Page last updated: 2024-09-05

organophosphonates and Adenoviridae Infections

organophosphonates has been researched along with Adenoviridae Infections in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (11.11)18.2507
2000's20 (37.04)29.6817
2010's25 (46.30)24.3611
2020's3 (5.56)2.80

Authors

AuthorsStudies
Baretta, V; Biffi, A; Calore, E; Caniglia, M; Capolsini, I; Carraro, F; Cesaro, S; Fagioli, F; Faraci, M; Galaverna, F; Locatelli, F; Massei, MS; Menconi, M; Pagliara, D; Perruccio, K; Soncini, E; Verna, M1
Fujimoto, T; Fukushima, K; Hanaoka, N; Hazama, M1
Gordon, YJ; Romanowski, EG; Yates, KA3
Spencer, JF; Tollefson, AE; Toth, K; Wold, WSM; Ying, B2
Attwood, C; Griffiths, PD; Irish, D; Kyriakou, C; Lowe, DM; Ramsay, ID1
Azar, MM; Hibbert, KA; Lane, RJ; Shepard, JO1
Abouljoud, MS; Nagai, S; Ramesh, M; Raoufi, M; Rizzari, MD; Safwan, M; Sulejmani, N1
Amit, S; Averbuch, D; Cherniak, M; Dar, D; Safadi, R; Sorek, R; Wolf, D1
Green, M; Lopez, SMC; Michaels, MG1
Cardona, DM; Detweiler, CJ; Mueller, SB; Prasad, VK; Saullo, JL; Sung, AD1
Alfson, ED; Awosika, OO; Ciarlini, P; Drew, C; Folkerth, RD; Johnson, EL; Klein, JP; Koo, S; Lyons, JL; Marty, F; Phillips, RE; Zaki, S1
Brock, E; Doern, C; Pugni, L; Ronchi, A; Sánchez, PJ1
Balakrishnan, L; Buller, RM; Capella, C; Dewhurst, S; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B1
Buller, RM; Spencer, JF; Tollefson, AE; Toth, K; Wold, WS; Ying, B1
Allard, A; Ljungman, P; Mattsson, J; Sparrelid, E; Swartling, L; Törlen, J1
Toth, K; Wold, WS1
Aitken, SL; Chemaly, RF; Ghantoji, SS; Jones, RB; Kontoyiannis, DP; Tam, VH; Zhou, J1
Kajon, AE; Lynch, JP1
Hayden, RT; Ison, MG1
Darr, S; Heim, A; Madisch, I1
Inoue, H; Ishikawa, M; Kadonosono, K; Sonoda, KH; Uchio, E1
Bauzon, M; Hermiston, T; Jin, F; Kretschmer, P1
Agwu, AL; Chen, AR; Dabb, AA; Higman, MA; Loeb, DM; Valsamakis, A; Williams, KM1
Patel, S; Slatter, M; Valappil, M; Waugh, S1
Bauerschmitz, GJ; Cerullo, V; Diaconu, I; Escutenaire, S; Hemminki, A; Hernandez-Alcoceba, R; Kanerva, A; Pesonen, S1
Engström, L; Lewensohn-Fuchs, I; Ljungman, P; Omar, H; Orvell, C; Pérez-Bercoff, L; Vuong, GK; Yun, Z1
Bhattacharjee, PS; Capriotti, JA; Clement, C; Foster, TP; Hill, JM; Hobden, JA; Kumar, M; Liang, B; Mahmud, R; Thompson, HW1
Bacon, CL; Irvine, AD; Keohane, C; Moran, B; Smith, OP1
Echavarria, M; Fishbein, M; Lynch, JP1
Anderson, M; Florescu, DF; Graham, ML; Guzman-Cottrill, JA; Johnston, C; Kurtzberg, J; Lanier, R; Lewinsohn, DA; Mommeja-Marin, H; Neely, MN; Painter, W; Papanicolaou, G; Pergam, SA; Qiu, F; Rigdon, J; Sande, J; van der Horst, C; Way, S1
El-Zoghby, Z; Herrmann, S; Keddis, M; Leung, N; Sethi, S1
Carter, BA; Chang, IF; Clark, BS; Demmler, GJ; Goss, JA; Heslop, HE; Karpen, SJ; Quiros-Tejeira, RE; Scott, JD; Seu, P1
Hatakeyama, N; Hori, T; Kudoh, T; Mizue, N; Suzuki, N; Tsutsumi, H1
Abe, M; Aoki, K; Iida, T; Kaneko, H; Mori, S; Ohno, S; Shigeta, S; Suzuki, O; Suzutani, T1
Ljungman, P1
Aoki, K; Eto, T; Gondo, H; Harada, M; Henzan, H; Kato, K; Miyamoto, T; Nagafuji, K; Nagatoshi, Y; Obama, K; Ohba, T1
Andrei, G; Balzarini, J; De Clercq, E; Hocková, D; Holý, A; Leyssen, P; Naesens, L; Neyts, J; Pannecouque, C; Snoeck, R; Ying, C1
Gordon, YJ; Irschick, EU; Nagl, M; Romanowski, EG; Teuchner, B; Yates, KA1
Keswani, M; Moudgil, A1
De Clercq, E; Geboes, L; Kelchtermans, H; Lenaerts, L; Matthys, P; Naesens, L; Verbeken, E1
Anderson, EJ; Guzman-Cottrill, JA; Katz, BZ; Kletzel, M; Sullivan, C; Thormann, K; Zheng, X1
Heim, A; Mattner, F; Meissner, B; Sykora, KW1
Buller, RM; Dhar, D; Painter, GR; Sagartz, JE; Spencer, JF; Toth, K; Wold, WS1
Araullo-Cruz, T; Gordon, YJ; Romanowski, EG1
de Oliveira, CB; LaBree, L; McDonnell, PJ; Stevenson, D; Trousdale, MD1
de Clercq, E; De Hauwere, B; Lutz, A; Maudgal, PC; Neyts, J1
Clark, NM; Greenson, JK; Hedderwick, SA; McGaughy, VR1
deWit, D; Emoto, N; Télémaque, S; Yanagisawa, M1
Araullo-Cruz, T; Gordon, YJ; Kinchington, PR; Romanowski, EG; Yates, KA1
Hoffman, JA; Kapoor, N; Ross, LA; Shah, AJ1
Araullo-Cruz, T; De Clercq, E; Gordon, YJ; Romanowski, E1

