opc 12759 has been researched along with Gastritis in 20 studies
rebamipide: structure in first source; RN refers to (+-)-isomer; inhibits gastric xanthine oxidase
Gastritis: Inflammation of the GASTRIC MUCOSA, a lesion observed in a number of unrelated disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| " pylori-infected chronic gastritis by preventing the production of inflammatory cytokines and chemokines, as does cimetidine, but may be preferable to cimetidine for long-term administration for treatment of H." | 7.72 | Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils. ( Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Matsumoto, T; Oshitani, N; Sasaki, E; Shiba, M; Takashima, T; Tanigawa, T; Tominaga, K; Watanabe, T, 2003) |
| "Among the 15 patients with hemorrhagic acute gastritis who were randomly allocated to group A (eradication therapy) or group B (Lansoprazole, LPZ), 10 of them started to receive treatment within 1 day after the disease onset." | 5.09 | A short-term eradication therapy for Helicobacter pylori acute gastritis. ( Asaka, M; Kashiwagi, S; Miyake, K; Nomura, H; Sugiyama, T, 2000) |
| " pylori-infected chronic gastritis by preventing the production of inflammatory cytokines and chemokines, as does cimetidine, but may be preferable to cimetidine for long-term administration for treatment of H." | 3.72 | Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils. ( Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Matsumoto, T; Oshitani, N; Sasaki, E; Shiba, M; Takashima, T; Tanigawa, T; Tominaga, K; Watanabe, T, 2003) |
| "Chronic inflammation affecting the lesser curvature of the corpus was significantly improved in the rebamipide group compared to in the untreated group (1." | 2.80 | Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study. ( Akiyama, T; Haruma, K; Hata, J; Inoue, K; Ito, M; Kamada, T; Manabe, N; Matsumoto, H; Murao, T; Sato, M; Shiotani, A; Tanaka, S; Tokutomi, T; Watanabe, T, 2015) |
| "Improvement of gastritis is expressed not only in quantity but also in quality of gastritis, which is shown as the reduction of iNOS expression in the gastric mucosa." | 2.42 | Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide. ( Haruma, K; Ito, M, 2003) |
| "Pretreatment with omeprazole (30 mg/kg s." | 1.30 | Influence of rebamipide on indometacin-induced gastric hemorrhage in rats under restraint stress. ( Arakawa, T; Higuchi, K; Kobayashi, K; Kuroki, T; Takaishi, O; Yamasaki, K, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 11 (55.00) | 29.6817 |
| 2010's | 5 (25.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, Q | 1 |
| Liu, M | 1 |
| Rong, Z | 1 |
| Liang, H | 1 |
| Xu, X | 1 |
| Sun, S | 1 |
| Lei, Y | 1 |
| Li, P | 1 |
| Meng, H | 1 |
| Zheng, R | 1 |
| Bi, Y | 1 |
| Chen, X | 2 |
