Page last updated: 2024-09-05

orbofiban and Myocardial Infarction

orbofiban has been researched along with Myocardial Infarction in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's19 (95.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cannon, CP; Cox, D; Fitzgerald, DJ; Jneid, H; Maree, AO; Ryan, J; Shields, DC; Vangjeli, C1
Fitzgerald, A; Fitzgerald, DJ; Muckian, C; O'Byrne, A; O'Neill, A; Shields, DC1
Bentley, JH; Cannon, CP; Charlesworth, A; Kovar, D; Rogers, WJ1
Braunwauld, E; Cannon, CP; Cantor, WJ; Charlesworth, A; Goodman, SG; Langer, A; Murphy, SA1
Abernethy, DR; Cox, D; Fitzgerald, DJ; Mager, DE; Shirey, JD1
Cannon, CP; Feske, SK; Murphy, S; Schwamm, LH; Smith, EE1
Buros, JL; Cannon, CP; de Lemos, JA; Morrow, DA; Murphy, SA; O'Donoghue, M; Sabatine, MS1
Aster, RH; Brassard, J; Braunwald, E; Cannon, CP; Charlesworth, A; Cooper, R; McCabe, CH; Scirica, BM; Skene, AM1
Braunwald, E; Cannon, CP; de Lemos, JA; McCabe, CH; Morrow, DA; Murphy, S; Rifai, N; Sabatine, MS; Scirica, BM; Wiviott, SD1
Alexander, JC; Anders, RJ; Berink, P; Braunwald, E; Cannon, CP; Caspi, A; Charlesworth, A; Langer, A; Lopez-Sendon, J; McCabe, CH; Skene, A; Toman, J; Wilcox, RG1
Jang, IK; Sabatine, MS1
McGuire, DK; Newby, LK1
Bhatt, DL; Topol, EJ1
Cox, D; Crean, P; Fitzgerald, DJ; Quinn, M; Smith, R; Theroux, P1
Cannon, CP1
Bhatt, DL; Chew, DP; Sapp, S; Topol, EJ1
Bentley, JH; Braunwald, E; Cannon, CP; McCabe, CH; Wilcox, RG1
Anders, R; Burns, D; Kleiman, J; Nicholson, N; Wazowicz, B1
Braunwald, E; Cannon, CP; Fitzgerald, A; Fitzgerald, DJ; O'Connor, FF; Shields, DC1
Byrne, CE; Cannon, CP; Fitzgerald, AP; Fitzgerald, DJ; Kenny, D; Moran, B; Muckian, C; O'Neill, PA; Shields, DC1

Reviews

5 review(s) available for orbofiban and Myocardial Infarction

ArticleYear
The use of glycoprotein IIb/IIIa inhibitors in patients with coronary artery disease.
    The American journal of medicine, 2000, Aug-15, Volume: 109, Issue:3

    Topics: Abciximab; Acetates; Acute Disease; Administration, Oral; Alanine; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Benzamidines; Coronary Disease; Eptifibatide; Hemorrhage; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Oximes; Peptides; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic; Stents; Syndrome; Thrombocytopenia; Thrombolytic Therapy; Tirofiban; Tyrosine

2000
Oral platelet glycoprotein IIb/IIIa inhibition.
    Current cardiology reports, 2000, Volume: 2, Issue:5

    Topics: Alanine; Angina, Unstable; Aspirin; Benzamidines; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Humans; Myocardial Infarction; Oximes; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Syndrome; Treatment Outcome

2000
Current role of platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes.
    JAMA, 2000, Sep-27, Volume: 284, Issue:12

    Topics: Abciximab; Acute Disease; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Benzamidines; Drug Therapy, Combination; Eptifibatide; Heparin, Low-Molecular-Weight; Humans; Immunoglobulin Fab Fragments; Myocardial Infarction; Oximes; Peptides; Piperidines; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic; Stents; Tirofiban; Tyrosine

2000
Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials.
    Circulation, 2001, Jan-16, Volume: 103, Issue:2

    Topics: Administration, Oral; Alanine; Aspirin; Benzamidines; Clinical Trials, Phase III as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemorrhage; Humans; Incidence; Multicenter Studies as Topic; Myocardial Infarction; Oximes; Piperidines; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic

2001
Xemilofiban/orbofiban: insight into drug development.
    Cardiovascular drug reviews, 2001,Summer, Volume: 19, Issue:2

    Topics: Alanine; Angina, Unstable; Animals; Benzamidines; Bleeding Time; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Coronary Thrombosis; Drug Evaluation, Preclinical; Humans; Myocardial Infarction; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines

2001

Trials

11 trial(s) available for orbofiban and Myocardial Infarction

ArticleYear
Genetic variability in the extracellular matrix as a determinant of cardiovascular risk: association of type III collagen COL3A1 polymorphisms with coronary artery disease.
    Blood, 2002, Aug-15, Volume: 100, Issue:4

    Topics: Alanine; Alleles; Angina, Unstable; Collagen; Collagen Type III; Coronary Disease; Cross-Sectional Studies; Extracellular Matrix; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hemorrhage; Heterozygote; Humans; Minisatellite Repeats; Myocardial Infarction; Myocardial Ischemia; Placebos; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Pyrrolidines; Treatment Outcome

2002
Early cardiac catheterization is associated with lower mortality only among high-risk patients with ST- and non-ST-elevation acute coronary syndromes: observations from the OPUS-TIMI 16 trial.
    American heart journal, 2005, Volume: 149, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary Angiography; Coronary Artery Bypass; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Proportional Hazards Models; Pyrrolidines; Risk Factors; Stents; Survival Analysis