Reviews

7 review(s) available for organophosphonates and Adenoviridae Infections

ArticleYear
Disseminated adenovirus infection after allogeneic stem cell transplant and the potential role of brincidofovir - Case series and 10 year experience of management in an adult transplant cohort.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2017, Volume: 96

    Topics: Adenoviridae Infections; Adult; Antiviral Agents; Cohort Studies; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organophosphonates; Transplantation, Homologous; Treatment Outcome; Young Adult

2017
Adenovirus infection in pediatric transplant recipients: are effective antiviral agents coming our way?
    Current opinion in organ transplantation, 2018, Volume: 23, Issue:4

    Topics: Adenoviridae Infections; Antiviral Agents; Child; Cidofovir; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Organ Transplantation; Organophosphonates; Pediatrics; Transplant Recipients

2018
Neonatal adenoviral infection: a seventeen year experience and review of the literature.
    The Journal of pediatrics, 2014, Volume: 164, Issue:3

    Topics: Adenoviridae; Adenoviridae Infections; Age Factors; Antiviral Agents; Body Temperature; Cidofovir; Cohort Studies; Cough; Cytosine; Diarrhea; Fatigue; Female; Gastrointestinal Hemorrhage; Hepatomegaly; Humans; Hypotension; Hypoxia; Immunoglobulins, Intravenous; Infant, Newborn; Intensive Care Units, Neonatal; Irritable Mood; Male; Muscle Hypotonia; Organophosphonates; Pancytopenia; Polymerase Chain Reaction; Respiratory Sounds; Retrospective Studies; Ribavirin; Splenomegaly; Tachypnea; Vomiting

