opc 12759 has been researched along with Xerostomia in 3 studies
rebamipide: structure in first source; RN refers to (+-)-isomer; inhibits gastric xanthine oxidase
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| " No difference in the incidence of adverse events was seen between the two groups, confirming the safety of rebamipide." | 2.74 | Efficacy and safety of rebamipide for the treatment of dry mouth symptoms in patients with Sjögren's syndrome: a double-blind placebo-controlled multicenter trial. ( Kawakami, A; Koni, I; Nishinarita, M; Nishiyama, S; Ohta, S; Oka, H; Sawada, S; Sugai, S; Sugiyama, E; Takahashi, H; Takei, M; Umehara, H; Yamaji, K, 2009) |
| "This study aimed to detect safety signals of rebamipide and search for adverse events (AEs) of rebamipide that are more common than those of other drugs for peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD) in the elderly population." | 1.72 | Frequently reported adverse events of rebamipide compared to other drugs for peptic ulcer and gastroesophageal reflux disease. ( Jang, E; Jeong, JE; Kim, MG; Lee, JY; Park, M, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Jang, E | 1 |
| Park, M | 1 |
| Jeong, JE | 1 |
| Lee, JY | 1 |
| Kim, MG | 1 |
| Ogane, M | 1 |
| Okubo, M | 1 |
| Yoshikawa, M | 1 |
| Shinomiya, T | 1 |
| Tsukagoshi, E | 1 |
| Kawaguchi, M | 1 |
| Sugai, S | 1 |
| Takahashi, H | 1 |
| Ohta, S | 1 |
| Nishinarita, M | 1 |
| Takei, M | 1 |
| Sawada, S | 1 |
| Yamaji, K | 1 |
| Oka, H | 1 |
| Umehara, H | 1 |
| Koni, I | 1 |
| Sugiyama, E | 1 |
| Nishiyama, S | 1 |
| Kawakami, A | 1 |
1 trial available for opc 12759 and Xerostomia
| Article | Year |
|---|---|
Efficacy and safety of rebamipide for the treatment of dry mouth symptoms in patients with Sjögren's syndrome: a double-blind placebo-controlled multicenter trial.
Topics: Aged; Alanine; Anti-Inflammatory Agents; Double-Blind Method; Eating; Female; Humans; Male; Middle A | 2009 |
2 other studies available for opc 12759 and Xerostomia
| Article | Year |
|---|---|
Frequently reported adverse events of rebamipide compared to other drugs for peptic ulcer and gastroesophageal reflux disease.
Topics: Adverse Drug Reaction Reporting Systems; Aged; Alanine; Gastroesophageal Reflux; Humans; Peptic Ulce | 2022 |
Rebamipide, an anti-ulcerative drug, inhibits induction of salivary dysfunction by benzodiazepines.
Topics: Alanine; Animals; Anti-Ulcer Agents; Central Nervous System Agents; Diazepam; Dose-Response Relation | 2017 |