2005
Risk factors for stroke after acute coronary syndromes in the Orbofiban in Patients with Unstable Coronary Syndromes--Thrombolysis In Myocardial Infarction (OPUS-TIMI) 16 study.
    American heart journal, 2006, Volume: 151, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Cerebral Hemorrhage; Female; Fibrinolytic Agents; Follow-Up Studies; Humans; Ischemic Attack, Transient; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Proportional Hazards Models; Pyrrolidines; Risk Factors; Stroke; Syndrome; Thrombolytic Therapy

2006
Prognostic utility of heart-type fatty acid binding protein in patients with acute coronary syndromes.
    Circulation, 2006, Aug-08, Volume: 114, Issue:6

    Topics: Acute Disease; Adult; Alanine; Biomarkers; Fatty Acid-Binding Proteins; Female; Heart Failure; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Natriuretic Peptide, Brain; Odds Ratio; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Pyrrolidines; Risk Factors; Troponin I

2006
Drug-induced thrombocytopenia and thrombosis: evidence from patients receiving an oral glycoprotein IIb/IIIa inhibitor in the Orbofiban in Patients with Unstable coronary Syndromes- (OPUS-TIMI 16) trial.
    Journal of thrombosis and thrombolysis, 2006, Volume: 22, Issue:2

    Topics: Aged; Alanine; Angina, Unstable; Aspirin; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Thrombocytopenia; Thrombosis

2006
Clinical application of C-reactive protein across the spectrum of acute coronary syndromes.
    Clinical chemistry, 2007, Volume: 53, Issue:10

    Topics: Acute Disease; Aged; Alanine; Angina Pectoris; Angina, Unstable; C-Reactive Protein; Coronary Disease; Female; Follow-Up Studies; Heart Failure; Humans; Male; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Recurrence; Risk; Syndrome

2007
Oral glycoprotein IIb/IIIa inhibition with orbofiban in patients with unstable coronary syndromes (OPUS-TIMI 16) trial.
    Circulation, 2000, Jul-11, Volume: 102, Issue:2

    Topics: Administration, Oral; Alanine; Anticoagulants; Aspirin; Coronary Disease; Double-Blind Method; Female; Follow-Up Studies; Heparin; Humans; Intracranial Hemorrhages; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Stroke; Survival Analysis; Thrombocytopenia; Treatment Outcome

2000
Evidence of platelet activation during treatment with a GPIIb/IIIa antagonist in patients presenting with acute coronary syndromes.
    Journal of the American College of Cardiology, 2000, Nov-01, Volume: 36, Issue:5

    Topics: Acute Disease; Aged; Alanine; Angina, Unstable; Female; Humans; Male; Myocardial Infarction; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines

2000
Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris. OPUS-TIMI 16 Investigators.
    The American journal of cardiology, 2001, Mar-01, Volume: 87, Issue:5

    Topics: Aged; Alanine; Angina, Unstable; Female; Follow-Up Studies; Humans; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Pyrrolidines; Risk Factors; Survival Rate

2001
Genetic variation in glycoprotein IIb/IIIa (GPIIb/IIIa) as a determinant of the responses to an oral GPIIb/IIIa antagonist in patients with unstable coronary syndromes.
    Blood, 2001, Dec-01, Volume: 98, Issue:12

    Topics: Aged; Alanine; Angina, Unstable; Antigens, Human Platelet; Aspirin; Double-Blind Method; Female; Genetic Variation; Genotype; Hemorrhage; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Placebos; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Pyrrolidines

2001
The contribution of genetic factors to thrombotic and bleeding outcomes in coronary patients randomised to IIb/IIIa antagonists.
    The pharmacogenomics journal, 2002, Volume: 2, Issue:3

    Topics: Alanine; Coronary Disease; Genotype; Glycoproteins; Hemorrhage; Humans; Myocardial Infarction; Myocardial Revascularization; Platelet Glycoprotein GPIIb-IIIa Complex; Polymorphism, Genetic; Pyrrolidines; Recurrence; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; Stroke; Thrombosis; Treatment Outcome

2002

Other Studies

4 other study(ies) available for orbofiban and Myocardial Infarction

ArticleYear
G-protein beta3 subunit polymorphism and bleeding in the orbofiban in patients with unstable coronary syndromes-thrombolysis in myocardial infarction 16 trial.
    Journal of thrombosis and haemostasis : JTH, 2010, Volume: 8, Issue:5

    Topics: Alanine; Heart Diseases; Heterotrimeric GTP-Binding Proteins; Humans; Myocardial Infarction; Polymorphism, Genetic; Pyrrolidines; Thrombolytic Therapy

2010
Does initial and delayed heart rate predict mortality in patients with acute coronary syndromes?
    Clinical cardiology, 2004, Volume: 27, Issue:2

    Topics: Acute Disease; Alanine; Female; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Glycoprotein GPIIb-IIIa Complex; Predictive Value of Tests; Prognosis; Pyrrolidines; Syndrome

2004
Mapping the dose-effect relationship of orbofiban from sparse data with an artificial neural network.
    Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:11

    Topics: Alanine; Angina, Unstable; Dose-Response Relationship, Drug; Drug Monitoring; Female; Humans; Male; Middle Aged; Models, Biological; Myocardial Infarction; Neural Networks, Computer; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic; Reproducibility of Results

2005
Learning from the recently completed oral glycoprotein IIb/IIIa receptor antagonist trials.
    Clinical cardiology, 2000, Volume: 23 Suppl 6

    Topics: Alanine; Angina, Unstable; Benzamidines; Humans; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrrolidines; Randomized Controlled Trials as Topic; Syndrome; Treatment Outcome

2000