Compounds > organophosphonates
Page last updated: 2024-09-05

organophosphonates and HIV

organophosphonates has been researched along with HIV in 137 studies

Research

Studies (137)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.19)18.7374
1990's26 (18.98)18.2507
2000's47 (34.31)29.6817
2010's61 (44.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaltashov, IA; Xu, S1
Naing, C; Poovorawan, Y; Tong, KS1
Adams, JL; Corbett, AH; Dumond, JB; Forrest, A; Jennings, SH; Kashuba, AD; Kendrick, RL; Malone, S; Patterson, KB; Prince, HM; Sykes, C; Wang, R; White, N1
Arnett, DK; Bagchi, S; Chi, BH; Heimburger, DC; Kabagambe, EK; Kiage, JN; Koethe, JR; Nyirenda, CK; Wellons, MF1
Bachman, S; Cong, ME; García-Lerma, JG; Hanson, DL; Heneine, W; Mitchell, J; Sweeney, E1
Charalambous, S; Churchyard, GJ; Grant, AD; Hoffmann, CJ; Lewis, JJ; Velen, K1
Bekker, LG; Kaplan, R; Lawn, SD; Njuguna, C; Orrell, C; Wood, R1
Casado, JL; Del Palacio, M; Moreno, A; Moreno, S; Safont, P; Wikman, P1
Amara, S; Carriere, F; Cazabat, M; Chapuy-Regaud, S; de Medina, P; Delton-Vandenbroucke, I; Izopet, J; Payre, B; Poirot, M; Record, M; Requena, M; Subra, C1
Andrei, G; Balestra, E; Balzarini, J; Holý, A; Huskens, D; Introini, A; Liekens, S; Margolis, L; Perno, CF; Schols, D; Snoeck, R; Vanpouille, C; Zicari, S1
Boyd, A; Brichler, S; Chevallier-Queyron, P; Delaugerre, C; Girard, PM; Gordien, E; Lacombe, K; Maylin, S; Miailhes, P; Scholtès, C1
Baker, A; Bethel, J; Flynn, PM; Gordon, CM; Havens, PL; Hazra, R; Kapogiannis, BG; Kiser, JJ; Liu, N; Lujan-Zilbermann, J; Mulligan, K; Pan, CG; Rutledge, B; Stephensen, CB; Van Loan, MD; Wilson, CM; Woodhouse, LR1
Dinh, CT; Hendry, RM; Herold, BC; Kiser, PF; Martin, A; McNicholl, JM; Mesquita, PM; Nagaraja, U; Rastogi, R; Smith, JM; Srinivasan, P; Teller, RS1
Bekker, LG; Kamkuemah, M; Kaplan, R; Myer, L1
Brooks, JT; Chirwa, LI; Henderson, FL; Johnson, JA; Li, JF; Matlhaba, O; Niska, RW; Paxton, LA; Rose, CE; Segolodi, TM; Thigpen, MC1
Balzarini, J; Flynn, ÁS; Hinsinger, K; McGuigan, C; Pertusati, F; Powell, N; Tristram, A1
Ayala-Sims, VA; Fulco, PP1
Barthe, Y; Bouix, C; Cacoub, P; Carrat, F; Lascoux-Combe, C; Lebossé, F; Maynard-Muet, M; Miailhes, P; Piroth, L; Pol, S; Rey, D; Sogni, P; Zoulim, F1
Debyser, Z; Schrijvers, R1
Arribas, JR; Di Perri, G; Ebrahimi, R; Gathe, J; Nguyen, T; Pialoux, G; Piontkowsky, D; Reynes, J; Tebas, P; White, K1
Antela, A; Domingo, P; Garner, W; Girard, PM; Guyer, B; Henry, K; Markowitz, M; Mills, A; Nguyen, T; Piontkowsky, D; Pozniak, A; Stellbrink, HJ; White, K1
Amiel, C; Chas, J; Guessant, S; Hamidi, M; Kherallah, K; Lebrette, MG; Lependeven, C; Pialoux, G; Schneider, V1
Carnovale, C; Chiacchio, MA; Giofrè, SV; Macchi, B; Monciino, G; Romeo, R; Sanfilippo, C1
Chi, BH; Emge, D; Mulenga, L; Mweemba, A; Vinikoor, MJ; Wandeler, G; Zanolini, A1
Dinh, C; Herold, BC; Kiser, P; Lo, Y; McNicholl, JM; Pau, CP; Smith, JM; Srinivasan, P; Teller, R; Zhang, J1
Back, DJ; Burger, D; Lamorde, M; Schapiro, JM1
Abdool Karim, SS; Eshleman, SH; Garrett, N; Karim, QA; Laeyendecker, O; Longosz, AF; Naranbhai, V; Nason, M; Quinn, TC; Redd, AD1
Bader, J; Glass, TR; Klimkait, T; Labhardt, ND; Lejone, TI; Puga, D; Ringera, I1
Dai, G; Herdewijn, P; Liu, F; Liu, FW; Liu, HM; Liu, Y; Pannecouque, C; Wang, Y; Xu, RG; Zhao, LX1
Aldern, KA; Beadle, JR; Broker, TR; Buckheit, RW; Chow, LT; Harden, EA; Hartman, T; Hostetler, KY; Keith, KA; Prichard, MN; Valiaeva, N; Yang, G; Yu, JH1
Barreiro, P; García-Samaniego, J; Martín-Carbonero, L1
Azanza, JR; García Quetglas, E; Gómez-Giu, A; Sádaba, B1
Fiorante, S; Pulido, F1
Arribas López, JR; Bernardino de la Serna, JI; Mora Rillo, M1
López Bernaldo de Quirós, JC1
Mallolas, J1
Boryski, J; Collu, G; Kraszewski, A; La Colla, P; Loddo, R; Romanowska, J; Sanna, G; Secci, B; Stawiński, J; Szymańska-Michalak, A1
Cheshenko, N; Fakioglu, E; Guzman, E; Herold, BC; Keller, MJ; Mesquita, PM; Mhatre, M; Wilson, SS1
Amuron, B; Birungi, J; Bunnell, R; Coutinho, A; Foster, S; Grosskurth, H; Jaffar, S; Kyomuhangi, R; Levin, J; Mermin, J; Nabiryo, C; Namara, G; Ndembi, N; Opio, A; Tappero, JW1
Airoldi, M; Cossarizza, A; De Biasi, S; Gibellini, L; Maggiolo, F; Mussini, C; Nasi, M; Pinti, M; Ravasio, V; Roat, E; Suter, F1
Herdewijn, P; Huang, Q1
Mohammadi, D1
Boucher, CA; van de Vijver, DA1
Murphy, B; Romanelli, F1
Hong, JH; Liu, LJ; Oh, CH1
Cerini, C; Fabiano, V; Giacomet, V; Mora, S; Pivetti, V; Puzzovio, M; Viganò, A; Zamproni, I; Zuccotti, GV1
Amico, KR; Anderson, PL; Bekker, LG; Buchbinder, SP; Burns, DN; Bushman, LR; Casapía, M; Chariyalertsak, S; Defechereux, P; Fernández, T; Ganoza, C; Glidden, DV; Goicochea, P; Grant, RM; Guanira-Carranza, JV; Hance, RJ; Jaffe, HS; Kallás, EG; Lama, JR; Lee, J; Liu, AY; Martinez, AI; Mayer, KH; McConnell, JJ; McMahan, V; Montoya-Herrera, O; Mulligan, K; Postle, B; Ramirez-Cardich, ME; Rooney, JF; Schechter, M; Vargas, L; Veloso, VG; Wang, F; Zheng, JH1
Hachiya, A; Kirby, KA; Kodama, EN; Michailidis, E; Oka, S; Sakagami, Y; Sarafianos, SG; Schuckmann, MM; Singh, K1
Aung, W; Cong, ME; Dobard, C; Garcia-Lerma, JG; Heneine, W; Mitchell, J; Sharma, S; Youngpairoj, AS1
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T1
Cong, ME; Curtis, KA; García-Lerma, JG; Hanson, D; Heneine, W; Kennedy, MS; Luckay, A; Owen, SM; Smith, J; Youngpairoj, AS; Zheng, Q1
Cotter, AG; Powderly, WG1
Andrei, G; Balzarini, J; Hocková, D; Holý, A; Snoeck, R1
Cocohoba, J; Gruta, C; John, MD; Lao, CK1
Budhathoki, C; Collier, AC; Daar, ES; Farajallah, A; Feinberg, J; Fischl, MA; Godfrey, C; Ha, B; Jahed, NC; Katzenstein, D; Mollan, K; Murphy, RL; Myers, L; Rooney, JF; Sax, PE; Tashima, K; Tierney, C; Woodward, WC1
Branger, M; Collin, G; Fraqueiro, G; Gervais, A; Hamet, G; Lada, O; Marcellin, P; Martinot-Peignoux, M; Matheron, S; Moucari, R; Peytavin, G; Roquebert, B1
