organophosphonates has been researched along with Disease Models, Animal in 206 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.43) | 18.7374 |
| 1990's | 30 (14.56) | 18.2507 |
| 2000's | 90 (43.69) | 29.6817 |
| 2010's | 73 (35.44) | 24.3611 |
| 2020's | 8 (3.88) | 2.80 |
| Authors | Studies |
|---|---|
| Makino, K; Takeuchi, I; Tanaka, K | 1 |
| Bensman, T; Birnkrant, D; Cao, Y; Chan-Tack, K; Choi, SY; Donaldson, E; Ghantous, H; Harrington, P; McMillan, D; Myers, L; O'Rear, J; Seaton, M; Struble, K; Valappil, T | 1 |
| Tang, F; Wei, M; Wu, X; Zhang, J; Zhang, M; Zhou, Y | 1 |
| Aliakbarzadeh, F; Hashemi, R; Khodagholi, F; Motamedi, F; Naderi, N; Naderi, S; Pourbadie, HG; Sayehmiri, F | 1 |
| Georgieva, S; Peneva, P; Rangelov, M; Tchekalarova, J; Todorov, P; Todorova, N | 1 |
| Delaune, D; Iseni, F | 1 |
| Chen, W; Fu, X; Li, M; Lim, LY; Liu, G; Mo, J; Wang, K; Wang, L | 1 |
| Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; Jarrah, S; Jarvis, D; Jayatilaka, KAPW; Jemal-Turki, A; Jeon, YK; Jeong, N; Jeong, SH; Jeong, SY; Jermy, M; Jhaveri, K; Ji, H; Ji, K; Ji, RY; Jiang, F; Jiang, J; Jiang, X; Jiang, Y; Jiao, Q; Jilani, K; Jiménez-Guerrero, P; Jin, L; Jo, YH; Johnson, JG; Johnson, ML; Jones, WS; Jose, S; Jularic, M; Jung, I; Jung, YJ; Jungen, C; Junttila, MR; Kache, S; Kahanovitch, U; Kalantzi, KI; Kallio, T; Kamnoedboon, P; Kang, CH; Kang, H; Kang, J; Kang, KW; Kapoor, P; Karmakar, D; Kartalis, A; Kauranen, P; Kazocina, A; Keikha, F; Keltai, M; Kershaw, SV; Kettani, M; Khalvati, S; Khandhar, S; Khosla, N; Kiely, CJ; Kim, CC; Kim, H; Kim, MJ; Kim, Y; Kim, YH; Kim, YT; Kimoto, E; Kiyu, A; Klatt, N; Kobayashi, M; Koh, J; Köhler, R; Kondadasula, SV; Kong, H; Kong, W; Kong, X; Kotidis, A; Kotwal, A; Kouvari, M; Kozhinov, AN; Kruger, D; Kuang, S; Kuang, Y; Kubota, M; Kuklik, P; Kumar, P; Kumar, SK; Kuo, YF; Kurup, SP; Kusuhara, H; Kuswanto, H; Lacouture, ME; Lambin, P; Lang, CC; Langroudi, FH; Lanman, RB; Larsen, OH; Laskin, J; Le, VH; Leach, M; Lee, BG; Lee, DF; Lee, DS; Lee, HJ; Lee, SB; Lee, YA; Lei, Y; Lekashvili, O; Lelj, F; Lemin, AS; Lemoine, J; Leuschner, R; Li, B; Li, BT; Li, C; Li, D; Li, F; Li, G; Li, H; Li, HW; Li, J; Li, M; Li, P; Li, Q; Li, S; Li, W; Li, X; Li, XY; Li, Y; Li, Z; Lian, Y; Liang, C; Liao, J; Liao, W; Liao, Y; Lin, D; Lin, W; Lin, YL; Lindbäck, J; Lindsay, AP; Ling, J; Linser, PJ; Liu, C; Liu, H; Liu, JJ; Liu, L; Liu, Q; Liu, SF; Liu, X; Liu, Y; Liu, Z; Liu, ZM; Lo Sterzo, C; Lo, ECM; Lobchuk, MM; Lodge, TP; Logotheti, S; Lonial, S; Lopes, G; Lopes, RD; Lopez, J; Lopez, SA; López-Santos, AL; López-Sendón, JL; Loring, Z; Louis, C; Lovita, AND; Lu, DZ; Lu, H; Lu, J; Lu, K; Lu, TT; Lu, Y; Luengo, A; Lum, LG; Luna, JM; Luo, L; Luo, R; Luo, T; Luo, X; Luo, Z; Lv, B; Lymperopoulos, N; Lyras, A; Lyu, Y; M Kannan, A; Ma, H; Ma, M; Ma, Q; Ma, S; Ma, WY; Ma, Y; Maalouf, E; Machado, FA; Maeda, K; Magrans, JO; Maharani, A; Maia, G; Mainwaring, RD; Maji, TK; Majumdar, K; Mannarino, MR; Mansuri, MS; Marinescu, SC; Markatos, G; Marquardt, S; Marraiki, N; Martens, C; Martínez, TJ; Marumo, K; Maruyama, H; Marwani, HM; Marzo, I; Masrati, G; Matamba, P; Mathialagan, S; Matys, J; Mayatra, JM; Mboua, PC; McArthur, T; McCrimmon, RJ; McIntosh, S; McSpadden, S; Medina-Campos, ON; Medvedovsky, AT; Mei, Z; Mekontso-Dessap, A; Menezes, AMB; Meng, J; Meng, P; Meng, Y; Menter, A; Mets, MB; Mets-Halgrimson, R; Metzger, T; Metzler-Nolte, N; Meyer, C; Mi, Y; Michailoviene, V; Mikrogeorgiou, A; Militz, H; Miller Iii, TF; Minarowska, A; Mir, S; Miron, I; Miyake, T; Moayer, F; Modi, S; Moeller, SJ; Mohamad, MN; Mohammed, EHM; Mokhonov, VV; Mondal, A; Moore, J; Moravcova, M; Mordi, IR; Mordi, NA; Mortensen, NP; Moscariello, C; Moser, J; Moynahan, ME; Mu, J; Mu, W; Mudduwa, LKB; Mukherjee, S; Mukhtar, A; Mulkey, DK; Murr, N; Mushtaq, Z; Muthuswamy, N; Mutlu, O; Muto, C; Myroforou, I; Na, KJ; Nabi, M; Nagornov, KO; Nagy, RJ; Naik, A; Nakajima, K; Nam, KT; Nam, YW; Namburath, M; Nammour, S; Namour, A; Namour, M; Nanan, S; Natsume, H; Nave, S; Naveed, A; Nazir, H; Ndubaku, C; Nedospasov, SA; Neradilek, MB; Newcomb, C; Nguépy Keubo, FR; Nguyen, M; Ning, J; Ning, Q; Noguchi, S; Nordahl, SHG; Nordfalk, KF; Norton, L; Noupoue, EM; Nouri, SS; Nowak, JK; Núñez, K; Oakes, K; Odegaard, JI; Ogorodnikova, OL; Ogunsuyi, O; Oh, HK; Oh, HR; Oh, KH; Ohgi, K; Okunade, KS; Oliveira, AG; Olorunfemi, G; Olsen, ML; Olson, BA; Omari, KW; Ondruschka, B; Orfali, R; Orkopoulos, A; Orlowski, RZ; Oser, SM; Oser, TK; Özcan, M; Padilla, V; Paeng, JC; Pajuelo-Lozano, N; Pal, SK; Palmieri, S; Palomeque, E; Pan, W; Panagiotakos, DB; Pandey, M; Pang, D; Pang, Q; Pangarah, CA; Panny, A; Paparella, A; Papirio, S; Papouskova, K; Parang, K; Park, HJ; Park, IK; Park, S; Parker, TL; Parkhomenko, A; Parmon, VN; Parsons, B; Parsons, J; Patel, PR; Patil, S; Patsourakos, NG; Patterson, KC; Pavlidis, P; Pedernera, M; Pedersen, R; Pedraza-Chaverri, J; Pellegrini, M; Peña-Chora, G; Pereira, EDM; Pereira, MADS; Peretz, A; Perez-Padilla, R; Perlman, GY; Perona, R; Petras, C; Phuntsho, S; Picada, JN; Pinder, TA; Piper, LFJ; Pirozzi, F; Pirro, M; Pleckaityte, M; Ploutz-Snyder, LL; Ploutz-Snyder, R; Pogorzelski, A; Poles, L; Postma, AA; Prager, A; Prakash, J; Punn, R; Pützer, BM; Qi, J; Qi, MC; Qi, Y; Qian, J; Qian, Y; Qiang, L; Qiu, J; Qu, Y; Rabiu, KA; Rahighi, S; Rahman, MM; Rahmani, B; Rajkumar, SV; Ramanathan, R; Raras, TYM; Rashi, Y; Rasool, G; Rathore, MG; Ratnawati, R; Ratola, N; Raucci, U; Ray, SK; Razavi, P; Razazi, K; Razek, S; Razi, SS; Reback, M; Reddy, K; Rees, DC; Reginatto, FH; Reich, H; Reis-Filho, JS; Ren, X; Ren, Y; Renner, G; Rey, G; Reymen, B; Riaz, M; Ricci, A; Richardson, PG; Richter, C; Riga, M; Ritchie, C; Rivoal, S; Roberts, W; Robson, ME; Rocha, GZ; Rodrigues, AD; Rogach, AL; Rojas, A; Rosenberg, A; Rosenberg, E; Rosenheck, RA; Roslan, K; Rothenberger, C; Rouschop, KMA; Rubagumya, F; Ryan, CM; Ryder, JW; Saad, MJA; Sacan, O; Sacchi, A; Sahebkar, A; Saini, A; Sainz, B; Sajo, EA; Sakizadeh, J; Saleh, AA; Salgado Júnior, IB; Salvi, R; Samoylova, YV; Samuni, A; Sanchez, DM; Sanchez-Perez, I; Santos, M; Sarapulova, A; Sardot, T; Saud, N; Sauerbier, P; Scaltriti, M; Schaeffer, B; Schalk, DL; Scherschel, K; Schijven, MP; Schreuder, HWR; Schuhmacher, M; Schultz-Lebahn, A; Schwarzl, J; Scott, JM; Sebayang, SK; Seeger, ZL; Segabinazi Peserico, C; Selenica, P; Serio, A; Seruga, B; Shah, A; Shah, C; Shah, PD; Shahrokh Tehraninezhad, E; Shan, A; Shao, Z; Sharma, AMR; Sharma, RK; Shen, J; Shen, R; Shi, X; Shi, Y; Shi, ZE; Shih, YC; Shimohata, H; Shimpi, N; Shin, SH; Shon, HK; Shuvy, M; Siddique, AB; Siegbahn, A; Sikandar, M; Silvani, Y; Singh, A; Singh, AK; Singh, D; Singh, JS; Singh, KP; Singh, M; Situ, B; Skipper, MT; Skouloudi, M; Sloane, BF; Smyrnioudis, N; Snyder, MA; Söhnchen, C; Solis Condor, R; Solit, DB; Someya, S; Song, H; Song, J; Song, W; Song, Y; Sorokina, KN; Soshi, S; Soyer, P; Spitschak, A; Sreekrishnan, TR; Srinivasan, M; Staruschenko, A; Steel, A; Stefan-van Staden, RI; Stein, AM; Strayer, H; Struthers, AD; Su, H; Su, Q; Su, X; Sudore, RL; Sugimura, H; Sugiyama, Y; Sujuti, H; Sumner, SJ; Sun, B; Sun, D; Sun, H; Sun, J; Sun, JY; Sun, X; Sun, Y; Sun, Z; Sung, YC; Surenaud, M; Sutimantanapi, D; Suwandaratne, NS; Swaroop, S; Sychrova, H; Syed, A; Szczepanik, M; Szederjesi, J; Szodorai, R; Tacy, TA; Tadelle, RM; Takayasu, M; Tammeveski, K; Tan, H; Tan, M; Tang, HX; Tang, S; Tang, X; Tanokura, M; Tao, F; Tao, H; Tarafdari, A; Tarín-Carrasco, P; Tasson Tatang, C; Teixeira, JP; Thakur, A; Theobald, A; Thevenot, P; Thomaidis, K; Tian, J; Tillib, SV; Toma, C; Tomita, M; Tonchev, I; Tong, F; Toy, W; Trypuć, M; Tselepis, AD; Tsetseris, L; Tsikouri, GE; Tsikouris, EI; Tsoplifack, CB; Tsoumani, ME; Tsujimoto, R; Tsybin, YO; Tu, J; Tu, TM; Turco, M; Turkyilmaz, IB; Uddin, MJ; Ung, J; Unsihuay, D; Utsunomiya, T; Vagenende, B; Vaishnav, J; Valdes, C; Validad, MH; Valle, J; van Ginkel, MPH; van Grevenstein, WMU; Vanderpuye, V; Vasan, N; Vasilenko, EA; Vasques, GJ; Vavoulis, P; Verani, A; Veziroglu, E; Viegas, A; Vitali, MG; Vitsas, G; Voccio, JP; Vogiatzidis, C; Volow, A; Volpin, F; Vourvahis, M; Wagner, LI; Walkowiak, J; Wallace, R; Wallentin, L; Wan, D; Wan, L; Wan, T; Wang, C; Wang, F; Wang, FN; Wang, H; Wang, J; Wang, L; Wang, Q; Wang, S; Wang, T; Wang, W; Wang, X; Wang, XW; Wang, Y; Wang, YS; Wang, Z; Ward, J; Ward, L; Waseem, R; Watson, DF; Weber, P; Wehrmeister, FC; Wei, CH; Wei, H; Wei, L; Wei, Q; Wei, Y; Weinstock, RS; Weiss, M; Welborn, M; Wen, L; Wen, LM; Wen, Q; Wen, Z; Wesseling, P; Westerbergh, J; White, K; Wick, MP; Willems, S; Wiyasa, IWA; Wójciak, R; Wolkenhauer, O; Won, HH; Wong, J; Woo, YC; Wood, LS; Wu, CT; Wu, CY; Wu, D; Wu, G; Wu, J; Wu, K; Wu, M; Wu, Q; Wu, T; Wu, W; Wu, X; Wu, XT; Wu, Y; Xi, D; Xi, J; Xiang, W; Xiang, Y; Xiao, M; Xiao, Z; Xie, H; Xie, Q; Xie, S; Xie, X; Xing, M; Xing, YL; Xu, C; Xu, X; Xu, Y; Xu, Z; Xue, F; Xue, XD; Yaglioglu, HG; Yamada, H; Yamashita, M; Yan, W; Yan, Z; Yanardag, R; Yang, D; Yang, H; Yang, K; Yang, QQ; Yang, R; Yang, S; Yang, T; Yang, X; Yang, Y; Yao, H; Yao, Y; Yari, D; Yassin, MT; Ye, C; Ye, J; Ye, Q; Yildiz, EA; Ying, S; Yoon, H; Yu, D; Yu, K; Yu, N; Yu, PL; Yuan, C; Yuan, D; Yuan, LJ; Yuan, Z; Yuen, N; Zagatto, AM; Zakaria, Y; Zalewski, AM; Zamora, S; Zavorotinskaya, T; Zeid, JL; Zeinoun, T; Zeng, C; Zerby, HN; Zhan, X; Zhang, A; Zhang, D; Zhang, E; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, M; Zhang, P; Zhang, Q; Zhang, QY; Zhang, RG; Zhang, S; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, CK; Zhao, H; Zhao, J; Zhao, K; Zhao, Q; Zhao, S; Zhao, T; Zhao, XQ; Zhao, Y; Zhao, Z; Zheng, J; Zheng, L; Zheng, Y; Zhou, B; Zhou, G; Zhou, L; Zhou, T; Zhou, X; Zhu, C; Zhu, J; Zhu, Y; Zhu, ZQ; Zhuang, T; Zimmermannova, O; Zin, NNINM; Zisimos, K; Zoghebi, KA; Zonder, JA; Zou, C; Zwirner, J | 1 |
