Page last updated: 2024-09-05

organophosphonates and Cytomegalovirus

organophosphonates has been researched along with Cytomegalovirus in 150 studies

Research

Studies (150)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (4.67)	18.7374
1990's	54 (36.00)	18.2507
2000's	49 (32.67)	29.6817
2010's	40 (26.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bar-On, S; Haynes, RK; Lantsberg, D; Laskov, I; Oiknine-Djian, E; Panet, A; Wolf, DG	1
Bruminhent, J; Rotjanapan, P; Watcharananan, SP	1
Andrei, G; Buckheit, RW; De Jonghe, S; Groaz, E; Hartman, T; Herdewijn, P; Kalkeri, R; Luo, M; Ptak, RG; Schols, D; Snoeck, R	1
Andrei, G; Balzarini, J; Dračínský, M; Krečmerová, M; Pomeisl, K; Snoeck, R	1
Agrawal, N; Beltran, D; Echenique, IA; Najafian, N; Ramirez-Ruiz, L	1
Grassi, G; Mazzaglia, A; Neri, G; Pennisi, R; Piperno, A; Pizzo, MM; Scala, A; Sciortino, MT; Sortino, G; Zagami, R; Zhu, Y	1
DeVita, AV; Gentry, BG; Markovich, KC; O'Brien, MS; Selleseth, D; Sethna, P	1
Boeckh, MJ; Brundage, TM; Chemaly, RF; Chittick, G; Foster, SA; Marty, FM; Morrison, ME; Mullane, KM; Nichols, WG; Papanicolaou, GA; Shore, TB; Wilson, C; Winston, DJ	1
Hartline, CB; James, SH; Lanier, ER; Price, NB; Prichard, MN	1
Boeckh, M; Brundage, TM; Godkin, S; Marty, FM; Momméja-Marin, H; Mullane, KM; Papanicolaou, GA; Robertson, AT; Rowley, SD; Vance, E; Winston, DJ	1
Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Laib Sampaio, K	1
Bowlin, TL; Chou, S; Komazin-Meredith, G; Williams, JD	1
Boivin, G; Piret, J	1
Gregg, K; Hakki, M; Kaul, DR	1
Peggs, KS; Sellar, RS	1
Chou, S; Ercolani, RJ; Lefterova, MI; Pinsky, BA; Sahoo, MK; Strasfeld, LM	1
Florescu, DF; Keck, MA	1
Griffiths, P; Lumley, S	1
Boeckh, M; Murphy, WJ; Peggs, KS	1
Andrei, G; Kokosza, K; Piotrowska, DG; Schols, D; Snoeck, R	1
Fischer, L; Göhring, K; Hamprecht, K; Jahn, G; Sampaio, KL	1
Alain, S; Andouard, D; Cahen, R; Couvreux, A; Deering, M; Hantz, S; Ligat, G; Mazeron, MC; Pouteil-Noble, C; Viget, N; Yasdanpanah, Y	1
Chou, S; Ercolani, RJ; Lanier, ER	1
Fischer, L; Göhring, K; Hamprecht, K; Hofmann, J; Imrich, E; Jahn, G; Sampaio, KL	1
Gerna, G; Lilleri, D	1
Abbo, LM; Alencar, MC; Camargo, JF; Komanduri, KV; Lekakis, LJ; Morris, MI; Saneeymehri, S; Simkins, J	1
Ariza-Heredia, EJ; Chemaly, RF; El Chaer, F; El-Haddad, D; Gulbis, AM; Mulanovich, VE; Shah, DP; Shpall, EJ; Vanichanan, J	1
Brundage, T; Chittick, G; Morrison, M; Nichols, WG	1
Krecmerova, M	1
Andrei, G; Chen, X; Liu, NN; Schols, D; Snoeck, R; Wen, YN; Wu, QP; Xiang, YH; Zhang, QS; Zhang, ZF; Zhang, ZY	1
Asano-Mori, Y; Chiba, S; Kako, S; Kanda, Y; Kurokawa, M; Motokura, T; Oshima, K; Shiraki, K; Watanabe, T	1
Járay, J; Péter, A; Telkes, G; Varga, M	1
Drach, JC; Ksebati, B; Mhaske, SB; Prichard, MN; Zemlicka, J	1
Chou, S; Lurain, NS	1
Kern, ER; Prichard, MN	1
Andrei, G; Balzarini, J; Dračínský, M; Holý, A; Krečmerová, M; Snoeck, R; Tichý, T	1
Borysko, K; Breitenbach, J; Drach, JC; Hilfinger, J; Kashemirov, BA; Kijek, P; Kim, JS; McKenna, CE; Mitchell, S; Peterson, LW	1
Borysko, KZ; Breitenbach, JM; Collins, M; Drach, JC; Hilfinger, JM; Kashemirov, BA; Krylov, IS; McKenna, CE; Peterson, LW; Serpi, M; Zakharova, VM	1
Bowlin, TL; Chou, S; Marousek, G	1
Hong, JH; Kim, E; Li, H; Yoo, JC	1
Chavala, S; Miller, MB; Moss, HB; Say, E	1
Carmichael, A; Goldsmith, PM; Husain, MM; Middleton, SJ; Zhang, H	1
Ang, BC; Teoh, SC	1
Aldern, KA; Beadle, JR; Harden, E; Hartline, C; Hostetler, KY; Kern, ER; Rodriguez, N	1
Zaia, JA	2
Bakker, HI; De Boer, FM; Harmsen, MC; Meijer, DK; Molema, G; van der Strate, BW	1
Baldanti, F; Campanini, G; Comolli, G; Gerna, G; Lilleri, D; Ridolfo, AL; Rusconi, S	1
Alain, S; Belloc, S; Brouet, JC; Ducancelle, A; Malphettes, M; Mazeron, MC; Petit, F; Sanson Le Pors, MJ; Scieux, C	1
Clark, DA; Emery, VC; Fryer, JF; Griffiths, PD	1
Baldanti, F; Gerna, G; Lurain, N	1
Bidanset, DJ; Hartline, CB; Kern, ER; Rybak, RJ	2
Beadle, JR; Bidanset, DJ; Hostetler, KY; Kern, ER; Wan, WB	1
Beadle, JR; Collins, DJ; Hostetler, KY; Kern, ER; Quenelle, DC; Wan, WB	1
Freitag, M; Herget, T; Kupfer, R; Marschall, M; Morbitzer, M; Stamminger, T	1
Beadle, JR; Ciesla, SL; Hartline, C; Hostetler, KY; Kern, ER; Valiaeva, N; Wan, WB	1
Morton, CJ; Ng, HL; Parker, MW; Rawlinson, WD; Scott, GM	1
Beadle, JR; Daily, SL; Harden, EA; Hartline, CB; Hostetler, KY; Kern, ER; Kushner, NL; Prichard, MN; Wan, WB; Williams-Aziz, SL	1
Hong, JH; Kim, A	1
Boivin, G; Gilbert, C	1
De Clercq, E	2
Beadle, JR; Ciesla, SL; Hartline, C; Hostetler, KY; Keith, KA; Kern, ER; Wan, WB	1
Hong, JH; Hyun Oh, C	1
Chou, S; Drew, WL; Marousek, GI; Miner, RC	1
Aldern, KA; Beadle, JR; Hartline, CB; Hostetler, KY; Kern, ER; Ruiz, JC	1
Chou, S; Rawlinson, WD; Scott, GM; Weinberg, A	1
Hong, JH; Kim, A; Oh, CH	1
Abdelhalim, A; Almyroudis, NG; Battiwalla, M; Becker, J; Elefante, A; McCarthy, A; McCarthy, PL; Paplham, P; Segal, BH; Smith, P	1
Eizuru, Y	1
Bernstein, DI; Bravo, FJ; Cardin, RD	1
Chou, S; Marousek, GI	1
Beadle, JR; Collins, DJ; Hartline, CB; Hostetler, KY; Kern, ER; Pettway, LR; Quenelle, DC; Wan, WB	1
Chou, S; Li, S; Marousek, G; Weinberg, A	1
Chatterjee, S; Gangopadhyay, NN; Whitley, RJ	1
Hamzeh, FM; Lee, FE; Lietman, PS; Moore, MR	1
De Clercq, E; Neyts, J	1
Barnard, DL; Huffman, JH; Reist, EJ; Sidwell, RW	1
Bruggeman, CA; de Clercq, E; Havenith, M; Stals, FS; Zeytinoglu, A	1
De Clercq, E; Neyts, J; Snoeck, R; Sobis, H; Vandeputte, M	1
Cherrington, JM; Drew, WL; Hitchcock, MJ; Lalezari, JP; Miner, R	1
Chen, MS; Huang, ES; Kim, C; Smith, JL; Xiong, X	1
Flaherty, JF	1
Andrei, G; Balzarini, J; De Clercq, E; Dvoráková, H; Holý, A; Masojídková, M; Snoeck, R	1
Bryson, HM; Lea, AP	1
Andrei, G; De Clercq, E; Snoeck, R	1
Bosmans, E; Bron, D; De Clereq, E; Delforge, A; Lagneaux, L; Schols, D; Snoeck, R; Stryckmans, P	1
Chen, MS; Smith, JL; Xiong, X	1
Kuppermann, BD	1
Eizuru, Y; Harada, K; Ihara, S; Isashiki, Y; Minamishima, Y	1
Cherrington, JM; Freeman, WR; Fuller, MD; Jiles, RE; Smith, IL; Spector, SA	1
Chou, S; Drew, WL; Follansbee, SE; Guentzel, S; Lalezari, JP; Marousek, G; Miner, RC; Poscher, ME	1
Pérez, JL	1
Cherrington, JM; Collier, A; Deeks, SG; Drew, WL; Hellmann, N; Jaffe, HS; Kahn, J; Lalezari, J; Lamy, PD; Li, W; Mulato, AS; Pavia, A; Rodrigue, D; Toole, J	1
Chen, MS; Cherrington, JM; Flores, C; Fuller, MD; Mendel, DB; Moon, K; Mulato, AS; Xiong, X	1
Takahashi, K	1
Ai, E; Freeman, WR; Mueller, AJ; Powell, HC; Rahhal, FM; Smith, IL; Spector, SA; Taskintuna, I	1
Baldanti, F; Biron, KK; Gerna, G	1
De Clercq, E; Efimtseva, EV; Fomicheva, MV; Khomutov, AR; Meshkov, SV; Mikhaĭlov, SN; Rodionov, MS	1
Freeman, WR; Karavellas, MP; Macdonald, JC; Morse, LS; Reed, JB; Torriani, FJ	1
Cherrington, JM; Cihlar, T; Fuller, MD	1
Cherrington, JM; Cihlar, T; Fuller, MD; Mulato, AS	1
Aissa, N; Carquin, J; Dewilde, A; Freymuth, F; Houhou-Fidouh, N; Mazeron, MC; Scieux, C; Thouvenot, D	1
Dunn, JP; Enger, C; Forman, M; Hubbard, L; Jabs, DA	1
Cherrington, JM; Drew, WL; Fuller, MD; Lalezari, JP; Lamy, PD; Miner, R; Nuessle, S	1
Avila, CP; Cheng, L; Freeman, WR; Keefe, KS; Macdonald, JC; Rao, NA	1
Bedard, J; Bowlin, T; Chan, L; Drach, J; Huffman, J; Lis, M; May, S; Rando, R; Sidwell, R; Tryphonas, L	1
Barbeau, D; Bedard, J; Bowlin, TL; May, S; Rando, RF; Yuen, L	1
Buchanan, J; Davis, LJ	1
Bowen, EF; Cherrington, JM; Emery, VC; Griffiths, PD; Johnson, MA; Lamy, PD	1
Cherrington, J; Jaffe, HS; Safrin, S	1
Botsis, C; Kyriakis, KP; Paparizos, VA; Papastamopoulos, V; Stavrianeas, NG; Zagoraios, Y	1
Einsele, H; Hebart, H	1
Biel, SS; Chen, S; Gelderblom, HR; Held, TK; Kurth, A; Nitsche, A; Siegert, W	1
Chou, S; Drew, WL; Miner, RC	1
Distler, A; Ketteler, M; Mertz, A; Offermann, G; Preuschof, L; Schäfer, H; Stöffler-Meilicke, M	1
Boeckh, M; Chuang, EL; Corey, L; Crippa, F; Sale, G	1
Bruggeman, CA; Bruning, JH; De Clercq, E; Lemström, K; Persoons, M; Stals, FS	1
Bandt, D; Bornhäuser, M; Ehninger, G; Freiberg-Richter, J; Geissler, G; Helwig, A; Platzbecker, U; Plettig, R; Rethwilm, A; Schuler, U; Thiede, C	1
Blanchet, KD	1
Emery, VC	1
Basara, N; Kiehl, MG	1
Castagnola, E; Chierici, M; Cristina, E; Lanino, E; Miano, M; Morreale, G	1
Alkan, S; Bhorade, SM; Garrity, ER; Husain, AN; McCabe, MA; Norwick, L; Sandesara, C; Vigneswaran, WT; Yeldandi, V	1
Chakrabarti, S; Collingham, KE; Fegan, CD; Milligan, DW; Osman, H	1
Chou, SW	1
Bartolozzi, B; Bosi, A; Guidi, S; Orsi, A; Rossi Ferrini, P; Vannucchi, AM	1
Andrei, G; Blaheta, RA; Cinatl, J; De Clercq, E; Doerr, HW; Kreuter, J; Michaelis, M; Neyts, J; Rabenau, HF; Snoeck, R; Vogel, JU	1
Cinatl, J; Doerr, HW; Kreuter, J; Langer, K; Michaelis, M; Rabenau, H; Vogel, JU	1
