orabase and Glaucoma

orabase has been researched along with Glaucoma* in 1 studies

Other Studies

1 other study(ies) available for orabase and Glaucoma

Article	Year
[Antiglaucoma ophthalmic agents with prolonged action based on macromolecular excipients. 1. In vitro studies]. Die Pharmazie, 1990, Volume: 45, Issue:8 Hydrogels and Hydrosols based on sodium carboxymethyl-cellulose (NaCMC), polyvinylpyrrolidone (PVP) and polyacrylic acids (PAS) Carbopol 940, Scopacryl D 339 (PAS-B) and PAS-Fluka (PAS-F) were investigated in vitro for rheological properties and pilocarpine release. The gels showed diffusion coefficients in the series Carbopol 940 1% greater than NaCMC 3% greater than PAS-F 3.5% greater than PVP K 90 23% greater than PAS-B 8% greater than PAS-F 7%. Especially PAS-F proved suitable for prolonged release, also in liquid preparations. Lyophilizated pilocarpine polymer-salts which were prepared from PAS-F and pilocarpine base, both in effect of retardation and in drug stability showed important advantages compared with aqueous solution of pilocarpine. Topics: Acrylic Resins; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Drug Stability; Excipients; Glaucoma; Hydrogen-Ion Concentration; Models, Chemical; Ophthalmic Solutions; Pilocarpine; Povidone; Sterilization; Viscosity	1990

Article

Year

[Antiglaucoma ophthalmic agents with prolonged action based on macromolecular excipients. 1. In vitro studies].

Die Pharmazie, 1990, Volume: 45, Issue:8

Hydrogels and Hydrosols based on sodium carboxymethyl-cellulose (NaCMC), polyvinylpyrrolidone (PVP) and polyacrylic acids (PAS) Carbopol 940, Scopacryl D 339 (PAS-B) and PAS-Fluka (PAS-F) were investigated in vitro for rheological properties and pilocarpine release. The gels showed diffusion coefficients in the series Carbopol 940 1% greater than NaCMC 3% greater than PAS-F 3.5% greater than PVP K 90 23% greater than PAS-B 8% greater than PAS-F 7%. Especially PAS-F proved suitable for prolonged release, also in liquid preparations. Lyophilizated pilocarpine polymer-salts which were prepared from PAS-F and pilocarpine base, both in effect of retardation and in drug stability showed important advantages compared with aqueous solution of pilocarpine.

Topics: Acrylic Resins; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Drug Stability; Excipients; Glaucoma; Hydrogen-Ion Concentration; Models, Chemical; Ophthalmic Solutions; Pilocarpine; Povidone; Sterilization; Viscosity

1990