert, D; Le Faou, A; Venard, V	1
Bryant, P; Carapetis, J; Curtis, N; Sasadeusz, J; Waters, K	1
Ait Arkoub, Z; Arnulf, B; Chebbi, F; Fillet, AM; Lefrere, F; Varet, B	1
Bestman-Smith, J; Boivin, G	1
Geusau, A; Kopp, T; Rieger, A; Stingl, G	1
Horvath, P	1
Friedman-Kien, AE; Klein, RJ	1
Boyd, MR; Harris, SR	1
Renis, HE	1
Baron, S; Conliffe, MA; Lefkowitz, E; Worthington, M	1
Hitchcock, MJ; Martin, JC	1
De Castro, LM; De Clercq, E; Gangemi, JD; Ghaffar, A; Kern, ER; Mayer, EP; Vogt, PE	1
Datema, R; Yang, H	1
De Clercq, E; Holý, A	1
Balzarini, J; Cozens, RM; De Clercq, E; Gangemi, JD; Hochkeppel, HK	1
De Clercq, E; Holý, A; Rosenberg, I	1
Bernaerts, R; De Clercq, E; Holý, A; Merta, A; Rosenberg, I; Sakuma, T; Votruba, I	1
de Clercq, E	1

Reviews

10 review(s) available for organophosphonates and Herpes Simplex Virus Infection

Article	Year
Resistant herpes simplex virus infections - who, when, and what's new? Current opinion in infectious diseases, 2022, 12-01, Volume: 35, Issue:6 Topics: Acyclovir; Antiviral Agents; Cytosine; Foscarnet; Herpes Simplex; Herpesviridae Infections; Humans; Organophosphonates	2022
Alpha-carboxynucleoside phosphonates: direct-acting inhibitors of viral DNA polymerases. Future medicinal chemistry, 2019, Volume: 11, Issue:2 Topics: Animals; Antiviral Agents; DNA-Directed DNA Polymerase; Drug Discovery; Exodeoxyribonucleases; Herpes Simplex; Humans; Models, Molecular; Nucleic Acid Synthesis Inhibitors; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Viral Proteins; Virus Diseases; Viruses	2019
Cutaneous viral infections in organ transplant patients. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014, Volume: 149, Issue:4 Topics: Acitretin; Administration, Cutaneous; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Dermatologic Agents; Hair Diseases; Herpes Simplex; Herpes Zoster; Humans; Ichthyosis; Imiquimod; Immunocompromised Host; Immunosuppressive Agents; Incidence; Italy; Molluscum Contagiosum; Organ Transplantation; Organophosphonates; Skin Diseases, Viral; Transplant Recipients; Warts	2014
Herpes simplex virus and varicella zoster virus: recent advances in therapy. Current opinion in infectious diseases, 2015, Volume: 28, Issue:6 Topics: Antiviral Agents; Clinical Trials as Topic; Cytosine; Drug Discovery; Drug Evaluation; Drug Resistance, Viral; Herpes Simplex; Herpes Zoster; Humans; Microbial Sensitivity Tests; Organophosphonates; Treatment Outcome; Virus Replication	2015
[Perspectives for the treatment and prevention of herpes simplex infections]. Annales de dermatologie et de venereologie, 2002, Volume: 129, Issue:4 Pt 2 Topics: 2-Aminopurine; Acyclovir; Aminoquinolines; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Famciclovir; Herpes Simplex; Herpes Simplex Virus Vaccines; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Imiquimod; Interferon Inducers; Organophosphonates; Organophosphorus Compounds; Valacyclovir; Valine	2002
Herpes simplex virus resistance to antiviral drugs. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2003, Volume: 26, Issue:1 Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Drug Resistance, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Herpes Simplex; Humans; Immunocompromised Host; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Proteins; Virus Replication	2003
Topical cidofovir for the treatment of dermatologic conditions: verruca, condyloma, intraepithelial neoplasia, herpes simplex and its potential use in smallpox. Dermatologic clinics, 2003, Volume: 21, Issue:2 Topics: Administration, Cutaneous; Administration, Topical; Antiviral Agents; Carcinoma in Situ; Carcinoma, Squamous Cell; Cidofovir; Condylomata Acuminata; Cytosine; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Infectious; Skin Neoplasms; Smallpox; Warts	2003
Management of acyclovir-resistant herpes simplex virus. Dermatologic clinics, 2003, Volume: 21, Issue:2 Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Foscarnet; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Stomatitis, Herpetic; Trifluridine; Vidarabine	2003
Cidofovir use in acyclovir-resistant herpes infection. The Annals of pharmacotherapy, 1997, Volume: 31, Issue:12 Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Simplexvirus	1997