Cellini, M; Gabiano, C; Giacomet, V; Manfredini, V; Mora, S; Puzzovio, M; Salvini, F; Stucchi, S; Tamburrini, E; Viganò, A; Zuccotti, GV1
Branger, M; Collin, G; Fraqueiro, G; Gervais, A; Lada, O; Leclerc, L; Marcellin, P; Martinot-Peignoux, M; Matheron, S; Moucari, R; Peytavin, G; Roquebert, B1
Kent, SJ1
Adams, JL; Kashuba, AD1
Aubron-Olivier, C; Calvez, V; Charpentier, C; Descamps, D; Katlama, C; Landman, R; Marcelin, AG; Simon, A; Valantin, MA; Wirden, M; Yeni, P1
Abdool Karim, SS; Baxter, C1
Herold, BC; Huber, AM; Kiser, PF; Mesquita, PM; Rastogi, R; Segarra, TJ; Teller, RS; Torres, NM1
De Clercq, E3
Baum, MM; Butkyavichene, I; Clark, MR; Friend, DR; Gilman, J; Kennedy, S; Kopin, E; Malone, AM; Moss, JA; Nguyen, C; Smith, TJ1
Bonovas, S; Hatzakis, A; Nikolopoulos, G; Tsiodras, S1
Ananworanich, J; Bhakeecheep, S; Bowonwatanuwong, C; Bunupuradah, T; Chetchotisakd, P; Hirschel, B; Jirajariyavej, S; Kantipong, P; Kerr, SJ; Klinbuayaem, V; Munsakul, W; Prasithsirikul, W; Ruxrungtham, K; Sophonphan, J; Sungkanuparph, S1
Breeze, S1
Armishaw, J; Cameron, PU; Chuah, J; Cooper, DA; Crowe, SM; Fairley, C; Gouillou, M; Hearps, A; Koelsch, KK; Leeansyah, E; Lewin, SR; Liu, JP; Pierce, AB; Smit, de V; Solomon, A; Spelman, T; Tennakoon, S; Velayudham, P1
Bakshi, KK; Chen, J; Condra, JH; Danovich, RM; DiNubile, MJ; Graham, DJ; Haas, DW; Holder, DJ; Rhodes, RR; Saah, AJ; Shivaprakash, M1
Aries, SP; Dalhoff, K; Kramme, E; Schaaf, B; Steinhoff, J1
Asensi, V; Barrios, A; Dalmau, D; de Mendoza, C; Domingo, P; Estrada, V; Galindo, MJ; Gálvez, J; Martín-Carbonero, L; Ribera, E; Soriano, V1
Camino, N; Núñez, M; Puoti, M; Soriano, V1
Benhamou, Y1
Acosta, EP; Brundage, RC; Fletcher, CV; Gulick, RM; Haubrich, R; Jiang, H; Katzenstein, D1
Ait-Khaled, M; Craig, C; Griffin, P; Stone, C; Tisdale, M1
Bates, M; Chappey, C; Clair, MS; Fisher, R; Lanier, ER; Parkin, N; Ross, L; Tisdale, M1
Havlir, DV; Ignacio, CC; Koelsch, KK; Lu, B; Margot, N; Miller, MD; Strain, MC; Wong, JK1
Busson, R; De Clercq, E; Froeyen, M; Herdewijn, P; Kempeneers, V; Pannecouque, C; Wang, J; Wu, T1
Claas, EC; Gelinck, LB; Kroon, FP1
Angel-Moreno-Maroto, A; Hernández-Cabrera, M; Pérez-Arellano, JL; Suárez-Castellano, L1
Cohen, J3
Boryski, J; Collu, G; Giliberti, G; Kraszewski, A; La Colla, P; Loddo, R; Sanna, G; Stawiński, J; Szymańska, A; Szymczak, M1
Thio, CL1
Arribas, JR; Campo, RE; Cheng, AK; Chuck, S; DeJesus, E; Enejosa, J; Gallant, JE; Gazzard, B; Lu, B; McColl, D; Pozniak, AL; Toole, JJ1
Arvieux, C; Dailly, E; Jolliet, P; Perré, P; Raffi, F; Tattevin, P; Tribut, O1
Jenny-Avital, ER1
Hussain, S; Khayat, A; Rathore, MH; Tolaymat, A1
Farthing, C; Khanlou, H1
Khandazhinskaya, A; Shirokova, E; Yasko, M1
Arnaiz, JA; Blanco, JL; de Lazzari, E; Garrabou, G; Gatell, JM; Laguno, M; Larrousse, M; Leon, A; Lonca, M; López, S; Mallolas, J; Martinez, E; Milinkovic, A; Miró, O; Vidal, S1
Babusis, D; Boojamra, CG; Chen, J; Cihlar, T; Douglas, J; Grant, D; Hui, HC; Kim, CU; Lin, KY; Mackman, RL; Markevitch, DY; Petrakovsky, O; Prasad, V; Ray, A; Vela, J; Zhang, L1
Chen, J; Cooper, DA; Emery, S; Hazuda, DJ; Kelleher, AD; Law, M; Murray, JM; Nguyen, BY; Teppler, H1
Ananworanich, J; Chetchotisakd, P; Hirschel, B; Jupimai, T; Klinbuayam, W; Mahanontharit, A; Nüesch, R; Prasithsirikul, W; Ruxrungtham, K; Srasuebkul, P1
Guillemi, S; Gutiérrez, S; Harrigan, PR; Jahnke, N; Montaner, JS; Montessori, V1
Gafni, RI; Hazra, R; Purdy, JB; Reynolds, JC; Zeichner, S1
Geretti, AM1
Balzarini, J; De Clercq, E; Debyser, Z; Desmyter, J; Holy, A; Jindrich, J; Rosenberg, I; Thormar, H1
Balzarini, J; De Clercq, E; Goebels, J; Hatse, S; Sobis, H; Vandeputte, M; Verstuyf, A1
Abushanab, E; El-Subbagh, HI; Panzica, RP; Racha, S; Vargeese, C; Vemishetti, P1
Aquaro, S; Balestra, E; Balzarini, J; Calio, R; Cenci, A; Di Pierro, D; Lazzarino, G; Panti, S; Perno, CF; Tavazzi, B1
Aquaro, S; Balestra, E; Balzarini, J; Caliò, R; Cenci, A; Francesconi, M; Panti, S; Perno, CF; Serra, F; Villani, N1
Bischofberger, N; Fridland, A; Kim, C; Robbins, BL; Srinivas, RV1
Fridland, A; Srinivas, RV1
Agatep, E; Berardi, CJ; Bischofberger, N; Cundy, KC; Dehqanzada, ZA; Lifson, JD; Marthas, ML; Pedersen, NC; Van Rompay, KK; Vasquez, GM1
Abbed, K; Boue, F; Delfraissy, JF; Dussaix, E; Gasnault, J; Goujard, C; Kousignian, P; Taoufik, Y1
Adriani, B; Beretta, R; Cargnel, A; Fasolo, MM; Orlando, G; Signori, R; Zanchetta, N1
Collier, AC; Schwartz, MA1
Self, SG; Wick, D1
Ammassari, A; Antinori, A; Cingolani, A; De Luca, A; Giancola, ML; Govoni, A; Grisetti, S; Monforte, AD; Murri, R; Paglia, MG; Testa, L1
Torres, G1
Delaney, WE; Locarnini, S; Shaw, T1
Gazzard, BG1
Balzarini, J; Bergamini, A; Calio, R; De Clercq, E; Milanese, G; Pauwels, R; Perno, CF; Rocchi, G; Yarchoan, R1
Hitchcock, MJ; Mansuri, MM; Martin, JC; Starrett, JE; Tortolani, DR1
Cohen, JS; Iversen, PL; Stec, WJ; Stein, A; Subasinghe, C; Zon, G1
Balzarini, J; De Clercq, E; Hao, Z; Herdewijn, P; Johns, DG1
Balzarini, J; De Clercq, E; Dvorakova, H; Hao, Z; Herdewijn, P; Holy, A; Jindrich, J; Johns, DG; Snoeck, R1
Broder, S; Kageyama, S; Mitsuya, H; Yarchoan, R1
Balzarini, J; DeClercq, E; Karamov, EV; Krayevsky, AA; Kuhanova, MK; Lukashov, VV; Tarussova, NB1
Classon, B; Ioannidis, P; Kvarnström, I; Samuelsson, B1
Daum, T; Engels, JW; Frauendorf, A; Lüking, S; Mag, M; Müller, WE; Muth, J; Rosmanitz, P1
Bronson, JJ; De Boeck, H; Ghazzouli, I; Hitchcock, MJ; Ho, HT; Martin, JC; Woods, K1
Balzarini, J; Borst, M; De Clercq, E; Egberink, H; Horzinek, M; Koolen, M; Neu, H; Niphuis, H; Schellekens, H1
Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P1
Baba, M; Balzarini, J; De Clercq, E; Desmyter, J; Holy, A; Pauwels, R; Rosenberg, I; Schols, D1
Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Holy, A; Johns, DG; Naesens, L; Pauwels, R; Rosenberg, I1