2014
Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention.
    Seminars in respiratory and critical care medicine, 2016, Volume: 37, Issue:4

    Topics: Adenoviridae; Adenoviridae Infections; Adenovirus Infections, Human; Adult; Antiviral Agents; Child; Cidofovir; Cytosine; Humans; Military Personnel; Organophosphonates; Prospective Studies; Respiratory Tract Infections; Serogroup; Viral Vaccines

2016
Adenovirus.
    Microbiology spectrum, 2016, Volume: 4, Issue:4

    Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Diagnostic Tests, Routine; Disease Susceptibility; Drug Monitoring; Humans; Immunocompromised Host; Organophosphonates

2016
Adenovirus.
    Seminars in respiratory and critical care medicine, 2011, Volume: 32, Issue:4

    Topics: Adenoviridae; Adenoviridae Infections; Adult; Age Factors; Antiviral Agents; Child; Cidofovir; Cytosine; Humans; Organophosphonates; Serotyping; Severity of Illness Index

2011
Treatment of adenovirus infections in the immunocompromised host.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2004, Volume: 23, Issue:8

    Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Clinical Trials as Topic; Cytosine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Ganciclovir; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Organ Transplantation; Organophosphonates; Organophosphorus Compounds; Prognosis; Ribavirin; Severity of Illness Index; Transplantation Immunology; Treatment Outcome; Vidarabine

2004

Trials

2 trial(s) available for organophosphonates and Adenoviridae Infections

ArticleYear
Cidofovir for treating adenoviral hemorrhagic cystitis in hematopoietic stem cell transplant recipients.
    Bone marrow transplantation, 2004, Volume: 34, Issue:10

    Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Antiviral Agents; Child; Cidofovir; Cystitis; Cytomegalovirus Infections; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Herpes Simplex; Humans; Male; Middle Aged; Opportunistic Infections; Organophosphonates; Treatment Outcome

2004
Adenoviral infections and a prospective trial of cidofovir in pediatric hematopoietic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2001, Volume: 7, Issue:7

    Topics: Adenoviridae Infections; Adolescent; Adult; Antiviral Agents; Child; Child, Preschool; Cidofovir; Cytosine; Female; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Organophosphonates; Organophosphorus Compounds; Prospective Studies; Retrospective Studies; Transplantation, Homologous; Treatment Outcome

2001

Other Studies

45 other study(ies) available for organophosphonates and Adenoviridae Infections

ArticleYear
Safety and efficacy of brincidofovir for Adenovirus infection in children receiving allogeneic stem cell transplantation: an AIEOP retrospective analyses.
    Bone marrow transplantation, 2021, Volume: 56, Issue:12

    Topics: Adenoviridae Infections; Antiviral Agents; Cytosine; Hematopoietic Stem Cell Transplantation; Humans; Organophosphonates; Retrospective Studies

2021
Sensitivity of Human Mastadenovirus, the Causal Agent of Pharyngoconjunctival Fever, Epidemic Keratoconjunctivitis, and Hemorrhagic Cystitis in Immunocompromised Individuals, to Brincidofovir.
    Microbiology spectrum, 2022, 02-23, Volume: 10, Issue:1

    Topics: Adenoviridae Infections; Adenovirus Infections, Human; Cystitis; Cytosine; Humans; Immunocompromised Host; Keratoconjunctivitis; Mastadenovirus; Organophosphonates

2022
Cyclopentenylcytosine (CPE-C): In Vitro and In Vivo Evaluation as an Antiviral against Adenoviral Ocular Infections.
    Molecules (Basel, Switzerland), 2023, Jun-29, Volume: 28, Issue:13

