Compounds > organophosphonates
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organophosphonates and Cancer of Cervix

organophosphonates has been researched along with Cancer of Cervix in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (18.18)18.2507
2000's7 (31.82)29.6817
2010's11 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aktaş, Y; Bilensoy, E; Sandler, N; Varan, C; Wickström, H1
Deberne, M; Dessen, P; Deutsch, E; Levy, A; Mondini, M; Supiramaniam, A; Vivet, S; Vozenin, MC1
Andrei, G; De Schutter, T; Duraffour, S; Matthys, P; Mitera, T; Snoeck, R; Topalis, D; van den Oord, J1
Andrei, G; Balzarini, J; De Schutter, T; El Amri, C; Krečmerová, M; Naesens, L; Nogueira, TC; Snoeck, R; Topalis, D1
Adam, J; Bayar, MA; Chargari, C; Deutsch, E; Haie-Meder, C; Lanoy, E; Laporte, M; Levy, A; Magné, N; Mazeron, R; Mondini, M; Pautier, P; Soria, JC; Varga, A; Vassal, G1
Andrei, G; Mertens, B; Naesens, L; Nogueira, T; Snoeck, R; Stranska, R1
Battistelli, S; Benedetti, S; Catalani, S; Galati, R; Nuvoli, B; Palma, F1
Donne, AJ; Hampson, IN; Hampson, L; He, XT; Homer, JJ; Rothera, MP1
Bossens, M; Bucella, D; Gilles, C; Larsimont, D; Manigart, Y; Reynders, M; Rozenberg, S; Snoeck, R; Van Pachterbeke, C; Vanden Houte, K1
Aldern, KA; Beadle, JR; Hostetler, KY; Trahan, J; Valiaeva, N1
Chen, W; Dou, Y; Gao, Z; Guo, J; Li, Y; Liu, A; Wang, H; Yan, Z; Yang, Y; Zhao, X1
Andersson, Y; Fodstad, O; Guldvik, IJ; Hergenrother, PJ; Ju, J; Palchaudhuri, R; Risberg, K; Xi, Y1
Andrei, G; De Schutter, T; Duraffour, S; Matthys, P; Mitera, T; Naesens, L; Snoeck, R; Topalis, D; van den Oord, J1
Aldern, KA; Beadle, JR; Corbeil, J; Hostetler, KY; Rought, S; Trahan, J1
Snoeck, R1
Abdulkarim, B; Amine, A; Aubel, C; Bourhis, J; Violot, D; Vozenin-Brotons, MC1
Asbury, RF; Blessing, JA; Soper, JT1
Asbury, R; Blessing, JA; Buller, R; Look, KY; Lucci, JA1
Andrei, G; De Clercq, E; Delvenne, P; Piette, J; Snoeck, R1
Bossens, M; De Clercq, E; Muller, C; Noel, JC; Snoeck, R1
Abdulkarim, B; Bourhis, J; Chagraoui, H; Chouaïb, S; Deutsch, E; Eschwege, F; Maggiorella, L; Sabri, S; Thierry, J; Vainchenker, W1
Alberts, DS; Craig, JB; Hannigan, EV; Liu, PY; Malviya, VK; Surwit, EA1

Reviews

1 review(s) available for organophosphonates and Cancer of Cervix

ArticleYear
Papillomavirus and treatment.
    Antiviral research, 2006, Volume: 71, Issue:2-3

    Topics: Antiviral Agents; Carcinoma; Chemotherapy, Adjuvant; Cidofovir; Cytosine; Female; Humans; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Uterine Cervical Neoplasms; Viral Vaccines; Warts

2006

Trials

6 trial(s) available for organophosphonates and Cancer of Cervix

ArticleYear
Phase I trial evaluating the antiviral agent Cidofovir in combination with chemoradiation in cervical cancer patients.
    Oncotarget, 2016, May-03, Volume: 7, Issue:18

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brachytherapy; Carboplatin; Chemoradiotherapy; Cidofovir; Cytosine; Female; Humans; Middle Aged; Organophosphonates; Radiation-Sensitizing Agents; Uterine Cervical Neoplasms

2016
Topical treatment of CIN 2+ by cidofovir: results of a phase II, double-blind, prospective, placebo-controlled study.
    Gynecologic oncology, 2009, Volume: 115, Issue:1