Reviews

23 review(s) available for organophosphonates and HIV

ArticleYear
Comparative effectiveness of anti-viral drugs with dual activity for treating hepatitis B and HIV co-infected patients: a network meta-analysis.
    BMC infectious diseases, 2018, Nov-14, Volume: 18, Issue:1

    Topics: Adenine; Adult; Aged; Antiviral Agents; Coinfection; Emtricitabine; Female; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Network Meta-Analysis; Organophosphonates; Tenofovir; Treatment Outcome; Young Adult

2018
Antiretroviral drugs for prevention of mother-to-child transmission: pharmacologic considerations for a public health approach.
    AIDS (London, England), 2014, Nov-13, Volume: 28, Issue:17

    Topics: Adenine; Adult; Alkynes; Anti-Retroviral Agents; Benzoxazines; Child; Cyclopropanes; Drug Resistance, Viral; Drug Therapy; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Lamivudine; Organophosphonates; Public Health; Tenofovir

2014
[Hepatitis B in patients with HIV infection].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Guanine; Hepatitis B; Hepatitis B Vaccines; Hepatitis B virus; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Nucleosides; Organophosphonates; Practice Guidelines as Topic; Pyrimidinones; Reverse Transcriptase Inhibitors; Telbivudine; Tenofovir; Thymidine; Virus Replication

2008
[Tenofovir: pharmacology and interactions].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Adolescent; Adult; Aged; Anti-HIV Agents; Biological Availability; Biotransformation; Child; Child, Preschool; Deoxyadenine Nucleotides; DNA, Viral; Drug Interactions; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Kidney Diseases; Liver Diseases; Middle Aged; Molecular Structure; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Virus Replication; Young Adult

2008
[Clinical data II. Clinical experience of tenofovir DF in combination with protease inhibitors].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Clinical Trials as Topic; Cohort Studies; Deoxycytidine; Diabetic Nephropathies; Double-Blind Method; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; Emtricitabine; HIV; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Kidney Diseases; Multicenter Studies as Topic; Organophosphonates; Randomized Controlled Trials as Topic; Retrospective Studies; Reverse Transcriptase Inhibitors; Salvage Therapy; Tenofovir; Treatment Outcome

2008
[Clinical data I. Clinical experience with tenofovir in combination with nonnucleoside analogue transcriptase inhibitors].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV; HIV Infections; HIV Protease Inhibitors; HIV Reverse Transcriptase; Humans; Multicenter Studies as Topic; Organophosphonates; Patient Acceptance of Health Care; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; Tenofovir; Treatment Outcome

2008
[Tenofovir DF in rescue regimens].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anti-HIV Agents; Antimetabolites; Clinical Trials, Phase III as Topic; Drug Resistance, Multiple, Viral; Drug Therapy, Combination; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Multicenter Studies as Topic; Mutation; Organophosphonates; Randomized Controlled Trials as Topic; Retrospective Studies; Reverse Transcriptase Inhibitors; Salvage Therapy; Selection, Genetic; Tenofovir; Thymidine; Treatment Failure; Viral Load; Zalcitabine

2008
The risk of HIV drug resistance following implementation of pre-exposure prophylaxis.
    Current opinion in infectious diseases, 2010, Volume: 23, Issue:6

    Topics: Adenine; Animals; Anti-HIV Agents; Deoxycytidine; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; HIV; HIV Infections; Humans; Organophosphonates; Risk Assessment; Tenofovir; Viremia

2010
Systemic preexposure prophylaxis for human immunodeficiency virus infection.
    Pharmacotherapy, 2010, Volume: 30, Issue:10

    Topics: Adenine; Animals; Anti-HIV Agents; Antiviral Agents; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Occupational Exposure; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Risk Factors; Risk-Taking; Tenofovir

2010
Endocrine complications of human immunodeficiency virus infection: hypogonadism, bone disease and tenofovir-related toxicity.
    Best practice & research. Clinical endocrinology & metabolism, 2011, Volume: 25, Issue:3

    Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Diseases; Endocrine System Diseases; HIV; HIV Infections; Humans; Hypogonadism; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir

2011
Formulation, pharmacokinetics and pharmacodynamics of topical microbicides.
    Best practice & research. Clinical obstetrics & gynaecology, 2012, Volume: 26, Issue:4

    Topics: Adenine; Animals; Anti-HIV Agents; Anti-Infective Agents, Local; Female; HIV; HIV Infections; Humans; Mice; Organophosphonates; Tenofovir; Treatment Outcome; Vaginal Creams, Foams, and Jellies

2012
Overview of microbicides for the prevention of human immunodeficiency virus.
    Best practice & research. Clinical obstetrics & gynaecology, 2012, Volume: 26, Issue:4

    Topics: Adenine; Anti-HIV Agents; Anti-Infective Agents; Clinical Trials as Topic; Female; HIV; HIV Infections; Humans; Organophosphonates; Tenofovir

2012
Tenofovir: quo vadis anno 2012 (where is it going in the year 2012)?
    Medicinal research reviews, 2012, Volume: 32, Issue:4

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Drug Combinations; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Tenofovir

2012
Antiretrovirals for HIV Exposure Prophylaxis.
    Current medicinal chemistry, 2012, Volume: 19, Issue:35

    Topics: Adenine; Anti-HIV Agents; Deoxycytidine; Dideoxynucleosides; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Occupational Exposure; Organophosphonates; Stavudine; Tenofovir; Zidovudine

2012
The synthesis and antiviral properties of acyclic nucleoside analogues with a phosphonomethoxy fragment in the side chain.
    Current medicinal chemistry, 2006, Volume: 13, Issue:24

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; Hepatitis B virus; HIV; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Prodrugs

2006
Resistance testing methodologies and mechanisms of resistance.
    Journal of HIV therapy, 2007, Volume: 12, Issue:4

    Topics: Adenine; Anti-HIV Agents; CCR5 Receptor Antagonists; Drug Resistance, Viral; HIV; Humans; Lopinavir; Nitriles; Organophosphonates; Pyridazines; Pyrimidines; Pyrimidinones; Tenofovir

2007
Inhibition of replication of HIV in primary monocyte/macrophages by different antiviral drugs and comparative efficacy in lymphocytes.
    Journal of leukocyte biology, 1997, Volume: 62, Issue:1

    Topics: Anti-HIV Agents; HIV; Humans; Lymphocytes; Macrophages; Monocytes; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Virus Replication

1997
Strategies for second-line antiretroviral therapy in adults with HIV infection.
    Advances in experimental medicine and biology, 1999, Volume: 458

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Dideoxynucleosides; Drug Therapy, Combination; HIV; HIV Infections; Humans; Organophosphonates; Oxazines; Reverse Transcriptase Inhibitors; Virus Latency; Virus Replication

1999
Resistance of hepatitis B virus to antiviral drugs: current aspects and directions for future investigation.
    Antiviral chemistry & chemotherapy, 2001, Volume: 12, Issue:1

    Topics: 2-Aminopurine; Adenine; Amino Acid Sequence; Animals; Anti-HIV Agents; Antimetabolites; Antiviral Agents; Biological Availability; Cell Line; Clinical Trials as Topic; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Viral; Drug Therapy, Combination; Enzyme Inhibitors; Famciclovir; Gene Products, pol; Hepatitis B; Hepatitis B virus; Hepatitis Viruses; Hepatitis, Animal; HIV; Humans; Lamivudine; Models, Animal; Molecular Sequence Data; Molecular Structure; Nucleosides; Organophosphonates; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Virus Replication

2001
The potential place of tenofovir in antiretroviral treatment regimens.
    International journal of clinical practice, 2001, Volume: 55, Issue:10

    Topics: Adenine; Anti-HIV Agents; Drug Resistance, Viral; HIV; HIV Infections; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir

2001
Targeted therapy of human immunodeficiency virus-related disease.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1991, Volume: 5, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Antiviral Agents; CD4 Antigens; Didanosine; Dideoxynucleosides; Dipyridamole; Drug Synergism; Gene Expression Regulation, Viral; Genes, nef; Genes, rev; Genes, tat; HIV; HIV Protease; Interferon Type I; Organophosphonates; RNA-Directed DNA Polymerase; Stavudine; Transcription, Genetic; Zalcitabine; Zidovudine

1991
Biochemical pharmacology of acyclic nucleotide analogues.
    Annals of the New York Academy of Sciences, 1990, Volume: 616

    Topics: Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytosine; HIV; Humans; Nucleotides; Organophosphonates; Organophosphorus Compounds

1990
New acquisitions in the development of anti-HIV agents.
    Antiviral research, 1989, Volume: 12, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Animals; Antiviral Agents; Dideoxynucleosides; Drug Design; HIV; Molecular Structure; Organophosphonates; Polysaccharides; Purines

1989

Trials

17 trial(s) available for organophosphonates and HIV

ArticleYear
Association of higher plasma vitamin D binding protein and lower free calcitriol levels with tenofovir disoproxil fumarate use and plasma and intracellular tenofovir pharmacokinetics: cause of a functional vitamin D deficiency?
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:11

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; Calcitriol; Calcium; Double-Blind Method; Female; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Glomerular Filtration Rate; HIV; HIV Infections; Humans; Hypophosphatemia; Male; Organophosphonates; Parathyroid Hormone; Phosphates; Reverse Transcriptase Inhibitors; Tenofovir; Vitamin D Deficiency; Vitamin D-Binding Protein

2013
Role of a 48-week pegylated interferon therapy in hepatitis B e antigen positive HIV-co-infected patients on cART including tenofovir: EMVIPEG study.
    Journal of hepatology, 2014, Volume: 61, Issue:4

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Antiviral Agents; CD4 Lymphocyte Count; Coinfection; Deoxycytidine; Drug Carriers; Emtricitabine; Female; Hepatitis B e Antigens; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Male; Middle Aged; Organophosphonates; Polyethylene Glycols; Recombinant Proteins; Tenofovir; Treatment Outcome; Viral Load