Huang, ES	1
Miller, RL; Rapp, F	1
Stinski, MF	1
Hitchcock, MJ; Mansuri, MM; Martin, JC; Starrett, JE; Tortolani, DR	1
Holý, A; Otová, B; Votruba, I	1
Kern, ER	1
Hitchcock, MJ; Martin, JC	1
Andrei, G; De Clercq, E; Neyts, J; Schols, D; Snoeck, R	1
Balzarini, J; De Clercq, E; Neyts, J; Snoeck, R	1
De Clercq, E; Himpens, B; Neyts, J; Schols, D; Snoeck, R	1
Bruggeman, CA; de Clercq, E; Stals, FS	1
Baba, M; De Clercq, E; Konno, K; Shigeta, S; Yokota, T	1
Kim, CU; Luh, BY; Martin, JC	1
Feng, JS; Fong, CK; Hsiung, GD; Li, SB; Lucia, HL; Yang, ZH	1
Balzarini, J; Bron, D; De Clercq, E; Delforge, A; Lagneaux, L; Snoeck, R; Stryckmans, P; Van der Auwera, P	1
Balzarini, J; De Clercq, E; Neyts, J; Schols, D; Snoeck, R	1
Bronson, JJ; Ghazzouli, I; Hitchcock, MJ; Martin, JC; Webb, RR	1
De Clercq, E; Holy, A; Rosenberg, I; Sakuma, T; Snoeck, R	1
Barker, MF; Duke, AE; Martin, JC; Matthews, TR; McGee, DP; Prisbe, EJ; Smee, DF; Verheyden, JP	1

Reviews

22 review(s) available for organophosphonates and Cytomegalovirus

Article	Year
Antiviral drug resistance in herpesviruses other than cytomegalovirus. Reviews in medical virology, 2014, Volume: 24, Issue:3 Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Herpesvirus 6, Human; Humans; Immunocompromised Host; Organophosphonates	2014
Therapeutic strategies for cytomegalovirus infection in haematopoietic transplant recipients: a focused update. Expert opinion on biological therapy, 2014, Volume: 14, Issue:8 Topics: Acetates; Antiviral Agents; Benzimidazoles; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy, Adoptive; Organophosphonates; Quinazolines; Ribonucleosides; T-Lymphocytes; Transplant Recipients; Transplantation, Homologous	2014
Cytomegalovirus. Current opinion in infectious diseases, 2014, Volume: 27, Issue:6 Topics: Acetates; Antiviral Agents; Benzimidazoles; Bone Marrow Transplantation; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Transmission, Infectious; Double-Blind Method; Female; Ganciclovir; Humans; Male; Organ Transplantation; Organophosphonates; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; Quinazolines; Randomized Controlled Trials as Topic; Ribonucleosides	2014
Recent advances in cytomegalovirus: an update on pharmacologic and cellular therapies. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2015, Volume: 21, Issue:1 Topics: Acetates; Adoptive Transfer; Animals; Antiviral Agents; Benzimidazoles; Cell- and Tissue-Based Therapy; Clinical Trials, Phase III as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Isoxazoles; Killer Cells, Natural; Leflunomide; Mice; Organophosphonates; Quinazolines; Ribonucleosides; T-Lymphocytes	2015
Strategies to control human cytomegalovirus infection in adult hematopoietic stem cell transplant recipients. Immunotherapy, 2016, Volume: 8, Issue:9 Topics: Acetates; Adult; Animals; Antiviral Agents; Asymptomatic Diseases; Benzimidazoles; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Management; Gastroenteritis; Hematopoietic Stem Cell Transplantation; Humans; Immunotherapy; Monitoring, Immunologic; Organophosphonates; Pneumonia; Postoperative Complications; Quinazolines; Ribonucleosides	2016
Amino Acid Ester Prodrugs of Nucleoside and Nucleotide Antivirals. Mini reviews in medicinal chemistry, 2017, Volume: 17, Issue:10 Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; Humans; Nucleosides; Nucleotides; Organophosphonates; Prodrugs	2017
[Gastrointestinal cytomegalovirus infections in organ transplant patients]. Orvosi hetilap, 2008, Dec-21, Volume: 149, Issue:52 Topics: Acyclovir; Antiviral Agents; Biopsy; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Endoscopy, Gastrointestinal; Foscarnet; Ganciclovir; Gastric Mucosa; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Immunocompromised Host; Immunoglobulins; Immunotherapy, Adoptive; Intestinal Mucosa; Organ Transplantation; Organophosphonates; Primary Prevention; Valganciclovir	2008
Antiviral drug resistance of human cytomegalovirus. Clinical microbiology reviews, 2010, Volume: 23, Issue:4 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genome, Viral; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Sequence Analysis, DNA	2010
The search for new therapies for human cytomegalovirus infections. Virus research, 2011, Volume: 157, Issue:2 Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Guanine; Humans; Organophosphonates; Valganciclovir; Virus Replication	2011
Prevention and management of CMV-related problems after hematopoietic stem cell transplantation. Bone marrow transplantation, 2002, Volume: 29, Issue:8 Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Risk Factors	2002
Clinical and biologic aspects of human cytomegalovirus resistance to antiviral drugs. Human immunology, 2004, Volume: 65, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Antiretroviral Therapy, Highly Active; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Mutational Analysis; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Virus Replication	2004
The acyclic nucleoside phosphonates from inception to clinical use: historical perspective. Antiviral research, 2007, Volume: 75, Issue:1 Topics: Antiviral Agents; Cytomegalovirus; Hepatitis B virus; History, 20th Century; History, 21st Century; HIV-1; Humans; Nucleosides; Organophosphonates	2007
[Mechanism of drug-resistance in human cytomegalovirus]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Feb-28, Volume: 65 Suppl 2 Pt. 1 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins	2007
Cidofovir. Drugs, 1996, Volume: 52, Issue:2 Topics: Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds	1996
Therapeutic options for resistant cytomegalovirus retinitis. Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Volume: 14 Suppl 1 Topics: AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Infusions, Intravenous; Organophosphonates; Organophosphorus Compounds; Recurrence; Thionucleotides	1997
Resistance to antivirals in human cytomegalovirus: mechanisms and clinical significance. Microbiologia (Madrid, Spain), 1997, Volume: 13, Issue:3 Topics: Antiviral Agents; Cidofovir; Codon; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins; Viral Structural Proteins	1997
[Recent advances in antiviral drugs--antiviral agents to HCMV, HHV-6, and HHV-7]. Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:1 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Purines; Thymidine Kinase	1998
Cidofovir. Review of current and potential clinical uses. Advances in experimental medicine and biology, 1999, Volume: 458 Topics: AIDS-Related Opportunistic Infections; Animals; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds	1999
Cytomegalovirus infection following stem cell transplantation. Haematologica, 1999, Volume: 84 Suppl EHA-4 Topics: Acyclovir; Antibodies, Viral; Antiviral Agents; Blood Donors; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunocompromised Host; Immunotherapy, Adoptive; Leukocyte Transfusion; Organophosphonates; Organophosphorus Compounds; Premedication; Risk Factors; Tissue Donors; Transfusion Reaction; Virus Latency	1999
Progress in understanding cytomegalovirus drug resistance. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2001, Volume: 21, Issue:3 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Forecasting; Foscarnet; Ganciclovir; Humans; Incidence; Organophosphonates; Organophosphorus Compounds	2001
Cytomegalovirus drug resistance and clinical implications. Transplant infectious disease : an official journal of the Transplantation Society, 2001, Volume: 3 Suppl 2 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Incidence; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Risk Factors	2001
Value of animal models to evaluate agents with potential activity against human cytomegalovirus. Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3 Topics: Acyclovir; Animals; Antiviral Agents; Cell Division; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Fibroblasts; Ganciclovir; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Virus Replication	1991

Trials

6 trial(s) available for organophosphonates and Cytomegalovirus

Article	Year
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial of Oral Brincidofovir for Cytomegalovirus Prophylaxis in Allogeneic Hematopoietic Cell Transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2019, Volume: 25, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Aged; Allografts; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organophosphonates; Survival Rate	2019
