opc 12759 has been researched along with Stomatitis, Aphthous in 2 studies
rebamipide: structure in first source; RN refers to (+-)-isomer; inhibits gastric xanthine oxidase
Stomatitis, Aphthous: A recurrent disease of the oral mucosa of unknown etiology. It is characterized by small white ulcerative lesions, single or multiple, round or oval. Two to eight crops of lesions occur per year, lasting for 7 to 14 days and then heal without scarring. (From Jablonski's Dictionary of Dentistry, 1992, p742)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral aphthae count and pain scores were recorded daily in a diary by the patients themselves." | 2.71 | Efficacy of rebamipide as adjunctive therapy in the treatment of recurrent oral aphthous ulcers in patients with Behçet's disease: a randomised, double-blind, placebo-controlled study. ( Hirohata, S; Inaba, G; Kogure, M; Matsuda, T; Miyanaga, Y; Mizushima, Y; Nakamura, S; Ohno, S; Tanaka, S; Ujihara, H, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Taylor, J | 1 |
| Glenny, AM | 1 |
| Walsh, T | 1 |
| Brocklehurst, P | 1 |
| Riley, P | 1 |
| Gorodkin, R | 1 |
| Pemberton, MN | 1 |
| Matsuda, T | 1 |
| Ohno, S | 1 |
| Hirohata, S | 1 |
| Miyanaga, Y | 1 |
| Ujihara, H | 1 |
| Inaba, G | 1 |
| Nakamura, S | 1 |
| Tanaka, S | 1 |
| Kogure, M | 1 |
| Mizushima, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Topical Rebamipide Versus Topical Betamethasone for Management of Oral Ulcers in Behcet's Disease: A Randomized Clinical Trial[NCT06084624] | Phase 1/Phase 2 | 40 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for opc 12759 and Stomatitis, Aphthous
| Article | Year |
|---|---|
Interventions for the management of oral ulcers in Behçet's disease.
Topics: Acyclovir; Adrenal Cortex Hormones; Alanine; Behcet Syndrome; Colchicine; Cyclosporine; Etanercept; | 2014 |
1 trial available for opc 12759 and Stomatitis, Aphthous
| Article | Year |
|---|---|
Efficacy of rebamipide as adjunctive therapy in the treatment of recurrent oral aphthous ulcers in patients with Behçet's disease: a randomised, double-blind, placebo-controlled study.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Behcet Syndrome; Double-Blind Method; Drug Therapy, Combina | 2003 |