orabase and Jaw-Diseases

orabase has been researched along with Jaw-Diseases* in 1 studies

Other Studies

1 other study(ies) available for orabase and Jaw-Diseases

Article	Year
Modified protocol including topical minocycline in orabase to manage medication-related osteonecrosis of the jaw cases. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016, Volume: 45, Issue:9 Management of medication-related osteone-crosis of the jaw (MRONJ) with active infection can be a serious challenge for clinicians. Based on Association of Oral and Maxillofacial Surgeons (AAOMS) recommendations, we have tested a modified treatment protocol using topical minocycline.. Five patients diagnosed with stage II or III MRONJ lesions were willing to consent to our protocol. In addition to conventional treatment as suggested by the AAOMS, such as, surgical debridement, chlorhexidine irrigation, and systemic antibiotics, we applied 10% minocycline to the lesions once a week for sustained local antibiotic delivery.. All five patients reported pain relief after the first minocycline application. Complete healing occurred in three patients; case three healed completely after the third application, one case continues to improve toward resolution and one withdraws due to other non-relevant medical problem.. In this study, we are reporting favorable results using a modified protocol with topical minocycline to treat MRONJ lesions. Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carboxymethylcellulose Sodium; Drug Administration Schedule; Female; Humans; Jaw Diseases; Minocycline; Osteonecrosis; Treatment Outcome	2016

Article

Year

Modified protocol including topical minocycline in orabase to manage medication-related osteonecrosis of the jaw cases.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2016, Volume: 45, Issue:9

Management of medication-related osteone-crosis of the jaw (MRONJ) with active infection can be a serious challenge for clinicians. Based on Association of Oral and Maxillofacial Surgeons (AAOMS) recommendations, we have tested a modified treatment protocol using topical minocycline.. Five patients diagnosed with stage II or III MRONJ lesions were willing to consent to our protocol. In addition to conventional treatment as suggested by the AAOMS, such as, surgical debridement, chlorhexidine irrigation, and systemic antibiotics, we applied 10% minocycline to the lesions once a week for sustained local antibiotic delivery.. All five patients reported pain relief after the first minocycline application. Complete healing occurred in three patients; case three healed completely after the third application, one case continues to improve toward resolution and one withdraws due to other non-relevant medical problem.. In this study, we are reporting favorable results using a modified protocol with topical minocycline to treat MRONJ lesions.

Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carboxymethylcellulose Sodium; Drug Administration Schedule; Female; Humans; Jaw Diseases; Minocycline; Osteonecrosis; Treatment Outcome

2016