opc 12759 has been researched along with Innate Inflammatory Response in 10 studies
rebamipide: structure in first source; RN refers to (+-)-isomer; inhibits gastric xanthine oxidase
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic inflammation affecting the lesser curvature of the corpus was significantly improved in the rebamipide group compared to in the untreated group (1." | 2.80 | Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study. ( Akiyama, T; Haruma, K; Hata, J; Inoue, K; Ito, M; Kamada, T; Manabe, N; Matsumoto, H; Murao, T; Sato, M; Shiotani, A; Tanaka, S; Tokutomi, T; Watanabe, T, 2015) |
| "Obesity is a medical term used to describe an over-accumulation of adipose tissue." | 1.72 | Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes. ( Cho, KH; Cho, ML; Choi, J; Jhun, J; Jung, YJ; Kim, SY; Min, JK; Moon, J; Na, HS; Song, KY, 2022) |
| "To determine the mucinogenic effect of dry eye (DE) treatment drugs currently in use, we compared the levels of mucin production and inflammatory cytokine expression on the ocular surfaces using a DE-induced mice model." | 1.48 | Comparison of Ocular Surface Mucin Expression After Topical Ophthalmic Drug Administration in Dry Eye-Induced Mouse Model. ( Ji, YW; Kang, HG; Kim, HC; Lee, HK; Moon, I; Noh, H; Song, JS; Yeo, A, 2018) |
| "Mucosal inflammation is a crucial factor for the recurrence of peptic ulcer." | 1.33 | Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils. ( Osaka, T; Sakurai, K; Yamasaki, K, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jhun, J | 2 |
| Moon, J | 1 |
| Kim, SY | 2 |
| Cho, KH | 1 |
| Na, HS | 2 |
| Choi, J | 1 |
| Jung, YJ | 1 |
| Song, KY | 1 |
| Min, JK | 2 |
| Cho, ML | 3 |
| Moon, I | 1 |
| Kang, HG | 1 |
| Yeo, A | 1 |
| Noh, H | 1 |
| Kim, HC | 1 |
| Song, JS | 1 |
| Ji, YW | 1 |
| Lee, HK | 1 |
| Ueta, M | 1 |
| Sotozono, C | 1 |
| Yokoi, N | 1 |
| Kinoshita, S | 1 |
| Kamada, T | 1 |
| Sato, M | 1 |
| Tokutomi, T | 1 |
| Watanabe, T | 1 |
| Murao, T | 1 |
| Matsumoto, H | 1 |
| Manabe, N | 1 |
| Ito, M | 1 |
| Tanaka, S | 1 |
| Inoue, K | 1 |
| Shiotani, A | 1 |
| Akiyama, T | 1 |
| Hata, J | 1 |
| Haruma, K | 1 |
| Kim, SK | 1 |
| Choe, JY | 1 |
| Park, KY | 1 |
| Min, HK | 1 |
| Kim, JK | 1 |
| Lee, SY | 1 |
| Kim, EK | 2 |
| Lee, SH | 2 |
| Lee, J | 1 |
| Kwok, SK | 1 |
| Park, SH | 1 |
| Kwon, JE | 1 |
| Jeong, JH | 1 |
| Jung, K | 1 |
| Bang, D | 1 |
| Choi, B | 1 |
| Kwon, HJ | 1 |
| Lee, ES | 1 |
| Lee, S | 1 |
| Sohn, S | 1 |
| Kang, DW | 1 |
| Min, G | 1 |
| Park, DY | 1 |
| Hong, KW | 1 |
| Min, do S | 1 |
| Sakurai, K | 1 |
| Osaka, T | 1 |
| Yamasaki, K | 1 |
1 trial available for opc 12759 and Innate Inflammatory Response
| Article | Year |
|---|---|
Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Female; Gastritis; Helicobacter Infections; Helicobacter py | 2015 |
9 other studies available for opc 12759 and Innate Inflammatory Response
| Article | Year |
|---|---|
Rebamipide treatment ameliorates obesity phenotype by regulation of immune cells and adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Diet, High-Fat; Inflammation; Insulin Resistance; | 2022 |
Comparison of Ocular Surface Mucin Expression After Topical Ophthalmic Drug Administration in Dry Eye-Induced Mouse Model.
Topics: Administration, Topical; Alanine; Animals; Anti-Inflammatory Agents; Cyclosporine; Disease Models, A | 2018 |
Rebamipide suppresses PolyI:C-stimulated cytokine production in human conjunctival epithelial cells.
Topics: Alanine; Animals; Antioxidants; Conjunctiva; Conjunctivitis, Allergic; Cytokines; Disease Models, An | 2013 |
Rebamipide Suppresses Monosodium Urate Crystal-Induced Interleukin-1β Production Through Regulation of Oxidative Stress and Caspase-1 in THP-1 Cells.
Topics: Alanine; Ascorbic Acid; Caspase 1; Cell Line; Colchicine; Dexamethasone; Enzyme Activation; Gout; Hu | 2016 |
Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis.
Topics: Alanine; Animals; Arthritis, Experimental; beta-Glucans; Cytokines; Inflammation; Inflammation Media | 2016 |
Rebamipide ameliorates atherosclerosis by controlling lipid metabolism and inflammation.
Topics: Alanine; Animals; Antioxidants; Aorta; Apolipoproteins E; Arthritis; Atherosclerosis; Collagen; Foam | 2017 |
Rebamipide affects the efficiency of colchicine for the herpes simplex virus-induced inflammation in a Behcet's disease mouse model.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Colchicine; Enzyme-Linke | 2008 |
Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells.
Topics: Alanine; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplast | 2010 |
Rebamipide reduces recurrence of experimental gastric ulcers: role of free radicals and neutrophils.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Free Radicals; Gastric Mucosa; Glutathione Peroxid | 2005 |