    Topics: Administration, Topical; Adult; Antineoplastic Agents; Cidofovir; Combined Modality Therapy; Conization; Contraceptive Devices, Female; Cytosine; Double-Blind Method; Female; Gels; Humans; Organophosphonates; Papillomavirus Infections; Placebos; Prospective Studies; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2009
A Gynecologic Oncology Group phase II study of amonafide (NSC #308847) in squamous cell carcinoma of the cervix.
    American journal of clinical oncology, 1994, Volume: 17, Issue:2

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chemotherapy, Adjuvant; Cisplatin; Drug Administration Schedule; Female; Hematologic Diseases; Humans; Imides; Isoquinolines; Middle Aged; Naphthalimides; Organophosphonates; Pelvic Neoplasms; Treatment Outcome; Uterine Cervical Neoplasms

1994
A phase II trial of amonafide in patients with nonsquamous cell carcinoma of the cervix. A Gynecologic Oncology Group study.
    American journal of clinical oncology, 1997, Volume: 20, Issue:6

    Topics: Adenine; Adult; Antineoplastic Agents; Carcinoma; Female; Humans; Imides; Isoquinolines; Middle Aged; Naphthalimides; Organophosphonates; Uterine Cervical Neoplasms

1997
Cidofovir, a new approach for the treatment of cervix intraepithelial neoplasia grade III (CIN III).
    Journal of medical virology, 2000, Volume: 60, Issue:2

    Topics: Adult; Antiviral Agents; Biopsy; Cervix Uteri; Cidofovir; Conization; Cytosine; Female; Humans; Immunohistochemistry; Middle Aged; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Polymerase Chain Reaction; Tumor Virus Infections; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2000
Evaluation of amonafide in cervical cancer, phase II. A SWOG study.
    American journal of clinical oncology, 1992, Volume: 15, Issue:1

    Topics: Adenine; Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Imides; Isoquinolines; Middle Aged; Naphthalimides; Neoplasm Recurrence, Local; Organophosphonates; Survival Analysis; Uterine Cervical Neoplasms

1992

Other Studies

15 other study(ies) available for organophosphonates and Cancer of Cervix

ArticleYear
Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin inclusion complexes on bioadhesive film for cervical administration.
    International journal of pharmaceutics, 2017, Oct-15, Volume: 531, Issue:2

    Topics: Adenocarcinoma; Administration, Intravaginal; Antiviral Agents; Cell Line, Tumor; Cervix Uteri; Cidofovir; Cyclodextrins; Cytosine; Drug Delivery Systems; Female; Humans; Nanoparticles; Organophosphonates; Paclitaxel; Printing; Solubility; Uterine Cervical Neoplasms

2017
The combination of the antiviral agent cidofovir and anti-EGFR antibody cetuximab exerts an antiproliferative effect on HPV-positive cervical cancer cell lines' in-vitro and in-vivo xenografts.
    Anti-cancer drugs, 2013, Volume: 24, Issue:6

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antiviral Agents; Cell Cycle; Cell Line, Tumor; Cetuximab; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Organophosphonates; Papillomaviridae; Uterine Cervical Neoplasms

2013
Reduced tumorigenicity and pathogenicity of cervical carcinoma SiHa cells selected for resistance to cidofovir.
    Molecular cancer, 2013, Dec-10, Volume: 12

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cidofovir; Cytosine; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Resistance, Viral; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Mice; Mice, Nude; Organophosphonates; Phenotype; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2013
Resistance to the nucleotide analogue cidofovir in HPV(+) cells: a multifactorial process involving UMP/CMP kinase 1.
    Oncotarget, 2016, Mar-01, Volume: 7, Issue:9

    Topics: ATP-Binding Cassette Transporters; Cell Line, Tumor; Cidofovir; Cytidine Triphosphate; Cytosine; Drug Resistance, Neoplasm; Female; HeLa Cells; Humans; Microbial Sensitivity Tests; Nucleoside-Phosphate Kinase; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Phosphorylation; Solute Carrier Proteins; Uridine Triphosphate; Uterine Cervical Neoplasms

2016
Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms.
    Oncotarget, 2016, Jul-26, Volume: 7, Issue:30

    Topics: Antiviral Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cidofovir; Cytosine; DNA Damage; Female; Head and Neck Neoplasms; HeLa Cells; Humans; Male; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Squamous Cell Carcinoma of Head and Neck; Uterine Cervical Neoplasms

2016
Reduced cell viability and apoptosis induction in human thyroid carcinoma and mesothelioma cells exposed to cidofovir.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 41

    Topics: Antineoplastic Agents; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cidofovir; Cytosine; DNA Fragmentation; Female; Humans; Mesothelioma; Organophosphonates; Papillomavirus Infections; Polyomavirus Infections; Thyroid Neoplasms; Tumor Virus Infections; Uterine Cervical Neoplasms