| Wang, B | 2 |
| Zhao, J | 1 |
| Jiang, K | 2 |
| Kim, GH | 1 |
| Lee, HL | 1 |
| Joo, MK | 1 |
| Park, HJ | 1 |
| Jung, SW | 1 |
| Lee, OJ | 1 |
| Kim, H | 1 |
| Chun, HJ | 1 |
| Lee, ST | 1 |
| Kim, JW | 1 |
| Jeon, HH | 1 |
| Chung, IK | 1 |
| Kim, HS | 1 |
| Lee, DH | 1 |
| Kim, KO | 1 |
| Lim, YJ | 1 |
| Park, SJ | 1 |
| Cho, SJ | 1 |
| Kim, BW | 1 |
| Ko, KH | 1 |
| Jeon, SW | 1 |
| Kim, JG | 1 |
| Sung, IK | 1 |
| Kim, TN | 1 |
| Sung, JK | 1 |
| Park, JJ | 1 |
| Nishizawa, T | 1 |
| Nishizawa, Y | 1 |
| Yahagi, N | 1 |
| Kanai, T | 1 |
| Takahashi, M | 1 |
| Suzuki, H | 1 |
| Kamada, T | 1 |
| Sato, M | 1 |
| Tokutomi, T | 1 |
| Watanabe, T | 2 |
| Murao, T | 1 |
| Matsumoto, H | 1 |
| Manabe, N | 2 |
| Ito, M | 3 |
| Tanaka, S | 2 |
| Inoue, K | 1 |
| Shiotani, A | 1 |
| Akiyama, T | 1 |
| Hata, J | 1 |
| Haruma, K | 3 |
| Han, X | 1 |
| Zhou, L | 1 |
| Li, S | 1 |
| Naito, Y | 2 |
| Yoshikawa, T | 3 |
| Jung, K | 1 |
| Chin, YW | 1 |
| Chung, YH | 1 |
| Park, YH | 1 |
| Yoo, H | 1 |
| Min, DS | 1 |
| Lee, B | 1 |
| Kim, J | 1 |
| Genta, RM | 1 |
| Higuchi, K | 2 |
| Tanigawa, T | 1 |
| Hamaguchi, M | 1 |
| Takashima, T | 1 |
| Sasaki, E | 1 |
| Shiba, M | 1 |
| Tominaga, K | 1 |
| Fujiwara, Y | 1 |
| Oshitani, N | 1 |
| Matsumoto, T | 1 |
| Arakawa, T | 3 |
| Hahm, KB | 2 |
| Kim, DH | 1 |
| Lee, KM | 1 |
| Lee, JS | 1 |
| Surh, YJ | 1 |
| Kim, YB | 1 |
| Yoo, BM | 1 |
| Kim, JH | 1 |
| Joo, HJ | 1 |
| Cho, YK | 1 |
| Nam, KT | 1 |
| Cho, SW | 1 |
| Fujioka, T | 1 |
| Shimoyama, T | 1 |
| Itoh, M | 1 |
| Asaka, M | 2 |
| Ishii, H | 1 |
| Kuwayama, H | 1 |
| Sato, R | 1 |
| Kawai, S | 1 |
| Takemoto, T | 1 |
| Kobayashi, K | 2 |
| Matysiak-Budnik, T | 1 |
| van Niel, G | 1 |
| Mégraud, F | 1 |
| Mayo, K | 1 |
| Bevilacqua, C | 1 |
| Gaboriau-Routhiau, V | 1 |
| Moreau, MC | 1 |
| Heyman, M | 1 |
| Park, S | 1 |
| Oh, TY | 1 |
| Jin, JH | 1 |
| Choue, R | 1 |
| Du, Y | 1 |
| Li, Z | 1 |
| Zhan, X | 1 |
| Chen, J | 1 |
| Gao, J | 1 |
| Gong, Y | 1 |
| Ren, J | 1 |
| He, L | 1 |
| Zhang, Z | 1 |
| Guo, X | 1 |
| Wu, J | 1 |
| Tian, Z | 1 |
| Shi, R | 1 |
| Jiang, B | 1 |
| Fang, D | 1 |
| Li, Y | 1 |
| Chitapanarux, T | 1 |
| Praisontarangkul, OA | 1 |
| Lertprasertsuke, N | 1 |
| Iinuma, S | 1 |
| Miyazaki, R | 1 |
| Yagi, N | 1 |
| Yoshida, N | 1 |
| Osumi, T | 1 |
| Hirao, Y | 1 |
| Kondo, M | 1 |
| Yamasaki, K | 1 |
| Takaishi, O | 1 |
| Kuroki, T | 1 |
| Nomura, H | 1 |
| Miyake, K | 1 |
| Kashiwagi, S | 1 |
| Sugiyama, T | 1 |
| Kido, S | 1 |
| Kitadai, Y | 1 |
| Sumii, M | 1 |
| Yoshihara, M | 1 |
| Chayama, K | 1 |
3 reviews available for opc 12759 and Gastritis
| Article | Year |
|---|---|
Effect of supplementation with rebamipide for Helicobacter pylori eradication therapy: a systematic review and meta-analysis.