Virus-drug resistance: thymidine kinase-deficient (TK-) mutants of herpes simplex virus. Therapeutic approaches. Annali dell'Istituto superiore di sanita, 1987, Volume: 23, Issue:4 Topics: Acyclovir; Adenine; Antiviral Agents; Drug Resistance, Microbial; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Thymidine Kinase; Viral Proteins	1987

Trials

6 trial(s) available for organophosphonates and Herpes Simplex Virus Infection

Article	Year
Impact on L-carnitine Homeostasis of Short-term Treatment with the Pivalate Prodrug Tenofovir Dipivoxil. Basic & clinical pharmacology & toxicology, 2013, Volume: 113, Issue:6 Topics: Adenine; Adult; Antiviral Agents; Carnitine; Dose-Response Relationship, Drug; Female; Hepatitis B; Herpes Simplex; Homeostasis; Humans; Male; Organophosphonates; Prodrugs; Tenofovir	2013
[Treatment of cutaneous human papilloma virus, poxvirus and herpes simplex virus infections with topical cidofovir in HIV positive patients]. Annales de dermatologie et de venereologie, 2004, Volume: 131, Issue:5 Topics: Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Poxviridae Infections; Skin Diseases, Viral	2004
Cidofovir for treating adenoviral hemorrhagic cystitis in hematopoietic stem cell transplant recipients. Bone marrow transplantation, 2004, Volume: 34, Issue:10 Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cystitis; Cytomegalovirus Infections; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Male; Middle Aged; Opportunistic Infections; Organophosphonates; Treatment Outcome	2004
A randomized, double-blind, placebo-controlled trial of cidofovir gel for the treatment of acyclovir-unresponsive mucocutaneous herpes simplex virus infection in patients with AIDS. The Journal of infectious diseases, 1997, Volume: 176, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Double-Blind Method; Drug Resistance, Microbial; Female; Foscarnet; Gels; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Mouth Mucosa; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells	1997
NDA filed to treat refractory herpes. AIDS patient care and STDs, 1997, Volume: 11, Issue:2 Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds; Randomized Controlled Trials as Topic; Recurrence; United States; United States Food and Drug Administration	1997
[Recurrent herpes simplex. The situation in the United States]. Zeitschrift fur Hautkrankheiten, 1977, May-01, Volume: 52, Issue:9 Topics: Clinical Trials as Topic; Deoxyglucose; Herpes Simplex; Humans; Idoxuridine; Inosine Pranobex; Interferons; Levamisole; Organophosphonates; Ribavirin; Transfer Factor; Trifluridine; United States; Vidarabine	1977

Other Studies

57 other study(ies) available for organophosphonates and Herpes Simplex Virus Infection

Article	Year
The Anti-Human Immunodeficiency Virus Drug Tenofovir, a Reverse Transcriptase Inhibitor, Also Targets the Herpes Simplex Virus DNA Polymerase. The Journal of infectious diseases, 2018, 02-14, Volume: 217, Issue:5 Topics: Acyclovir; Amino Acid Substitution; Antiviral Agents; Cells, Cultured; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mutation, Missense; Organophosphonates; Pyrimidines; Reverse Transcriptase Inhibitors; Selection, Genetic; Sequence Analysis, DNA; Tenofovir; Viral Proteins	2018
Efficacy of brincidofovir as prophylaxis against HSV and VZV in hematopoietic cell transplant recipients. Transplant infectious disease : an official journal of the Transplantation Society, 2018, Volume: 20, Issue:6 Topics: Adult; Aged; Antibiotic Prophylaxis; Child; Child, Preschool; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 3, Human; Humans; Infant; Male; Middle Aged; Organophosphonates; Retrospective Studies; Simplexvirus; Treatment Outcome; Varicella Zoster Virus Infection; Young Adult	2018
A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity. PLoS pathogens, 2013, Volume: 9, Issue:7 Topics: Animals; Anti-HIV Agents; Antiviral Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV; Humans; Immunologic Factors; Leukocytes, Mononuclear; Lymphoid Tissue; Mice; Mice, Hairless; Mice, Nude; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Prodrugs; Pyrimidines; Reverse Transcriptase Inhibitors; Tissue Culture Techniques	2013
Long-term follow-up of HIV-infected patients once diagnosed with acyclovir-resistant herpes simplex virus infection. International journal of STD & AIDS, 2014, Volume: 25, Issue:9 Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Follow-Up Studies; Foscarnet; Herpes Simplex; HIV Infections; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Retrospective Studies; Skin Diseases, Viral; Skin Ulcer; Socioeconomic Factors; Thymidine Kinase; Treatment Outcome	2014