| Beigelman, LN; Blatt, LM; Chanda, S; Deval, J; Gupta, K; Jekle, A; Lin, TI; Luong, XG; McGowan, D; Misner, D; Mukherjee, S; Raboisson, P; Stevens, SK; Stoycheva, A; Symons, JA; Vandyck, K; Williams, C | 1 |
| Brundage, T; Dunn, JA; Foster, SA; Gainey, MR; Grossi, IM; Khouri, JM; Krile, RT | 1 |
| Spencer, JF; Tollefson, AE; Toth, K; Wold, WSM; Ying, B | 2 |
| Achdout, H; Erez, N; Israeli, O; Israely, T; Lustig, S; Melamed, S; Paran, N; Politi, B; Tamir, H; Waner, T | 1 |
| Cho, I; Cho, JH; Song, HO | 1 |
| Donahue, RR; Doolen, S; Grachen, CM; Iannitti, T; Shaw, BC; Taylor, BK | 1 |
| Andrei, G; Brisse, E; Imbrechts, M; Matthys, P; Mitera, T; Snoeck, R; Vandenhaute, J; Wouters, CH | 1 |
| Fu, J; Gao, F; Gao, Y; Li, Y; Meng, F; Yang, C | 1 |
| Fan, J; Harteg, C; Hartline, CB; Kashemirov, BA; Lipka, E; Lyu, J; McKenna, CE; Prichard, MN; Reyna, D; Richard, ET; Spencer, JF; Tollefson, AE; Toth, K; Wold, WSM; Ying, B | 1 |
| Makino, K; Shimamura, Y; Takeuchi, I; Terada, H | 1 |
| Basile, I; Caillaud, C; Charbonné, HV; Da Silva, A; Daurat, M; El Cheikh, K; Garcia, M; Gary-Bobo, M; Godefroy, A; Maynadier, M; Morère, A; Sacconi, S; Schoser, B | 1 |
| Koeberl, DD; Lian, B; Liao, XH; Lim, A; Masamune, H; Refetoff, S; Tran, B; Waskowicz, LR; Yen, PM; Zhou, J | 1 |
| Abdi, M; Alizadeh, H; Tripathi, T | 1 |
| Choo, DI; Nassar, M; Reece, AL; Sidell, DR; Ward, JA | 1 |
| Herold, BC; Jandl, T; Kiser, PF; Nagaraja, U; Nixon, B; Taneva, E; Teller, RS; Wang, Y | 1 |
| Andrei, G; De Schutter, T; Duraffour, S; Matthys, P; Mitera, T; Snoeck, R; Topalis, D; van den Oord, J | 1 |
| Damon, IK; Foster, S; Gates, I; Lanier, ER; Li, Y; Olson, VA; Smith, SK; Trost, LC | 1 |
| Chung, CL; Kassell, NF; Kwan, AL; Lee, PY; Loh, JK; Tsai, HP; Wang, CJ; Wu, BN; Wu, SC | 1 |
| Akkina, R; Kashuba, ADM; LeCureux, J; Remling-Mulder, L; Sykes, C; Veselinovic, M; Yang, KH | 1 |
| Alt, C; Shankar, GN | 1 |
| Dagley, A; Downs, B; Hagloch, J; Smee, DF; Tarbet, EB | 1 |
| Black, DH; Brush, LA; Eberle, R; Maxwell, LK; Mccormack, KA; Payton, ME; Ritchey, JW; Wright, G | 1 |
| Buller, RM; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B | 1 |
| Chen, J; Gross, S; Pollock, C; Saad, S; Wong, M; Wong, MG; Zhang, J | 1 |
| Breuer, E; Frant, J; Hoffman, A; Maresca, A; Reich, R; Shai, O; Supuran, CT; Suresh, RR | 1 |
| Foster, SA; Godin, SJ; Keilholz, L; Khouri, J; Long, J; Rose, ML; Trost, LC | 1 |
| Chen, J; Kim, DH; Larson, AC; Omary, RA | 1 |
| Chandra, N; Doncel, GF; Fichorova, RN; Mendonca, K; Murray, R; Yamamoto, HS | 1 |
| Destache, CJ; Fan, W; Kang, G; Li, Q; Li, Y; Lu, W; Tso, FY; Wood, C; Yuan, Z | 1 |
| Blondiaux, J; Haque, A; Hober, D | 1 |
| Alonso, EN; Curino, AC; Facchinetti, MM; Fall, Y; Fermento, ME; Ferronato, MJ; Gandini, NA; Mascaró, E; Obiol, DJ; Raimondi, AR; Salomón, DG; Vitale, C | 1 |
| Judd, BE; Ledbetter, EC; Mohammed, HO; Pennington, MR; Spertus, CB; Van de Walle, GR | 1 |
| Liu, S; Parajuli, KR; You, Z; Zhang, Q | 1 |
| Arisawa, T; George, J; Hayashi, N; Hiratake, J; Tamura, K; Toshikuni, N; Tsuchishima, M; Tsutsumi, M | 1 |
| Ahmed, MM; Connor, MP; Howard, NS; Lospinoso, J; Maturo, SC; O'Connor, P; Palazzolo, M; Thompson, ME | 1 |
| Buller, RM; Crump, R; Korom, M; Parker, S | 1 |
| Brundage, T; Chittick, G; Morrison, M; Nichols, WG | 1 |
| Abel, K; Bischofberger, N; Brignolo, LL; Cihlar, T; Durand-Gasselin, L; Jerome, C; Kearney, BP; Marthas, ML; Moore, J; Ray, AS; Reiser, H; Spinner, A; Van Rompay, KK | 1 |
| Butler, SD; Cote, PJ; George, AL; Gerin, JL; Menne, S; Tennant, BC; Tochkov, IA; Xiong, S; Zhu, Y | 1 |
| Bellacicco, AL; Buonavoglia, C; Camero, M; Crescenzo, G; Decaro, N; Martella, V; Neyts, J; Tarsitano, E; Tempesta, M | 1 |
| Arhin, FF; Caron, L; Delorme, D; Dietrich, E; Fadhil, I; Ferreira, SS; Houghton, TJ; Kang, T; Laquerre, K; Lehoux, D; Liu, J; Moeck, G; Ostiguy, V; Parr, TR; Poirier, H; Rafai Far, A; Sarmiento, I; Tanaka, KS; Viens, F | 1 |
| Boyer, SH; Cable, EE; Erion, MD; Fujitaki, JM; Godwin, JL; Hecker, SJ; Hou, J; Jacintho, JD; Jiang, H; Li, H; Li, W; Reddy, MV; Schulz, WG; Wu, R | 1 |
| Buller, RM; Huso, DL; Sagartz, JE; Schultz, DA | 1 |
| Smee, DF | 1 |
| Buller, RM; Lanier, R; Oberle, C; Painter, G; Parker, S; Robertson, A; Schriewer, J | 1 |
| Buller, RM; Hembrador, E; Lanier, R; Oberle, C; Painter, G; Parker, S; Robertson, A; Siddiqui, AM | 1 |
| Inoue, H; Ishikawa, M; Kadonosono, K; Sonoda, KH; Uchio, E | 1 |
| Brenchley, J; Buckler-White, A; Igarashi, T; Kubo, M; Lafont, B; Lee, W; Martin, MA; Nishimura, Y; Shingai, M | 1 |
| Foster, C; Gibb, DM; Lyall, H; Olmscheid, B; Pearce, G; Zhang, S | 1 |
| Gordon, YJ; Romanowski, EG; Yates, KA | 2 |
| Cox, RA; Deyo, DJ; Hawkins, HK; Herndon, DN; Jacob, S; Traber, DL | 1 |
| Abraham, WM; Andrade-Gordon, P; de Garavilla, L; Greco, MN; Haertlein, BJ; Maryanoff, BE; Wells, GI | 1 |
| Cheshenko, N; Fakioglu, E; Herold, BC; Keller, MJ; Mesquita, PM; Wilson, SS | 1 |
| Dang, Q; Dare, J; Erion, MD; Gibson, T; Kasibhatla, SR; Liu, Y; Potter, SC; Reddy, KR; Scarlato, GR; Taplin, F; van Poelje, PD; Xiao, W | 1 |
| Buller, RM; Parker, S; Sagartz, JE; Schriewer, J; Stabenow, J; West, C | 1 |
| Bhattacharjee, PS; Capriotti, JA; Clement, C; Foster, TP; Hill, JM; Hobden, JA; Kumar, M; Liang, B; Mahmud, R; Thompson, HW | 1 |
| Armenise, C; Bellacicco, AL; Buonavoglia, C; Camero, M; Crescenzo, G; Marinaro, M; Tarsitano, E; Tempesta, M | 1 |
| Fujino, T; Kageyama, A; Nozawa, Y; Yamada, S; Yoshida, A | 1 |
| Collins, DJ; Kern, ER; Lampert, B; Painter, GR; Quenelle, DC; Rice, TL | 1 |
| Beadle, JR; Bernstein, DI; Bravo, FJ; Cardin, RD; Hostetler, KY | 1 |
| Chen, Z; Doyle, T; Finley, A; Salvemini, D | 1 |
| Aung, W; Cong, ME; Dobard, C; Garcia-Lerma, JG; Heneine, W; Mitchell, J; Sharma, S; Youngpairoj, AS | 1 |
| Adams, MM; Foster, S; Lampert, B; Moyer, RW; Painter, G; Rice, AD; Robertson, A | 1 |
| Adams, MM; Burrage, AM; Foster, S; Gray, SA; Lampert, B; Lanier, R; Lindsey, SF; Manning, BR; Moyer, RW; Painter, G; Rice, AD; Robertson, A; Smith, AJ; Swetnam, D; Wallace, G | 1 |
| Baker, DL; Bolen, AL; Emmons-Thompson, K; Fells, J; Fujiwara, Y; Gupte, R; Lee, SC; Liu, J; Miller, DD; Mills, GB; Panupinthu, N; Parrill, AL; Patil, R; Pham, TC; Siddam, A; Tigyi, G; Wang, Y; Yates, CR | 1 |
| Appella, DH; Chen, Z; Huang, S; Liu, Y; Lou, G; Norton, JT; Wang, C; Witschi, MA; Xu, Q | 1 |
| Appella, E; Denton, PW; Estes, JD; Fleming, E; Gallay, P; Garcia, JV; Kay, MS; Krisko, JF; Kwak, YT; Lu, M; Martinez-Torres, F; Othieno, F; Payne, DA; Powell, DA; Wahl, A; Welch, BD; Zein, S; Zou, W | 1 |
| Borysko, K; Breitenbach, J; Drach, JC; Hilfinger, J; Kashemirov, BA; Kijek, P; Kim, JS; McKenna, CE; Mitchell, S; Peterson, LW | 1 |
| Hayden, EC | 1 |
| Hiratake, J; Matsumura, Y; Ohkita, M; Tanaka, R; Watanabe, B; Yamamoto, S | 1 |
| Aldern, KA; Beadle, JR; Cheng, L; Chhablani, J; Conner, L; Freeman, WR; Hartmann, K; Hostetler, KY; Pearson, L; Wang, H | 1 |
| Baum, MM; Butkyavichene, I; Clark, MR; Friend, DR; Gilman, J; Kennedy, S; Kopin, E; Malone, AM; Moss, JA; Motamedi, M; Nguyen, C; Smith, TJ; Vincent, KL | 1 |
| Didier, PJ; Doyle, LA; Killeen, SZ; Marx, PA; Reddy, JD; Roy, CJ; Sivasubramani, SK; Talton, JD; Verreault, D | 1 |
| Chen, NG; Foster, S; Hartzler, H; Hembrador, E; Hruby, D; Jordan, R; Lanier, R; Mark Buller, R; Painter, G; Painter, W; Parker, S; Sagartz, JE; Schriewer, J | 1 |
| Heneine, W; Kashuba, A | 1 |
| Erez, N; Israely, T; Lustig, S; Melamed, S; Paran, N; Politi, B; Shafferman, A | 1 |
| Abel, K; Canfield, DR; Forthal, DN; Geng, Y; Heneine, W; Jayashankar, K; Johnson, JA; LaBranche, CC; Landucci, G; Lipscomb, J; Montefiori, D; Tarara, RP; Trott, KA; Van Rompay, KK | 1 |
| Murakami, T; Nakasone, T; Yamamoto, N | 1 |
| Melchjorsen, J; Paludan, SR; Reinert, LS; Søgaard, OS; Tolstrup, M; Vibholm, L; Østergaard, L | 1 |
| Grulich, AE; Poynten, IM; Zablotska, I | 1 |
| Abdou, WM; Barghash, RF; Bekheit, MS | 1 |
| Gao, Y; Li, F; Sun, R; Tian, Z; Wei, H; Xu, L; Yin, W | 1 |
| Chateau, M; Garcia, JV; Swanson, MD | 1 |
| Budeus, B; Cao, L; Chen, X; Hoffmann, D; Lu, M; Qin, B; Rayner, S; Wang, Y; Wu, C; Zhang, X | 1 |
| Chakraborty, S; Cronin, C; Jacobson, KA; Kumar, TS; Liang, BT; Mishra, S; Shen, JB; Yang, T | 1 |
| Cappellacci, L; Casabianca, A; Celeste, AG; Cerasi, A; Chiarantini, L; Dominici, S; Franchetti, P; Grifantini, M; Magnani, M; Rossi, L; Serafini, S | 1 |
| Liekens, S | 1 |
| Bischofberger, N; Lawson, JR; Marthas, ML; Schmidt, KA; Singh, R; Van Rompay, KK | 1 |
| Sidwell, RW; Smee, DF | 1 |
| Zheng, S; Zuo, Z | 1 |
| Bock, CT; Dienes, HP; Klein, C; Kubicka, S; Locarnini, S; Manns, MP; Trautwein, C; Wedemeyer, H; Wüstefeld, T | 1 |
| Bolger, GT; Bousquet, C; Cordingley, MG; Garneau, M; Kibler, P; Tremblay, F | 1 |
| Collins, DJ; Kern, ER; Quenelle, DC | 2 |
| Abe, M; Aoki, K; Iida, T; Kaneko, H; Mori, S; Ohno, S; Shigeta, S; Suzuki, O; Suzutani, T | 1 |
| Beadle, JR; Buller, RM; Hostetler, KY; Melman, L; Owens, G; Schriewer, J | 1 |
| De Clercq, E; Leyssen, P; Neyts, J; Verbeken, E | 1 |
| Bidanset, DJ; Hartline, CB; Kern, ER; Rybak, RJ | 2 |
| Beadle, JR; Bidanset, DJ; Hostetler, KY; Kern, ER; Wan, WB | 1 |
| Cote, PJ; Delaney, WE; Gerin, JL; Jacob, JR; Korba, BE; Tennant, BC; Toshkov, I | 1 |
| Bailey, KW; Sidwell, RW; Smee, DF; Wandersee, MK; Wong, MH | 1 |
| Chen, ZW; Du, GZ; Huang, D; Letvin, NL; Miller, MD; Qiu, L; Sehgal, P; Shen, L; Shen, Y | 1 |