CMX001 to prevent cytomegalovirus disease in hematopoietic-cell transplantation. The New England journal of medicine, 2013, Sep-26, Volume: 369, Issue:13 Topics: Administration, Oral; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Diarrhea; DNA, Viral; Dose-Response Relationship, Drug; Double-Blind Method; Female; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Organophosphonates; Polymerase Chain Reaction; Transplantation, Homologous	2013
Short-term clinical safety profile of brincidofovir: A favorable benefit-risk proposition in the treatment of smallpox. Antiviral research, 2017, Volume: 143 Topics: Adenoviridae; Adolescent; Adult; Animals; Antiviral Agents; Cytomegalovirus; Cytosine; Disease Models, Animal; Double-Blind Method; Drug Administration Schedule; Humans; Middle Aged; Organophosphonates; Orthopoxvirus; Safety; Smallpox; Young Adult	2017
Susceptibility of human cytomegalovirus to cidofovir is unchanged after limited in vivo exposure to various regimens of drug. The Journal of infectious diseases, 1996, Volume: 173, Issue:4 Topics: Adult; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds	1996
The safety and efficacy of adefovir dipivoxil, a novel anti-human immunodeficiency virus (HIV) therapy, in HIV-infected adults: a randomized, double-blind, placebo-controlled trial. The Journal of infectious diseases, 1997, Volume: 176, Issue:6 Topics: Adenine; Administration, Oral; Adult; Anti-HIV Agents; Carnitine; CD4 Lymphocyte Count; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Lymphocyte Count; Male; Middle Aged; Mutation; Organophosphonates; Polymerase Chain Reaction; RNA, Viral; Semen; Sequence Analysis, RNA; T-Lymphocyte Subsets	1997
Cidofovir for cytomegalovirus-preemptive therapy in stem cell transplant recipients. Blood, 2001, Sep-01, Volume: 98, Issue:5 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Myelodysplastic Syndromes; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Transplantation, Homologous; Treatment Failure; Viremia; Virus Activation	2001

Other Studies

122 other study(ies) available for organophosphonates and Cytomegalovirus

Article	Year
Artemisone demonstrates synergistic antiviral activity in combination with approved and experimental drugs active against human cytomegalovirus. Antiviral research, 2019, Volume: 172 Topics: Acetates; Antiviral Agents; Artemisinins; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Interactions; Drug Synergism; Drugs, Investigational; Female; Ganciclovir; Humans; Organ Culture Techniques; Organophosphonates; Placenta; Pregnancy; Quinazolines; Ribonucleosides	2019
Epidemiology and Outcome of Ganciclovir-Resistant Cytomegalovirus Infection After Solid Organ Transplantation: A Single Transplant Center Experience in Thailand. Transplantation proceedings, 2017, Volume: 49, Issue:5 Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Liver Transplantation; Male; Middle Aged; Mutation; Organ Transplantation; Organophosphonates; Postoperative Complications; Real-Time Polymerase Chain Reaction; Retrospective Studies; Thailand; Young Adult	2017
Expanding the Antiviral Spectrum of 3-Fluoro-2-(phosphonomethoxy)propyl Acyclic Nucleoside Phosphonates: Diamyl Aspartate Amidate Prodrugs. Journal of medicinal chemistry, 2017, 07-27, Volume: 60, Issue:14 Topics: Adenine; Anti-HIV Agents; Antiviral Agents; Aspartic Acid; Cell Line; Cytomegalovirus; Drug Resistance, Viral; Drug Stability; Esters; Hepatitis B virus; Herpesvirus 3, Human; Humans; Hydrogen-Ion Concentration; Microsomes, Liver; Nucleosides; Organophosphonates; Prodrugs; Stereoisomerism; Structure-Activity Relationship	2017
New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity. Bioorganic & medicinal chemistry, 2017, 09-01, Volume: 25, Issue:17 Topics: Antiviral Agents; Cell Line; Cytomegalovirus; Herpesvirus 3, Human; Humans; Organophosphonates; Prodrugs; Pyrimidine Nucleosides; Simplexvirus	2017
Ganciclovir Dosing Strategies and Development of Cytomegalovirus Resistance in a Kidney Transplant Recipient: A Case Report. Transplantation proceedings, 2017, Volume: 49, Issue:7 Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Immunoglobulins; Immunoglobulins, Intravenous; Isoxazoles; Kidney; Kidney Transplantation; Leflunomide; Male; Organophosphonates; Postoperative Complications; Tissue Donors	2017
Intracellular trafficking and therapeutic outcome of multiwalled carbon nanotubes modified with cyclodextrins and polyethylenimine. Colloids and surfaces. B, Biointerfaces, 2018, Mar-01, Volume: 163 Topics: Animals; Antiviral Agents; beta-Cyclodextrins; Biological Transport; Chlorocebus aethiops; Cidofovir; Cytomegalovirus; Cytosine; Drug Carriers; Drug Liberation; Green Fluorescent Proteins; Kinetics; Lysosomes; Nanotubes, Carbon; Organophosphonates; Plasmids; Polyethyleneimine; Rhodamines; Vero Cells	2018
In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus. Antiviral research, 2018, Volume: 158 Topics: Antiviral Agents; Benzimidazoles; Cell Line; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Antagonism; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Endodeoxyribonucleases; Fibroblasts; Foscarnet; Ganciclovir; Guanine; Humans; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Ribonucleosides; Viral Proteins; Virus Replication	2018
Selection and recombinant phenotyping of a novel CMX001 and cidofovir resistance mutation in human cytomegalovirus. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Amino Acid Sequence; Antiviral Agents; Base Sequence; Cells, Cultured; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Sequence Analysis, DNA	2013
Generation and characterization of a GCV resistant HCMV UL97-mutation and a drug sensitive UL54-mutation. Antiviral research, 2013, Volume: 100, Issue:3 Topics: Antiviral Agents; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutagenesis; Mutation, Missense; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins	2013
Cytomegalovirus mutants resistant to ganciclovir and cidofovir differ in susceptibilities to synguanol and its 6-ether and 6-thioether derivatives. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3 Topics: Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytosine; Drug Resistance, Multiple, Viral; Foscarnet; Ganciclovir; Genotype; Guanine; Mutation; Organophosphonates	2014
UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease. Transplant infectious disease : an official journal of the Transplantation Society, 2014, Volume: 16, Issue:2 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Mutation; Organophosphonates; Viral Proteins	2014
Improved detection of emerging drug-resistant mutant cytomegalovirus subpopulations by deep sequencing. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; High-Throughput Nucleotide Sequencing; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Organophosphonates; Pneumonia, Viral; Time Factors; Viral Proteins; Virus Replication	2014
Development of CMX001 (Brincidofovir) for the treatment of serious diseases or conditions caused by dsDNA viruses. Expert review of anti-infective therapy, 2014, Volume: 12, Issue:10 Topics: Adenoviridae; Antiviral Agents; Cytomegalovirus; Cytosine; DNA Virus Infections; Humans; Microbial Sensitivity Tests; Molluscum contagiosum virus; Organophosphonates; Orthopoxvirus; Polyomavirus	2014
Design, antiviral and cytostatic properties of isoxazolidine-containing amonafide analogues. Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13 Topics: Acrylamides; Adenine; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Cell Survival; Cycloaddition Reaction; Cytomegalovirus; Cytostatic Agents; Drug Design; Enterovirus; Humans; Isoxazoles; Naphthalimides; Nitrogen Oxides; Organophosphonates; Phlebovirus; Simplexvirus; Structure-Activity Relationship; Vaccinia virus	2015
Identification of newly detected, drug-related HCMV UL97- and UL54-mutations using a modified plaque reduction assay. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 69 Topics: Adult; Antiviral Agents; Cell Line; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Multiple, Viral; Female; Ganciclovir; Genotype; Humans; Infant; Male; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins	2015
Contrasting effect of new HCMV pUL54 mutations on antiviral drug susceptibility: Benefits and limits of 3D analysis. Antiviral research, 2016, Volume: 129 Topics: Antiviral Agents; Chromosomes, Artificial, Bacterial; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Models, Molecular; Mutagenesis; Organophosphonates; Phenotype; Point Mutation; Protein Domains; Viral Proteins	2016
Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Gene Expression; Humans; Microbial Sensitivity Tests; Mutation; Organophosphonates; Protein Domains; Viral Proteins	2016
Identification of resistance-associated HCMV UL97- and UL54-mutations and a UL97-polymporphism with impact on phenotypic drug-resistance. Antiviral research, 2016, Volume: 131 Topics: Adolescent; Adult; Antiviral Agents; Child; Chromosomes, Artificial, Bacterial; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Infant; Middle Aged; Mutation; Organophosphonates; Phenotype; Phosphotransferases (Alcohol Group Acceptor); Polymorphism, Genetic; Viral Proteins	2016
The use of brincidofovir for the treatment of mixed dsDNA viral infection. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2016, Volume: 83 Topics: Adult; Antiviral Agents; BK Virus; Coinfection; Cytomegalovirus; Cytosine; DNA Virus Infections; Fatal Outcome; Female; Herpesvirus 4, Human; Humans; Immunocompromised Host; Organophosphonates; Stem Cell Transplantation; Viral Load; Young Adult	2016
Brincidofovir (CMX-001) for refractory and resistant CMV and HSV infections in immunocompromised cancer patients: A single-center experience. Antiviral research, 2016, Volume: 134 Topics: Aged; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Viral; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Herpesviridae Infections; Humans; Immunocompromised Host; Male; Middle Aged; Neoplasms; Organophosphonates	2016
Synthesis and Ativiral Activity of 5-(Benzylthio)-4-carbamyl-1,2,3-triazoles Against Human Cytomegalovirus (CMV) and Varicella-zoster Virus (VZV). Medicinal chemistry (Shariqah (United Arab Emirates)), 2017, Volume: 13, Issue:5 Topics: Acyclovir; Antiviral Agents; Bromodeoxyuridine; Cidofovir; Cytomegalovirus; Cytosine; Ganciclovir; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; Organophosphonates; Thymidine Kinase; Triazoles	2017
Case report: persistent cytomegalovirus (CMV) infection after haploidentical hematopoietic stem cell transplantation using in vivo alemtuzumab: emergence of resistant CMV due to mutations in the UL97 and UL54 genes. Journal of medical virology, 2008, Volume: 80, Issue:10 Topics: Alemtuzumab; Anemia, Refractory, with Excess of Blasts; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antiviral Agents; Base Sequence; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Sequence Data; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Viral Proteins; Virus Activation	2008
Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity. Bioorganic & medicinal chemistry, 2009, Jun-01, Volume: 17, Issue:11 Topics: Animals; Antiviral Agents; Cyclopropanes; Cytomegalovirus; Guanine; Humans; Inhibitory Concentration 50; Isomerism; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Organophosphonates; Simplexvirus	2009
New prodrugs of Adefovir and Cidofovir. Bioorganic & medicinal chemistry, 2011, Jun-01, Volume: 19, Issue:11 Topics: Adenine; Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytomegalovirus; Cytosine; Herpesvirus 3, Human; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus	2011
Synthesis, transport and antiviral activity of Ala-Ser and Val-Ser prodrugs of cidofovir. Bioorganic & medicinal chemistry letters, 2011, Jul-01, Volume: 21, Issue:13 Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine	2011
Tyrosine-based 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine and -adenine ((S)-HPMPC and (S)-HPMPA) prodrugs: synthesis, stability, antiviral activity, and in vivo transport studies. Journal of medicinal chemistry, 2011, Aug-25, Volume: 54, Issue:16 Topics: Adenine; Animals; Antiviral Agents; Area Under Curve; Biological Availability; Cell Line, Tumor; Cell Survival; Cells, Cultured; Cidofovir; Cowpox virus; Cytomegalovirus; Cytosine; Fibroblasts; Herpesvirus 1, Human; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Molecular Structure; Organophosphonates; Prodrugs; Rats; Tyrosine; Vaccinia virus	2011
Cyclopropavir susceptibility of cytomegalovirus DNA polymerase mutants selected after antiviral drug exposure. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:1 Topics: Alkaline Phosphatase; Antiviral Agents; Cidofovir; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exonucleases; Foscarnet; Ganciclovir; Genes, Reporter; Genotype; Guanine; Humans; Inhibitory Concentration 50; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication	2012
Synthesis of novel difluoro-cyclopropyl guanine nucleosides and their phosphonate analogues as potent antiviral agents. Nucleosides, nucleotides & nucleic acids, 2011, Volume: 30, Issue:11 Topics: Antiviral Agents; Cell Line; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Infections; Guanine; Halogenation; HIV Infections; HIV-1; Humans; Nucleosides; Organophosphonates	2011
Ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with wild-type CMV in her plasma. Journal of clinical microbiology, 2012, Volume: 50, Issue:5 Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Viral; Eye; Female; Foscarnet; Ganciclovir; Humans; Organophosphonates; Plasma; Sequence Analysis, DNA	2012
Case report: Multidrug-resistant cytomegalovirus in a modified multivisceral transplant recipient. Transplantation, 2012, Apr-15, Volume: 93, Issue:7 Topics: Adult; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Multiple, Viral; Female; Foscarnet; Ganciclovir; Humans; Immunosuppressive Agents; Intestine, Small; Isoxazoles; Kidney Transplantation; Leflunomide; Organophosphonates; Pancreas Transplantation; Recurrence; Stomach; Treatment Outcome	2012
Case report of cytomegalovirus retinitis in an HIV-positive patient with a CD4-count nadir of 254 cells per μl. Eye (London, England), 2012, Volume: 26, Issue:8 Topics: Adenine; Administration, Oral; Adult; Alkynes; Anti-HIV Agents; Aqueous Humor; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cyclopropanes; Cytomegalovirus; Cytomegalovirus Retinitis; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV Infections; Humans; Male; Organophosphonates; Polymerase Chain Reaction; Tenofovir; Visual Acuity	2012
Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:8 Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Fibroblasts; Guinea Pigs; Herpesvirus 1, Human; Herpesvirus 2, Human; Humans; Liposomes; Mice; Organophosphonates; Organophosphorus Compounds; Rats; Structure-Activity Relationship; Viral Plaque Assay; Virus Replication	2002
Prevention of cytomegalovirus disease in hematopoietic stem cell transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Oct-15, Volume: 35, Issue:8 Topics: Acyclovir; Antiviral Agents; Chemoprevention; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Transplantation, Autologous; Transplantation, Homologous; Valacyclovir; Valganciclovir; Valine	2002
Synergy of bovine lactoferrin with the anti-cytomegalovirus drug cidofovir in vitro. Antiviral research, 2003, Volume: 58, Issue:2 Topics: Acyclovir; Animals; Antiviral Agents; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Synergism; Foscarnet; Ganciclovir; Inhibitory Concentration 50; Lactoferrin; Organophosphonates; Organophosphorus Compounds	2003
Human cytomegalovirus double resistance in a donor-positive/recipient-negative lung transplant patient with an impaired CD4-mediated specific immune response. The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:3 Topics: Antigens, Viral; Antiviral Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cidofovir; Cytokines; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Immunity, Cellular; Lung; Lung Transplantation; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds	2004
Comparison of sequential cytomegalovirus isolates in a patient with lymphoma and failing antiviral therapy. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2004, Volume: 29, Issue:4 Topics: Aged; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Viral; Evolution, Molecular; Female; Foscarnet; Ganciclovir; Humans; Lymphoma, T-Cell; Molecular Epidemiology; Mutation, Missense; Organophosphonates; Organophosphorus Compounds; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA	2004
Susceptibility of porcine cytomegalovirus to antiviral drugs. The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:6 Topics: Animals; Antiviral Agents; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA, Viral; Fluorescent Antibody Technique, Indirect; Foscarnet; Ganciclovir; Organophosphonates; Organophosphorus Compounds; Reverse Transcriptase Polymerase Chain Reaction; Swine; Virus Replication	2004