Daily oral emtricitabine/tenofovir preexposure prophylaxis and herpes simplex virus type 2 among men who have sex with men. PloS one, 2014, Volume: 9, Issue:3 Topics: Adenine; Adolescent; Adult; Aged; Antiviral Agents; Chemoprevention; Deoxycytidine; Emtricitabine; Herpes Simplex; Herpesvirus 2, Human; Homosexuality, Male; Humans; Incidence; Male; Middle Aged; Organophosphonates; Prevalence; Risk Factors; Tenofovir; Young Adult	2014
Topical cidofovir-induced acute kidney injury in two severely immunocompromised patients with refractory multidrug-resistant herpes simplex virus infections. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2016, Volume: 22, Issue:2 Topics: Acute Kidney Injury; Administration, Topical; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Herpes Simplex; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates	2016
Micelle formulation of hexadecyloxypropyl-cidofovir (HDP-CDV) as an intravitreal long-lasting delivery system. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2015, Volume: 89 Topics: Animals; Antiviral Agents; Chemistry, Pharmaceutical; Cytosine; Delayed-Action Preparations; Drug Delivery Systems; Guinea Pigs; Half-Life; Herpes Simplex; Herpesvirus 1, Human; Intravitreal Injections; Micelles; Organophosphonates; Prodrugs; Rabbits; Retina; Vitreous Body	2015
Complex management of resistant oral herpes simplex virus infection following hematopoietic stem cell transplantation: potential role of topical cidofovir. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016, Volume: 24, Issue:8 Topics: Administration, Topical; Aged; Antiviral Agents; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Male; Organophosphonates; Transplantation Conditioning	2016
Brincidofovir clearance of acyclovir-resistant herpes simplex virus-1 and adenovirus infection after stem cell transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:5 Topics: Acyclovir; Adenoviridae; Adenovirus Infections, Human; Antibiotic Prophylaxis; Antiviral Agents; Child, Preschool; Cidofovir; Cytosine; DNA, Viral; Drug Resistance, Viral; Epstein-Barr Virus Infections; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpes Zoster; Herpesvirus 1, Human; Herpesvirus 3, Human; Herpesvirus 4, Human; Humans; Immunocompromised Host; Meningoencephalitis; Mucositis; Myelodysplastic Syndromes; Organophosphonates; Rituximab; Viral Load	2016
Brincidofovir (CMX-001) for refractory and resistant CMV and HSV infections in immunocompromised cancer patients: A single-center experience. Antiviral research, 2016, Volume: 134 Topics: Aged; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesviridae Infections; Humans; Immunocompromised Host; Male; Middle Aged; Neoplasms; Organophosphonates	2016
Treatment of Refractory Acute Retinal Necrosis with Intravenous Foscarnet or Cidofovir. Ocular immunology and inflammation, 2018, Volume: 26, Issue:2 Topics: Aged; Aged, 80 and over; Antiviral Agents; Cidofovir; Cytosine; Eye Infections, Viral; Foscarnet; Herpes Simplex; Herpes Zoster Ophthalmicus; Herpesvirus 3, Human; Humans; Infusions, Intravenous; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retinal Necrosis Syndrome, Acute; Retrospective Studies; Simplexvirus; Vitreous Body	2018
[In vitro acyclovir and cidofovir susceptibilities of human herpesvirus type 1 clinical isolates]. Medycyna doswiadczalna i mikrobiologia, 2008, Volume: 60, Issue:2 Topics: Acyclovir; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Herpes Simplex; Herpesvirus 1, Human; Humans; Microbial Sensitivity Tests; Organophosphonates; Vero Cells	2008
Successful treatment of acyclovir-resistant herpes simplex virus with intralesional cidofovir. Archives of dermatology, 2010, Volume: 146, Issue:2 Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Facial Dermatoses; Herpes Simplex; Humans; Injections, Intralesional; Male; Organophosphonates	2010
Efficacy of CMX001 against herpes simplex virus infections in mice and correlations with drug distribution studies. The Journal of infectious diseases, 2010, Nov-15, Volume: 202, Issue:10 Topics: Administration, Oral; Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Mice; Mice, Inbred BALB C; Organophosphonates; Tissue Distribution	2010