| De Clercq, E | 2 |
| Blum, HE; Burda, MR; Dandri, M; Gocht, A; Köck, J; Matschl, U; Petersen, J; Pollok, JM; Rogiers, X; von Weizsäcker, F; Wursthorn, K; Zuckerman, DM | 1 |
| Ayach, B; Battistini, B; Blouin, A; Cernacek, P; Jeng, AY; Opgenorth, T; Tsang, J; Verreault, M; Wessale, J | 1 |
| Battistini, B; Blouin, A; Daull, P; Jeng, AY; Nantel, F; Sirois, P | 1 |
| Chang, CY; Chen, SC; Jeng, AY; Kassell, NF; Kwan, AL; Lin, TK; Lue, SI; Wu, SC; Yen, CP | 1 |
| Chang, CZ; Howng, SL; Jeng, AY; Kassell, NF; Kwan, AL; Lin, TK; Winadi, D; Wu, SC; Yen, CP | 1 |
| Breuer, E; Hadar, R; Katz, Y; Reich, R | 1 |
| Bailey, KW; Holy, A; Hostetler, KY; Sidwell, RW; Smee, DF; Wandersee, MK | 1 |
| Bullock, B; Carruth, LM; Clements, JE; Gama, L; Li, M; Mankowski, JL; Zink, MC | 1 |
| Anderson, JL; McGregor, A; Schleiss, MR | 1 |
| Gordon, YJ; Irschick, EU; Nagl, M; Romanowski, EG; Teuchner, B; Yates, KA | 1 |
| Lenaerts, L; Naesens, L | 1 |
| Allen, SD; Knorr, CW; Smee, DF; Torres, AR | 1 |
| Choo, DI; Schleiss, MR; Stroup, G; White, DR | 1 |
| Cahalan, MD; Cheng, WC; Don, A; Gonzalez-Cabrera, PJ; Jo, E; Marsolais, D; Matheu, MP; Parker, I; Rosen, H; Sanna, MG; Wang, SK; Wei, SH; Wong, CH | 1 |
| Grant, RM; Wainberg, MA | 1 |
| Adams, DR; Bashirian, S; Butera, S; Folks, TM; Greenberg, AE; Hudgens, MG; Jackson, E; Janssen, R; Johnson, J; Kim, C; Monsour, M; Otten, RA; Paxton, L; Ramos, A; Rendon, A; Soriano, V; Subbarao, S | 1 |
| Evans, DH; Hostetler, KY; Kornbluth, RS; Sidwell, RW; Smee, DF; Snarsky, V | 1 |
| Delwart, E; Heneine, W; Johnson, JA; Rompay, KK | 1 |
| Bellacicco, AL; Buonavoglia, C; Camero, M; Crescenzo, G; Neyts, J; Tempesta, M; Thiry, E; Thiry, J | 1 |
| Dumont, AS; Huang, CS; Jeng, AY; Kassell, NF; Kuo, CL; Kwan, AL; Lin, CL; Liu, CS; Su, YF; Wang, CJ; Wu, SC | 1 |
| Bischofberger, N; Blackwood, EJ; Heneine, W; Johnson, JA; Lipscomb, J; Marthas, ML; Matthews, TB; North, TW; Pedersen, NC; Singh, RP; Van Rompay, KK | 1 |
| Garrison, A; Goff, A; Lawler, J; Mucker, E; Paragas, J; Twenhafel, N | 1 |
| Bernstein, DI; Bravo, FJ; Cardin, RD | 1 |
| Coats, P; Kennedy, S; Pyne, S; Wadsworth, RM; Wainwright, CL | 1 |
| Dandekar, S; Sankaran, S; Verhoeven, D | 1 |
| Adams, D; Butera, S; Folks, T; Kim, C; Monsour, M; Otten, RA; Ramos, A; Subbarao, S | 1 |
| Adams, MM; Moyer, RW; Rice, AD | 1 |
| Andrei, G; De Clercq, E; Fiten, P; Froeyen, M; Opdenakker, G; Snoeck, R | 1 |
| Gambotto, A; Gordon, YJ; Nwanegbo, EC; Romanowski, EG | 1 |
| Clayton, MM; Feitelson, MA; Schinazi, RF; Sun, B | 1 |
| Shacklett, BL | 1 |
| Denton, PW; Estes, JD; Garcia, JV; Haase, AT; Othieno, FA; Payne, D; Powell, DA; Sun, Z; Wege, AK; Wei, BL | 1 |
| De Clercq, E; Geboes, L; Kelchtermans, H; Lenaerts, L; Matthys, P; Naesens, L; Verbeken, E | 1 |
| da Fonseca Pacheco, CM; da Fonseca Pacheco, D; de Castro Perez, A; de Francischi, JN; Duarte, ID; Klein, A | 1 |
| Bayly, CI; Belley, M; Chan, CC; Colucci, J; Dufresne, C; Giroux, A; Han, Y; Kennedy, BP; Lau, CK; Leblanc, Y; McKay, D; Scapin, G; Skorey, K; Therien, M; Wilson, MC | 1 |
| Buller, RM; Dhar, D; Painter, GR; Sagartz, JE; Spencer, JF; Toth, K; Wold, WS | 1 |
| Balzarini, J; De Clercq, E; Georgsson, G; Naesens, L; Pálsson, PA; Thormar, H; Torsteinsdóttir, S | 1 |
| Assil, KK; Bergeron-Lynn, G; Besen, G; De Clercq, E; Flores-Aguilar, M; Gangan, P; Kupperman, BD; Munguia, D; Pursley, M; Vuong, C | 1 |
| Araullo-Cruz, T; Gordon, YJ; Romanowski, EG | 1 |
| Elleder, D; Elleder, M; Kren, V; Otová, B; Panczak, A; Sladká, M | 1 |
| Elleder, D; Elleder, M; Holý, A; Kren, V; Otová, B; Panczak, A | 1 |
| De Clercq, E; Neyts, J | 1 |
| Bruggeman, CA; de Clercq, E; Havenith, M; Stals, FS; Zeytinoglu, A | 1 |
| Bravo, FJ; Kern, ER; Kier, AB; Stanberry, LR; Vogt, PE | 1 |
| Assil, KK; Bergeron-Lynn, G; Besen, G; Connor, JD; De Clercq, E; Freeman, WR; Kuppermann, BD; Munguia, D; Pursley, M; Vuong, C; Wiley, CA | 1 |
| Brun, R; DeClercq, E; Grether, Y; Holý, A; Kaminsky, R; Naesens, L; Schmid, C | 1 |
| de Oliveira, CB; LaBree, L; McDonnell, PJ; Stevenson, D; Trousdale, MD | 1 |
| Arthur, A; Caner, HH; Jeng, AY; Kassell, NF; Kwan, AL; Lappe, RW; Lee, KS | 1 |
| de Clercq, E; De Hauwere, B; Lutz, A; Maudgal, PC; Neyts, J | 1 |
| Bruggeman, CA; Kloover, JS; Stals, FS; Vanagt, WY | 1 |
| Banker, AS; Bergeron-Lynn, G; De Clercq, E; Flores-Aguilar, M; Freeman, WR; Keefe, K; Munguia, D; Rao, NA; Taskintuna, I; Wiley, CA | 1 |
| Bavbek, M; Jeng, AY; Kassell, NF; Kwan, AL; Lappe, RW; Lee, KS; Maniara, W; Toyoda, T | 1 |
| Abou-Gharbia, M; Bramlett, DR; Garrison, DT; Kinney, WA; Kowal, DM; Miller, TL; Moyer, JA; Schmid, J; Tasse, RP; Zaleska, MM | 1 |
| Kaufman, HE; Thompson, HW; Varnell, ED | 1 |
| Black, RJ | 1 |
| Acklin, P; Auberson, YP; Bischoff, S; Moretti, R; Ofner, S; Schmutz, M; Veenstra, SJ | 1 |
| Carr, MJ; Goldie, RG; Henry, PJ; Jeng, AY | 1 |
| Albrecht, M; Brandt, KD; Burr, DB; Myers, SL; O'Connor, BL | 1 |
| Groom, A; Smith, T; Turski, L; Zhu, B | 1 |
| Bolger, G; Bousquet, C; Cordingley, M; Garneau, M; Kibler, P; Lapeyre, N; Rhéaume, M | 1 |
| Battistini, B; Cloutier, R; Fournier, L; Jean, S; Jeng, AY; Kavanagh, M; Kluth, D; Major, D | 1 |
| Cordingley, MG; De Marte, J; Duan, J; Fleet, TL; Paris, W; Roopchand, D | 1 |
| Adany, I; Bischofberger, N; Buch, S; Foresman, L; Li, Z; Lifson, JD; Lopez, GJ; Narayan, O; Page, A; Smith, MS; Tsay, J; Wang, C; Wodarz, D | 1 |
| Beck, TW; Bischofberger, N; Emau, P; Follis, KE; Morton, WR; Sun, JC; Tran, CA; Tsai, CC | 1 |
| Budgeon, LR; Christensen, ND; Kreider, JW; Pickel, MD | 1 |
| Bischofberger, N; Buch, S; Foresman, L; Kumar, A; Lifson, JD; Narayan, O | 1 |
| Bischofberger, N; Dittmer, U; Heeney, J; Hunsmann, G; Lorenzen, D; Ràcz, P; Spring, M; Stahl-Hennig, C; Stolte, N; Tenner-Ràcz, K | 1 |
| Altincicek, B; Beck, E; Dreiseidler, E; Jomaa, H; Reichenberg, A; Sanderbrand, S; Schlitzer, M; Weidemeyer, C; Wiesner, J | 1 |
| Lawson, CM; Lenzo, JC; Shellam, GR | 1 |
| Bailey, KW; Sidwell, RW; Smee, DF | 2 |
| Bailly, T; Burgada, R; Chazel, V; Henge-Napoli, MH; Houpert, P; Paquet, F | 1 |
| Brown, C; Cullen, JM; Cundy, KC; Eisenberg, EJ; Gibbs, C; Li, DH; Toole, J; Wolfe, J | 1 |
| McPhaden, AR; Pyne, NJ; Pyne, S; Wadsworth, RM; Wainwright, CL; Work, LM | 1 |
| Cohen, J | 1 |
| Delmas, J; Gibbs, C; Hantz, O; Jamard, C; Schorr, O; Trépo, C; Zoulim, F | 1 |
| Julander, JG; Morrey, JD; Sidwell, RW | 1 |
| Boyd, MR; Harris, SR | 1 |
| Balzarini, J; De Clercq, E; Naesens, L; Neyts, J | 1 |
| Holy, A; Leonhardt, JA; Mead, JR; Morris, JL; Sidwell, RW; Smee, DF | 1 |
| Araullo-Cruz, T; De Clercq, E; Gordon, YJ; Romanowski, E | 1 |
| Kern, ER | 1 |
| De Clercq, E; Maudgal, PC | 2 |
| Belakhov, VV; Grinberg, GE; Ionin, BI; Levina, AA; Rachkovskaia, LA; Shatik, LI; Shenin, IuD; Shtil'bans, EB; Zaĭtseva, MB | 1 |
| Flora, L; Francis, MD; King, WR | 1 |
| Hähnel, H; Lindenhayn, K; Mühlbach, R; Schaetz, P; Schmidt, UJ | 1 |
| Bugryshev, PF; Ivannikov, AT; Kuznetsov, AA | 1 |
| Lämmler, G; Srivastava, VK; Zahner, H | 1 |
17 review(s) available for organophosphonates and Disease Models, Animal
| Article | Year |
|---|---|
Benefit-risk assessment for brincidofovir for the treatment of smallpox: U.S. Food and Drug Administration's Evaluation.
Topics: Animals; Antiviral Agents; Cytosine; Disease Eradication; Disease Models, Animal; Drug Approval; Humans; Organophosphonates; Risk Assessment; Smallpox; Treatment Outcome; United States; United States Food and Drug Administration | 2021 |
Drug Development against Smallpox: Present and Future.
Topics: Animals; Antiviral Agents; Benzamides; Biological Warfare Agents; Biomedical Research; Cytosine; Disease Models, Animal; Drug Discovery; Isoindoles; Organophosphonates; Smallpox; Variola virus | 2020 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Addressing Therapeutic Options for Ebola Virus Infection in Current and Future Outbreaks.
Topics: Amides; Amidines; Androstenes; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antiviral Agents; Benzofurans; Cytosine; Disease Models, Animal; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Immune Sera; Organophosphonates; Pyrazines; RNA, Small Interfering; Stilbenes; Virus Replication | 2015 |
Progress in the discovery of compounds inhibiting orthopoxviruses in animal models.
Topics: Adenine; Animals; Antiviral Agents; Benzamides; Cidofovir; Cytosine; Disease Models, Animal; Drug Discovery; Humans; Isoindoles; Organophosphonates; Orthopoxvirus; Prodrugs | 2008 |
Tenofovir disoproxil fumarate in pregnancy and prevention of mother-to-child transmission of HIV-1: is it time to move on from zidovudine?
Topics: Adenine; Adult; Africa South of the Sahara; Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Bone Diseases; Child; Child, Preschool; Congenital Abnormalities; Disease Models, Animal; Drug Resistance, Viral; Female; Health Services Accessibility; HIV Infections; HIV-1; Humans; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Macaca; Mitochondria; Nevirapine; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Tenofovir; Zidovudine | 2009 |
Efficacy of CMX001 as a prophylactic and presymptomatic antiviral agent in New Zealand white rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.
Topics: Animals; Antiviral Agents; Bioterrorism; Cytosine; Disease Models, Animal; Disease Transmission, Infectious; Humans; Mpox (monkeypox); Organophosphonates; Rabbits; Smallpox; Smallpox Vaccine; Vaccinia virus | 2011 |
Efficacy of CMX001 as a post exposure antiviral in New Zealand White rabbits infected with rabbitpox virus, a model for orthopoxvirus infections of humans.