2014
Simplification to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of ritonavir-boosted protease inhibitor with emtricitabine and tenofovir in adults with virologically suppressed HIV (STRATEGY-PI): 48 week results o
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Protease Inhibitors; Quinolones; Ritonavir; Tenofovir; Thiazoles; Viral Load

2014
Switching to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of non-nucleoside reverse transcriptase inhibitor with emtricitabine and tenofovir in virologically suppressed adults with HIV (STRATEGY-NNRTI): 48 week r
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Quinolones; Reverse Transcriptase Inhibitors; Tenofovir; Thiazoles; Viral Load

2014
Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: a cluster-randomised equivalence trial.
    Lancet (London, England), 2009, Dec-19, Volume: 374, Issue:9707

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Community Health Services; Female; HIV; HIV Infections; Home Care Services; Humans; Lamivudine; Male; Nevirapine; Organophosphonates; Stavudine; Tenofovir; Uganda; Zidovudine

2009
Mitochondrial changes during D-drug-containing once-daily therapy in HIV-positive treatment-naive patients.
    Antiviral therapy, 2010, Volume: 15, Issue:1

    Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cross-Sectional Studies; Cyclopropanes; Didanosine; Dideoxynucleosides; DNA, Mitochondrial; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Mitochondria; Organophosphonates; Reverse Transcriptase Inhibitors; RNA; RNA, Mitochondrial; Tenofovir

2010
Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.
    The New England journal of medicine, 2010, Dec-30, Volume: 363, Issue:27

    Topics: Adenine; Administration, Oral; Adolescent; Adult; Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Follow-Up Studies; HIV; HIV Antibodies; HIV Infections; HIV Seropositivity; Homosexuality, Male; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Nausea; Organophosphonates; Patient Compliance; RNA, Viral; Tenofovir; Transsexualism; Young Adult

2010
Abacavir/lamivudine versus tenofovir DF/emtricitabine as part of combination regimens for initial treatment of HIV: final results.
    The Journal of infectious diseases, 2011, Oct-15, Volume: 204, Issue:8

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Deoxycytidine; Dideoxynucleosides; Double-Blind Method; Emtricitabine; Female; HIV; HIV Infections; Humans; Kaplan-Meier Estimate; Lamivudine; Male; Middle Aged; Organophosphonates; RNA, Viral; Tenofovir; Viral Load

2011
A randomized comparison of second-line lopinavir/ritonavir monotherapy versus tenofovir/lamivudine/lopinavir/ritonavir in patients failing NNRTI regimens: the HIV STAR study.
    Antiviral therapy, 2012, Volume: 17, Issue:7

    Topics: Adenine; Adult; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Lopinavir; Male; Organophosphonates; Ritonavir; Tenofovir

2012
Treatment with indinavir, efavirenz, and adefovir after failure of nelfinavir therapy.
    The Journal of infectious diseases, 2003, Apr-01, Volume: 187, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Resistance, Viral; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Indinavir; Male; Middle Aged; Nelfinavir; Organophosphonates; Oxazines; Treatment Failure

2003
Sex-based differences in saquinavir pharmacology and virologic response in AIDS Clinical Trials Group Study 359.
    The Journal of infectious diseases, 2004, Apr-01, Volume: 189, Issue:7

    Topics: Adenine; Adult; Anti-HIV Agents; Delavirdine; Double-Blind Method; Drug Therapy, Combination; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Nelfinavir; Organophosphonates; Ritonavir; RNA, Viral; Saquinavir; Sex Factors

2004
Tenofovir DF, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV.
    The New England journal of medicine, 2006, Jan-19, Volume: 354, Issue:3

    Topics: Adenine; Adolescent; Adult; Aged; Alkynes; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cyclopropanes; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Organophosphonates; Oxazines; Prospective Studies; RNA, Viral; Tenofovir; Zidovudine

2006
The impact of reducing stavudine dose versus switching to tenofovir on plasma lipids, body composition and mitochondrial function in HIV-infected patients.
    Antiviral therapy, 2007, Volume: 12, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Body Composition; Cholesterol; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Lipodystrophy; Male; Middle Aged; Mitochondria; Organophosphonates; Oxygen Consumption; Stavudine; Tenofovir; Treatment Outcome; Triglycerides

2007
Antiretroviral therapy with the integrase inhibitor raltegravir alters decay kinetics of HIV, significantly reducing the second phase.
    AIDS (London, England), 2007, Nov-12, Volume: 21, Issue:17

    Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Administration Schedule; Drug Therapy, Combination; HIV; HIV Infections; HIV Integrase Inhibitors; Humans; Lamivudine; Linear Models; Organic Chemicals; Organophosphonates; Pyrrolidinones; Raltegravir Potassium; RNA, Viral; Statistics, Nonparametric; Tenofovir; Time Factors; Viral Load; Virus Integration; Virus Latency; Virus Replication

2007
Interruptions of tenofovir/emtricitabine-based antiretroviral therapy in patients with HIV/hepatitis B virus co-infection.
    AIDS (London, England), 2008, Jan-02, Volume: 22, Issue:1

    Topics: Adenine; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Deoxycytidine; Drug Administration Schedule; Emtricitabine; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Male; Organophosphonates; Tenofovir; Thailand; Transaminases; Treatment Outcome; Viral Load

2008
Cidofovir added to HAART improves virological and clinical outcome in AIDS-associated progressive multifocal leukoencephalopathy.
    AIDS (London, England), 2000, Sep-29, Volume: 14, Issue:14

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cerebrospinal Fluid; Cidofovir; Cytosine; DNA, Viral; Drug Therapy, Combination; Female; HIV; HIV Infections; HIV Seropositivity; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Proteinuria; RNA, Viral; Treatment Outcome

2000
Opportunistic infection highlights from the 35th ICAAC.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:10

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Antiviral Agents; Bacterial Vaccines; CD4 Lymphocyte Count; Cidofovir; Clinical Trials as Topic; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Ganciclovir; HIV; Humans; Influenza Vaccines; Mycobacterium avium-intracellulare Infection; Organophosphonates; Organophosphorus Compounds; Pneumonia; Pneumonia, Pneumocystis; Randomized Controlled Trials as Topic; United States; Valacyclovir; Valine; Viremia

1995

Other Studies

97 other study(ies) available for organophosphonates and HIV

ArticleYear
Overcoming the Hydrolytic Lability of a Reaction Intermediate in Production of Protein/Drug Conjugates: Conjugation of an Acyclic Nucleoside Phosphonate to a Model Carrier Protein.
    Molecular pharmaceutics, 2017, 08-07, Volume: 14, Issue:8

    Topics: Adenine; Chromatography, Ion Exchange; Chromatography, Liquid; Cidofovir; Cytosine; HIV; Nucleosides; Organophosphonates; Pharmaceutical Preparations; Protein Binding; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tenofovir

2017
Pharmacokinetics of two common antiretroviral regimens in older HIV-infected patients: a pilot study.
    HIV medicine, 2013, Volume: 14, Issue:7

    Topics: Adenine; Aged; Alkynes; Anti-HIV Agents; Atazanavir Sulfate; Benzoxazines; Black or African American; Cyclopropanes; Data Interpretation, Statistical; Deoxycytidine; Emtricitabine; Female; Frail Elderly; HIV; HIV Infections; Humans; Male; Middle Aged; Oligopeptides; Organophosphonates; Pilot Projects; Pyridines; Ritonavir; Tenofovir; White People

2013
Cardiometabolic risk factors among HIV patients on antiretroviral therapy.
    Lipids in health and disease, 2013, Apr-10, Volume: 12

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cardiovascular Diseases; Cholesterol, HDL; Cholesterol, LDL; Cyclopropanes; Female; HIV; HIV Infections; Humans; Insulin Resistance; Lamivudine; Male; Middle Aged; Nevirapine; Organophosphonates; Risk Factors; Stavudine; Tenofovir; Triglycerides; Zambia; Zidovudine

2013
Prophylactic efficacy of oral emtricitabine and tenofovir disoproxil fumarate combination therapy against a tenofovir-resistant simian/human immunodeficiency virus containing the K65R mutation in macaques.
    The Journal of infectious diseases, 2013, Aug-01, Volume: 208, Issue:3

    Topics: Adenine; Administration, Oral; Animals; Anti-HIV Agents; Deoxycytidine; Disease Transmission, Infectious; Drug Resistance, Viral; Emtricitabine; HIV; Macaca; Mutation, Missense; Organophosphonates; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Treatment Outcome

2013
Comparison of tenofovir, zidovudine, or stavudine as part of first-line antiretroviral therapy in a resource-limited-setting: a cohort study.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenine; Adolescent; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cohort Studies; Female; Health Resources; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Residence Characteristics; RNA, Viral; Stavudine; Tenofovir; Young Adult; Zidovudine

2013
Rates of switching antiretroviral drugs in a primary care service in South Africa before and after introduction of tenofovir.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenine; Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; Cohort Studies; Drug Substitution; Drug-Related Side Effects and Adverse Reactions; Female; HIV; HIV Infections; Humans; Male; Organophosphonates; Primary Health Care; Retrospective Studies; Risk Factors; South Africa; Tenofovir

2013
The significance of antiretroviral-associated acute kidney injury in a cohort of ambulatory human immunodeficiency virus-infected patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2013, Volume: 28, Issue:8

    Topics: Acute Kidney Injury; Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Female; Follow-Up Studies; Glomerular Filtration Rate; HIV; HIV Infections; Humans; Kidney Function Tests; Male; Organophosphonates; Prognosis; Prospective Studies; Risk Factors; Tenofovir