No impact of oral tenofovir disoproxil fumarate on herpes simplex virus shedding in HIV-infected adults. AIDS (London, England), 2011, Jan-14, Volume: 25, Issue:2 Topics: Adenine; Adult; AIDS-Related Opportunistic Infections; Canada; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Tenofovir; Virus Shedding	2011
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity. Bioorganic & medicinal chemistry, 2011, Aug-01, Volume: 19, Issue:15 Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Herpes Simplex; HIV; HIV Infections; Humans; Mice; Nucleosides; Organophosphonates; Simplexvirus; Structure-Activity Relationship; Vaccinia; Vaccinia virus; Virus Diseases; Viruses	2011
Recalcitrant herpetic scrotal ulcer as a manifestation of immune reconstitution inflammatory syndrome. Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:2 Topics: Administration, Topical; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; Biopsy, Needle; Cidofovir; Cytosine; Diagnosis, Differential; Follow-Up Studies; Herpes Simplex; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Immunohistochemistry; Male; Organophosphonates; Scrotum; Severity of Illness Index; Skin Ulcer; Treatment Outcome; Wound Healing	2011
CMX001 potentiates the efficacy of acyclovir in herpes simplex virus infections. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10 Topics: Acyclovir; Animals; Antiviral Agents; Cells, Cultured; Cytosine; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Mice; Mice, Inbred BALB C; Organophosphonates	2011
Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2. Antiviral therapy, 2011, Volume: 16, Issue:8 Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Bromodeoxyuridine; Child; Child, Preschool; Cidofovir; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Foscarnet; Genotype; Guanine; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Infant; Male; Middle Aged; Mutation; Organophosphonates; Sequence Analysis, DNA; Thymidine Kinase; Viral Proteins	2011
Successful clearance of cutaneous acyclovir-resistant, foscarnet-refractory herpes virus lesions with topical cidofovir in an allogeneic hematopoietic stem cell transplant patient. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2013, Volume: 19, Issue:2 Topics: Acyclovir; Administration, Topical; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Gels; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Real-Time Polymerase Chain Reaction; Transplantation, Homologous; Treatment Outcome	2013
Effect of Azone upon the in vivo antiviral efficacy of cidofovir or acyclovir topical formulations in treatment/prevention of cutaneous HSV-1 infections and its correlation with skin target site free drug concentration in hairless mice. International journal of pharmaceutics, 2003, Mar-06, Volume: 253, Issue:1-2 Topics: Acyclovir; Adjuvants, Pharmaceutic; Administration, Topical; Animals; Antiviral Agents; Azepines; Cidofovir; Cytosine; Drug Administration Schedule; Female; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Permeability; Skin Absorption	2003
[Efficacy of 4'-thio-5-ethyl-2'-deoxyuridine (TEDU) and its derivatives in experimental infection in mice caused by herpes simplex virus]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2003, Volume: 48, Issue:5 Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Herpes Simplex; Herpesvirus 1, Human; Mice; Organophosphonates; Structure-Activity Relationship; Thionucleosides; Toxicity Tests, Acute; Vero Cells	2003
Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir. Investigative ophthalmology & visual science, 2004, Volume: 45, Issue:11 Topics: Animals; Antiviral Agents; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Cytosine; Drug Delivery Systems; Eye Infections, Viral; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Liposomes; Microfluidics; Organophosphonates; Prodrugs; Rabbits; Retina; Retinitis; Vitreous Body	2004
Development of herpes simplex virus disease in patients who are receiving cidofovir. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Sep-01, Volume: 41, Issue:5 Topics: Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Humans; Male; Organophosphonates; Simplexvirus	2005