Topics: Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Disease Transmission, Infectious; Dose-Response Relationship, Drug; Humans; Mpox (monkeypox); Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia virus | 2011 |
HIV prevention by oral preexposure prophylaxis.
Topics: Adenine; Administration, Oral; Animals; Anti-Retroviral Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; HIV Infections; HIV Seronegativity; Humans; Male; Mucous Membrane; Organophosphonates; Protein Binding; Rectum; Tenofovir; Vagina; Virus Replication | 2012 |
Considerations regarding antiretroviral chemoprophylaxis in MSM.
Topics: Adenine; Administration, Oral; Animals; Anti-HIV Agents; Chemoprevention; Clinical Trials as Topic; Deoxycytidine; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Emtricitabine; HIV Infections; Homosexuality, Male; Humans; Leukocytes, Mononuclear; Male; Medication Adherence; Organophosphonates; Plasma; Tenofovir; Treatment Outcome | 2012 |
The role of growth factors, angiogenic enzymes and apoptosis in neovascularization and tumor growth-collected publications.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cidofovir; Cyclohexanes; Cytosine; Disease Models, Animal; Fibroblast Growth Factor 2; Growth Substances; Hemangioma; Humans; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Organophosphonates; Organophosphorus Compounds; Rats; Sesquiterpenes; Thymidine Phosphorylase; Tumor Virus Infections | 2002 |
A review of compounds exhibiting anti-orthopoxvirus activity in animal models.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Disease Models, Animal; Humans; Mice; Mice, SCID; Nucleosides; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Poxviridae Infections; Rabbits; Smallpox; Thiosemicarbazones | 2003 |
Potential of acyclic nucleoside phosphonates in the treatment of DNA virus and retrovirus infections.
Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA Virus Infections; Drug Resistance, Viral; Humans; Organophosphonates; Organophosphorus Compounds; Retroviridae Infections; Tenofovir | 2003 |
Antiviral therapy for adenovirus infections.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Immunocompromised Host; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Organophosphonates; Ribavirin | 2006 |
Animal studies of prophylaxis.
Topics: Adenine; Animals; Anti-HIV Agents; Disease Models, Animal; Drug Administration Schedule; Interferon-alpha; Lentivirus Infections; Organophosphonates; Organophosphorus Compounds; Retroviridae Infections; Reverse Transcriptase Inhibitors; Tenofovir; Zidovudine | 1997 |
Cidofovir in the treatment of poxvirus infections.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Humans; Immunocompromised Host; Injections, Intraperitoneal; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds; Poxviridae; Poxviridae Infections | 2002 |
Value of animal models to evaluate agents with potential activity against human cytomegalovirus.
Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1991 |
2 trial(s) available for organophosphonates and Disease Models, Animal
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Short-term clinical safety profile of brincidofovir: A favorable benefit-risk proposition in the treatment of smallpox.
Topics: Adenoviridae; Adolescent; Adult; Animals; Antiviral Agents; Cytomegalovirus; Cytosine; Disease Models, Animal; Double-Blind Method; Drug Administration Schedule; Humans; Middle Aged; Organophosphonates; Orthopoxvirus; Safety; Smallpox; Young Adult | 2017 |
188 other study(ies) available for organophosphonates and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic Effects of GGsTop
Topics: Aminobutyrates; Animals; Antimetabolites, Antineoplastic; Body Weight; Collagen; Disease Models, Animal; Drug Dosage Calculations; Fluorouracil; Gels; Glutathione; Leukocytes; Male; Mice; Organophosphonates; Stomatitis | 2021 |
Adefovir accumulation in the renal interstitium triggers mast cell degranulation and promotes renal interstitial fibrosis.
Topics: Adenine; Animals; Cell Degranulation; Disease Models, Animal; Fibrosis; Humans; Kidney Diseases; Kidney Tubules; Male; Mast Cells; Organophosphonates; Rats | 2022 |
Phosphonate analog of 2-oxoglutarate regulates glutamate-glutamine homeostasis and counteracts amyloid beta induced learning and memory deficits in rats.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Glutamates; Glutamine; Hippocampus; Homeostasis; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Male; Maze Learning; Memory Disorders; Organophosphonates; Peptide Fragments; Rats; Rats, Wistar | 2022 |
Synthesis, characterization and anticonvulsant activity of new series of N-modified analogues of VV-hemorphin-5 with aminophosphonate moiety.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Hemoglobins; Male; Mice; Mice, Inbred ICR; Molecular Docking Simulation; Organophosphonates; Peptide Fragments; Receptors, Opioid, kappa; Seizures; Solid-Phase Synthesis Techniques; Structure-Activity Relationship | 2019 |
Metal ion-responsive nanocarrier derived from phosphonated calix[4]arenes for delivering dauricine specifically to sites of brain injury in a mouse model of intracerebral hemorrhage.
Topics: Animals; Benzylisoquinolines; Blood-Brain Barrier; Calixarenes; Cerebral Hemorrhage; Disease Models, Animal; Drug Carriers; Humans; Interleukin-1beta; Ions; Male; Matrix Metalloproteinase 9; Metals; Mice; Mice, Inbred C57BL; Nanostructures; Neurons; Neuroprotective Agents; Organophosphonates; Phenols; Reactive Oxygen Species; Tetrahydroisoquinolines | 2020 |
Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH).
Topics: Acetates; Angiopoietin-Like Protein 4; Animals; Cell Line, Tumor; Cholesterol, LDL; Diet, High-Fat; Disease Models, Animal; Drug Evaluation, Preclinical; Hepatocytes; Humans; Iodide Peroxidase; Liver; Malate Dehydrogenase; Male; Non-alcoholic Fatty Liver Disease; Organophosphonates; Phenols; Primary Cell Culture; Pyridazines; Rats; Thyroid Hormone Receptors beta; Transcription, Genetic; Uracil | 2020 |
Efficacy of delayed brincidofovir treatment against a lethal rabbitpox virus challenge in New Zealand White rabbits.
Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Body Temperature; Body Weight; Cytosine; Disease Models, Animal; Double-Blind Method; Organophosphonates; Poxviridae Infections; Rabbits; Smallpox; Survival Rate; Treatment Outcome; Vaccination; Vaccinia; Vaccinia virus; Variola virus; Viral Load | 2017 |
HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.
Topics: A549 Cells; Adenoviridae Infections; Adenovirus Infections, Human; Adenoviruses, Human; Animals; Antiviral Agents; Cell Line; Cidofovir; Cricetinae; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Immunosuppression Therapy; Liver; Male; Organophosphonates; Valganciclovir; Viral Load; Virus Replication | 2017 |
Induction, treatment and prevention of eczema vaccinatum in atopic dermatitis mouse models.
Topics: Animals; Antibodies, Viral; Antiviral Agents; CD4-Positive T-Lymphocytes; Cidofovir; Cytosine; Dermatitis, Atopic; Disease Models, Animal; Ectromelia virus; Female; Humans; Kaposi Varicelliform Eruption; Mice; Organophosphonates; Smallpox Vaccine | 2017 |
Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; HEK293 Cells; Humans; Immunocompromised Host; Mesocricetus; Organophosphonates; Valganciclovir; Viral Load; Virus Replication | 2017 |
Mitochondrial Uncoupling Attenuates Age-Dependent Neurodegeneration in C. elegans.
Topics: 2,4-Dinitrophenol; Aging; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Disease Models, Animal; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Uncoupling Proteins; Mitophagy; Mutation; Neurodegenerative Diseases; Organophosphonates; Piperazines | 2017 |
Fingolimod reduces neuropathic pain behaviors in a mouse model of multiple sclerosis by a sphingosine-1 phosphate receptor 1-dependent inhibition of central sensitization in the dorsal horn.
Topics: Anilides; Animals; Central Nervous System Sensitization; Disease Models, Animal; eIF-2 Kinase; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Motor Activity; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neuralgia; Organophosphonates; Oxadiazoles; Pain Threshold; Peptide Fragments; Receptors, Lysosphingolipid; Sphingosine-1-Phosphate Receptors; Spinal Cord; Spinal Nerve Roots; Subcellular Fractions; Thiophenes | 2018 |
Lytic viral replication and immunopathology in a cytomegalovirus-induced mouse model of secondary hemophagocytic lymphohistiocytosis.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Dexamethasone; Disease Models, Animal; Humans; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Lymphohistiocytosis, Hemophagocytic; Mice; Mice, Inbred BALB C; Mice, Knockout; Muromegalovirus; Organophosphonates; T-Lymphocytes; Toll-Like Receptor 3; Toll-Like Receptor 9; Virus Diseases; Virus Replication | 2017 |
The Sphingosine 1-Phosphate Analogue FTY720 Alleviates Seizure-induced Overexpression of P-Glycoprotein in Rat Hippocampus.
Topics: Anilides; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclooxygenase 2; Disease Models, Animal; Drug Resistant Epilepsy; Fingolimod Hydrochloride; Hippocampus; Humans; Immunosuppressive Agents; Injections, Intraperitoneal; Lysophospholipids; Male; Organophosphonates; Phenytoin; Pilocarpine; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Sphingosine; Sphingosine-1-Phosphate Receptors; Up-Regulation | 2018 |
USC-087 protects Syrian hamsters against lethal challenge with human species C adenoviruses.
Topics: Adenine; Adenovirus Infections, Human; Adenoviruses, Human; Administration, Oral; Animals; Antiviral Agents; Disease Models, Animal; Immunocompromised Host; Liver; Mesocricetus; Organophosphonates; Prodrugs; Survival Analysis; Treatment Outcome; Tyrosine | 2018 |
The spectre of smallpox lingers.
Topics: Animals; Benzamides; Cytosine; Disease Eradication; Disease Models, Animal; Disease Reservoirs; Drug Approval; Female; History, 20th Century; History, 21st Century; Humans; Isoindoles; Organophosphonates; Rabbits; Smallpox; Smallpox Vaccine; Synthetic Biology; United States; United States Food and Drug Administration | 2018 |
Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.
Topics: Aminobutyrates; Animals; Disease Models, Animal; Fluorouracil; gamma-Glutamyltransferase; Humans; Mice; Neoplasms; Organophosphonates; Reactive Oxygen Species; Stomatitis | 2019 |
Mannose 6-phosphonate labelling: A key for processing the therapeutic enzyme in Pompe disease.
Topics: Adult; Animals; Cells, Cultured; Disease Models, Animal; Glycogen Storage Disease Type II; Humans; Lysosomes; Mannose; Mice; Muscle, Skeletal; Myoblasts; Organophosphonates | 2019 |
A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia.
Topics: Animals; Autophagy; Disease Models, Animal; Fatty Acids; Fatty Liver; Glucose-6-Phosphatase; Glycogen; Glycogen Storage Disease Type I; Liver; Mice; Mice, Knockout; Mitochondria, Liver; Organelle Biogenesis; Organophosphonates; Oxidation-Reduction; Thyroid Hormone Receptors beta; Triglycerides | 2019 |
Role of phospholipase A₂ (PLA₂) inhibitors in attenuating apoptosis of the corneal epithelial cells and mitigation of Acanthamoeba keratitis.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Animals; Apoptosis; Arachidonic Acids; Blotting, Western; Cells, Cultured; Chemokine CXCL2; Chromatography, High Pressure Liquid; Conjunctiva; Cricetinae; Cricetulus; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epithelium, Corneal; Mannose; Organophosphonates; Phospholipases A2, Cytosolic; Protozoan Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation | 2013 |
Safety of cidofovir by intratympanic delivery technique.
Topics: Animals; Antiviral Agents; Cidofovir; Cochlea; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Guinea Pigs; Hearing Loss, Sensorineural; Injections; Organophosphonates | 2014 |
Vaginally delivered tenofovir disoproxil fumarate provides greater protection than tenofovir against genital herpes in a murine model of efficacy and safety.
Topics: Adenine; Administration, Intravaginal; Animals; Antiviral Agents; Contraceptive Devices, Female; Disease Models, Animal; Drug Administration Schedule; Female; Herpes Genitalis; Herpesvirus 2, Human; Humans; Mice; Mice, Inbred BALB C; Organophosphonates; Survival Analysis; Tenofovir; Vagina; Vaginal Creams, Foams, and Jellies | 2014 |
Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cidofovir; Cytosine; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Resistance, Viral; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Mice; Mice, Nude; Organophosphonates; Phenotype; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2013 |
In vitro efficacy of brincidofovir against variola virus.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Organophosphonates; Smallpox; Variola virus | 2014 |
Alteration of basilar artery rho-kinase and soluble guanylyl cyclase protein expression in a rat model of cerebral vasospasm following subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Behavior, Animal; Cyclic AMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Endothelin-1; Guanylate Cyclase; Male; Organ Specificity; Organophosphonates; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Transport; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; rho-Associated Kinases; Signal Transduction; Soluble Guanylyl Cyclase; Subarachnoid Hemorrhage; Tetrazoles; Vasospasm, Intracranial | 2014 |
HIV pre-exposure prophylaxis: mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model.
Topics: Adenine; Animals; Anti-HIV Agents; Cyclohexanes; Disease Models, Animal; Female; HIV Infections; HIV-1; Humans; Maraviroc; Mice; Mucous Membrane; Organophosphonates; Pre-Exposure Prophylaxis; Reverse Transcriptase Inhibitors; Tenofovir; Triazoles; Virus Internalization | 2014 |
Prophylactic treatment with a novel bioadhesive gel formulation containing aciclovir and tenofovir protects from HSV-2 infection.
Topics: Acrylic Resins; Acyclovir; Adenine; Animals; Anti-Infective Agents; Chlorocebus aethiops; Disease Models, Animal; Drug-Related Side Effects and Adverse Reactions; Female; Herpes Genitalis; Herpesvirus 2, Human; Mice, Inbred BALB C; Organophosphonates; Poloxamer; Rabbits; Rats, Sprague-Dawley; Tenofovir; Treatment Outcome; Vaginal Creams, Foams, and Jellies; Vero Cells | 2014 |
Enhanced efficacy of cidofovir combined with vaccinia immune globulin in treating progressive cutaneous vaccinia virus infections in immunosuppressed hairless mice.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Female; Immunoglobulins; Infusions, Parenteral; Mice, Hairless; Mice, SCID; Organophosphonates; Skin Diseases, Infectious; Treatment Outcome; Vaccinia | 2015 |
Papiine herpesvirus 2 as a predictive model for drug sensitivity of Macacine herpesvirus 1 (monkey B virus).