    Topics: Adenoviridae; Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cytosine; Eye Infections; Organophosphonates; Rabbits; Toxic Optic Neuropathy; Virus Replication

2023
HAdV-C6 Is a More Relevant Challenge Virus than HAdV-C5 for Testing Antiviral Drugs with the Immunosuppressed Syrian Hamster Model.
    Viruses, 2017, 06-13, Volume: 9, Issue:6

    Topics: A549 Cells; Adenoviridae Infections; Adenovirus Infections, Human; Adenoviruses, Human; Animals; Antiviral Agents; Cell Line; Cidofovir; Cricetinae; Cytosine; Disease Models, Animal; Ganciclovir; Humans; Immunosuppression Therapy; Liver; Male; Organophosphonates; Valganciclovir; Viral Load; Virus Replication

2017
Combination therapy with brincidofovir and valganciclovir against species C adenovirus infection in the immunosuppressed Syrian hamster model allows for substantial reduction of dose for both compounds.
    Antiviral research, 2017, Volume: 146

    Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cytosine; Disease Models, Animal; Drug Therapy, Combination; Ganciclovir; HEK293 Cells; Humans; Immunocompromised Host; Mesocricetus; Organophosphonates; Valganciclovir; Viral Load; Virus Replication

2017
Case 1-2018. A 39-Year-Old Woman with Rapidly Progressive Respiratory Failure.
    The New England journal of medicine, 2018, 01-11, Volume: 378, Issue:2

    Topics: Adenoviridae; Adenoviridae Infections; Adult; Antiviral Agents; Cidofovir; Cytosine; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Leukemia, Myeloid, Acute; Lung; Nasopharynx; Opportunistic Infections; Organophosphonates; Radiography, Thoracic; Renal Insufficiency; Respiratory Insufficiency; Stem Cell Transplantation; Tomography, X-Ray Computed; Viral Load

2018
Brincidofovir as Salvage Therapy for Adenovirus Disease in Intestinal Transplant Recipients.
    Pharmacotherapy, 2018, Volume: 38, Issue:4

    Topics: Adenoviridae Infections; Adult; Antiviral Agents; Cytosine; Female; Humans; Immunocompromised Host; Male; Organophosphonates; Salvage Therapy; Transplant Recipients

2018
Successful Brincidofovir Treatment of Metagenomics-detected Adenovirus Infection in a Severely Ill Signal Transducer and Activator of Transcription-1-deficient Patient.
    The Pediatric infectious disease journal, 2019, Volume: 38, Issue:3

    Topics: Adenoviridae Infections; Antiviral Agents; Cytosine; Humans; Immunocompromised Host; Liver; Male; Metagenomics; Organophosphonates; Osteomyelitis; STAT1 Transcription Factor; Treatment Outcome; Young Adult

2019
Brincidofovir (CMX001) Toxicity Associated With Epithelial Apoptosis and Crypt Drop Out in a Hematopoietic Cell Transplant Patient: Challenges in Distinguishing Drug Toxicity From GVHD.
    Journal of pediatric hematology/oncology, 2018, Volume: 40, Issue:6

    Topics: Adenoviridae; Adenoviridae Infections; Autografts; Child, Preschool; Colon; Cytosine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Medulloblastoma; Octreotide; Organophosphonates; Viremia

2018
Fatal adenovirus encephalomyeloradiculitis in an umbilical cord stem cell transplant recipient.
    Neurology, 2013, Apr-30, Volume: 80, Issue:18

    Topics: Adenoviridae Infections; Antiviral Agents; Cidofovir; Cord Blood Stem Cell Transplantation; Cytosine; Encephalomyelitis; Fatal Outcome; Female; Humans; Leukemia, Prolymphocytic, T-Cell; Middle Aged; Organophosphonates

2013
Ganciclovir inhibits human adenovirus replication and pathogenicity in permissive immunosuppressed Syrian hamsters.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:12

    Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Body Weight; Cell Line, Tumor; Cytosine; DNA-Directed DNA Polymerase; Female; Ganciclovir; Gene Expression; Humans; Immunocompromised Host; Male; Mesocricetus; Organophosphonates; Survival Analysis; Transaminases; Viral Load; Viral Proteins; Virus Replication

2014
Cidofovir and brincidofovir reduce the pathology caused by systemic infection with human type 5 adenovirus in immunosuppressed Syrian hamsters, while ribavirin is largely ineffective in this model.
    Antiviral research, 2014, Volume: 112

    Topics: Adenoviridae Infections; Adenoviruses, Human; Alanine Transaminase; Animals; Body Weight; Cell Line; Cidofovir; Cytosine; Disease Models, Animal; Female; Humans; Immunocompromised Host; Liver; Mesocricetus; Organophosphonates; Ribavirin; Survival Analysis; Treatment Outcome; Viral Load

2014
Prolonged outbreak of adenovirus A31 in allogeneic stem cell transplant recipients.
    Transplant infectious disease : an official journal of the Transplantation Society, 2015, Volume: 17, Issue:6

    Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Disease Outbreaks; DNA, Viral; Humans; Organophosphonates; Phylogeny; Retrospective Studies; Stem Cell Transplantation; Sweden; Time Factors

2015
New drug on the horizon for treating adenovirus.
    Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:14

    Topics: Adenoviridae Infections; Adenoviruses, Human; Adoptive Transfer; Animals; Antiviral Agents; Cidofovir; Cytosine; DNA, Viral; Humans; Immunocompromised Host; Organophosphonates; T-Lymphocytes

2015
Pharmacokinetics and safety of intravesicular cidofovir in allogeneic HSCT recipients.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:3

    Topics: Adenoviridae Infections; Administration, Intravesical; Adolescent; Aged; Antiviral Agents; Cidofovir; Cystitis; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Organophosphonates; Plasma; Prospective Studies; Transplantation, Homologous; Young Adult

2016
Antiviral activity of cidofovir and ribavirin against the new human adenovirus subtype 14a that is associated with severe pneumonia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Sep-01, Volume: 47, Issue:5

    Topics: Adenoviridae Infections; Adenoviruses, Human; Antiviral Agents; Cidofovir; Cytosine; Humans; Inhibitory Concentration 50; Organophosphonates; Pneumonia, Viral; Ribavirin; United States

2008
Clinical evaluation of local ocular toxicity in candidate anti-adenoviral agents in vivo.
    Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 2009, Volume: 223, Issue:4

    Topics: Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Eyelids; Female; Lacrimal Apparatus; Ophthalmic Solutions; Organophosphonates; Rabbits

2009
In vitro analysis of cidofovir and genetically engineered TK expression as potential approaches for the intervention of ColoAd1-based treatment of cancer.
    Gene therapy, 2009, Volume: 16, Issue:9

    Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Cell Survival; Cells, Cultured; Cidofovir; Cytosine; Genetic Engineering; Humans; Oncolytic Virotherapy; Oncolytic Viruses; Organophosphonates; Prodrugs; Ribavirin; Thymidine Kinase; Tumor Cells, Cultured

2009
The in vitro and in vivo evaluation of ddC as a topical antiviral for ocular adenovirus infections.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:11

    Topics: Adenoviridae Infections; Adenoviruses, Human; Administration, Topical; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Female; Humans; Organophosphonates; Rabbits; Tumor Cells, Cultured; Viral Plaque Assay; Virus Replication; Zalcitabine

2009
A clinical algorithm identifies high risk pediatric oncology and bone marrow transplant patients likely to benefit from treatment of adenoviral infection.
    Journal of pediatric hematology/oncology, 2009, Volume: 31, Issue:11