2013
Progesterone and a phospholipase inhibitor increase the endosomal bis(monoacylglycero)phosphate content and block HIV viral particle intercellular transmission.
    Biochimie, 2013, Volume: 95, Issue:9

    Topics: Androstenes; Arachidonic Acids; Cell Line; Cell Membrane; Cholesterol; Endosomes; Enzyme Inhibitors; HIV; Humans; Lipase; Lysophospholipids; Macrophages; Monocytes; Monoglycerides; Organophosphonates; Phospholipases; Pinocytosis; Progesterone; Virion; Virus Replication

2013
A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity.
    PLoS pathogens, 2013, Volume: 9, Issue:7

    Topics: Animals; Anti-HIV Agents; Antiviral Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV; Humans; Immunologic Factors; Leukocytes, Mononuclear; Lymphoid Tissue; Mice; Mice, Hairless; Mice, Nude; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Prodrugs; Pyrimidines; Reverse Transcriptase Inhibitors; Tissue Culture Techniques

2013
Effect of tenofovir with and without interferon on hepatitis D virus replication in HIV-hepatitis B virus-hepatitis D virus-infected patients.
    AIDS research and human retroviruses, 2013, Volume: 29, Issue:12

    Topics: Adenine; Adult; Female; Hepatitis B virus; Hepatitis Delta Virus; HIV; HIV Infections; Humans; Interferons; Limit of Detection; Male; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Virus Replication

2013
Intravaginal ring eluting tenofovir disoproxil fumarate completely protects macaques from multiple vaginal simian-HIV challenges.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-01, Volume: 110, Issue:40

    Topics: Adenine; Administration, Intravaginal; Animals; Delayed-Action Preparations; Drug Delivery Systems; Female; HIV; Lentivirus Infections; Macaca mulatta; Organophosphonates; Simian Immunodeficiency Virus; Tenofovir

2013
Low prevalence of renal dysfunction in HIV-infected pregnant women: implications for guidelines for the prevention of mother-to-child transmission of HIV.
    Tropical medicine & international health : TM & IH, 2013, Volume: 18, Issue:11

    Topics: Adenine; Adult; Age Factors; Anti-HIV Agents; CD4 Lymphocyte Count; Contraindications; Creatinine; Female; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Kidney Diseases; Male; Mothers; Organophosphonates; Pregnancy; Pregnancy Complications; Pregnancy Complications, Infectious; Pregnant Women; Prevalence; South Africa; Tenofovir; Viral Load

2013
CD4(+) cell count, viral load, and drug resistance patterns among heterosexual breakthrough HIV infections in a study of oral preexposure prophylaxis.
    AIDS (London, England), 2014, Jan-14, Volume: 28, Issue:2

    Topics: Adenine; Anti-HIV Agents; Botswana; CD4 Lymphocyte Count; Chemoprevention; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Heterosexuality; HIV; HIV Infections; Humans; Organophosphonates; Plasma; Post-Exposure Prophylaxis; Tenofovir; Viral Load

2014
PMPA and PMEA prodrugs for the treatment of HIV infections and human papillomavirus (HPV) associated neoplasia and cancer.
    European journal of medicinal chemistry, 2014, May-06, Volume: 78

    Topics: Adenine; Antineoplastic Agents; Antiviral Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; HIV; HIV Infections; Humans; Microbial Sensitivity Tests; Molecular Structure; Organophosphonates; Papillomavirus Infections; Prodrugs; Structure-Activity Relationship; Tenofovir; Tumor Cells, Cultured

2014
Sustained virological response after taking crushed elvitegravir-cobicistat-emtricitabine-tenofovir tablets.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2014, May-15, Volume: 71, Issue:10

    Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Carbamates; Cobicistat; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Organophosphonates; Powders; Quinolones; Tablets; Tenofovir; Thiazoles; Viral Load

2014
Switching STRATEGIES in HIV treatment.
    The Lancet. Infectious diseases, 2014, Volume: 14, Issue:7

    Topics: Adenine; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Male; Organophosphonates; Protease Inhibitors; Quinolones; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; Thiazoles

2014
Initiation of rilpivirine, tenofovir and emtricitabine (RPV/TDF/FTC) regimen in 363 patients with virological vigilance assessment in 'real life'.
    The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:12

    Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Genotype; HIV; HIV Infections; Humans; Microbial Sensitivity Tests; Nitriles; Organophosphonates; Pyrimidines; Rilpivirine; Tenofovir

2014
Enantiomerically pure phosphonated carbocyclic 2'-oxa-3'-azanucleosides: synthesis and biological evaluation.
    Molecules (Basel, Switzerland), 2014, Sep-12, Volume: 19, Issue:9

    Topics: HIV; HIV Infections; Humans; Molecular Structure; Nucleosides; Organophosphonates; Stereoisomerism; Structure-Activity Relationship; U937 Cells

2014
Chronic hepatitis B virus coinfection is associated with renal impairment among Zambian HIV-infected adults.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Dec-15, Volume: 59, Issue:12

    Topics: Adenine; Adolescent; Adult; Africa; Anti-HIV Agents; Coinfection; Female; Glomerular Filtration Rate; Hepatitis B, Chronic; HIV; Humans; Male; Middle Aged; Organophosphonates; Renal Insufficiency; Tenofovir; Young Adult

2014
Pharmacokinetic evaluation of tenofovir disoproxil fumarate released from an intravaginal ring in pigtailed macaques after 6 months of continuous use.
    Journal of medical primatology, 2014, Volume: 43, Issue:5

    Topics: Adenine; Administration, Intravaginal; Animals; Anti-HIV Agents; Drug Delivery Systems; Female; HIV; Lentivirus Infections; Macaca nemestrina; Organophosphonates; Simian Immunodeficiency Virus; Tenofovir; Time Factors; Vagina

2014
Antibody Maturation in Women Who Acquire HIV Infection While Using Antiretroviral Preexposure Prophylaxis.
    The Journal of infectious diseases, 2015, Sep-01, Volume: 212, Issue:5

    Topics: Adenine; Adult; Anti-Retroviral Agents; Antibody Affinity; Cohort Studies; Female; HIV; HIV Antibodies; HIV Infections; Humans; Immunoassay; Organophosphonates; Pre-Exposure Prophylaxis; Randomized Controlled Trials as Topic; Tenofovir; Time Factors; Young Adult

2015
Is zidovudine first-line therapy virologically comparable to tenofovir in resource-limited settings?
    Tropical medicine & international health : TM & IH, 2015, Volume: 20, Issue:7

    Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Cross-Sectional Studies; Cyclopropanes; Female; Health Resources; HIV; HIV Infections; Humans; Lamivudine; Lesotho; Logistic Models; Male; Middle Aged; Organophosphonates; Tenofovir; Viral Load; Zidovudine

2015
Synthesis and in vitro antiviral activities of [(dihydrofuran-2-yl)oxy]methyl-phosphonate nucleosides with 2-substituted adenine as base.
    Chemistry & biodiversity, 2015, Volume: 12, Issue:5

    Topics: Adenine; Antiviral Agents; Diarrhea Viruses, Bovine Viral; Dose-Response Relationship, Drug; Hepatitis B virus; HIV; Microbial Sensitivity Tests; Molecular Structure; Organophosphonates; Purine Nucleosides

2015
Synthesis and Antiviral Evaluation of Octadecyloxyethyl Benzyl 9-[(2-Phosphonomethoxy)ethyl]guanine (ODE-Bn-PMEG), a Potent Inhibitor of Transient HPV DNA Amplification.
    Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23

    Topics: Antiviral Agents; Cell Line, Tumor; DNA, Viral; Dose-Response Relationship, Drug; Guanine; HEK293 Cells; Herpesvirus 2, Human; HIV; Humans; Leukocytes, Mononuclear; Molecular Structure; Nucleic Acid Amplification Techniques; Organophosphonates; Papillomaviridae; Structure-Activity Relationship; Virus Replication

2016
[Conclusions. Tenofovir].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anti-HIV Agents; Drug Resistance, Viral; HIV; HIV Infections; HIV Reverse Transcriptase; Humans; Kidney Diseases; Liver Diseases; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir

2008
Aryl nucleoside H-phosphonates. Part 16: synthesis and anti-HIV-1 activity of di-aryl nucleoside phosphotriesters.
    Bioorganic & medicinal chemistry, 2009, May-01, Volume: 17, Issue:9

    Topics: Anti-HIV Agents; Cell Line; Cells, Cultured; HIV; Humans; Hydroxy Acids; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Nucleotides; Organophosphonates; Virus Replication

2009
Disruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safety.
    The Journal of infectious diseases, 2009, Aug-15, Volume: 200, Issue:4

    Topics: Adenine; Anti-HIV Agents; Anti-Infective Agents; Cell Line; Cellulose; Electric Impedance; Epithelial Cells; HIV; Humans; Inflammation; Naphthalenesulfonates; NF-kappa B; Organophosphonates; Polymers; Tenofovir; Tight Junctions; Virus Replication

2009
Synthesis of 3'-o-phosphonoethyl nucleosides with an adenine and a thymine base moiety.
    Nucleosides, nucleotides & nucleic acids, 2009, Volume: 28, Issue:5

    Topics: Adenine; Antiviral Agents; Cell Line; Cell Survival; Hepacivirus; HIV; Humans; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Thymine