Efficacy of ganciclovir and cidofovir against human cytomegalovirus replication in SCID mice implanted with human retinal tissue. Antiviral research, 2004, Volume: 63, Issue:1 Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Transplantation, Heterologous; Virus Replication	2004
Oral activity of ether lipid ester prodrugs of cidofovir against experimental human cytomegalovirus infection. The Journal of infectious diseases, 2004, Aug-01, Volume: 190, Issue:3 Topics: Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Esters; Ether; Humans; Lipids; Male; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Prodrugs; Treatment Outcome	2004
Oral treatment of murine cytomegalovirus infections with ether lipid esters of cidofovir. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:9 Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esters; Female; Injections, Intraperitoneal; Injections, Intravenous; Lipids; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Structure-Activity Relationship; Viral Load	2004
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity. Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:11 Topics: Antiviral Agents; Blotting, Western; Cell Line; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Viral; Enzyme Inhibitors; Ganciclovir; Humans; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Plasmids; Quinazolines; Viral Plaque Assay; Virus Replication	2004
Comparison of the antiviral activities of alkoxyalkyl and alkyl esters of cidofovir against human and murine cytomegalovirus replication in vitro. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:2 Topics: Animals; Anti-HIV Agents; Cells, Cultured; Cidofovir; Coloring Agents; Cytomegalovirus; Cytosine; Esters; Ethylene Glycols; Glycerol; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Neutral Red; Organophosphonates; Propylene Glycols; Structure-Activity Relationship; Viral Plaque Assay; Virus Replication	2005
Murine cytomegalovirus resistant to antivirals has genetic correlates with human cytomegalovirus. The Journal of general virology, 2005, Volume: 86, Issue:Pt 8 Topics: Acyclovir; Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Ganciclovir; Guanine; Humans; Mice; Models, Molecular; Molecular Sequence Data; Muromegalovirus; Mutation; Organophosphonates; Protein Kinases; Sequence Alignment; Valacyclovir; Valine; Virus Replication	2005
Comparative activities of lipid esters of cidofovir and cyclic cidofovir against replication of herpesviruses in vitro. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:9 Topics: Antiviral Agents; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Cidofovir; Cyclization; Cytomegalovirus; Cytosine; Enzyme-Linked Immunosorbent Assay; Esters; Fibroblasts; Flow Cytometry; Herpesviridae; Humans; In Situ Hybridization; Organophosphonates; Structure-Activity Relationship; Tetrazolium Salts; Thiazoles; Viral Plaque Assay; Virus Replication	2005
Synthesis and antiviral evaluation of novel exomethylene acyclic nucleosides and phosphonic acid nucleosides. Archiv der Pharmazie, 2005, Volume: 338, Issue:11 Topics: Antiviral Agents; Cell Line; Cell Survival; Cytomegalovirus; Humans; Methane; Molecular Structure; Nucleosides; Organophosphonates; Structure-Activity Relationship	2005
New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure. Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:12 Topics: Amino Acid Sequence; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA, Viral; Drug Resistance, Viral; Ganciclovir; Humans; Molecular Sequence Data; Mutation; Organophosphonates	2005
Inhibition of the replication of DNA viruses by phosphonylmethoxyalkyl-purines and -pyrimidines. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Viruses; Organophosphonates; Simplexvirus; Virus Replication	1989
Synthesis and antiviral evaluation of alkoxyalkyl derivatives of 9-(S)-(3-hydroxy-2-phosphonomethoxypropyl)adenine against cytomegalovirus and orthopoxviruses. Journal of medicinal chemistry, 2006, Mar-23, Volume: 49, Issue:6 Topics: Adenine; Antiviral Agents; Cell Line; Cytomegalovirus; Esters; Humans; Organophosphonates; Orthopoxvirus; Stereoisomerism; Structure-Activity Relationship	2006
Synthesis and antiviral evaluation of novel cyclopropyl nucleosides, phosphonate nucleosides and phosphonic acid nucleosides. Archiv der Pharmazie, 2006, Volume: 339, Issue:9 Topics: Antiviral Agents; Cell Line; Cyclopropanes; Cytomegalovirus; Humans; Microbial Sensitivity Tests; Molecular Structure; Nucleosides; Organophosphonates	2006
Maribavir sensitivity of cytomegalovirus isolates resistant to ganciclovir, cidofovir or foscarnet. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, Volume: 37, Issue:2 Topics: Antiviral Agents; Benzimidazoles; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Ribonucleosides; Viral Proteins	2006
Synthesis and antiviral evaluation of alkoxyalkyl esters of phosphonopropoxymethyl-guanine and phosphonopropoxymethyl-diaminopurine. Antiviral chemistry & chemotherapy, 2006, Volume: 17, Issue:2 Topics: 2-Aminopurine; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Guanine; Herpesvirus 1, Human; Humans; Magnetic Resonance Spectroscopy; Organophosphonates; Spectrometry, Mass, Electrospray Ionization; Viral Plaque Assay	2006
Multidrug resistance conferred by novel DNA polymerase mutations in human cytomegalovirus isolates. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Drug Resistance, Multiple; Drug Resistance, Viral; Foscarnet; Ganciclovir; Genotype; Humans; Immunocompromised Host; Mutation; Organophosphonates; Phenotype; Viral Proteins; Virus Replication	2007
Synthesis and anti-HCMV activity of novel cyclopropyl phosphonic acid nucleosides. Nucleosides, nucleotides & nucleic acids, 2006, Volume: 25, Issue:12 Topics: Anti-HIV Agents; Antiviral Agents; Cytomegalovirus; Hydrolysis; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleosides; Organophosphonates; Phosphoric Acids; Phosphorous Acids; Pyrimidine Nucleosides	2006
Leflunomide failure to control recurrent cytomegalovirus infection in the setting of renal failure after allogeneic stem cell transplantation. Transplant infectious disease : an official journal of the Transplantation Society, 2007, Volume: 9, Issue:1 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Therapy, Combination; Encephalitis, Viral; Fatal Outcome; Ganciclovir; Hodgkin Disease; Humans; Isoxazoles; Leflunomide; Male; Middle Aged; Organophosphonates; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Renal Insufficiency; Secondary Prevention; Treatment Failure; Virus Activation	2007
A model of human cytomegalovirus infection in severe combined immunodeficient mice. Antiviral research, 2007, Volume: 76, Issue:2 Topics: Animals; Antiviral Agents; Cell Culture Techniques; Cell Line; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Gelatin Sponge, Absorbable; Humans; Male; Mice; Mice, SCID; Organophosphonates; Viral Plaque Assay	2007
Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant. Journal of virology, 2008, Volume: 82, Issue:1 Topics: Amino Acid Sequence; Amino Acid Substitution; Antiviral Agents; Benzimidazoles; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Foscarnet; Ganciclovir; Humans; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Organophosphonates; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Ribonucleosides; Sequence Alignment; Viral Proteins	2008
Effect of oral treatment with (S)-HPMPA, HDP-(S)-HPMPA or ODE-(S)-HPMPA on replication of murine cytomegalovirus (MCMV) or human cytomegalovirus (HCMV) in animal models. Antiviral research, 2008, Volume: 79, Issue:2 Topics: Adenine; Administration, Oral; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Herpesviridae Infections; Liver; Mice; Mice, Inbred BALB C; Mice, SCID; Muromegalovirus; Organophosphonates; Survival Analysis	2008
Contrasting drug resistance phenotypes resulting from cytomegalovirus DNA polymerase mutations at the same exonuclease locus. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2008, Volume: 43, Issue:1 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Viral; Exodeoxyribonucleases; Foscarnet; Ganciclovir; Humans; Mutation; Organophosphonates; Phenotype; Protein Structure, Tertiary; Viral Proteins	2008
A rapid protein A binding radioimmunoassay for the evaluation of antiviral agents. Journal of virological methods, 1994, Volume: 48, Issue:2-3 Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Evaluation Studies as Topic; Ganciclovir; Humans; Interferons; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Radioimmunoassay; Staphylococcal Protein A; Time Factors; Virus Replication	1994
Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl) cytosine against human cytomegalovirus when administered as single-bolus dose and continuous infusion in in vitro cell culture perfusion system. Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:10 Topics: Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Half-Life; Humans; Organophosphonates; Organophosphorus Compounds	1994
New inhibitors of cytomegalovirus replication: in vitro evaluation, mechanism of action, and in vivo activity. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie, 1994, Volume: 56, Issue:6 Topics: Adenine; Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Ganciclovir; Herpesviridae Infections; Humans; Immunologic Deficiency Syndromes; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Virus Replication	1994
Selective inhibition of cytomegaloviruses by 9-(3'-ethylphosphono-1'-hydroxymethyl-1'-propyloxy-methyl)g uanine. Antiviral research, 1993, Volume: 22, Issue:1 Topics: Animals; Antiviral Agents; Cells, Cultured; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Fibroblasts; Ganciclovir; Guinea Pigs; Humans; Mice; Mice, Inbred BALB C; Muromegalovirus; Organophosphonates; Stereoisomerism; Time Factors; Viral Plaque Assay	1993
Rat cytomegalovirus-induced pneumonitis after allogeneic bone marrow transplantation: effective treatment with (S)-1-(3-hydroxy-2-phosphonyl-methoxypropyl)cytosine. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:2 Topics: Animals; Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Immunohistochemistry; Lung; Male; Organophosphonates; Organophosphorus Compounds; Paraffin Embedding; Pneumonia, Viral; Rats; Whole-Body Irradiation	1993
Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)-cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)-guanine in the treatment of intracerebral murine cytomegalovirus infections in immunocompetent and immunodeficient mice. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1993, Volume: 12, Issue:4 Topics: Animals; Animals, Newborn; Antiviral Agents; Brain; Brain Diseases; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Ganciclovir; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds	1993
Kinetic analysis of the interaction of cidofovir diphosphate with human cytomegalovirus DNA polymerase. Biochemical pharmacology, 1996, Jun-14, Volume: 51, Issue:11 Topics: Animals; Antiviral Agents; Base Sequence; Cattle; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA; Fibroblasts; Humans; Kinetics; Molecular Sequence Data; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Viral Proteins	1996
Current and experimental therapeutic options for cytomegalovirus disease. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1996, Apr-15, Volume: 53, Issue:8 Suppl 2 Topics: Administration, Oral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Delayed-Action Preparations; Foscarnet; Ganciclovir; Guanine; Humans; Injections, Intravenous; Organophosphonates; Organophosphorus Compounds	1996
Synthesis of 2'-aminomethyl derivatives of N-(2-(phosphonomethoxy)ethyl) nucleotide analogues as potential antiviral agents. Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17 Topics: 3T3 Cells; Animals; Antiviral Agents; Cell Line; Cytomegalovirus; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 3, Human; HIV-1; HIV-2; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Molecular Structure; Moloney murine sarcoma virus; Organophosphonates; Purine Nucleotides; Pyrimidine Nucleotides; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship; Vaccinia virus	1996
Patterns of resistance and sensitivity to antiviral compounds of drug-resistant strains of human cytomegalovirus selected in vitro. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:7 Topics: Acyclovir; Adenine; Antiviral Agents; Cells, Cultured; Cidofovir; Cytarabine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Fibroblasts; Foscarnet; Humans; Lung; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid	1996
Imbalance in production of cytokines by bone marrow stromal cells following cytomegalovirus infection. The Journal of infectious diseases, 1996, Volume: 174, Issue:5 Topics: Bone Marrow Cells; Cidofovir; Cytokines; Cytomegalovirus; Cytosine; Ganciclovir; Humans; Lipopolysaccharides; Organophosphonates; Organophosphorus Compounds; Stromal Cells; Virus Replication	1996
Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:3 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Primers; DNA-Directed DNA Polymerase; DNA, Viral; Humans; Organophosphonates; Organophosphorus Compounds; Templates, Genetic	1997
Genetic analysis of a clinical isolate of human cytomegalovirus exhibiting resistance against both ganciclovir and cidofovir. Archives of virology, 1997, Volume: 142, Issue:2 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Sequence Analysis, DNA	1997
High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes. The Journal of infectious diseases, 1997, Volume: 176, Issue:1 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance; Ganciclovir; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor)	1997
Evolution of mutations conferring multidrug resistance during prophylaxis and therapy for cytomegalovirus disease. The Journal of infectious diseases, 1997, Volume: 176, Issue:3 Topics: Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Male; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Recombination, Genetic; RNA-Directed DNA Polymerase; Sequence Analysis, DNA	1997
In vitro characterization of the anti-human cytomegalovirus activity of PMEA (Adefovir). Antiviral research, 1997, Volume: 36, Issue:2 Topics: Adenine; Antiviral Agents; Cell Line; Cytomegalovirus; HeLa Cells; Humans; Organophosphonates	1997
Clinical failure of CMV retinitis with intravitreal cidofovir is associated with antiviral resistance. Archives of ophthalmology (Chicago, Ill. : 1960), 1998, Volume: 116, Issue:2 Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA, Viral; Drug Resistance, Microbial; Ganciclovir; Humans; Injections; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Treatment Failure; Vitreous Body	1998
Interpreting human cytomegalovirus antiviral drug susceptibility testing: the role of mixed virus populations. The Journal of infectious diseases, 1998, Volume: 177, Issue:3 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds	1998
[Acyclic nucleotide analogues based on phosphonic acids]. Bioorganicheskaia khimiia, 1998, Volume: 24, Issue:1 Topics: Amides; Animals; Antiviral Agents; Cells, Cultured; Chlorocebus aethiops; Cytomegalovirus; HeLa Cells; Herpesvirus 3, Human; Humans; Magnetic Resonance Spectroscopy; Nucleotides; Organophosphonates; Oximes; Stereoisomerism; Structure-Activity Relationship; Vero Cells	1998
Lack of reactivation of cytomegalovirus (CMV) retinitis after stopping CMV maintenance therapy in AIDS patients with sustained elevations in CD4 T cells in response to highly active antiretroviral therapy. The Journal of infectious diseases, 1998, Volume: 177, Issue:5 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiviral Agents; CD4 Lymphocyte Count; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Therapy, Combination; Female; HIV Protease Inhibitors; HIV-1; Humans; Male; Organophosphonates; Organophosphorus Compounds; Recurrence; Virus Activation; Virus Replication	1998
Characterization of drug resistance-associated mutations in the human cytomegalovirus DNA polymerase gene by using recombinant mutant viruses generated from overlapping DNA fragments. Journal of virology, 1998, Volume: 72, Issue:7 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genes, Viral; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Recombination, Genetic; Virus Replication	1998
A point mutation in the human cytomegalovirus DNA polymerase gene selected in vitro by cidofovir confers a slow replication phenotype in cell culture. Virology, 1998, Sep-01, Volume: 248, Issue:2 Topics: Amino Acid Sequence; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; DNA, Viral; Drug Resistance, Microbial; Enzyme Repression; Exonucleases; Ganciclovir; Molecular Sequence Data; Organophosphonates; Organophosphorus Compounds; Phenotype; Phosphodiesterase I; Phosphoric Diester Hydrolases; Point Mutation; Sequence Homology, Amino Acid; Viral Proteins; Virus Replication	1998
[Comparison of the in vitro sensitivity to cidofovir and ganciclovir of clinical cytomegalovirus isolates. Coordinated Action Group 11]. Pathologie-biologie, 1998, Volume: 46, Issue:6 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Synthesis Inhibitors; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Viral Proteins	1998