    Topics: Adenoviridae Infections; Algorithms; Antiviral Agents; Bone Marrow Transplantation; Child; Child, Preschool; Cidofovir; Cohort Studies; Cytosine; Female; Humans; Male; Organophosphonates; Retrospective Studies; Risk Factors; Transplantation, Autologous; Transplantation, Homologous

2009
Persistent adenoviraemia in an infant following haematopoietic stem cell transplantation.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, Volume: 47, Issue:1

    Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Cidofovir; Cytosine; Feces; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Lymphocyte Count; Male; Mothers; Organophosphonates; Severe Combined Immunodeficiency; Viral Load; Viremia

2010
Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir.
    The journal of gene medicine, 2010, Volume: 12, Issue:5

    Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Biological Transport; Cell Death; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorpromazine; Cidofovir; Cricetinae; Cytarabine; Cytosine; Humans; Immunocompetence; Mesocricetus; Neoplasms; Organ Specificity; Organophosphonates; Transduction, Genetic; Virus Replication

2010
Poor outcome of adenovirus infections in adult hematopoietic stem cell transplant patients with sustained adenovirus viremia.
    Transplant infectious disease : an official journal of the Transplantation Society, 2010, Volume: 12, Issue:5

    Topics: Adenoviridae Infections; Adult; Antiviral Agents; Asymptomatic Infections; Child; Child, Preschool; Cidofovir; Cohort Studies; Cytosine; DNA, Viral; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunocompromised Host; Male; Middle Aged; Organophosphonates; Polymerase Chain Reaction; Retrospective Studies; Ribavirin; Treatment Outcome; Viral Load; Viremia; Young Adult

2010
Clinical and antiviral efficacy of an ophthalmic formulation of dexamethasone povidone-iodine in a rabbit model of adenoviral keratoconjunctivitis.
    Investigative ophthalmology & visual science, 2011, Volume: 52, Issue:1

    Topics: Adenoviridae; Adenoviridae Infections; Animals; Anti-Infective Agents, Local; Cidofovir; Conjunctiva; Conjunctivitis, Viral; Cytosine; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Ophthalmic Solutions; Organophosphonates; Pharmaceutical Preparations; Povidone-Iodine; Rabbits; Tobramycin; Treatment Outcome; Viral Plaque Assay

2011
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome induced by cidofovir.
    Pediatric transplantation, 2011, Volume: 15, Issue:1

    Topics: Adenoviridae Infections; Cidofovir; Cytosine; Dermatitis, Exfoliative; Drug Eruptions; Eosinophilia; Female; Hematopoietic Stem Cell Transplantation; Humans; Infant; Organophosphonates; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Syndrome; Treatment Outcome

2011
Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012, Volume: 18, Issue:5

    Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Adult; Aged; Antiviral Agents; Child; Child, Preschool; Cytosine; Female; Humans; Immunocompromised Host; Infant; Male; Middle Aged; Organophosphonates; Retrospective Studies; Salvage Therapy; Severity of Illness Index; Stem Cell Transplantation; Transplantation, Homologous; Treatment Outcome; Viral Load

2012
Adenovirus-induced interstitial nephritis following umbilical cord blood transplant for chronic lymphocytic leukemia.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2012, Volume: 59, Issue:6

    Topics: Acute Kidney Injury; Adenoviridae Infections; Adult; Antineoplastic Combined Chemotherapy Protocols; Cidofovir; Cord Blood Stem Cell Transplantation; Cytosine; Fetal Blood; Follow-Up Studies; Humans; Immunocompromised Host; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Nephritis, Interstitial; Organophosphonates; Risk Assessment; Severity of Illness Index; Treatment Outcome; Unrelated Donors; Viremia

2012
Intravenous Cidofovir therapy for disseminated adenovirus in a pediatric liver transplant recipient.
    Transplantation, 2002, Oct-15, Volume: 74, Issue:7