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Cercopithecine; Macaca mulatta; Mice; Organophosphonates; Simplexvirus; Trifluridine; Vero Cells; Viral Plaque Assay | 2014 |
Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Alanine Transaminase; Animals; Body Weight; Cell Line; Cidofovir; Cytosine; Disease Models, Animal; Female; Humans; Immunocompromised Host; Liver; Mesocricetus; Organophosphonates; Ribavirin; Survival Analysis; Treatment Outcome; Viral Load | 2014 |
A cationic-independent mannose 6-phosphate receptor inhibitor (PXS64) ameliorates kidney fibrosis by inhibiting activation of transforming growth factor-β1.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Humans; Kidney; Kidney Tubules; Male; Mannosides; Mice, Inbred C57BL; Neutrophils; Organophosphonates; Prodrugs; Smad2 Protein; Transforming Growth Factor beta; Ureteral Obstruction | 2015 |
Carbamoylphosphonates inhibit autotaxin and metastasis formation in vivo.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Structure; Organophosphonates; Phosphoric Diester Hydrolases; Structure-Activity Relationship; Sulfonamides | 2015 |
The efficacy and pharmacokinetics of brincidofovir for the treatment of lethal rabbitpox virus infection: a model of smallpox disease.
Topics: Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Injections, Intradermal; Organophosphonates; Rabbits; Random Allocation; Smallpox; Vaccinia; Vaccinia virus; Variola virus | 2015 |
MRI visible drug eluting magnetic microspheres for transcatheter intra-arterial delivery to liver tumors.
Topics: Adenine; Alginates; Animals; Antineoplastic Agents; Disease Models, Animal; Drug Carriers; Glucuronic Acid; Hexuronic Acids; Injections, Intra-Arterial; Liver Neoplasms; Magnetic Resonance Imaging; Microspheres; Naphthalimides; Organophosphonates; Rats | 2015 |
A quantitative multiplex nuclease protection assay reveals immunotoxicity gene expression profiles in the rabbit model for vaginal drug safety evaluation.
Topics: Adenine; Animals; Anti-HIV Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Female; Host-Pathogen Interactions; Immunohistochemistry; Inflammation; Interleukin-1beta; Interleukin-8; Mucous Membrane; Nonoxynol; Nuclease Protection Assays; Oligopeptides; Organophosphonates; Rabbits; Tenofovir; Toll-Like Receptor 4; Transcriptome; Vagina | 2015 |
Early Initiation of Antiretroviral Therapy Can Functionally Control Productive HIV-1 Infection in Humanized-BLT Mice.
Topics: Adenine; Animals; Anti-HIV Agents; Antigens, CD34; Bone Marrow; CD8-Positive T-Lymphocytes; Disease Models, Animal; Disease Progression; DNA, Viral; Gene Dosage; HIV Infections; HIV-1; Humans; Liver; Mice; Mice, Inbred NOD; Mice, Transgenic; Organophosphonates; Pilot Projects; RNA, Viral; Spleen; Tenofovir; Thymus Gland; Viral Load; Virus Replication | 2015 |
The alkynylphosphonate analogue of calcitriol EM1 has potent anti-metastatic effects in breast cancer.
Topics: Animals; Breast Neoplasms; Calcitriol; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Organophosphonates | 2015 |
In Vitro and In Vivo Evaluation of Cidofovir as a Topical Ophthalmic Antiviral for Ocular Canine Herpesvirus-1 Infections in Dogs.
Topics: Administration, Ophthalmic; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Dog Diseases; Dogs; Herpesviridae Infections; Herpesvirus 1, Canid; Madin Darby Canine Kidney Cells; Microscopy, Confocal; Organophosphonates; Random Allocation; Vero Cells; Virus Shedding | 2015 |
Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cyclin D1; Disease Models, Animal; Enzyme Activation; Humans; Inhibitor of Apoptosis Proteins; Isoxazoles; Male; Mice; Mice, Nude; Neoplasm Metastasis; Neovascularization, Pathologic; Organophosphonates; Prostatic Neoplasms; Tetrazoles; Ubiquitin-Protein Ligases; Xenograft Model Antitumor Assays | 2016 |
GGsTop, a novel and specific γ-glutamyl transpeptidase inhibitor, protects hepatic ischemia-reperfusion injury in rats.
Topics: Alanine Transaminase; Aldehydes; Aminobutyrates; Animals; Aspartate Aminotransferases; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Interleukin-1beta; Liver; Liver Diseases; Male; Malondialdehyde; Necrosis; Organophosphonates; Oxidative Stress; Rats, Wistar; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2016 |
Effect of high-dose vocal fold injection of cidofovir and bevacizumab in a porcine model.
Topics: Animals; Bevacizumab; Biopsy, Needle; Cidofovir; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Immunohistochemistry; Injections, Intralesional; Laryngeal Neoplasms; Odds Ratio; Organophosphonates; Papilloma; Random Allocation; Sensitivity and Specificity; Sus scrofa; Vocal Cords | 2017 |
Buccal viral DNA as a trigger for brincidofovir therapy in the mousepox model of smallpox.
Topics: Animals; Antiviral Agents; Cytosine; Disease Models, Animal; DNA, Viral; Ectromelia virus; Ectromelia, Infectious; Mice; Mouth Mucosa; Organophosphonates; Orthopoxvirus; Smallpox | 2017 |
Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects.
Topics: Adenine; Age Factors; Animals; Anti-HIV Agents; Disease Models, Animal; Female; HIV Infections; HIV-1; Humans; Macaca mulatta; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Time Factors; Treatment Outcome | 2008 |
Antiviral effects of lamivudine, emtricitabine, adefovir dipivoxil, and tenofovir disoproxil fumarate administered orally alone and in combination to woodchucks with chronic woodchuck hepatitis virus infection.
Topics: Adenine; Animals; Antigens, Viral; Antiviral Agents; Deoxycytidine; Disease Models, Animal; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Hepatitis B Virus, Woodchuck; Hepatitis B, Chronic; Humans; Lamivudine; Liver; Marmota; Organophosphonates; RNA, Viral; Rodent Diseases; Tenofovir; Virus Replication | 2008 |
Assessing the efficacy of cidofovir against herpesvirus-induced genital lesions in goats using different therapeutic regimens.
Topics: Animals; Antiviral Agents; Base Sequence; Cidofovir; Cytosine; Disease Models, Animal; DNA Primers; DNA, Viral; Female; Genital Diseases, Female; Goat Diseases; Goats; Herpes Genitalis; Herpesviridae Infections; Humans; Organophosphonates; Species Specificity; Vaginal Creams, Foams, and Jellies; Varicellovirus | 2008 |
Bisphosphonated fluoroquinolone esters as osteotropic prodrugs for the prevention of osteomyelitis.
Topics: Animals; Disease Models, Animal; Esters; Female; Fluoroquinolones; Humans; Molecular Structure; Organophosphonates; Osteomyelitis; Prodrugs; Rats | 2008 |
Synthesis and biological evaluation of a series of liver-selective phosphonic acid thyroid hormone receptor agonists and their prodrugs.
Topics: Animals; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Glycerolphosphate Dehydrogenase; Hypercholesterolemia; Ligands; Liver; Molecular Structure; Organophosphonates; Prodrugs; Rats; Rats, Sprague-Dawley; Receptors, Thyroid Hormone; Stereoisomerism; Structure-Activity Relationship | 2008 |
Experimental infection of an African dormouse (Graphiurus kelleni) with monkeypox virus.
Topics: Animal Structures; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Hemorrhage; Humans; Monkeypox virus; Mpox (monkeypox); Myoxidae; Necrosis; Organophosphonates; Smallpox Vaccine | 2009 |
Using biomarkers to stage disease progression in a lethal mousepox model treated with CMX001.
Topics: Alanine Transaminase; Animals; Antiviral Agents; Aspartate Aminotransferases; Biomarkers; Cell Line; Cytosine; Disease Models, Animal; Disease Progression; DNA, Viral; Ectromelia virus; Ectromelia, Infectious; Female; Humans; Interferon-gamma; Mice; Organophosphonates; Treatment Outcome; Weight Loss | 2008 |
Mousepox in the C57BL/6 strain provides an improved model for evaluating anti-poxvirus therapies.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytokines; Cytosine; Disease Models, Animal; Ectromelia virus; Ectromelia, Infectious; Female; Mice; Mice, Inbred C57BL; Organophosphonates | 2009 |
Clinical evaluation of local ocular toxicity in candidate anti-adenoviral agents in vivo.
Topics: Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Eyelids; Female; Lacrimal Apparatus; Ophthalmic Solutions; Organophosphonates; Rabbits | 2009 |
Initiation of antiretroviral therapy 48 hours after infection with simian immunodeficiency virus potently suppresses acute-phase viremia and blocks the massive loss of memory CD4+ T cells but fails to prevent disease.
Topics: Adenine; Amino Acid Sequence; Animals; Anti-HIV Agents; CD4-Positive T-Lymphocytes; Cells, Cultured; Disease Models, Animal; Drug Administration Schedule; HIV Antibodies; HIV Infections; Humans; Injections; Macaca mulatta; Molecular Sequence Data; Organophosphonates; Sequence Alignment; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Time Factors; Viremia; Virus Replication | 2009 |
The in vitro and in vivo evaluation of ddC as a topical antiviral for ocular adenovirus infections.
Topics: Adenoviridae Infections; Adenoviruses, Human; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Female; Humans; Organophosphonates; Rabbits; Tumor Cells, Cultured; Viral Plaque Assay; Virus Replication; Zalcitabine | 2009 |
Mechanisms of toxic smoke inhalation and burn injury: role of neutral endopeptidase and vascular leakage in mice.
Topics: Animals; Burns; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Neprilysin; Organophosphonates; Phenylalanine; Protease Inhibitors; Pulmonary Edema; Smoke Inhalation Injury | 2009 |
Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation.
Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cathepsin G; Chymases; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Female; Injections, Intravenous; Lung Diseases; Mice; Organophosphonates; Piperidines; Pulmonary Disease, Chronic Obstructive; Rats; Sheep; Treatment Outcome | 2010 |
Susceptibility to genital herpes as a biomarker predictive of increased HIV risk: expansion of a murine model of microbicide safety.
Topics: Adenine; Administration, Intravaginal; Animals; Anti-Infective Agents; Antiviral Agents; Biomarkers; Disease Models, Animal; Disease Susceptibility; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; Mice; Mice, Inbred BALB C; Naphthalenesulfonates; Nonoxynol; Organophosphonates; Polymers; Predictive Value of Tests; Risk Assessment; Tenofovir | 2009 |
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics.
Topics: Adenosine Monophosphate; Animals; Benzimidazoles; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Design; Enzyme Inhibitors; Fructose-Bisphosphatase; Humans; Liver; Molecular Structure; Organophosphonates; Rats; Rats, Zucker; Stereoisomerism; Structure-Activity Relationship | 2010 |
A mouse model of lethal infection for evaluating prophylactics and therapeutics against Monkeypox virus.
Topics: Animals; Antiviral Agents; Benzamides; Cytosine; Disease Models, Animal; Female; Humans; Isoindoles; Liver; Lung; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Monkeypox virus; Mpox (monkeypox); Organophosphonates; Smallpox Vaccine; Spleen; STAT1 Transcription Factor; Survival Analysis; Treatment Outcome; Vaccinia virus; Viral Load | 2010 |
Findings in humanized-mouse model suggest benefit of further studies in HIV pre-exposure prophylaxis.
Topics: Adenine; Animals; Anti-HIV Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Deoxycytidine; Disease Models, Animal; Drug Combinations; Emtricitabine; Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Antibodies; HIV Infections; Humans; Infection Control; Liver Transplantation; Mice; Occupational Exposure; Organophosphonates; Organophosphorus Compounds; Tenofovir; Thymus Gland; Transplantation Chimera | 2010 |
Clinical and antiviral efficacy of an ophthalmic formulation of dexamethasone povidone-iodine in a rabbit model of adenoviral keratoconjunctivitis.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Anti-Infective Agents, Local; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Ophthalmic Solutions; Organophosphonates; Pharmaceutical Preparations; Povidone-Iodine; Rabbits; Tobramycin; Treatment Outcome; Viral Plaque Assay | 2011 |
Cidofovir does not prevent caprine herpesvirus type-1 neural latency in goats.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Female; Ganglia; Goats; Herpesviridae Infections; Humans; Organophosphonates; Sacrococcygeal Region; Varicellovirus; Virus Latency; Virus Shedding | 2010 |
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis.
Topics: Adenosine Triphosphate; Animals; Benzhydryl Compounds; Benzofurans; Cresols; Cystitis; Disease Models, Animal; Down-Regulation; Female; Hydrochloric Acid; Mandelic Acids; N-Methylscopolamine; Organophosphonates; Phenols; Phenylpropanolamine; Pirenzepine; Polycyclic Compounds; Pyridoxal Phosphate; Pyrrolidines; Quinuclidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urination; Urodynamics | 2010 |
Efficacy of CMX001 against herpes simplex virus infections in mice and correlations with drug distribution studies.
Topics: Administration, Oral; Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Herpes Simplex; Herpesvirus 1, Human; Herpesvirus 2, Human; Mice; Mice, Inbred BALB C; Organophosphonates; Tissue Distribution | 2010 |
Oral hexadecyloxypropyl-cidofovir therapy in pregnant guinea pigs improves outcome in the congenital model of cytomegalovirus infection.
Topics: Administration, Oral; Animals; Antiviral Agents; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Organophosphonates; Pregnancy; Treatment Outcome | 2011 |
Role for peroxynitrite in sphingosine-1-phosphate-induced hyperalgesia in rats.
Topics: Acetophenones; Anilides; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Hyperalgesia; Lysophospholipids; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Organophosphonates; Oxadiazoles; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Lysosphingolipid; Sphingosine; Thiophenes; Time Factors | 2011 |
Generation and mucosal transmissibility of emtricitabine- and tenofovir-resistant SHIV162P3 mutants in macaques.
Topics: Adenine; Animals; Anti-HIV Agents; Deoxycytidine; Disease Models, Animal; Drug Resistance, Viral; Emtricitabine; HIV; Humans; Macaca; Mutation; Organophosphonates; Recombination, Genetic; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Virus Cultivation | 2011 |
Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Enzyme Inhibitors; Humans; Liver Neoplasms; Melanoma, Experimental; Mice; Multienzyme Complexes; Naphthalenes; Neoplasm Invasiveness; Neoplasm Metastasis; Organophosphonates; Organophosphorus Compounds; Phosphodiesterase I; Phosphoric Diester Hydrolases; Pyrophosphatases | 2011 |
Methoxyethylamino-numonafide is an efficacious and minimally toxic amonafide derivative in murine models of human cancer.
Topics: Adenine; Animals; Antineoplastic Agents; Cell Line; Disease Models, Animal; Gene Expression Profiling; Humans; Liver Neoplasms, Experimental; Mice; Mice, Nude; Naphthalimides; Organophosphonates; Stomach Neoplasms; Transplantation, Heterologous | 2011 |
One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates.
Topics: Adenine; Administration, Topical; Animals; Base Sequence; CD4-Positive T-Lymphocytes; Chimera; Disease Models, Animal; DNA Primers; Drug Evaluation, Preclinical; Female; HIV Infections; Humans; Mice; Organophosphonates; Receptors, CCR5; Reverse Transcriptase Inhibitors; Tenofovir; Vagina | 2011 |
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir.
Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine | 2011 |
Biodefence since 9/11: The price of protection.
