opc 12759 has been researched along with Ulcer in 8 studies
rebamipide: structure in first source; RN refers to (+-)-isomer; inhibits gastric xanthine oxidase
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers." | 3.11 | The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study. ( Choi, YJ; Ha, YJ; Kang, EH; Kim, HS; Kim, KJ; Kim, N; Lee, DH; Lee, YJ; Liu, F; Oh, DJ; Park, YS; Shin, CM; Yoon, H, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Oh, DJ | 1 |
| Yoon, H | 1 |
| Kim, HS | 1 |
| Choi, YJ | 1 |
| Shin, CM | 1 |
| Park, YS | 1 |
| Kim, N | 2 |
| Lee, DH | 1 |
| Ha, YJ | 1 |
| Kang, EH | 1 |
| Lee, YJ | 1 |
| Kim, KJ | 1 |
| Liu, F | 1 |
| Jung, DH | 1 |
| Park, JC | 1 |
| Lee, YC | 1 |
| Lee, SK | 1 |
| Shin, SK | 1 |
| Chung, H | 1 |
| Park, JJ | 1 |
| Kim, JH | 1 |
| Youn, YH | 1 |
| Park, H | 1 |
| Xu, N | 1 |
| Zhang, C | 1 |
| Jing, L | 1 |
| Mou, S | 1 |
| Cao, X | 1 |
| Yu, Z | 1 |
| Fujimoto, A | 1 |
| Uraoka, T | 1 |
| Yahagi, N | 1 |
| Dong, T | 1 |
| Zhao, L | 1 |
| Liu, L | 1 |
| Fan, Z | 1 |
| Otani, K | 1 |
| Tanigawa, T | 1 |
| Watanabe, T | 1 |
| Shimada, S | 1 |
| Nadatani, Y | 1 |
| Nagami, Y | 1 |
| Tanaka, F | 1 |
| Kamata, N | 1 |
| Yamagami, H | 1 |
| Shiba, M | 1 |
| Tominaga, K | 1 |
| Fujiwara, Y | 1 |
| Arakawa, T | 1 |
| Kawai, T | 1 |
| Yamagishi, T | 1 |
| Goto, S | 1 |
| Takagi, T | 1 |
| Naito, Y | 1 |
| Uchiyama, K | 1 |
| Okuda, T | 1 |
| Mizushima, K | 1 |
| Suzuki, T | 1 |
| Handa, O | 1 |
| Ishikawa, T | 1 |
| Yagi, N | 1 |
| Kokura, S | 1 |
| Ichikawa, H | 1 |
| Yoshikawa, T | 1 |
1 review available for opc 12759 and Ulcer
| Article | Year |
|---|---|
Microbiota Plays a Key Role in Non-Steroidal Anti-Inflammatory Drug-Induced Small Intestinal Damage.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Gastrointestinal Microbiome; Hu | 2017 |
3 trials available for opc 12759 and Ulcer
| Article | Year |
|---|---|
The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Intestinal Diseases; Pilot Projects; Ulcer | 2022 |
Comparison of the Efficacy of Polaprezinc Plus Proton Pump Inhibitor and Rebamipide Plus Proton Pump Inhibitor Treatments for Endoscopic Submucosal Dissection-induced Ulcers.
Topics: Alanine; Anti-Ulcer Agents; Carnosine; Drug Therapy, Combination; Endoscopic Mucosal Resection; Huma | 2021 |
Circadian variations of gastrointestinal mucosal damage detected with transnasal endoscopy in apparently healthy subjects treated with low-dose aspirin (ASA) for a short period.
Topics: Adult; Alanine; Aspirin; Circadian Rhythm; Double-Blind Method; Endoscopy; Female; Gastric Mucosa; H | 2009 |
4 other studies available for opc 12759 and Ulcer
| Article | Year |
|---|---|
Protective effect and mechanism of rebamipide on NSAIDs associated small bowel injury.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Claudin-1; Cytokines; Diclofenac; Disease | 2021 |
Response.
Topics: Alanine; Endoscopic Mucosal Resection; Humans; Quinolones; Ulcer | 2019 |
Submucosal injection materials other than mucosal lift.
Topics: Alanine; Endoscopic Mucosal Resection; Humans; Mucous Membrane; Quinolones; Ulcer | 2019 |
Rebamipide promotes healing of colonic ulceration through enhanced epithelial restitution.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Line; Colon; Epithelial Cells; Intestinal Mucosa; Male; Qu | 2011 |