Cytomegalovirus retinitis and viral resistance: 3. Culture results. CMV Retinitis and Viral Resistance Study Group. American journal of ophthalmology, 1998, Volume: 126, Issue:4 Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Baltimore; Blood; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Female; Follow-Up Studies; Foscarnet; Ganciclovir; Humans; Male; Organophosphonates; Organophosphorus Compounds; Prognosis; Prospective Studies; Survival Rate; Urine; Viremia	1998
In vitro antiviral susceptibilities of isolates from cytomegalovirus retinitis patients receiving first- or second-line cidofovir therapy: relationship to clinical outcome. The Journal of infectious diseases, 1998, Volume: 178, Issue:6 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Resistance, Microbial; Foscarnet; Ganciclovir; Genotype; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Recurrence	1998
Cytomegalovirus iritis. Ophthalmic surgery and lasers, 1998, Volume: 29, Issue:11 Topics: Adult; AIDS-Related Opportunistic Infections; Antibodies, Viral; Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytomegalovirus Retinitis; Cytosine; Fatal Outcome; Humans; Immunohistochemistry; Iris; Iritis; Male; Organophosphonates; Organophosphorus Compounds	1998
Comparative study of the anti-human cytomegalovirus activities and toxicities of a tetrahydrofuran phosphonate analogue of guanosine and cidofovir. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:3 Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Guanosine; Guinea Pigs; Humans; Kidney; Male; Mice; Mice, Inbred BALB C; Organophosphonates; Organophosphorus Compounds; Phosphinic Acids; Rats; Viral Plaque Assay; Virus Replication	1999
A high throughput colorimetric cell proliferation assay for the identification of human cytomegalovirus inhibitors. Antiviral research, 1999, Volume: 41, Issue:1 Topics: Antiviral Agents; Cidofovir; Colorimetry; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Fibroblasts; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Tetrazolium Salts; Virus Replication	1999
Comment: cidofovir in the treatment of cytomegaloviral disease. The Annals of pharmacotherapy, 1999, Volume: 33, Issue:6 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Organophosphonates; Organophosphorus Compounds	1999
Quantitative changes in cytomegalovirus DNAemia and genetic analysis of the UL97 and UL54 genes in AIDS patients receiving cidofovir following ganciclovir therapy. Journal of medical virology, 1999, Volume: 58, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA-Directed DNA Polymerase; DNA, Viral; Ganciclovir; Genotype; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases (Alcohol Group Acceptor); Prospective Studies; Retinitis; Viral Load; Viral Proteins	1999
Adefovir dipivoxil. Bis-POM PMEA, GS 0840, GS 840, Piv2PMEA. Drugs in R&D, 1999, Volume: 2, Issue:5 Topics: Adenine; Animals; Anti-HIV Agents; Biological Availability; Cytomegalovirus; Cytomegalovirus Infections; Double-Blind Method; Drugs, Investigational; HIV Infections; Humans; Macaca fascicularis; Male; Organophosphonates; Protein Binding; Randomized Controlled Trials as Topic; Semen	1999
Lack of reactivation of cytomegalovirus retinitis in an AIDS patient, during and after stopping long-term cidofovir treatment: case report. Journal of chemotherapy (Florence, Italy), 2000, Volume: 12, Issue:3 Topics: Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Administration Schedule; Humans; Male; Organophosphonates; Organophosphorus Compounds; Virus Activation	2000
Treatment of BK virus-associated hemorrhagic cystitis and simultaneous CMV reactivation with cidofovir. Bone marrow transplantation, 2000, Volume: 26, Issue:3 Topics: Antiviral Agents; BK Virus; Cidofovir; Cystitis; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Hematuria; Humans; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomavirus Infections; Virus Activation	2000
A deletion mutation in region V of the cytomegalovirus DNA polymerase sequence confers multidrug resistance. The Journal of infectious diseases, 2000, Volume: 182, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; DNA-Directed DNA Polymerase; Drug Resistance, Microbial; Drug Resistance, Multiple; Foscarnet; Ganciclovir; Gene Deletion; Humans; Mutation; Organophosphonates; Organophosphorus Compounds; Phosphotransferases; Transfection	2000
Fatal cytomegalovirus pneumonia after preemptive antiviral therapy in a renal transplant recipient. Clinical nephrology, 2000, Volume: 54, Issue:5 Topics: Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Fatal Outcome; Female; Foscarnet; Ganciclovir; Humans; Kidney Transplantation; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pneumonia, Viral; Polymerase Chain Reaction; Postoperative Complications	2000
Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2001, Jan-15, Volume: 32, Issue:2 Topics: Adult; Antiviral Agents; Chronic Disease; Cidofovir; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Female; Foscarnet; Ganciclovir; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Risk Factors; Treatment Outcome; Virus Activation	2001
Enhancement of transplantation-associated atherosclerosis by CMV, which can be prevented by antiviral therapy in the form of HPMPC. Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7 Suppl 1 Topics: Animals; Antiviral Agents; Aorta; Arteriosclerosis; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Graft Rejection; Male; Organophosphonates; Organophosphorus Compounds; Postoperative Complications; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous; Transplantation, Isogeneic; Tunica Intima; Tunica Media; Virus Replication	1994
Successful preemptive cidofovir treatment for CMV antigenemia after dose-reduced conditioning and allogeneic blood stem cell transplantation. Transplantation, 2001, Apr-15, Volume: 71, Issue:7 Topics: Adult; Antigens, Viral; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Feasibility Studies; Female; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Male; Middle Aged; Mycoses; Myeloablative Agonists; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Preventive Medicine; Prospective Studies; Transplantation Conditioning; Viral Matrix Proteins	2001
CMV retinitis: a clinical management update. AIDS patient care and STDs, 1996, Volume: 10, Issue:2 Topics: AIDS-Related Opportunistic Infections; Algorithms; Antiviral Agents; Cidofovir; Clinical Protocols; Clinical Trials as Topic; Cytomegalovirus; Cytomegalovirus Retinitis; Cytosine; Drug Implants; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Injections; Organophosphonates; Organophosphorus Compounds; Patient Participation; Vitreous Body	1996
Strategies for management of cytomegalovirus (CMV) infection after allogeneic bone marrow transplantation: the "doubling of baseline CMV pp65 antigenemia" and the "cidofovir as rescue treatment approaches. Blood, 2001, Sep-01, Volume: 98, Issue:5 Topics: Antigens, Viral; Antiviral Agents; Bone Marrow Transplantation; Child; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Drug Resistance, Microbial; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Phosphoproteins; Recurrence; Salvage Therapy; Time Factors; Transplantation, Homologous; Viral Matrix Proteins; Viremia	2001
Quantification of cytomegalovirus (CMV) viral load by the hybrid capture assay allows for early detection of CMV disease in lung transplant recipients. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2001, Volume: 20, Issue:9 Topics: Adult; Antiviral Agents; Cell Culture Techniques; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Female; Ganciclovir; Humans; Illinois; Immunization, Passive; Lung Transplantation; Male; Middle Aged; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Predictive Value of Tests; Prospective Studies; Reagent Kits, Diagnostic; Sensitivity and Specificity; Survival Analysis; Syndrome; Viral Load	2001
Predictive efficacy of SCID-hu mouse models for treatment of human cytomegalovirus infections. Antiviral chemistry & chemotherapy, 2001, Volume: 12 Suppl 1 Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Mice; Mice, SCID; Organophosphonates; Organophosphorus Compounds; Virus Replication	2001
Cidofovir as primary pre-emptive therapy for post-transplant cytomegalovirus infections. Bone marrow transplantation, 2001, Volume: 28, Issue:9 Topics: Adult; Antiviral Agents; Cidofovir; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Drug Evaluation; Eye Infections, Viral; Female; Foscarnet; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Organophosphorus Compounds; Pilot Projects; Polymerase Chain Reaction; Probenecid; Recurrence; Safety; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Uveitis, Anterior; Viral Load; Viremia; Vomiting	2001