Topics: Animals; Antiviral Agents; Biomedical Research; Bioterrorism; Budgets; Cytosine; Disease Models, Animal; Humans; Male; Organophosphonates; Security Measures; September 11 Terrorist Attacks; Smallpox; Tularemia; United States; Vaccines; Young Adult | 2011 |
Preventive effect of GGsTop, a novel and selective γ-glutamyl transpeptidase inhibitor, on ischemia/reperfusion-induced renal injury in rats.
Topics: Acute Kidney Injury; Aminobutyrates; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; gamma-Glutamyltransferase; Glutathione; Kidney Function Tests; Male; Malondialdehyde; Molecular Targeted Therapy; Organophosphonates; Oxygen; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxides; Time Factors | 2011 |
Intraocular safety and pharmacokinetics of hexadecyloxypropyl-cidofovir (HDP-CDV) as a long-lasting intravitreal antiviral drug.
Topics: Animals; Chromatography, High Pressure Liquid; Ciliary Body; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Disease Models, Animal; Dose-Response Relationship, Drug; Follow-Up Studies; Hydrolysis; Intravitreal Injections; Organophosphonates; Rabbits; Retina; Vitreous Body | 2011 |
Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring.
Topics: Acyclovir; Adenine; Administration, Intravaginal; Animals; Anti-HIV Agents; Antiviral Agents; Delayed-Action Preparations; Disease Models, Animal; Drug Combinations; Drug Delivery Systems; Equipment Design; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Organophosphonates; Rabbits; Sexually Transmitted Diseases, Viral; Tenofovir; Treatment Outcome | 2012 |
Evaluation of inhaled cidofovir as postexposure prophylactic in an aerosol rabbitpox model.
Topics: Administration, Inhalation; Animals; Antiviral Agents; Cell Line; Cidofovir; Cytosine; Disease Models, Animal; Female; Lung; Male; Organophosphonates; Post-Exposure Prophylaxis; Rabbits; Vaccinia; Vaccinia virus | 2012 |
Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox.
Topics: Animals; Benzamides; Biomarkers, Pharmacological; Cell Line; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Ectromelia virus; Ectromelia, Infectious; Female; Humans; Isoindoles; Mice; Mice, Hairless; Mice, Inbred C57BL; Monkeypox virus; Organophosphonates; Smallpox; Variola virus; Virus Replication | 2012 |
A single cidofovir treatment rescues animals at progressive stages of lethal orthopoxvirus disease.
Topics: Animals; Antibodies, Viral; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Ectromelia virus; Ectromelia, Infectious; Female; Immunoglobulin G; Interferon-gamma; Mice; Mice, Inbred BALB C; Organophosphonates; Survival Analysis | 2012 |
Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal.
Topics: Adenine; Alleles; Animals; Antibodies, Viral; Antibody Formation; Antiviral Agents; CD4 Lymphocyte Count; CD8-Positive T-Lymphocytes; Disease Models, Animal; Genes, MHC Class I; Genotyping Techniques; Immunity, Cellular; Lymphocyte Activation; Macaca mulatta; Neutralization Tests; Organophosphonates; RNA-Directed DNA Polymerase; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Time Factors; Treatment Outcome; Viremia; Virus Replication | 2012 |
Double oral administration of emtricitabine/tenofovir prior to virus exposure protects against highly pathogenic simian/human immunodeficiency virus infection in macaques.
Topics: Adenine; Administration, Oral; Animals; Anti-HIV Agents; Antibiotic Prophylaxis; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Deoxycytidine; Disease Models, Animal; Emtricitabine; Humans; Macaca; Organophosphonates; Simian Acquired Immunodeficiency Syndrome; Tenofovir; Viral Load | 2012 |
Antiviral and immunological effects of tenofovir microbicide in vaginal herpes simplex virus 2 infection.
Topics: Adenine; Administration, Topical; Animals; Anti-Infective Agents; Antiviral Agents; Cells, Cultured; Disease Models, Animal; Female; Herpes Genitalis; Interferon-gamma; Interleukin-2; Mice; Mice, Inbred C57BL; Organophosphonates; Tenofovir; Tumor Necrosis Factor-alpha; Vagina; Vaginal Creams, Foams, and Jellies; Virus Shedding | 2012 |
Carbodiimides in the synthesis of enamino- and α-aminophosphonates as peptidomimetics of analgesic/antiinflammatory and anticancer agents.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carbodiimides; Cell Line, Tumor; Disease Models, Animal; Drug Stability; Humans; Inflammation; Male; Mice; Neoplasms; Organophosphonates; Pain; Peptidomimetics; Structure-Activity Relationship | 2012 |
Blocking the natural killer cell inhibitory receptor NKG2A increases activity of human natural killer cells and clears hepatitis B virus infection in mice.
Topics: Adenine; Adult; Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Female; Flow Cytometry; Hepatitis B Antibodies; Hepatitis B virus; Hepatitis B, Chronic; Histocompatibility Antigens Class I; Humans; Immunohistochemistry; Immunosuppressive Agents; Killer Cells, Natural; Male; Mice; Mice, Inbred C57BL; NK Cell Lectin-Like Receptor Subfamily C; Organophosphonates; Viral Load | 2013 |
Inefficient vaginal transmission of tenofovir-resistant HIV-1.
Topics: Adenine; Animals; Anti-HIV Agents; Disease Models, Animal; Drug Resistance, Viral; Female; Genotype; HIV Infections; HIV-1; Humans; Mice; Mucous Membrane; Mutation, Missense; Organophosphonates; Suppression, Genetic; Tenofovir; Vagina | 2013 |
The amino acid substitutions rtP177G and rtF249A in the reverse transcriptase domain of hepatitis B virus polymerase reduce the susceptibility to tenofovir.
Topics: Adenine; Amino Acid Substitution; Animals; Antiviral Agents; Computational Biology; Disease Models, Animal; Drug Resistance, Viral; Female; Hepatitis B; Hepatitis B virus; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Mutant Proteins; Organophosphonates; RNA-Directed DNA Polymerase; Tenofovir | 2013 |
5'-Phosphate and 5'-phosphonate ester derivatives of (N)-methanocarba adenosine with in vivo cardioprotective activity.
Topics: Adenosine; Animals; Cardiotonic Agents; Chromatography, High Pressure Liquid; Disease Models, Animal; Esters; Magnetic Resonance Spectroscopy; Mice; Myocardial Ischemia; Organophosphonates; Phosphates; Spectrometry, Mass, Electrospray Ionization | 2013 |
Pharmacokinetic and antiretroviral activity in mice of oral [P(1),P(2)-bis[2-(adenin-9-yl)ethoxymethyl]phosphonate], a prodrug of 9-(2-phosphonylmethoxyethyl)adenine.
Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Biological Availability; Blood Cell Count; Chromatography, High Pressure Liquid; Disease Models, Animal; DNA, Viral; Female; Humans; Injections, Intraperitoneal; Lymph Nodes; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Organophosphonates; Polymerase Chain Reaction; Prodrugs; Retroviridae; Retroviridae Infections; Tumor Cells, Cultured | 2002 |
Topical administration of low-dose tenofovir disoproxil fumarate to protect infant macaques against multiple oral exposures of low doses of simian immunodeficiency virus.
Topics: Adenine; Administration, Topical; Animals; Anti-HIV Agents; Disease Models, Animal; Macaca; Organophosphonates; Organophosphorus Compounds; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir | 2002 |
Isoflurane preconditioning reduces purkinje cell death in an in vitro model of rat cerebellar ischemia.
Topics: Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; Cell Death; Cell Survival; Cerebellar Diseases; Disease Models, Animal; Glyburide; Ischemic Preconditioning; Isoflurane; Male; Nerve Degeneration; Organ Culture Techniques; Organophosphonates; Potassium Channel Blockers; Purkinje Cells; Rats; Rats, Sprague-Dawley | 2003 |
Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA.
Topics: Adenine; Animals; Capsid; Combined Modality Therapy; Disease Models, Animal; Gene Expression Regulation, Viral; Genetic Therapy; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Lamivudine; Liver; Male; Mice; Mice, Inbred Strains; Organophosphonates; Reverse Transcriptase Inhibitors; RNA, Small Interfering; Specific Pathogen-Free Organisms; Virus Replication | 2003 |
HPMPC therapy of MCMV-induced retinal disease in the SCID mouse measured by electroretinography, a non-invasive technique.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Electroretinography; Eye Infections, Viral; Female; Herpesviridae Infections; Humans; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Retina; Treatment Outcome; Virus Replication | 2003 |
Efficacy of multiple- or single-dose cidofovir against vaccinia and cowpox virus infections in mice.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; Drug Administration Schedule; Drug Resistance, Viral; Female; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Vaccinia; Vero Cells | 2003 |
The cotton rat model for adenovirus ocular infection: antiviral activity of cidofovir.
Topics: Adenoviridae Infections; Adenoviruses, Human; Administration, Topical; Animals; Antigens, Viral; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cornea; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Eye Infections, Viral; Female; Organophosphonates; Organophosphorus Compounds; Rats; Sigmodontinae; Viral Plaque Assay; Virus Replication; Virus Shedding | 2004 |
Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Ectromelia virus; Ectromelia, Infectious; Esters; Female; Inhibitory Concentration 50; Mice; Molecular Structure; Organophosphonates; Organophosphorus Compounds | 2004 |
Efficacy of cidofovir in a murine model of disseminated progressive vaccinia.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; DNA, Viral; Mice; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Skin; Vaccinia; Vaccinia virus | 2004 |
Cutaneous infections of mice with vaccinia or cowpox viruses and efficacy of cidofovir.
Topics: Administration, Cutaneous; Animals; Antiviral Agents; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; Mice; Organophosphonates; Organophosphorus Compounds; Orthopoxvirus; Vaccinia; Vaccinia virus | 2004 |
Efficacy of ganciclovir and cidofovir against human cytomegalovirus replication in SCID mice implanted with human retinal tissue.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Transplantation, Heterologous; Virus Replication | 2004 |
Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infection.
Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Esters; Ether; Humans; Lipids; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Prodrugs; Treatment Outcome | 2004 |
Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model.
Topics: Adenine; Administration, Oral; Amino Acid Motifs; Amino Acid Substitution; Animals; Antiviral Agents; Disease Models, Animal; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Drug Therapy, Combination; Hepatitis B; Hepatitis B Virus, Woodchuck; Lamivudine; Marmota; Mutation, Missense; Organophosphonates; Protein Structure, Tertiary; Viremia; Virus Replication | 2004 |
Topical cidofovir is more effective than is parenteral therapy for treatment of progressive vaccinia in immunocompromised mice.
Topics: Administration, Topical; Animals; Antiviral Agents; Brain; Cidofovir; Cyclophosphamide; Cytosine; Disease Models, Animal; Female; Immunocompromised Host; Immunosuppressive Agents; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Hairless; Organophosphonates; Organophosphorus Compounds; Skin; Specific Pathogen-Free Organisms; Spleen; Survival Analysis; Time Factors; Vaccinia; Viral Plaque Assay | 2004 |
Development of Vgamma2Vdelta2+ T cell responses during active mycobacterial coinfection of simian immunodeficiency virus-infected macaques requires control of viral infection and immune competence of CD4+ T cells.
Topics: Adenine; Amino Acid Sequence; Animals; Cattle; CD4-Positive T-Lymphocytes; Disease Models, Animal; Drug Therapy, Combination; HIV Protease Inhibitors; Indinavir; Lung; Lymphocyte Count; Macaca mulatta; Macaca nemestrina; Molecular Sequence Data; Mycobacterium bovis; Organophosphonates; Receptors, Antigen, T-Cell, gamma-delta; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Tuberculosis, Bovine | 2004 |
Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes.
Topics: Adenine; Animals; Antiviral Agents; Disease Models, Animal; DNA, Circular; DNA, Viral; Hepatitis B, Chronic; Hepatocytes; Mice; Organophosphonates; Transplantation, Heterologous; Tupaia; Urokinase-Type Plasminogen Activator | 2005 |
Role of the endothelin system in secondary pulmonary hypertension related to air embolism: lessons learned from testing four classes of endothelin blockers in a rat model.
Topics: Acute Disease; Animals; Aspartic Acid Endopeptidases; Atrasentan; Benzofurans; Cardiovascular Agents; Disease Models, Animal; Embolism, Air; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-Converting Enzymes; Endothelins; Hemodynamics; Hypertension, Pulmonary; Male; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Sulfonamides; Time Factors; Ventricular Dysfunction, Right | 2004 |
Triple vasopeptidase inhibition of angiotensin-converting enzyme/neutral endopeptidase/endothelin-converting enzyme activities on the hemodynamic profile of chronically instrumented unrestrained conscious spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Benzazepines; Benzofurans; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelin-Converting Enzymes; Heart Rate; Hypertension; Infusions, Intra-Arterial; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Rats; Rats, Inbred SHR; Time Factors | 2004 |
CGS 26303 upregulates mRNA expression of heme oxygenase-1 in brain tissue of rats subjected to experimental subarachnoid hemorrhage.
Topics: Animals; Aspartic Acid Endopeptidases; Brain; Disease Models, Animal; Endothelin-Converting Enzymes; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); HSP70 Heat-Shock Proteins; Male; Metalloendopeptidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organophosphonates; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subarachnoid Hemorrhage; Tetrazoles; Up-Regulation; Vasospasm, Intracranial | 2004 |
Neuroprotective effect of CGS 26303, an endothelin-converting enzyme inhibitor, on transient middle cerebral artery occlusion in rats.
Topics: Animals; Aspartic Acid Endopeptidases; Behavior, Animal; Brain; Brain Edema; Disease Models, Animal; Drug Administration Schedule; Endothelin-Converting Enzymes; Infarction, Middle Cerebral Artery; Injections, Intravenous; Male; Metalloendopeptidases; Neuroprotective Agents; Organophosphonates; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Tetrazoles | 2004 |
Carbamoylphosphonate matrix metalloproteinase inhibitors 3: in vivo evaluation of cyclopentylcarbamoylphosphonic acid in experimental metastasis and angiogenesis.
Topics: Animals; Chemotaxis; Disease Models, Animal; Female; Humans; Lung Neoplasms; Matrix Metalloproteinase Inhibitors; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Organophosphonates | 2005 |
Characterization and treatment of cidofovir-resistant vaccinia (WR strain) virus infections in cell culture and in mice.
Topics: Animals; Cells, Cultured; Cidofovir; Cytosine; Disease Models, Animal; Drug Resistance; Mice; Mice, Inbred BALB C; Mice, SCID; Mutation; Organophosphonates; Vaccinia; Vaccinia virus; Virus Replication | 2005 |
The central nervous system is a viral reservoir in simian immunodeficiency virus--infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy.