Synthesis and antiviral evaluation of alkoxyalkyl-phosphate conjugates of cidofovir and adefovir. Antiviral research, 2007, Volume: 75, Issue:1 Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cowpox; Cytomegalovirus Infections; Cytosine; Herpes Simplex; HIV-1; Humans; In Vitro Techniques; Molecular Structure; Organophosphonates; Sensitivity and Specificity; Vaccinia	2007
Dual infection with polyomavirus BK and acyclovir-resistant herpes simplex virus successfully treated with cidofovir in a bone marrow transplant recipient. Transplant infectious disease : an official journal of the Transplantation Society, 2007, Volume: 9, Issue:2 Topics: Acyclovir; Adolescent; Antiviral Agents; BK Virus; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Organophosphonates; Polyomavirus Infections; Tumor Virus Infections	2007
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions. Antiviral therapy, 2007, Volume: 12, Issue:5 Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Genotype; Herpes Simplex; Herpesvirus 1, Human; Humans; Mice; Models, Molecular; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Phenotype; Protein Binding; Protein Conformation; Vero Cells; Viral Proteins; Virulence	2007
Long-term therapy for herpes retinitis in an animal model with high-concentrated liposome-encapsulated HPMPC. Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:5 Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Electroretinography; Eye Infections, Viral; Fundus Oculi; Herpes Simplex; Liposomes; Longitudinal Studies; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis	1995
Successful treatment of progressive mucocutaneous infection due to acyclovir- and foscarnet-resistant herpes simplex virus with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC). Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:4 Topics: Acyclovir; Administration, Topical; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; DNA Restriction Enzymes; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral; Thymidine Kinase	1994
Treatment with intravenous (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine of acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with AIDS. The Journal of infectious diseases, 1994, Volume: 170, Issue:3 Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Herpes Simplex; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus	1994
Long-acting therapy of viral retinitis with (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine. The Journal of infectious diseases, 1994, Volume: 169, Issue:3 Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Drug Therapy, Combination; Ganciclovir; Herpes Simplex; Herpesvirus 1, Human; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis; Time Factors	1994
A new topical treatment for resistant herpes simplex infections. The New England journal of medicine, 1993, Sep-23, Volume: 329, Issue:13 Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance; Herpes Simplex; Humans; Immunocompromised Host; Organophosphonates; Organophosphorus Compounds; Simplexvirus	1993
Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for long-acting therapy of viral retinitis. The Journal of infectious diseases, 1996, Volume: 173, Issue:1 Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Drug Carriers; Eye Infections, Viral; Herpes Simplex; Herpesvirus 1, Human; Injections; Liposomes; Organophosphonates; Organophosphorus Compounds; Rabbits; Retina; Retinitis; Vitreous Body	1996
Successful treatment of an acyclovir- and foscarnet-resistant herpes simplex virus type 1 lesion with intravenous cidofovir. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:2 Topics: Acyclovir; Adult; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Injections, Intravenous; Leukemia, Myeloid, Acute; Male; Organophosphonates; Organophosphorus Compounds	1998
Probenecid hypersensitivity in AIDS: a case report. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1998, Volume: 80, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Cidofovir; Cytosine; Drug Hypersensitivity; Herpes Simplex; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Probenecid; Uricosuric Agents	1998
Treatment of acyclovir-resistant, foscarnet-unresponsive HSV infection with topical cidofovir in a child with AIDS. Archives of dermatology, 1998, Volume: 134, Issue:9 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Anti-HIV Agents; Child, Preschool; Cidofovir; Cytosine; Drug Resistance, Microbial; Facial Dermatoses; Foscarnet; Herpes Simplex; Humans; Male; Organophosphonates; Organophosphorus Compounds; Treatment Failure	1998