    Topics: Adenoviridae; Adenoviridae Infections; Alanine Transaminase; Antiviral Agents; Blood; Child; Cidofovir; Cytosine; DNA, Viral; Female; Humans; Immunocompromised Host; Liver Transplantation; Organophosphonates; Organophosphorus Compounds

2002
Successful cidofovir treatment of adenovirus-associated hemorrhagic cystitis and renal dysfunction after allogenic bone marrow transplant.
    The Pediatric infectious disease journal, 2003, Volume: 22, Issue:10

    Topics: Acute Kidney Injury; Adenoviridae; Adenoviridae Infections; Bone Marrow Transplantation; Cidofovir; Cystitis; Cytosine; DNA, Viral; Dose-Response Relationship, Drug; Drug Administration Schedule; Follow-Up Studies; Hematuria; Humans; Male; Organophosphonates; Organophosphorus Compounds; Polymerase Chain Reaction; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Assessment; Transplantation, Homologous; Treatment Outcome

2003
The cotton rat model for adenovirus ocular infection: antiviral activity of cidofovir.
    Antiviral research, 2004, Volume: 61, Issue:1

    Topics: Adenoviridae Infections; Adenoviruses, Human; Administration, Topical; Animals; Antigens, Viral; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cornea; Cytosine; Disease Models, Animal; Drug Evaluation, Preclinical; Eye Infections, Viral; Female; Organophosphonates; Organophosphorus Compounds; Rats; Sigmodontinae; Viral Plaque Assay; Virus Replication; Virus Shedding

2004
Antiviral potential of a new generation of acyclic nucleoside phosphonates, the 6-[2-(phosphonomethoxy)alkoxy]-2,4-diaminopyrimidines.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Adenoviridae; Adenoviridae Infections; Animals; Anti-HIV Agents; Antiviral Agents; Cell Line; Cidofovir; Cytosine; HIV Infections; Humans; Mice; Mice, Nude; Models, Chemical; Moloney murine sarcoma virus; Organophosphonates; Papillomaviridae; Papillomavirus Infections; Poxviridae; Poxviridae Infections; Purines; Pyrimidines; Vaccinia; Vaccinia virus

2005
N-chlorotaurine is an effective antiviral agent against adenovirus in vitro and in the Ad5/NZW rabbit ocular model.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:5

    Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Cornea; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Eye Infections, Viral; Female; Keratitis; Ophthalmic Solutions; Organophosphonates; Rabbits; Taurine; Viral Plaque Assay; Virus Replication

2006
Adenovirus-associated hemorrhagic cystitis in a pediatric renal transplant recipient.
    Pediatric transplantation, 2007, Volume: 11, Issue:5

    Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Child, Preschool; Cidofovir; Cystitis; Cytosine; DNA, Viral; Follow-Up Studies; Hematuria; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Organophosphonates; Polymerase Chain Reaction; Postoperative Complications

2007
Recovery of humoral immunity is critical for successful antiviral therapy in disseminated mouse adenovirus type 1 infection.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:4

    Topics: 3T3 Cells; Adenoviridae; Adenoviridae Infections; Animals; Antibodies, Viral; Antiviral Agents; Cell Line; Cidofovir; Cyclophosphamide; Cytosine; Disease Models, Animal; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, SCID; Organophosphonates; Treatment Outcome

2008
High-risk adenovirus-infected pediatric allogeneic hematopoietic progenitor cell transplant recipients and preemptive cidofovir therapy.
    Pediatric transplantation, 2008, Volume: 12, Issue:2

    Topics: Adenoviridae; Adenoviridae Infections; Antiviral Agents; Case-Control Studies; Child; Cidofovir; Cytosine; Female; Hematopoietic Stem Cell Transplantation; Humans; Male; Organophosphonates; Prospective Studies; Risk Factors; Transplantation, Homologous

2008
An adenovirus type F41 outbreak in a pediatric bone marrow transplant unit: analysis of clinical impact and preventive strategies.
    The Pediatric infectious disease journal, 2008, Volume: 27, Issue:5