2017
Cidofovir induces an increase in levels of low-risk and high-risk HPV E6.
    Head & neck, 2009, Volume: 31, Issue:7

    Topics: Antiviral Agents; Cell Culture Techniques; Cidofovir; Cytosine; Female; Human papillomavirus 6; Humans; Oncogene Proteins, Viral; Organophosphonates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Viral; Transfection; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2009
Antiproliferative effects of octadecyloxyethyl 9-[2-(phosphonomethoxy)ethyl]guanine against Me-180 human cervical cancer cells in vitro and in vivo.
    Chemotherapy, 2010, Volume: 56, Issue:1

    Topics: Adenine; Animals; Antineoplastic Agents; Female; Guanine; HeLa Cells; Humans; Mice; Mice, Nude; Organophosphonates; Organophosphorus Compounds; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2010
Effects of cidofovir on human papillomavirus-positive cervical cancer cells xenografts in nude mice.
    Oncology research, 2010, Volume: 18, Issue:11-12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cidofovir; Cytosine; Female; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Mice, Nude; Organophosphonates; Papillomaviridae; Proliferating Cell Nuclear Antigen; Tumor Suppressor Protein p53; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2010
Triphenylmethyl derivatives enhances the anticancer effect of immunotoxins.
    Journal of immunotherapy (Hagerstown, Md. : 1997), 2011, Volume: 34, Issue:5

    Topics: ADP Ribose Transferases; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bacterial Toxins; Breast Neoplasms; Caspase 3; Cell Line, Tumor; Cell Membrane; Cell Survival; Drug Synergism; ErbB Receptors; Exotoxins; Female; Humans; Immunotoxins; Mice; Mice, Nude; Neoplasm Transplantation; Organophosphonates; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Pseudomonas aeruginosa Exotoxin A; Rats; Rats, Nude; Skin Neoplasms; Stearoyl-CoA Desaturase; Trityl Compounds; Uterine Cervical Neoplasms; Virulence Factors

2011
Cidofovir treatment improves the pathology caused by the growth of human papillomavirus-positive cervical carcinoma xenografts in athymic nude mice.
    Cancer letters, 2013, Feb-28, Volume: 329, Issue:2

    Topics: Animals; Antineoplastic Agents; Brain; Cachexia; Carcinoma; Cell Line, Tumor; Cidofovir; Cytokines; Cytosine; Female; Human papillomavirus 16; Humans; Kynurenine; Leukocyte Count; Liver; Mice; Mice, Nude; Organophosphonates; Papillomavirus Infections; Spleen; Splenomegaly; Tryptophan; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2013
Enhanced antiproliferative effects of alkoxyalkyl esters of cidofovir in human cervical cancer cells in vitro.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:1

    Topics: Antineoplastic Agents; Cell Proliferation; Cidofovir; Cytosine; Drug Screening Assays, Antitumor; Esters; Female; Fibroblasts; HeLa Cells; Humans; Organophosphonates; Papillomavirus Infections; Tumor Cells, Cultured; Uterine Cervical Neoplasms

2006
Cidofovir administered with radiation displays an antiangiogenic effect mediated by E6 inhibition and subsequent TP53-dependent VEGF repression in HPV18+ cell lines.
    Radiation research, 2006, Volume: 166, Issue:4

    Topics: Angiogenic Proteins; Antineoplastic Agents; Cell Line, Tumor; Cidofovir; Cytosine; Down-Regulation; Female; Humans; Neovascularization, Pathologic; Organophosphonates; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A

2006
Inhibiting effects of cidofovir (HPMPC) on the growth of the human cervical carcinoma (SiHa) xenografts in athymic nude mice.
    Oncology research, 1998, Volume: 10, Issue:10

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cidofovir; Cytosine; Dose-Response Relationship, Drug; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Organophosphonates; Organophosphorus Compounds; Time Factors; Uterine Cervical Neoplasms

1998
Antiviral agent Cidofovir restores p53 function and enhances the radiosensitivity in HPV-associated cancers.
    Oncogene, 2002, Apr-04, Volume: 21, Issue:15

    Topics: Animals; Antiviral Agents; Carcinoma; Cell Division; Cidofovir; Cyclin A; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; Female; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Oncogene Proteins, Viral; Organophosphonates; Organophosphorus Compounds; Papillomaviridae; Papillomavirus Infections; Radiation-Sensitizing Agents; Radiation, Ionizing; Retinoblastoma Protein; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Virus Infections; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2002