orabase and Atrophy

Trial vocal fold injection (TVFI) may be used prior to permanent medialization when voice outcome is uncertain. We aimed to determine whether voice outcomes of TVFI are predictive of, or correlate with outcomes after type I Gore-Tex medialization thyroplasty (GMT) in patients with nonparalytic glottic incompetence (GI).. Thirty-five patients with nonparalytic GI who underwent TVFI followed by GMT were retrospectively reviewed. Change in voice-related quality of life (VRQOL) after TVFI was compared to change in VRQOL 3 to 9 months after GMT. Similar comparisons were made for change in glottal function index (GFI) and change in grade, roughness, breathiness, asthenia, and strain (GRBAS). Sample correlation coefficients were calculated.. Change in VRQOL after TVFI showed good correlation with change in VRQOL after GMT, r = 0.55. Change in GFI after TVFI showed strong correlation with change in GFI after GMT, r = 0.74. Change in GRBAS after TVFI showed excellent correlation with change in GRBAS after GMT, r = 0.90.. The TVFI is a useful tool in nonparalytic GI when outcomes from glottic closure procedures are not clear. Voice outcome measures after TVFI strongly correlate with outcomes from GMT. These data may be used to more confidently counsel patients regarding their predicted outcomes of permanent medialization.

Topics: Atrophy; Carboxymethylcellulose Sodium; Cicatrix; Collagen; Female; Gelatin Sponge, Absorbable; Glottis; Humans; Laryngeal Diseases; Laryngoplasty; Male; Middle Aged; Polytetrafluoroethylene; Prognosis; Quality of Life; Retrospective Studies; Treatment Outcome; Vocal Cord Paralysis; Vocal Cords; Voice

To compare voice outcomes after vocal fold augmentation using a trial (temporary) vocal fold injection (VFI) versus long-term augmentation in patients diagnosed with vocal fold atrophy.. Retrospective, single-blinded study.. Nineteen patients diagnosed with vocal fold atrophy underwent trial VFI and subsequent long-term augmentation. Voice Handicap Index-10, acoustic, and aerodynamic measures were analyzed following trial and long-term augmentation procedures.. Forty-two percent (8/19) of patients had a good response to trial VFI (P < .0001); 58% (11/19) had a poor response to trial VFI (P = .95). Of the patients with good response to trial VFI, 75% (6/8) also had good response to long-term augmentation (P = .006), but 25% (2/8) reported a poor response to long-term treatment. Of the patients who had a poor response to trial VFI, 55% (6/11) also had a poor response to long-term treatment, but 45% (5/11) of patients reported good response after long-term augmentation.. This is the first study to provide comparative voice outcomes using both trial VFI and long-term augmentation for vocal fold atrophy. Additional critical evaluation of the value of trial VFI for vocal fold atrophy patients is suggested.

Topics: Aged; Aged, 80 and over; Atrophy; Carboxymethylcellulose Sodium; Female; Follow-Up Studies; Humans; Hyaluronic Acid; Injections, Intralesional; Laryngeal Diseases; Laryngoscopy; Male; Middle Aged; Retrospective Studies; Single-Blind Method; Time Factors; Treatment Outcome; Vocal Cords; Voice Disorders; Voice Quality