Topics: Adenine; Animals; Anti-HIV Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Brain; Disease Models, Animal; DNA, Viral; Drug Therapy, Combination; Histocompatibility Antigens Class II; Injections, Subcutaneous; Macaca nemestrina; Organophosphonates; Polymerase Chain Reaction; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Time Factors; Zalcitabine | 2005 |
Cyclic cidofovir (cHPMPC) prevents congenital cytomegalovirus infection in a guinea pig model.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Infectious Disease Transmission, Vertical; Organophosphonates; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Outcome; Roseolovirus; Roseolovirus Infections | 2006 |
N-chlorotaurine is an effective antiviral agent against adenovirus in vitro and in the Ad5/NZW rabbit ocular model.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Infections, Viral; Female; Keratitis; Ophthalmic Solutions; Organophosphonates; Rabbits; Taurine; Viral Plaque Assay; Virus Replication | 2006 |
Effects of cidofovir treatment on cytokine induction in murine models of cowpox and vaccinia virus infection.
Topics: Animals; Antiviral Agents; Cidofovir; Cowpox; Cytokines; Cytosine; Disease Models, Animal; Female; Lung; Mice; Mice, Inbred BALB C; Organophosphonates; Vaccinia; Vaccinia virus | 2006 |
The effect of cidofovir on cytomegalovirus-induced hearing loss in a Guinea pig model.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Evoked Potentials, Auditory; Guinea Pigs; Hearing Loss; Organophosphonates; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.
Topics: Anilides; Animals; Capillary Permeability; Cells, Cultured; CHO Cells; Cricetinae; Disease Models, Animal; Evans Blue; Humans; Lymph Nodes; Lymphocytes; Lysophospholipids; Mice; Mice, Inbred C57BL; Models, Biological; Organophosphonates; Phenotype; Pulmonary Edema; Receptors, Lysosphingolipid; Sphingosine; Stereoisomerism | 2006 |
Chemoprophylaxis of HIV infection: moving forward with caution.
Topics: Adenine; Animals; Antiviral Agents; Chemoprevention; Disease Models, Animal; HIV Infections; HIV-1; Humans; Macaca mulatta; Organophosphonates; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir | 2006 |
Chemoprophylaxis with tenofovir disoproxil fumarate provided partial protection against infection with simian human immunodeficiency virus in macaques given multiple virus challenges.
Topics: Adenine; Animals; Anti-HIV Agents; Chemoprevention; Disease Models, Animal; Drug Resistance, Viral; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Macaca mulatta; Male; Organophosphonates; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir | 2006 |
Mutations in the E9L polymerase gene of cidofovir-resistant vaccinia virus strain WR are associated with the drug resistance phenotype.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Female; Genes, Viral; Mice; Mice, Inbred BALB C; Mutation; Organophosphonates; Phenotype; Specific Pathogen-Free Organisms; Vaccinia; Vaccinia virus; Vero Cells | 2006 |
A rapid and sensitive real-time PCR assay for the K65R drug resistance mutation in SIV reverse transcriptase.
Topics: Adenine; Animals; Disease Models, Animal; Drug Resistance, Viral; Macaca; Microbial Sensitivity Tests; Organophosphonates; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Sensitivity and Specificity; Simian Immunodeficiency Virus; Tenofovir | 2006 |
Cidofovir is effective against caprine herpesvirus 1 infection in goats.
Topics: Animals; Cidofovir; Cytosine; Disease Models, Animal; Goats; Herpesviridae Infections; Organophosphonates; Varicellovirus; Virus Shedding | 2007 |
Attenuation of experimental subarachnoid hemorrhage-induced increases in circulating intercellular adhesion molecule-1 and cerebral vasospasm by the endothelin-converting enzyme inhibitor CGS 26303.
Topics: Animals; Aspartic Acid Endopeptidases; Disease Models, Animal; E-Selectin; Endothelin-Converting Enzymes; Intercellular Adhesion Molecule-1; Male; Metalloendopeptidases; Organophosphonates; Rabbits; Subarachnoid Hemorrhage; Tetrazoles; Vascular Cell Adhesion Molecule-1; Vasospasm, Intracranial | 2007 |
Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection.
Topics: Adenine; Amino Acid Substitution; Animals; Anti-HIV Agents; CD8-Positive T-Lymphocytes; Disease Models, Animal; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Lymphocyte Depletion; Macaca; Mutation, Missense; Organophosphonates; RNA, Viral; Selection, Genetic; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Viral Load; Viremia | 2007 |
In vivo imaging of cidofovir treatment of cowpox virus infection.
Topics: Animals; Antiviral Agents; Bioterrorism; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; DNA Replication; Drug Evaluation, Preclinical; Female; Green Fluorescent Proteins; Humans; Image Processing, Computer-Assisted; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Organophosphonates; Recombination, Genetic; Smallpox; Treatment Outcome; Vero Cells; Virus Replication | 2007 |
A model of human cytomegalovirus infection in severe combined immunodeficient mice.
Topics: Animals; Antiviral Agents; Cell Culture Techniques; Cell Line; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Gelatin Sponge, Absorbable; Humans; Male; Mice; Mice, SCID; Organophosphonates; Viral Plaque Assay | 2007 |
Inhibition of non-Ras protein farnesylation reduces in-stent restenosis.
Topics: Aged; Animals; Cell Proliferation; Cells, Cultured; Coronary Restenosis; Disease Models, Animal; Drug-Eluting Stents; Endothelium, Vascular; Enzyme Inhibitors; Farnesyltranstransferase; Female; Humans; Male; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle Cells; Muscle, Smooth, Vascular; Organophosphonates; Phosphoric Acids; Platelet-Derived Growth Factor; Rabbits | 2008 |
Simian immunodeficiency virus infection induces severe loss of intestinal central memory T cells which impairs CD4+ T-cell restoration during antiretroviral therapy.
Topics: Adenine; Animals; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Disease Models, Animal; DNA, Viral; Emtricitabine; Flow Cytometry; Immunologic Memory; Lymphoid Tissue; Macaca mulatta; Organophosphonates; Polymerase Chain Reaction; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocyte Subsets; Tenofovir; Viral Load; Virus Replication; Zalcitabine | 2007 |
Direct stringency comparison of two macaque models (single-high vs. repeat-low) for mucosal HIV transmission using an identical anti-HIV chemoprophylaxis intervention.
Topics: Adenine; Administration, Rectal; Animals; Anti-HIV Agents; Antibodies, Viral; Chemoprevention; Disease Models, Animal; Macaca mulatta; Male; Organophosphonates; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir | 2007 |
Rabbitpox virus and vaccinia virus infection of rabbits as a model for human smallpox.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Humans; Organophosphonates; Poxviridae Infections; Rabbits; Smallpox; Survival Rate; Vaccinia; Vaccinia virus; Viremia | 2007 |
DNA polymerase mutations in drug-resistant herpes simplex virus mutants determine in vivo neurovirulence and drug-enzyme interactions.
Topics: Adenine; Animals; Antiviral Agents; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Enzyme Inhibitors; Exodeoxyribonucleases; Foscarnet; Genotype; Herpes Simplex; Herpesvirus 1, Human; Humans; Mice; Models, Molecular; Mutation; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Phenotype; Protein Binding; Protein Conformation; Vero Cells; Viral Proteins; Virulence | 2007 |
Efficacy of topical immunoglobulins against experimental adenoviral ocular infection.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Administration, Topical; Animals; Antiviral Agents; Cell Culture Techniques; Cidofovir; Conjunctiva; Cornea; Cytosine; Disease Models, Animal; Epithelial Cells; Eye Infections, Viral; Flow Cytometry; Immunoglobulins, Intravenous; Immunologic Factors; Keratoconjunctivitis; Organophosphonates; Rabbits; Treatment Outcome; Virus Cultivation; Virus Replication; Virus Shedding | 2007 |
Development of a novel mouse model to evaluate drug candidates against hepatitis B virus.
Topics: Adenine; Animals; Antiviral Agents; Cell Line; Disease Models, Animal; Drug Evaluation, Preclinical; Hepatitis B; Hepatitis B virus; Lamivudine; Mice; Mice, Nude; Organophosphonates; Reproducibility of Results; Tenofovir | 2007 |
Can the new humanized mouse model give HIV research a boost.
Topics: Adenine; Administration, Intravaginal; Animals; Deoxycytidine; Disease Models, Animal; Disease Susceptibility; Drug Evaluation, Preclinical; Emtricitabine; Female; Hematopoietic Stem Cell Transplantation; HIV Infections; HIV-1; Humans; Liver Transplantation; Macaca mulatta; Mice; Mice, Inbred NOD; Mice, Inbred Strains; Mice, SCID; Organophosphonates; Radiation Chimera; Species Specificity; Tenofovir; Thymus Gland; Transplantation, Heterologous | 2008 |
Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice.
Topics: Adenine; Administration, Intravaginal; Animals; Anti-HIV Agents; Deoxycytidine; Disease Models, Animal; Drug Evaluation, Preclinical; Emtricitabine; Female; Fetal Tissue Transplantation; Genitalia, Female; Hematopoietic Stem Cell Transplantation; HIV Infections; HIV-1; Humans; Immunity, Mucosal; Liver Transplantation; Mice; Mice, Inbred Strains; Mice, SCID; Organophosphonates; Radiation Chimera; Species Specificity; Tenofovir; Thymus Gland; Transplantation, Heterologous | 2008 |
Recovery of humoral immunity is critical for successful antiviral therapy in disseminated mouse adenovirus type 1 infection.
Topics: 3T3 Cells; Adenoviridae; Adenoviridae Infections; Animals; Antibodies, Viral; Antiviral Agents; Cell Line; Cidofovir; Cyclophosphamide; Cytosine; Disease Models, Animal; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, SCID; Organophosphonates; Treatment Outcome | 2008 |
The mu-opioid receptor agonist morphine, but not agonists at delta- or kappa-opioid receptors, induces peripheral antinociception mediated by cannabinoid receptors.
Topics: Amidohydrolases; Analgesics, Opioid; Animals; Arachidonic Acids; Benzamides; Benzomorphans; Cannabinoid Receptor Modulators; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperalgesia; Indoles; Male; Morphine; Organophosphonates; Pain; Pain Measurement; Piperazines; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2008 |
Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor.
Topics: Animals; Combinatorial Chemistry Techniques; Diabetes Mellitus; Disease Models, Animal; Drug Design; Drug Screening Assays, Antitumor; Haplorhini; Hydrocarbons, Halogenated; Mice; Molecular Structure; Naphthalenes; Neoplasms; Organophosphonates; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats | 2008 |
Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cricetinae; Cytosine; Disease Models, Animal; Drug Screening Assays, Antitumor; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Liver; Mesocricetus; Models, Biological; Organophosphonates | 2008 |
Inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine on visna virus infection in lambs: a model for in vivo testing of candidate anti-human immunodeficiency virus drugs.
Topics: Adenine; Animals; Antibodies, Viral; Antiviral Agents; Brain; Cytopathogenic Effect, Viral; Disease Models, Animal; Drug Evaluation, Preclinical; HIV Infections; Leukocytes, Mononuclear; Organophosphonates; Sheep; Visna; Visna-maedi virus | 1995 |
Long-term therapy for herpes retinitis in an animal model with high-concentrated liposome-encapsulated HPMPC.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Electroretinography; Eye Infections, Viral; Fundus Oculi; Herpes Simplex; Liposomes; Longitudinal Studies; Organophosphonates; Organophosphorus Compounds; Rabbits; Retinitis | 1995 |
HPMPC, a broad-spectrum topical antiviral agent, inhibits herpes simplex virus type 1 replication and promotes healing of dendritic keratitis in the New Zealand rabbit ocular model.
Topics: Administration, Topical; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cidofovir; Cytosine; Disease Models, Animal; Female; Herpesvirus 1, Human; Keratitis, Dendritic; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine; Vero Cells; Virus Replication | 1994 |
Model of acute graft-vs-host-disease in adult (SHR x BN.lx)F1 rats and its inhibition by adenine analog.
Topics: Adenine; Animals; Bone Marrow Transplantation; Disease Models, Animal; Female; Graft vs Host Disease; Hybridization, Genetic; Immunosuppressive Agents; Male; Organophosphonates; Rats; Rats, Inbred BN; Rats, Inbred SHR; Transplantation, Homologous | 1993 |
Prevention of acute graft-versus-host disease in rats using 9-(2-phosphonomethoxyethyl) adenine (PMEA).
Topics: Acute Disease; Adenine; Animals; Disease Models, Animal; Female; Graft vs Host Disease; Immunosuppressive Agents; Immunotherapy; Injections, Intraperitoneal; Organophosphonates; Rats; Rats, Inbred BN; Rats, Inbred SHR | 1993 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for the treatment of lethal vaccinia virus infections in severe combined immune deficiency (SCID) mice.
Topics: Animals; Antiviral Agents; Brain; Cidofovir; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Kidney; Liver; Lung; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Vaccinia; Vaccinia virus; Virus Replication | 1993 |
Rat cytomegalovirus-induced pneumonitis after allogeneic bone marrow transplantation: effective treatment with (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine.
Topics: Animals; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Immunohistochemistry; Lung; Male; Organophosphonates; Organophosphorus Compounds; Paraffin Embedding; Pneumonia, Viral; Rats; Whole-Body Irradiation | 1993 |
Evaluation of HPMPC therapy for primary and recurrent genital herpes in mice and guinea pigs.
Topics: Acyclovir; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Female; Guinea Pigs; Herpes Genitalis; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Ultraviolet Rays; Vagina; Vaginal Diseases; Virus Replication | 1993 |
Liposome-encapsulated (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for long-acting therapy of viral retinitis.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Drug Carriers; Eye Infections, Viral; Herpes Simplex; Herpesvirus 1, Human; Injections; Liposomes; Organophosphonates; Organophosphorus Compounds; Rabbits; Retina; Retinitis; Vitreous Body | 1996 |
(S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine [(S)-HPMPA]: a purine analogue with trypanocidal activity in vitro and in vivo.
Topics: Acute Disease; Adenine; Animals; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Female; Mice; Mice, Inbred ICR; Organophosphonates; Organophosphorus Compounds; Trypanocidal Agents; Trypanosomiasis | 1996 |
Evaluation of Cidofovir (HPMPC, GS-504) against adenovirus type 5 infection in vitro and in a New Zealand rabbit ocular model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antibodies, Viral; Cidofovir; Cytosine; Disease Models, Animal; Drug Evaluation; Enzyme-Linked Immunosorbent Assay; Eye; Female; Humans; Organophosphonates; Organophosphorus Compounds; Rabbits; Tears; Tumor Cells, Cultured | 1996 |
Systemic administration of an inhibitor of endothelin-converting enzyme for attenuation of cerebral vasospasm following experimental subarachnoid hemorrhage.
Topics: Animals; Disease Models, Animal; Endothelin-1; Endothelins; Ischemic Attack, Transient; Organophosphonates; Protease Inhibitors; Protein Precursors; Rabbits; Subarachnoid Hemorrhage; Tetrazoles; Time Factors | 1996 |
An ocular model of Adenovirus type 5 infection in the rabbit.