Influence of the treatment protocol upon the in vivo efficacy of cidofovir (HPMPC) and of acyclovir (ACV) formulations in topical treatment of cutaneous HSV-1 infection in hairless mice. Journal of pharmaceutical sciences, 1999, Volume: 88, Issue:5 Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Female; Herpes Simplex; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Skin Diseases, Viral	1999
Resistant herpes simplex virus type 1 infection: an emerging concern after allogeneic stem cell transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, Volume: 31, Issue:4 Topics: Acyclovir; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cytosine; Drug Resistance, Microbial; Female; Foscarnet; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesvirus 1, Human; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Transplantation, Homologous	2000
Treatment of an acyclovir and foscarnet-resistant herpes simplex virus infection with cidofovir in a child after an unrelated bone marrow transplant. Bone marrow transplantation, 2000, Volume: 26, Issue:8 Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytosine; Drug Resistance; Female; Foscarnet; Herpes Simplex; Humans; Infant; Organophosphonates; Organophosphorus Compounds	2000
Gilead announces phase I/II data insufficient for marketing clearance of FORVADE topical gel to treat refractory herpes in patients with AIDS. AIDS patient care and STDs, 1997, Volume: 11, Issue:4 Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytosine; Herpes Simplex; Humans; Investigational New Drug Application; Organophosphonates; Organophosphorus Compounds; United States; United States Food and Drug Administration	1997
Acyclovir-resistant herpes: expanded access available for cidofovir gel (Forvade). AIDS treatment news, 1997, Feb-07, Issue:No 264 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cidofovir; Cytosine; Drug Approval; Gels; Herpes Simplex; Humans; Organophosphonates; Organophosphorus Compounds	1997
Infection due to acyclovir resistant herpes simplex virus in patients undergoing allogeneic hematopoietic stem cell transplantation. Pathologie-biologie, 2001, Volume: 49, Issue:7 Topics: Acute Disease; Acyclovir; Adolescent; Amino Acid Substitution; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Codon; Cytosine; DNA Mutational Analysis; Drug Resistance, Viral; Female; Foscarnet; Graft vs Host Disease; Herpes Simplex; Humans; Immunocompromised Host; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Point Mutation; Salvage Therapy; Simplexvirus; Thymidine Kinase; Transplantation, Homologous; Valacyclovir; Valine; Viral Proteins; Virus Activation	2001
Successful treatment of foscarnet-resistant herpes simplex stomatitis with intravenous cidofovir in a child. The Pediatric infectious disease journal, 2001, Volume: 20, Issue:11 Topics: Acyclovir; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Herpes Simplex; Herpesvirus 1, Human; Humans; Immunocompromised Host; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Stomatitis	2001
Multiple herpes simplex virus infections with various resistance patterns in a matched unrelated donor transplant recipient. Bone marrow transplantation, 2001, Volume: 28, Issue:8 Topics: Acyclovir; Antineoplastic Agents, Alkylating; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Combined Modality Therapy; Cyclosporine; Cytarabine; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Fatal Outcome; Foscarnet; Graft vs Host Disease; Herpes Genitalis; Herpes Simplex; Humans; Hydroxyurea; Immunocompromised Host; Immunosuppressive Agents; Interferons; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methotrexate; Middle Aged; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Transplantation Conditioning; Whole-Body Irradiation	2001
Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy. Journal of medical virology, 2002, Volume: 67, Issue:1 Topics: Adenine; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Foscarnet; Herpes Genitalis; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV Infections; Humans; Organophosphonates; Reverse Transcriptase Inhibitors	2002