Polymerase chain reaction-based "pre-emptive" therapy with cidofovir for cytomegalovirus reactivation in allogeneic hematopoietic stem cells transplantation recipients: a prospective study. Haematologica, 2002, Volume: 87, Issue:4 Topics: Adult; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; DNA, Viral; Hematopoietic Stem Cell Transplantation; Humans; Middle Aged; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Prospective Studies; Virus Activation	2002
Antiviral and immunomodulatory activity of the metal chelator ethylenediaminedisuccinic acid against cytomegalovirus in vitro and in vivo. Antiviral research, 2002, Volume: 55, Issue:1 Topics: Adjuvants, Immunologic; Animals; Antiviral Agents; Cell Adhesion; Cell Line; Chelating Agents; Cidofovir; Cytomegalovirus; Cytosine; Drug Resistance, Microbial; Ethylenediamines; Herpesviridae Infections; Humans; Intercellular Adhesion Molecule-1; Jurkat Cells; Mice; Mice, SCID; Muromegalovirus; Organophosphonates; Organophosphorus Compounds; Succinates; Virus Replication	2002
In vitro antiviral activity of aphidicolin and its derivates. Synergistic effects of aphidicolin with other antiviral drugs. Arzneimittel-Forschung, 2002, Volume: 52, Issue:5 Topics: Adenoviridae; Antiviral Agents; Aphidicolin; Cidofovir; Cytomegalovirus; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Herpesvirus 1, Human; Humans; Indicators and Reagents; Organophosphonates; Organophosphorus Compounds; Virus Replication	2002
Human cytomegalovirus. IV. Specific inhibition of virus-induced DNA polymerase activity and viral DNA replication by phosphonoacetic acid. Journal of virology, 1975, Volume: 16, Issue:6 Topics: Acetates; Antiviral Agents; Cell Line; Cytomegalovirus; Depression, Chemical; DNA; DNA Nucleotidyltransferases; DNA Replication; DNA, Viral; Humans; Organophosphonates; Organophosphorus Compounds; Templates, Genetic	1975
Distinguishing cytomegalovirus, mycoplasma, and cellular DNA polymerases. Journal of virology, 1976, Volume: 20, Issue:3 Topics: Acetates; Ammonium Sulfate; Cell Line; Cytomegalovirus; DNA-Directed DNA Polymerase; Ethylmaleimide; Hydroxymercuribenzoates; Mycoplasma; Organophosphonates; Organophosphorus Compounds	1976
Synthesis of proteins and glycoproteins in cells infected with human cytomegalovirus. Journal of virology, 1977, Volume: 23, Issue:3 Topics: Antigens, Viral; Culture Techniques; Cytomegalovirus; DNA, Viral; Glycoproteins; Humans; Inclusion Bodies, Viral; Molecular Weight; Organophosphonates; Peptide Biosynthesis; Protein Biosynthesis; Viral Proteins; Virus Replication	1977
Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine. Antiviral research, 1992, Volume: 19, Issue:3 Topics: Adenine; Antiviral Agents; Cell Line; Cytomegalovirus; Drug Evaluation, Preclinical; HIV; Humans; Organophosphonates; Prodrugs; Simplexvirus	1992
Pretreatment of the host cell with 1-(S)-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) is sufficient for its antiviral effect. Acta virologica, 1992, Volume: 36, Issue:3 Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytopathogenic Effect, Viral; Cytosine; Drug Administration Schedule; Humans; In Vitro Techniques; Organophosphonates; Organophosphorus Compounds; Virus Replication	1992
Phosphonomethylether compounds as antiviral agents. Transplantation proceedings, 1991, Volume: 23, Issue:3 Suppl 3 Topics: Animals; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Haplorhini; Herpes Simplex; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Structure-Activity Relationship	1991
Antiviral activity of anti-cytomegalovirus agents (HPMPC, HPMPA) assessed by a flow cytometric method and DNA hybridization technique. Antiviral research, 1991, Volume: 16, Issue:1 Topics: Adenine; Antiviral Agents; Cell Line; Cidofovir; Cytomegalovirus; Cytosine; Flow Cytometry; Ganciclovir; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay	1991
Particular characteristics of the anti-human cytomegalovirus activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) in vitro. Antiviral research, 1991, Volume: 16, Issue:1 Topics: Animals; Antiviral Agents; Cidofovir; Cytarabine; Cytidine; Cytomegalovirus; Cytosine; Deoxycytidine; DNA, Viral; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Virus Replication	1991
Sensitive, reproducible and convenient fluorometric assay for the in vitro evaluation of anti-cytomegalovirus agents. Journal of virological methods, 1991, Volume: 35, Issue:1 Topics: Acyclovir; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Esterases; Flow Cytometry; Fluoresceins; Fluorometry; Foscarnet; Ganciclovir; Humans; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Polyethylene Glycols; Suramin	1991
Comparative activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine and 9-(1,3-dihydroxy-2-propoxymethyl)guanine against rat cytomegalovirus infection in vitro and in vivo. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:11 Topics: Animals; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Guanosine Triphosphate; Humans; Male; Organophosphonates; Organophosphorus Compounds; Rats; Viral Plaque Assay; Virus Replication	1991
Comparative inhibitory effects of nucleoside analogues on different clinical isolates of human cytomegalovirus in vitro. The Journal of infectious diseases, 1991, Volume: 163, Issue:2 Topics: Adenine; Adenosine; Antiviral Agents; Cell Line; Cidofovir; Cytidine; Cytomegalovirus; Cytosine; Ganciclovir; Guanosine; Humans; Nucleosides; Organophosphonates; Organophosphorus Compounds; Thymidine	1991
Synthesis and antiviral activity of (S)-9-[4-hydroxy-3-(phosphonomethoxy)butyl]guanine. Journal of medicinal chemistry, 1990, Volume: 33, Issue:6 Topics: Adenine; Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Guanine; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Viral Plaque Assay	1990
Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) against guinea pig cytomegalovirus infection in cultured cells and in guinea pigs. Antiviral research, 1990, Volume: 13, Issue:5 Topics: Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytomegalovirus Infections; Cytosine; Dose-Response Relationship, Drug; Guinea Pigs; Organ Specificity; Organophosphonates; Organophosphorus Compounds; Viral Plaque Assay; Virus Replication	1990
Inhibitory effects of potent inhibitors of human immunodeficiency virus and cytomegalovirus on the growth of human granulocyte-macrophage progenitor cells in vitro. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1990, Volume: 9, Issue:8 Topics: Adenine; Adult; Antiviral Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Foscarnet; Ganciclovir; Granulocytes; Hematopoietic Stem Cells; HIV; Humans; Macrophages; Organophosphonates; Organophosphorus Compounds; Phosphonoacetic Acid; Zidovudine	1990
Selective inhibition of human cytomegalovirus DNA synthesis by (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine [(S)-HPMPC] and 9-(1,3-dihydroxy-2-propoxymethyl)guanine (DHPG). Virology, 1990, Volume: 179, Issue:1 Topics: Antiviral Agents; Cell Line; Cell Survival; Cidofovir; Cytomegalovirus; Cytosine; DNA; DNA Replication; DNA, Viral; Flow Cytometry; Ganciclovir; Humans; Organophosphonates; Organophosphorus Compounds	1990
Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine. Journal of medicinal chemistry, 1989, Volume: 32, Issue:7 Topics: Animals; Antiviral Agents; Chemical Phenomena; Chemistry; Cidofovir; Cytomegalovirus; Cytosine; Cytosine Nucleotides; Female; Guinea Pigs; Humans; Mice; Organophosphonates; Organophosphorus Compounds; Simplexvirus; Vero Cells	1989
(S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine, a potent and selective inhibitor of human cytomegalovirus replication. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:12 Topics: Antiviral Agents; Cidofovir; Cytomegalovirus; Cytosine; Humans; Organophosphonates; Organophosphorus Compounds; Virus Replication	1988
Synthesis and antiherpes virus activity of phosphate and phosphonate derivatives of 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine. Journal of medicinal chemistry, 1986, Volume: 29, Issue:5 Topics: Acyclovir; Administration, Oral; Animals; Cell Line; Cytomegalovirus; Female; Ganciclovir; Haplorhini; Humans; In Vitro Techniques; Injections, Subcutaneous; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Organophosphonates; Phosphates; Simplexvirus; Thymidine Kinase	1986