2009
Findings in humanized-mouse model suggest benefit of further studies in HIV pre-exposure prophylaxis.
    Expert review of clinical immunology, 2010, Volume: 6, Issue:2

    Topics: Adenine; Animals; Anti-HIV Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Deoxycytidine; Disease Models, Animal; Drug Combinations; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Antibodies; HIV Infections; Humans; Infection Control; Liver Transplantation; Mice; Occupational Exposure; Organophosphonates; Organophosphorus Compounds; Tenofovir; Thymus Gland; Transplantation Chimera

2010
Trial results finally show potential for microbicidal HIV gel.
    The Lancet. Infectious diseases, 2010, Volume: 10, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Female; Gels; HIV; HIV Infections; Humans; Organophosphonates; South Africa; Tenofovir; Vagina

2010
Design and synthesis of dually branched 5'-norcarbocyclic adenosine phosphonodiester analogue as a new anti-HIV prodrug.
    Nucleosides, nucleotides & nucleic acids, 2010, Volume: 29, Issue:10

    Topics: Adenosine; Anti-HIV Agents; Cell Line; Drug Design; Drug Stability; HIV; Organophosphonates; Prodrugs

2010
Tenofovir disoproxil fumarate and bone mineral density: a 60-month longitudinal study in a cohort of HIV-infected youths.
    Antiviral therapy, 2010, Volume: 15, Issue:7

    Topics: Adenine; Adolescent; Antiretroviral Therapy, Highly Active; Biomarkers; Bone Density; Child; Child, Preschool; Collagen Type I; Female; Follow-Up Studies; HIV; HIV Infections; Humans; Longitudinal Studies; Male; Organophosphonates; Peptides; Tenofovir; Young Adult

2010
K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism.
    PloS one, 2011, Jan-13, Volume: 6, Issue:1

    Topics: Adenine; Catalytic Domain; Computer Simulation; Drug Resistance, Viral; HIV; HIV Reverse Transcriptase; Humans; Hydrogen Bonding; Kinetics; Mutation, Missense; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir

2011
Generation and mucosal transmissibility of emtricitabine- and tenofovir-resistant SHIV162P3 mutants in macaques.
    Virology, 2011, Apr-10, Volume: 412, Issue:2

    Topics: Adenine; Animals; Anti-HIV Agents; Deoxycytidine; Disease Models, Animal; Drug Resistance, Viral; Emtricitabine; HIV; Humans; Macaca; Mutation; Organophosphonates; Recombination, Genetic; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Virus Cultivation

2011
New prodrugs of Adefovir and Cidofovir.
    Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11

    Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus

2011
Delayed maturation of antibody avidity but not seroconversion in rhesus macaques infected with simian HIV during oral pre-exposure prophylaxis.
    Journal of acquired immune deficiency syndromes (1999), 2011, Aug-15, Volume: 57, Issue:5

    Topics: Adenine; Administration, Oral; Animals; Anti-HIV Agents; Antibodies, Viral; Antibody Affinity; Deoxycytidine; Drug Combinations; Emtricitabine; HIV; HIV Antibodies; Human Immunodeficiency Virus Proteins; Macaca mulatta; Organophosphonates; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Viral Load

2011
Acyclic nucleoside phosphonates with a branched 2-(2-phosphonoethoxy)ethyl chain: efficient synthesis and antiviral activity.
    Bioorganic & medicinal chemistry, 2011, Aug-01, Volume: 19, Issue:15

    Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Herpes Simplex; HIV; HIV Infections; Humans; Mice; Nucleosides; Organophosphonates; Simplexvirus; Structure-Activity Relationship; Vaccinia; Vaccinia virus; Virus Diseases; Viruses

2011
A comparison of tenofovir-associated renal function changes in HIV-infected African Americans vs Caucasians.
    Journal of the National Medical Association, 2011, Volume: 103, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Black or African American; Creatinine; Drug Monitoring; Female; Glomerular Filtration Rate; HIV; HIV Infections; Humans; Kidney; Male; Middle Aged; Organophosphonates; Renal Insufficiency; Tenofovir; United States; White People; Withholding Treatment

2011
Long-term outcome of primary non-responders to tenofovir therapy in HIV/HBV-co-infected patients: impact of HBV genotype G.
    Liver international : official journal of the International Association for the Study of the Liver, 2012, Volume: 32, Issue:1

    Topics: Adenine; Adult; Anti-HIV Agents; Coinfection; Deoxycytidine; DNA Mutational Analysis; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Emtricitabine; Female; Genotype; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Retrospective Studies; Tenofovir; Time Factors; Treatment Outcome

2012
In utero exposure to tenofovir disoproxil fumarate does not impair growth and bone health in HIV-uninfected children born to HIV-infected mothers.
    Antiviral therapy, 2011, Volume: 16, Issue:8

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone and Bones; Child; Child, Preschool; Cohort Studies; Cross-Sectional Studies; Female; Fetus; HIV; HIV Infections; HIV Seropositivity; Humans; Infant; Infectious Disease Transmission, Vertical; Italy; Male; Observation; Organophosphonates; Pregnancy; Reverse Transcriptase Inhibitors; Tenofovir

2011
Quasispecies analysis and in vitro susceptibility of HBV strains isolated from HIV-HBV-coinfected patients with delayed response to tenofovir.
    Antiviral therapy, 2012, Volume: 17, Issue:1

    Topics: Adenine; Adult; Antiviral Agents; Cloning, Molecular; Coinfection; DNA, Viral; Drug Resistance, Viral; Female; Genotype; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Mutation; Organophosphonates; Sequence Analysis, DNA; Tenofovir; Transfection

2012
Loss of control of HIV viremia associated with the fat malabsorption drug orlistat.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:9

    Topics: Adenine; Adult; Anti-HIV Agents; Anti-Obesity Agents; Deoxycytidine; Drug Combinations; Drug Interactions; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Seropositivity; Humans; Lactones; Male; Nonprescription Drugs; Obesity; Organophosphonates; Orlistat; Oxazines; Reverse Transcriptase Inhibitors; RNA, Viral; Viral Load

2012
Resistance profiles of emtricitabine and lamivudine in tenofovir-containing regimens.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:6

    Topics: Adenine; Adult; Anti-HIV Agents; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; Female; France; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Mutation, Missense; Organophosphonates; Retrospective Studies; RNA, Viral; Selection, Genetic; Tenofovir; Treatment Failure; Viral Load

2012
Intravaginal ring delivery of tenofovir disoproxil fumarate for prevention of HIV and herpes simplex virus infection.
    The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:7

    Topics: Adenine; Antiviral Agents; Cell Culture Techniques; Chemoprevention; Contraceptive Devices, Female; Female; Herpes Genitalis; HIV; HIV Infections; Humans; Organ Culture Techniques; Organophosphonates; Simplexvirus; Tenofovir

2012
An intravaginal ring for the simultaneous delivery of multiple drugs.
    Journal of pharmaceutical sciences, 2012, Volume: 101, Issue:8

    Topics: Acyclovir; Adenine; Administration, Intravaginal; Animals; Antiviral Agents; Delayed-Action Preparations; Drug Delivery Systems; Equipment Design; Female; HIV; HIV Infections; Humans; Organophosphonates; Reverse Transcriptase Inhibitors; Silicon; Tenofovir; Tensile Strength

2012
A 4-drug combination (Stribild) for HIV.
    The Medical letter on drugs and therapeutics, 2012, Nov-26, Volume: 54, Issue:1404

    Topics: Adenine; Anti-HIV Agents; Carbamates; Clinical Trials as Topic; Cobicistat; Deoxycytidine; Double-Blind Method; Drug Approval; Drug Combinations; Drug Interactions; Drug Resistance, Multiple, Viral; Emtricitabine; HIV; HIV Infections; Humans; Organophosphonates; Quinolones; Randomized Controlled Trials as Topic; Tenofovir; Thiazoles; United States; United States Food and Drug Administration

2012
Novel HIV-1 treatment Stribild™ gains regulatory approval.
    Expert review of clinical pharmacology, 2012, Volume: 5, Issue:6

    Topics: Adenine; Anti-HIV Agents; Carbamates; Deoxycytidine; Drug Approval; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Infections; Humans; Organophosphonates; Quinolones; Thiazoles

2012
Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging.
    The Journal of infectious diseases, 2013, Volume: 207, Issue:7

    Topics: Adenine; Adult; Aging; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Case-Control Studies; Cells, Cultured; Deoxycytidine; Dideoxynucleosides; Emtricitabine; Enzyme Activation; Female; HIV; HIV Infections; Humans; Lamivudine; Leukocytes, Mononuclear; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Regression Analysis; Reverse Transcriptase Inhibitors; Risk Factors; Telomerase; Telomere; Telomere Shortening; Tenofovir; Time Factors; Young Adult; Zidovudine

2013
Tenofovir helps beat hepatitis B.
    TreatmentUpdate, 2003, Volume: 15, Issue:1

    Topics: Adenine; Antiviral Agents; CD4 Lymphocyte Count; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Male; Organophosphonates; Organophosphorus Compounds; Tenofovir; Viral Load

2003
[Tenofovir (Viread)].
    SIDAhora : un proyecto del Departamento de Publicaciones del PWA Coalition, NY, 2002, Issue:1

    Topics: Adenine; Anti-HIV Agents; Drug Interactions; Drug Resistance, Viral; HIV; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir

2002
Acute renal failure associated with tenofovir treatment in a patient with acquired immunodeficiency syndrome.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Aug-01, Volume: 37, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adenine; Anti-HIV Agents; HIV; Humans; Kidney Tubular Necrosis, Acute; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Tenofovir; Viral Load

2003
Role of baseline human immunodeficiency virus genotype as a predictor of viral response to tenofovir in heavily pretreated patients.
    Journal of clinical microbiology, 2003, Volume: 41, Issue:9

    Topics: Adenine; Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Female; HIV; HIV Infections; Humans; Male; Organophosphonates; Organophosphorus Compounds; RNA, Viral; Tenofovir

2003
Treatment of chronic hepatitis B in the human immunodeficiency virus-infected patient: present and future.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, Dec-15, Volume: 37, Issue:12

    Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Forecasting; Hepatitis B, Chronic; HIV; HIV Infections; Humans; Interferon-alpha; Lamivudine; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir

2003
Antiretroviral therapy and HIV/hepatitis B virus coinfection.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, Mar-01, Volume: 38 Suppl 2

    Topics: Adenine; Antiretroviral Therapy, Highly Active; Antiviral Agents; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Lamivudine; Organophosphonates; Organophosphorus Compounds; Tenofovir

2004
Human immunodeficiency virus type 1 reverse transcriptase mutation selection during in vitro exposure to tenofovir alone or combined with abacavir or lamivudine.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:4

    Topics: Adenine; Anti-HIV Agents; Cloning, Molecular; Dideoxynucleosides; Drug Combinations; Drug Resistance, Viral; Genotype; HIV; HIV Reverse Transcriptase; Humans; Lamivudine; Mutation; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir

2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance.
    AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12

    Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resistance, Multiple, Viral; HIV; HIV Infections; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phenotype; Reverse Transcriptase Inhibitors; Stavudine; Tenofovir; Thymidine; Zalcitabine; Zidovudine

2004
Predictors of residual viremia in HIV-infected patients successfully treated with efavirenz and lamivudine plus either tenofovir or stavudine.
    The Journal of infectious diseases, 2005, Apr-01, Volume: 191, Issue:7

    Topics: Adenine; Adolescent; Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; Cyclopropanes; DNA, Viral; Female; HIV; HIV Infections; Humans; Lamivudine; Male; Middle Aged; Multivariate Analysis; Organophosphonates; Oxazines; RNA, Viral; Stavudine; Tenofovir; Viremia

2005
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents.
    Journal of the American Chemical Society, 2005, Apr-13, Volume: 127, Issue:14

    Topics: Anti-HIV Agents; DNA; DNA Polymerase I; HIV; Humans; Kinetics; Models, Molecular; Nucleosides; Organophosphonates; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Tetroses

2005
The risk of adefovir monotherapy in human immunodeficiency virus (HIV) and hepatitis B virus (HBV) co-infected patients.
    Journal of hepatology, 2005, Volume: 43, Issue:2

    Topics: Adenine; Antiviral Agents; DNA, Viral; Hepatitis B; Hepatitis B virus; HIV; HIV Infections; Humans; Organophosphonates; Treatment Outcome

2005
Severe efavirenz-induced hypersensitivity syndrome (not-DRESS) with acute renal failure.
    The Journal of infection, 2006, Volume: 52, Issue:2

    Topics: Acute Kidney Injury; Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Hypersensitivity; Ghana; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Lamivudine; Male; Mycobacterium tuberculosis; Organophosphonates; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; Tuberculosis

2006
HIV/AIDS. Prevention cocktails: combining tools to Stop HIV's spread.
    Science (New York, N.Y.), 2005, Aug-12, Volume: 309, Issue:5737

    Topics: Acyclovir; Adenine; Anti-HIV Agents; Antidepressive Agents, Second-Generation; Antiviral Agents; Bupropion; Circumcision, Male; Clinical Trials as Topic; Contraceptive Devices, Female; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV; HIV Infections; Humans; Hygiene; Male; Organophosphonates; Sexual Behavior; Tenofovir; Viral Load

2005
Aryl nucleoside H-phosphonates. Part 15: Synthesis, properties and, anti-HIV activity of aryl nucleoside 5'-alpha-hydroxyphosphonates.
    Bioorganic & medicinal chemistry, 2006, Mar-15, Volume: 14, Issue:6

    Topics: Anti-HIV Agents; Cell Line; Cells, Cultured; HIV; Humans; Hydroxy Acids; Microbial Sensitivity Tests; Molecular Structure; Organophosphonates; Virus Replication; Zidovudine

2006
Treatment of lamivudine-resistant hepatitis B in HIV-infected persons: is adefovir dipivoxil the answer?
    Journal of hepatology, 2006, Volume: 44, Issue:1

    Topics: Adenine; AIDS-Related Opportunistic Infections; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Hepatitis B Antibodies; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Antibodies; Humans; Lamivudine; Organophosphonates; Treatment Outcome

2006
Influence of tenofovir, nevirapine and efavirenz on ritonavir-boosted atazanavir pharmacokinetics in HIV-infected patients.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:7

    Topics: Adenine; Adult; Alkynes; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Cyclopropanes; Drug Interactions; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Male; Nevirapine; Oligopeptides; Organophosphonates; Oxazines; Pyridines; Retrospective Studies; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir

2006
Tenofovir DF and emtricitabine vs. zidovudine and lamivudine.
    The New England journal of medicine, 2006, Jun-08, Volume: 354, Issue:23

    Topics: Adenine; Bone Density; Deoxycytidine; Drug Resistance, Viral; Emtricitabine; HIV; HIV Infections; Humans; Lamivudine; Mutation; Organophosphonates; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine

2006
Nephrotoxicity in a child with perinatal HIV on tenofovir, didanosine and lopinavir/ritonavir.
    Pediatric nephrology (Berlin, Germany), 2006, Volume: 21, Issue:7

    Topics: Adenine; Anti-HIV Agents; Child; Diabetes Insipidus, Nephrogenic; Didanosine; Drug Therapy, Combination; Fanconi Syndrome; Female; HIV; HIV Infections; HIV Protease Inhibitors; Humans; Kidney; Kidney Diseases; Lopinavir; Organophosphonates; Pregnancy; Pregnancy Complications; Pyrimidinones; Ritonavir; Tenofovir

2006
Long-term follow-up of patients with initial early virologic failure after being treated with once-daily tenofovir/abacavir/lamivudine.
    AIDS patient care and STDs, 2006, Volume: 20, Issue:9

    Topics: Adenine; Anti-HIV Agents; Dideoxynucleosides; Drug Administration Schedule; Drug Resistance, Viral; Drug Therapy, Combination; Follow-Up Studies; HIV; HIV Infections; Humans; Lamivudine; Organophosphonates; RNA, Viral; Tenofovir; Treatment Failure

2006
Acyclic nucleoside phosphonates: past, present and future. Bridging chemistry to HIV, HBV, HCV, HPV, adeno-, herpes-, and poxvirus infections: the phosphonate bridge.
    Biochemical pharmacology, 2007, Apr-01, Volume: 73, Issue:7

    Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Hepacivirus; Hepatitis B virus; HIV; Humans; Organophosphonates; Papillomaviridae; Poxviridae; Tenofovir; Virus Diseases; Viruses

2007
Synthesis, anti-HIV activity, and resistance profiles of ribose modified nucleoside phosphonates.
    Bioorganic & medicinal chemistry letters, 2007, Dec-15, Volume: 17, Issue:24

    Topics: Adenine; Anti-HIV Agents; Combinatorial Chemistry Techniques; Drug Design; HIV; Molecular Structure; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tenofovir

2007
Tenofovir-based rescue therapy for advanced liver disease in 6 patients coinfected with HIV and hepatitis B virus and receiving lamivudine.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Feb-01, Volume: 46, Issue:3

    Topics: Adenine; Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; HIV; HIV Infections; Homosexuality, Male; Humans; Lamivudine; Liver Diseases; Male; Organophosphonates; Tenofovir; Transaminases; Viral Load

2008
Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus.
    The Journal of pediatrics, 2008, Volume: 152, Issue:4

    Topics: Absorptiometry, Photon; Adenine; Adolescent; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Density; Child; Female; HIV; HIV Infections; Humans; Male; Organophosphonates; Tenofovir

2008
Test of new vaginal microbicide gel show promise for women.
    The AIDS reader, 2008, Volume: 18, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adenine; Administration, Intravaginal; Anti-Infective Agents, Local; Anti-Retroviral Agents; Female; HIV; HIV Seronegativity; Humans; India; Organophosphonates; Safety; Tenofovir; Treatment Outcome; United States; Vaginal Creams, Foams, and Jellies

2008
AIDS research. New drug shows promise in monkeys.
    Science (New York, N.Y.), 1995, Nov-17, Volume: 270, Issue:5239

    Topics: Adenine; Animals; Antiviral Agents; HIV; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir

1995
Inhibition of visna virus replication by 2',3'-dideoxynucleosides and acyclic nucleoside phosphonate analogs.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:12

    Topics: Animals; Antiviral Agents; Choroid Plexus; Dideoxynucleosides; HIV; Microbial Sensitivity Tests; Nucleosides; Organophosphonates; Reverse Transcriptase Inhibitors; Sheep; Virus Replication; Visna-maedi virus