Topics: Adenine; Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Eye Diseases; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Replication | 1995 |
Effective treatment of experimental cytomegalovirus-induced encephalo-meningitis in immunocompromised rats with HPMPC.
Topics: Animals; Antiviral Agents; Brain; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; Immune Sera; Immunocompromised Host; Male; Meninges; Meningitis, Viral; Organophosphonates; Organophosphorus Compounds; Rats; Rats, Inbred BN; Time Factors | 1997 |
An animal model for cidofovir (HPMPC) toxicity: intraocular pressure and histopathologic effects.
Topics: Animals; Cidofovir; Ciliary Body; Corneal Diseases; Cytosine; Disease Models, Animal; Eye Diseases; Guinea Pigs; Intraocular Pressure; Iritis; Microscopy, Electron; Organophosphonates; Organophosphorus Compounds; Pigment Epithelium of Eye; Retina; Retinal Diseases; Uveal Diseases | 1997 |
Prevention and reversal of cerebral vasospasm by an endothelin-converting enzyme inhibitor, CGS 26303, in an experimental model of subarachnoid hemorrhage.
Topics: Animals; Disease Models, Animal; Ischemic Attack, Transient; Male; Organophosphonates; Protease Inhibitors; Rabbits; Subarachnoid Hemorrhage; Tetrazoles | 1997 |
Design and synthesis of [2-(8,9-dioxo-2,6-diazabicyclo[5.2.0]non-1(7)-en-2-yl)-ethyl]phosphonic acid (EAA-090), a potent N-methyl-D-aspartate antagonist, via the use of 3-cyclobutene-1,2-dione as an achiral alpha-amino acid bioisostere.
Topics: Animals; Azabicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cyclobutanes; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Ischemic Attack, Transient; Mice; Models, Chemical; N-Methylaspartate; Organophosphonates; Pipecolic Acids; Piperazines; Rats | 1998 |
Trifluridine, cidofovir, and penciclovir in the treatment of experimental herpetic keratitis.
Topics: Acyclovir; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Female; Guanine; Herpesvirus 1, Human; Keratitis, Herpetic; Male; Ointments; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Trifluridine | 1998 |
N-phosphonoalkyl-5-aminomethylquinoxaline-2,3-diones: in vivo active AMPA and NMDA(glycine) antagonists.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids; Animals; Disease Models, Animal; Electroshock; Hydrobromic Acid; Hydrochloric Acid; Hydroxy Acids; Inhibitory Concentration 50; Mice; N-Methylaspartate; Organophosphonates; Quinoxalines | 1999 |
The role of endothelin in mediating virus-induced changes in endothelinB receptor density in mouse airways.
Topics: Animals; Autoradiography; Disease Models, Animal; Down-Regulation; Endothelin-1; Influenza A virus; Lung; Male; Mice; Mice, Inbred CBA; Muscle, Smooth; Neprilysin; Organ Size; Organophosphonates; Orthomyxoviridae Infections; Protease Inhibitors; Receptor, Endothelin B; Receptors, Endothelin; Tetrazoles; Trachea | 1999 |
Effects of a bisphosphonate on bone histomorphometry and dynamics in the canine cruciate deficiency model of osteoarthritis.
Topics: Animals; Anterior Cruciate Ligament; Bone Resorption; Calcification, Physiologic; Cartilage, Articular; Diphosphonates; Disease Models, Animal; Dogs; Knee Joint; Male; Organophosphonates; Osteoarthritis | 1999 |
Autoimmune encephalomyelitis ameliorated by AMPA antagonists.
Topics: Animals; Brain Stem; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Excitatory Amino Acid Antagonists; Guinea Pigs; Motor Neurons; Multiple Sclerosis; Muscle Tonus; Myelin Basic Protein; Neurons; Organophosphonates; Quinoxalines; Rats; Rats, Inbred Lew; Receptors, AMPA; Receptors, Kainic Acid; Recurrence; Spinal Cord; T-Lymphocytes | 2000 |
Acute murine cytomegalovirus infection: a model for determining antiviral activity against CMV induced hepatitis.
Topics: Alanine Transaminase; Animals; Antiviral Agents; Aspartate Aminotransferases; Body Weight; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Female; Ganciclovir; Hepatitis, Viral, Animal; Herpesviridae Infections; Liver; Mice; Mice, Inbred BALB C; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication | 1999 |
Effect of CGS 26303, an endothelin-converting enzyme-neutral endopeptidase inhibitor, on nitrofen-induced congenital diaphragmatic hernia in the rat.
Topics: Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Body Weight; Disease Models, Animal; Endothelin-Converting Enzymes; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Subcutaneous; Linear Models; Liver; Lung; Metalloendopeptidases; Organ Size; Organophosphonates; Phenyl Ethers; Pregnancy; Proportional Hazards Models; Protease Inhibitors; Rats; Reference Values; Survival Analysis; Tetrazoles | 2000 |
Topical effects of cidofovir on cutaneous rabbit warts: treatment regimen and inoculum dependence.
Topics: Administration, Topical; Animals; Antiviral Agents; Cidofovir; Cottontail rabbit papillomavirus; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Organophosphonates; Organophosphorus Compounds; Rabbits; Time Factors; Warts | 2000 |
Lasting effects of transient postinoculation tenofovir [9-R-(2-Phosphonomethoxypropyl)adenine] treatment on SHIV(KU2) infection of rhesus macaques.
Topics: Adenine; Animals; Anti-HIV Agents; CD4 Lymphocyte Count; Cerebrospinal Fluid; Disease Models, Animal; Kinetics; Lymph Nodes; Macaca mulatta; Male; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir; Time Factors; Viral Load | 2000 |
Post-exposure chemoprophylaxis (PECP) against SIV infection of macaques as a model for protection from HIV infection.
Topics: Adenine; Animals; Disease Models, Animal; DNA, Viral; HIV Infections; Humans; Infectious Disease Transmission, Vertical; Macaca fascicularis; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Tenofovir | 2000 |
In vivo anti-papillomavirus activity of nucleoside analogues including cidofovir on CRPV-induced rabbit papillomas.
Topics: Animals; Antiviral Agents; Cidofovir; Cottontail rabbit papillomavirus; Cytosine; Disease Models, Animal; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Papilloma; Papillomavirus Infections; Rabbits; Treatment Outcome; Tumor Virus Infections | 2000 |
Development of virus-specific immune responses in SHIV(KU)-infected macaques treated with PMPA.
Topics: Adenine; Animals; Anti-HIV Agents; Antibodies, Viral; Disease Models, Animal; HIV Antibodies; HIV Infections; HIV-1; Humans; Macaca mulatta; Neutralization Tests; Organophosphonates; Organophosphorus Compounds; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; Tenofovir; Virus Replication | 2001 |
Enhanced cellular immune response and reduced CD8(+) lymphocyte apoptosis in acutely SIV-infected Rhesus macaques after short-term antiretroviral treatment.
Topics: Adenine; Animals; Anti-HIV Agents; Apoptosis; CD8-Positive T-Lymphocytes; Disease Models, Animal; Humans; Immunologic Memory; Macaca mulatta; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Inhibitors; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; T-Lymphocytes, Helper-Inducer; Tenofovir; Viral Load | 2001 |
Diaryl ester prodrugs of FR900098 with improved in vivo antimalarial activity.
Topics: Aldose-Ketose Isomerases; Animals; Antimalarials; Disease Models, Animal; Fosfomycin; Malaria; Mice; Multienzyme Complexes; Organophosphonates; Oxidoreductases; Plasmodium; Prodrugs; Treatment Outcome | 2001 |
Ganciclovir and cidofovir treatment of cytomegalovirus-induced myocarditis in mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Ganciclovir; Herpesviridae Infections; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Muromegalovirus; Myocarditis; Organophosphonates; Organophosphorus Compounds | 2001 |
Treatment of lethal vaccinia virus respiratory infections in mice with cidofovir.
Topics: Administration, Intranasal; Animals; Antiviral Agents; Cidofovir; Cowpox virus; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Injections, Intraperitoneal; Injections, Subcutaneous; Lung; Mice; Mice, Inbred BALB C; Nose; Organ Specificity; Organophosphonates; Organophosphorus Compounds; Paranasal Sinuses; Pneumonia, Viral; Spleen; Vaccinia; Vaccinia virus; Viral Load; Viremia | 2001 |
Reduction of uranium transfer by local chelation in simulated wounds in rats.
Topics: Animals; Bone and Bones; Chelating Agents; Disease Models, Animal; Injections, Intramuscular; Kidney; Male; Organophosphonates; Radiation Injuries; Rats; Rats, Sprague-Dawley; Tissue Distribution; Uranium; Uranium Compounds; Wounds and Injuries | 2001 |
Antiviral efficacy and pharmacokinetics of oral adefovir dipivoxil in chronically woodchuck hepatitis virus-infected woodchucks.
Topics: Adenine; Administration, Oral; Animals; Chemistry, Clinical; Chronic Disease; Disease Models, Animal; DNA, Viral; Hepatitis B; Hepatitis B Virus, Woodchuck; Liver; Marmota; Organophosphonates; Treatment Outcome | 2001 |
Short-term local delivery of an inhibitor of Ras farnesyltransferase prevents neointima formation in vivo after porcine coronary balloon angioplasty.
Topics: Alkyl and Aryl Transferases; Angioplasty, Balloon, Coronary; Animals; Disease Models, Animal; Enzyme Inhibitors; Muscle, Smooth, Vascular; Organophosphonates; Postoperative Complications; Signal Transduction; Swine; Tunica Intima; Vascular Diseases | 2001 |
Predictive efficacy of SCID-hu mouse models for treatment of human cytomegalovirus infections.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Virus Replication | 2001 |
Bioterrorism. Blocking smallpox: a second defense.
Topics: Animals; Antiviral Agents; Bioterrorism; Cidofovir; Cytosine; Disease Models, Animal; Disease Outbreaks; Humans; Macaca fascicularis; Military Medicine; Organophosphonates; Organophosphorus Compounds; Smallpox; Smallpox Vaccine; United States; Variola virus; World Health Organization | 2001 |
Antiviral prophylaxis with twice daily topical cidofovir protects against challenge in the adenovirus type 5/New Zealand rabbit ocular model.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Eye; Female; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Cultivation; Virus Replication | 2001 |
Inhibitory effect of adefovir on viral DNA synthesis and covalently closed circular DNA formation in duck hepatitis B virus-infected hepatocytes in vivo and in vitro.
Topics: Adenine; Animals; Antiviral Agents; Disease Models, Animal; DNA, Circular; DNA, Viral; Ducks; Hepatitis B; Hepatitis B Virus, Duck; Hepatocytes; Organophosphonates | 2002 |
Treatment of lethal cowpox virus respiratory infections in mice with 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine and its orally active diacetate ester prodrug.
Topics: Animals; Antiviral Agents; Area Under Curve; Body Weight; Chlorocebus aethiops; Cidofovir; Cowpox; Cowpox virus; Cytosine; Disease Models, Animal; Female; Lung; Mice; Mice, Inbred BALB C; Nasal Mucosa; Organophosphonates; Organophosphorus Compounds; Prodrugs; Purines; Statistics, Nonparametric; Vero Cells | 2002 |
Characterizing antiviral activity of adefovir dipivoxil in transgenic mice expressing hepatitis B virus.
Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Disease Models, Animal; DNA, Viral; Dose-Response Relationship, Drug; Hepatitis B; Hepatitis B virus; Lamivudine; Liver; Mice; Mice, Transgenic; Organophosphonates; Polymerase Chain Reaction; Reverse Transcriptase Inhibitors; RNA, Viral; Time Factors; Viral Load | 2002 |
The activity of iododeoxyuridine, adenine arabinoside, cytosine arabinoside, ribavirin and phosphonoacetic acid against herpes virus in the hairless mouse model.
Topics: Acetates; Animals; Cytarabine; Disease Models, Animal; Herpes Simplex; Idoxuridine; Kinetics; Mice; Mice, Nude; Organophosphonates; Ribavirin; Ribonucleosides; Simplexvirus; Vidarabine | 1977 |
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine for the treatment of murine cytomegalovirus infection in severe combined immunodeficiency mice.
Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds | 1992 |
Treatment of murine cytomegalovirus infections in severe combined immunodeficient mice with ganciclovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, interferon, and bropirimine.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cidofovir; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Drug Combinations; Ganciclovir; Immunologic Deficiency Syndromes; Interferon Type I; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Organophosphonates; Organophosphorus Compounds; Recombinant Proteins | 1992 |
Pretreatment with topical 0.1% (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine inhibits adenovirus type 5 replication in the New Zealand rabbit ocular model.
Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Colony Count, Microbial; Corneal Diseases; Corneal Stroma; Cytosine; Disease Models, Animal; Eye Infections, Viral; Female; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Premedication; Rabbits; Virus Replication | 1992 |
Efficacy of 9-(2-phosphonylmethoxyethyl)adenine in the therapy of TK+ and TK- herpes simplex virus experimental keratitis.
Topics: Adenine; Administration, Topical; Animals; Antiviral Agents; Bromodeoxyuridine; Disease Models, Animal; Keratitis, Dendritic; Organophosphonates; Rabbits; Simplexvirus | 1991 |
(S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine in the therapy of thymidine kinase-positive and -deficient herpes simplex virus experimental keratitis.
Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytosine; Disease Models, Animal; Drug Administration Schedule; Female; Keratitis, Dendritic; Male; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Rabbits; Random Allocation; Simplexvirus; Thymidine Kinase | 1991 |
[Synthesis and biological activity of aminophenylphosphonic derivatives of levorin].
Topics: Aldehydes; Amines; Animals; Candicidin; Disease Models, Animal; Fungi; In Vitro Techniques; Male; Mice; Mycoses; Organophosphonates; Virus Diseases; Viruses | 1990 |
The effects of disodium ethane-1-hydroxy-1, 1-diphosphonate on adjuvant induced arthritis in rats.
Topics: Animals; Arthritis; Bone Resorption; Calcinosis; Disease Models, Animal; Ethanol; Female; Freund's Adjuvant; Humans; Mycobacterium; Organophosphonates; Ossification, Heterotopic; Radiography; Rats; Rats, Inbred Strains | 1972 |
[Influence of diphosphonate on experimental heparin-osteopathy].
Topics: Animals; Disease Models, Animal; Heparin; Male; Organophosphonates; Osteoporosis; Rats | 1973 |
[Comparative effectiveness of several aminoalkylphosphonic acids in eliminating beryllium from the body of rats].
Topics: Animals; Antidotes; Berylliosis; Disease Models, Animal; Methods; Organophosphonates; Rats | 1972 |
The efficacy of various anthelmintics against the parasitic larval stages of Ancylostoma caninum in Mastomys natalensis.
Topics: Ancylostoma; Animals; Anthelmintics; Benzene Derivatives; Benzimidazoles; Carbamates; Disease Models, Animal; Larva; Muscles; Organophosphonates; Pyridines; Rats; Thiabendazole; Thiazoles; Thiocyanates | 1970 |