orabase and Influenza-in-Birds

orabase has been researched along with Influenza-in-Birds* in 2 studies

Other Studies

2 other study(ies) available for orabase and Influenza-in-Birds

Article	Year
Emerging viruses: risk of pandemic. Expert review of anti-infective therapy, 2008, Volume: 6, Issue:5 The International Consortium on Anti-Virals (ICAV) is a nonprofit organization that aims to support the development of antivirals for life-threatening and emerging viruses. In recent years, ICAV's emphasis has been predominantly on tropical viruses and avian influenza. The Sixth International Symposium of the ICAV was held at Trent University, Peterborough, Canada, and at MaRs Discovery District, Toronto, Canada, 4-6 May 2008. Approximately 100 participants representing 12 countries attended the symposium. This meeting report focuses on two thought-provoking presentations on topics that require immediate attention: the development of potent broad-spectrum antivirals against emerging viruses and the assessment of the risk of a H5N1 influenza pandemic. Topics: Animals; Antiviral Agents; Carboxymethylcellulose Sodium; Chickens; Communicable Diseases, Emerging; Disease Outbreaks; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Liposomes; Mice; Peptides; Poultry Diseases; Risk; Virus Diseases; Viruses	2008
Nucleic acid-based antiviral drugs against seasonal and avian influenza viruses. Vaccine, 2007, Apr-20, Volume: 25, Issue:16 Influenza viruses are etiological agents of deadly flu that continue to pose global health threats, and have caused global pandemics that killed millions of people worldwide. The availability of neuraminidase inhibitors and attenuated vaccines improves our ability to defend against influenza, but their benefits can be significantly limited by drug-resistance and virus mutations. Nucleic acid-based drugs may represent a promising class of antiviral agents that could play a role in the prevention and treatment of influenza. Efficacy studies in animals have shown that ds RNA, such as poly ICLC can provide effective and broad-spectrum prophylaxis against lethal challenges against various strains of influenza A virus. Furthermore, similar level of antiviral protection in mice can be provided by using short fragments of oligonucleotides that induce antiviral immunity. Finally, influenza virus expression can also be specifically inhibited or suppressed using antisense oligonucleotides that bind to viral mRNA encoding key viral proteins. The versatility and potency of nucleic acid-based drugs make them potential drug candidates for used in seasonal or pandemic influenza situations. Topics: Animals; Antiviral Agents; Birds; Carboxymethylcellulose Sodium; Humans; Influenza A virus; Influenza in Birds; Influenza, Human; Liposomes; Mice; Oligodeoxyribonucleotides; Poly I-C; Polylysine	2007

Article

Year

Expert review of anti-infective therapy, 2008, Volume: 6, Issue:5

The International Consortium on Anti-Virals (ICAV) is a nonprofit organization that aims to support the development of antivirals for life-threatening and emerging viruses. In recent years, ICAV's emphasis has been predominantly on tropical viruses and avian influenza. The Sixth International Symposium of the ICAV was held at Trent University, Peterborough, Canada, and at MaRs Discovery District, Toronto, Canada, 4-6 May 2008. Approximately 100 participants representing 12 countries attended the symposium. This meeting report focuses on two thought-provoking presentations on topics that require immediate attention: the development of potent broad-spectrum antivirals against emerging viruses and the assessment of the risk of a H5N1 influenza pandemic.

Topics: Animals; Antiviral Agents; Carboxymethylcellulose Sodium; Chickens; Communicable Diseases, Emerging; Disease Outbreaks; Humans; Influenza A Virus, H5N1 Subtype; Influenza in Birds; Influenza, Human; Liposomes; Mice; Peptides; Poultry Diseases; Risk; Virus Diseases; Viruses

2008

Nucleic acid-based antiviral drugs against seasonal and avian influenza viruses.

Vaccine, 2007, Apr-20, Volume: 25, Issue:16

Influenza viruses are etiological agents of deadly flu that continue to pose global health threats, and have caused global pandemics that killed millions of people worldwide. The availability of neuraminidase inhibitors and attenuated vaccines improves our ability to defend against influenza, but their benefits can be significantly limited by drug-resistance and virus mutations. Nucleic acid-based drugs may represent a promising class of antiviral agents that could play a role in the prevention and treatment of influenza. Efficacy studies in animals have shown that ds RNA, such as poly ICLC can provide effective and broad-spectrum prophylaxis against lethal challenges against various strains of influenza A virus. Furthermore, similar level of antiviral protection in mice can be provided by using short fragments of oligonucleotides that induce antiviral immunity. Finally, influenza virus expression can also be specifically inhibited or suppressed using antisense oligonucleotides that bind to viral mRNA encoding key viral proteins. The versatility and potency of nucleic acid-based drugs make them potential drug candidates for used in seasonal or pandemic influenza situations.

Topics: Animals; Antiviral Agents; Birds; Carboxymethylcellulose Sodium; Humans; Influenza A virus; Influenza in Birds; Influenza, Human; Liposomes; Mice; Oligodeoxyribonucleotides; Poly I-C; Polylysine

2007