1993
The human immunodeficiency virus(HIV) inhibitor 9-(2-phosphonylmethoxyethyl)adenine (PMEA) is a strong inducer of differentiation of several tumor cell lines.
    International journal of cancer, 1995, Mar-29, Volume: 61, Issue:1

    Topics: Adenine; Adenine Nucleotides; Animals; Antineoplastic Agents; Antiviral Agents; Cell Differentiation; Cell Division; Choriocarcinoma; HIV; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Organophosphonates; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tumor Cells, Cultured

1995
Synthesis and biological evaluation of1',2'-seconucleo-5'- phosphonates.
    Journal of medicinal chemistry, 1996, Mar-01, Volume: 39, Issue:5

    Topics: Adenine; Adenoviruses, Human; Antiviral Agents; Cystine; HIV; Molecular Structure; Nucleotides; Organophosphonates; Organophosphorus Compounds; RNA Viruses; Thymine; Uracil

1996
Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines.
    Molecular pharmacology, 1996, Volume: 50, Issue:2

    Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Deoxyadenine Nucleotides; Granulocyte-Macrophage Colony-Stimulating Factor; Herpesvirus 1, Human; HIV; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Organophosphonates; Vero Cells

1996
Anti-human immunodeficiency virus activity and cellular metabolism of a potential prodrug of the acyclic nucleoside phosphonate 9-R-(2-phosphonomethoxypropyl)adenine (PMPA), Bis(isopropyloxymethylcarbonyl)PMPA.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:3

    Topics: Adenine; Anti-HIV Agents; Blood Platelets; HIV; Humans; Leukocytes, Mononuclear; Organophosphonates; Organophosphorus Compounds; Prodrugs; T-Lymphocytes; Tenofovir

1998
Antiviral activities of 9-R-2-phosphonomethoxypropyl adenine (PMPA) and bis(isopropyloxymethylcarbonyl)PMPA against various drug-resistant human immunodeficiency virus strains.
    Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:6

    Topics: Adenine; Anti-HIV Agents; Dose-Response Relationship, Drug; Drug Resistance, Multiple; HIV; Humans; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Tenofovir; Virion

1998
Administration of 9-[2-(phosphonomethoxy)propyl]adenine (PMPA) for prevention of perinatal simian immunodeficiency virus infection in rhesus macaques.
    AIDS research and human retroviruses, 1998, Jun-10, Volume: 14, Issue:9

    Topics: Adenine; Animals; Animals, Newborn; Anti-HIV Agents; Antibodies, Viral; Cesarean Section; Chimera; Drug Administration Schedule; Female; HIV; HIV Infections; Humans; Macaca mulatta; Organophosphonates; Organophosphorus Compounds; Pregnancy; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Treatment Outcome

1998
Prolonged survival without neurological improvement in patients with AIDS-related progressive multifocal leukoencephalopathy on potent combined antiretroviral therapy.
    Journal of neurovirology, 1999, Volume: 5, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; CD4 Lymphocyte Count; Cidofovir; Cytosine; Demyelinating Diseases; Female; France; HIV; HIV Long-Term Survivors; HIV Protease Inhibitors; Humans; JC Virus; Leukoencephalopathy, Progressive Multifocal; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Prospective Studies; Retrospective Studies; Survival Rate; Time Factors; Viral Load

1999
Intralesional or topical cidofovir (HPMPC, VISTIDE) for the treatment of recurrent genital warts in HIV-1-infected patients.
    AIDS (London, England), 1999, Oct-01, Volume: 13, Issue:14

    Topics: Administration, Topical; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Condylomata Acuminata; Cytosine; DNA, Viral; HIV; Humans; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Recurrence; Tumor Virus Infections; Viral Load

1999
Early HIV infection in vivo: branching-process model for studying timing of immune responses and drug therapy.
    Mathematical biosciences, 2000, Volume: 165, Issue:2

    Topics: Adenine; Animals; Anti-HIV Agents; Computer Simulation; Disease Progression; HIV; HIV Infections; Humans; Macaca; Macrophages; Models, Immunological; Organophosphonates; Organophosphorus Compounds; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Soman; Stochastic Processes; Tenofovir; Time Factors; Viral Load

2000
Scientific basis for PEP rests in animal trials.
    AIDS alert, 1997, Volume: 12, Issue:9

    Topics: Adenine; Animals; Anti-HIV Agents; Centers for Disease Control and Prevention, U.S.; Health Personnel; HIV; HIV Infections; Humans; Macaca; Nevirapine; Occupational Diseases; Organophosphonates; Organophosphorus Compounds; Pan troglodytes; Pyridines; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Tenofovir; United States; Zidovudine

1997
Vaccines. Monkey puzzles.
    Science (New York, N.Y.), 2002, Jun-28, Volume: 296, Issue:5577

    Topics: Acquired Immunodeficiency Syndrome; Adenine; AIDS Vaccines; Animals; Anti-HIV Agents; Clinical Trials as Topic; Haplorhini; HIV; Humans; Killer Cells, Natural; Macaca mulatta; Organophosphonates; Organophosphorus Compounds; SAIDS Vaccines; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Viremia

2002
Different pattern of activity of inhibitors of the human immunodeficiency virus in lymphocytes and monocyte/macrophages.
    Antiviral research, 1992, Volume: 17, Issue:4

    Topics: Adenine; Antibodies, Viral; Antiviral Agents; Benzodiazepines; CD4 Antigens; Cytokines; Didanosine; Doxorubicin; Drug Interactions; HIV; HIV Infections; Humans; Imidazoles; Leukocytes, Mononuclear; Lymphocytes; Macrophages; Monocytes; Organ Specificity; Organophosphonates; Zalcitabine; Zidovudine

1992
Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine.
    Antiviral research, 1992, Volume: 19, Issue:3

    Topics: Adenine; Antiviral Agents; Cell Line; Cytomegalovirus; Drug Evaluation, Preclinical; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus

1992
Preparation of 35S-labeled polyphosphorothioate oligodeoxyribonucleotides by use of hydrogen phosphonate chemistry.
    Analytical biochemistry, 1990, Volume: 188, Issue:1

    Topics: Base Sequence; DNA; Electrophoresis, Polyacrylamide Gel; HIV; Indicators and Reagents; Isotope Labeling; Molecular Sequence Data; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Organophosphonates; RNA; RNA, Messenger; RNA, Viral; Sulfur; Sulfur Radioisotopes; Thionucleotides

1990
Intracellular metabolism and mechanism of anti-retrovirus action of 9-(2-phosphonylmethoxyethyl)adenine, a potent anti-human immunodeficiency virus compound.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Feb-15, Volume: 88, Issue:4

    Topics: Adenine; Animals; Antiviral Agents; Biotransformation; Cattle; Cell Line; DNA Polymerase II; HIV; Humans; Kinetics; Organophosphonates; Phosphorylation; Reverse Transcriptase Inhibitors; Ribose-Phosphate Pyrophosphokinase; Thymus Gland; Tritium

1991
9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Jun-01, Volume: 88, Issue:11

    Topics: Adenine; Animals; Antiviral Agents; Avian Myeloblastosis Virus; Cell Line; Cell Transformation, Neoplastic; DNA Replication; HIV; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Purines; Retroviridae; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Structure-Activity Relationship

1991
Investigation of DNA biosynthesis catalyzed by DNA polymerases: approach of synthesis of compounds with anti-HIV activity.
    Nucleic acids symposium series, 1991, Issue:24

    Topics: Animals; Antiviral Agents; Deoxyribonucleotides; DNA Nucleotidylexotransferase; DNA Replication; DNA-Directed DNA Polymerase; HIV; Humans; Indicators and Reagents; Organophosphonates; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Substrate Specificity

1991
Synthesis of some 3',5'-dideoxy-5'-C-phosphonomethyl nucleosides.
    Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1991, Volume: 45, Issue:7

    Topics: Antiviral Agents; Cells, Cultured; HIV; Humans; Nucleosides; Organophosphonates

1991
Backbone modified oligodeoxynucleotides: stereoselective synthesis of methylphosphonates and HIV inhibitory capacity of phosphorothioates.
    Nucleic acids symposium series, 1991, Issue:24

    Topics: Antiviral Agents; Base Sequence; HIV; Indicators and Reagents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Organophosphonates; Organothiophosphates

1991
Suppression of feline immunodeficiency virus infection in vivo by 9-(2-phosphonomethoxyethyl)adenine.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:8

    Topics: Adenine; Animals; Antiviral Agents; Cats; Cell Line; HIV; Immunologic Deficiency Syndromes; Opportunistic Infections; Organophosphonates; Retroviridae; Retroviridae Infections; T-Lymphocytes; Virus Replication; Zidovudine

1990
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8

    Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine

1990
Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7

    Topics: Adenine; Animals; Antiviral Agents; Cytopathogenic Effect, Viral; HIV; HLA-D Antigens; Humans; Hydrolysis; Mice; Mice, Inbred C3H; Organophosphonates; Organophosphorus Compounds; Purines; Pyrimidines; Sarcoma Viruses, Murine; Structure-Activity Relationship; Virus Replication

1988
Marked in vivo antiretrovirus activity of 9-(2-phosphonylmethoxyethyl)adenine, a selective anti-human immunodeficiency virus agent.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:1

    Topics: Adenine; Animals; Antiviral Agents; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; HIV; Mice; Mice, Inbred Strains; Moloney murine sarcoma virus; Organophosphonates; Sarcoma, Experimental

1989