    Topics: Adenoviridae; Adenoviridae Infections; Adolescent; Antiviral Agents; Blood; Bone Marrow Transplantation; Capsid Proteins; Child; Child, Preschool; Cidofovir; Cross Infection; Cytosine; Disease Outbreaks; DNA, Viral; Feces; Gastroenteritis; Genotype; Germany; Hepatitis, Viral, Human; Humans; Infant; Organophosphonates; Sequence Analysis, DNA; Viral Load; Viremia; Virus Shedding

2008
Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, May-20, Volume: 105, Issue:20

    Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cricetinae; Cytosine; Disease Models, Animal; Drug Screening Assays, Antitumor; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Liver; Mesocricetus; Models, Biological; Organophosphonates

2008
Topical HPMPC inhibits adenovirus type 5 in the New Zealand rabbit ocular replication model.
    Investigative ophthalmology & visual science, 1994, Volume: 35, Issue:12

    Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Cytosine; Eye Infections, Viral; Female; Humans; Keratoconjunctivitis; Microbial Sensitivity Tests; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Replication; Virus Shedding

1994
Evaluation of Cidofovir (HPMPC, GS-504) against adenovirus type 5 infection in vitro and in a New Zealand rabbit ocular model.
    Antiviral research, 1996, Volume: 31, Issue:3

    Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antibodies, Viral; Cidofovir; Cytosine; Disease Models, Animal; Drug Evaluation; Enzyme-Linked Immunosorbent Assay; Eye; Female; Humans; Organophosphonates; Organophosphorus Compounds; Rabbits; Tears; Tumor Cells, Cultured

1996
An ocular model of Adenovirus type 5 infection in the rabbit.
    Bulletin de la Societe belge d'ophtalmologie, 1995, Volume: 259

    Topics: Adenine; Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Cytosine; Disease Models, Animal; Eye Diseases; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Replication

1995
Adenovirus cholecystitis in a patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:4

    Topics: Adenoviridae Infections; Adult; AIDS-Related Opportunistic Infections; Antiviral Agents; Cholecystitis; Cidofovir; Cytosine; Humans; Male; Organophosphonates; Organophosphorus Compounds

1998
In vivo role of endothelin-converting enzyme-1 as examined by adenovirus-mediated overexpression in rats.
    Journal of cardiovascular pharmacology, 1998, Volume: 31 Suppl 1

    Topics: Adenoviridae Infections; Animals; Aspartic Acid Endopeptidases; Azepines; Blood Pressure; Cattle; DNA, Complementary; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Humans; Hypertension; Indoles; Male; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Receptor, Endothelin A; Tetrazoles

1998
The antiviral resistance and replication of cidofovir-resistant adenovirus variants in the New Zealand White rabbit ocular model.
    Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:8

    Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Drug Resistance, Microbial; Female; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Cultivation; Virus Replication

2001
Antiviral prophylaxis with twice daily topical cidofovir protects against challenge in the adenovirus type 5/New Zealand rabbit ocular model.
    Antiviral research, 2001, Volume: 52, Issue:3

    Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Antiviral Agents; Cidofovir; Conjunctivitis, Viral; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Eye; Female; Organophosphonates; Organophosphorus Compounds; Rabbits; Virus Cultivation; Virus Replication

2001
Pretreatment with topical 0.1% (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine inhibits adenovirus type 5 replication in the New Zealand rabbit ocular model.
    Cornea, 1992, Volume: 11, Issue:6

    Topics: Adenoviridae; Adenoviridae Infections; Animals; Antiviral Agents; Cidofovir; Colony Count, Microbial; Corneal Diseases; Corneal Stroma; Cytosine; Disease Models, Animal; Eye Infections, Viral; Female; Ophthalmic Solutions; Organophosphonates; Organophosphorus Compounds; Premedication; Rabbits; Virus Replication

1992