Successful treatment of an aciclovir-resistant herpes simplex type 2 infection with cidofovir in an AIDS patient. The British journal of dermatology, 2002, Volume: 147, Issue:1 Topics: Acyclovir; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytosine; Drug Resistance, Viral; Female; Fissure in Ano; Herpes Simplex; Herpesvirus 2, Human; Humans; Organophosphonates; Organophosphorus Compounds	2002
Phosphonoacetic acid-resistant herpes simplex virus infection in hairless mice. Antimicrobial agents and chemotherapy, 1975, Volume: 7, Issue:3 Topics: Acetates; Animals; Antiviral Agents; Drug Resistance, Microbial; Herpes Simplex; Mice; Organophosphonates; Simplexvirus	1975
The activity of iododeoxyuridine, adenine arabinoside, cytosine arabinoside, ribavirin and phosphonoacetic acid against herpes virus in the hairless mouse model. The Journal of antimicrobial chemotherapy, 1977, Volume: 3 Suppl A Topics: Acetates; Animals; Cytarabine; Disease Models, Animal; Herpes Simplex; Idoxuridine; Kinetics; Mice; Mice, Nude; Organophosphonates; Ribavirin; Ribonucleosides; Simplexvirus; Vidarabine	1977
Chemotherapy of genital herpes simplex virus type 2 infections of female hamsters. Antimicrobial agents and chemotherapy, 1977, Volume: 11, Issue:4 Topics: Animals; Cell Line; Cricetinae; Cytarabine; Female; Herpes Simplex; Idoxuridine; Organophosphonates; Vaginal Diseases; Vidarabine	1977
Comparative effectiveness of six antiviral agents in Herpes simplex type 1 infection of mice. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 152, Issue:3 Topics: Animals; Antiviral Agents; Cytarabine; Drug Interactions; Female; Herpes Simplex; Idoxuridine; Interferons; Mice; Organophosphonates; Organophosphorus Compounds; Poly I-C; Vidarabine	1976
Phosphonomethylether compounds as antiviral agents. Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3 Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Haplorhini; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Structure-Activity Relationship	1991
Phosphonylmethoxyalkyl purine and pyrimidine derivatives for treatment of opportunistic cytomegalovirus and herpes simplex virus infections in murine AIDS. Antiviral research, 1991, Volume: 16, Issue:1 Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Ganciclovir; Herpes Simplex; Immune Tolerance; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Opportunistic Infections; Organophosphonates; Organophosphorus Compounds	1991
Prolonged and potent therapeutic and prophylactic effects of (S)-1-[(3-hydroxy-2-phosphonylmethoxy)propyl]cytosine against herpes simplex virus type 2 infections in mice. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:8 Topics: Animals; Antiviral Agents; Brain Stem; Cidofovir; Cytosine; Drug Administration Schedule; Encephalitis; Female; Ganciclovir; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Premedication	1991
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine in various models of herpes simplex virus infection in mice. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:4 Topics: Acyclovir; Animals; Antiviral Agents; Brain Diseases; Cidofovir; Cytosine; Herpes Simplex; Mice; Mice, Hairless; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Peritoneal Cavity; Skin Diseases, Infectious	1991
9-(2-Phosphonylmethoxyethyl)adenine in the treatment of murine acquired immunodeficiency disease and opportunistic herpes simplex virus infections. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:11 Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Antiviral Agents; Concanavalin A; Herpes Simplex; Interferons; Mice; Mice, Inbred C57BL; Mitogens; Opportunistic Infections; Organophosphonates; Spleen; Zidovudine	1989
Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo. Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:2 Topics: Adenine; Animals; Antiviral Agents; Brain Diseases; Herpes Simplex; Injections; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Mice, Hairless; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Vaccinia	1989
Intracellular phosphorylation of broad-spectrum anti-DNA virus agent (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and inhibition of viral DNA synthesis. Molecular pharmacology, 1987, Volume: 32, Issue:4 Topics: Adenine; Animals; Antiviral Agents; DNA, Viral; Herpes Simplex; Leukemia L1210; Organophosphonates; Organophosphorus Compounds; Phosphorylation; Simplexvirus; Tumor Cells, Cultured; Virus Replication	1987