Topics: Alanine; Amoxicillin; Databases, Bibliographic; Drug Therapy, Combination; Gastritis; Helicobacter I | 2014 |
Effect of supplementation with rebamipide for Helicobacter pylori eradication therapy: a systematic review and meta-analysis.
Topics: Alanine; Amoxicillin; Databases, Bibliographic; Drug Therapy, Combination; Gastritis; Helicobacter I | 2014 |
Review article: the role of rebamipide in the management of inflammatory disease of the gastrointestinal tract.
Topics: Alanine; Anti-Ulcer Agents; Cells, Cultured; Clinical Trials as Topic; Colitis; Gastritis; Helicobac | 2003 |
Review article: the role of rebamipide in the management of inflammatory disease of the gastrointestinal tract.
Topics: Alanine; Anti-Ulcer Agents; Cells, Cultured; Clinical Trials as Topic; Colitis; Gastritis; Helicobac | 2003 |
Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Anticarcinogenic Agents; Gastri | 2003 |
Review article: clinical significance of mucosal-protective agents: acid, inflammation, carcinogenesis and rebamipide.
Topics: Alanine; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Anticarcinogenic Agents; Gastri | 2003 |
9 trials available for opc 12759 and Gastritis
| Article | Year |
|---|---|
Efficacy and Safety of Rebamipide versus Its New Formulation, AD-203, in Patients with Erosive Gastritis: A Randomized, Double-Blind, Active Control, Noninferiority, Multicenter, Phase 3 Study.
Topics: Alanine; Double-Blind Method; Gastritis; Humans; Quinolones; Stomach Ulcer; Treatment Outcome | 2021 |
Efficacy and Safety of Rebamipide versus Its New Formulation, AD-203, in Patients with Erosive Gastritis: A Randomized, Double-Blind, Active Control, Noninferiority, Multicenter, Phase 3 Study.
Topics: Alanine; Double-Blind Method; Gastritis; Humans; Quinolones; Stomach Ulcer; Treatment Outcome | 2021 |
Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Female; Gastritis; Helicobacter Infections; Helicobacter py | 2015 |
Rebamipide improves chronic inflammation in the lesser curvature of the corpus after Helicobacter pylori eradication: a multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Female; Gastritis; Helicobacter Infections; Helicobacter py | 2015 |
Effect of Rebamipide on the Premalignant Progression of Chronic Gastritis: A Randomized Controlled Study.
Topics: Alanine; CDX2 Transcription Factor; Disease Progression; Female; Gastric Mucosa; Gastritis; Helicoba | 2015 |
Effect of Rebamipide on the Premalignant Progression of Chronic Gastritis: A Randomized Controlled Study.
Topics: Alanine; CDX2 Transcription Factor; Disease Progression; Female; Gastric Mucosa; Gastritis; Helicoba | 2015 |
Effects of rebamipide, a gastro-protective drug on the Helicobacter pylori status and inflammation in the gastric mucosa of patients with gastric ulcer: a randomized double-blind placebo-controlled multicentre trial.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Double-Blind Method; Female; Gastric Mucosa; Gastritis; Hel | 2003 |
Effects of rebamipide, a gastro-protective drug on the Helicobacter pylori status and inflammation in the gastric mucosa of patients with gastric ulcer: a randomized double-blind placebo-controlled multicentre trial.
Topics: Adult; Aged; Alanine; Anti-Ulcer Agents; Double-Blind Method; Female; Gastric Mucosa; Gastritis; Hel | 2003 |
Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study.
Topics: Adult; Alanine; Anti-Inflammatory Agents; Anti-Ulcer Agents; China; Dinoprostone; Female; Gastric Mu | 2008 |
Anti-inflammatory effects of rebamipide according to Helicobacter pylori status in patients with chronic erosive gastritis: a randomized sucralfate-controlled multicenter trial in China-STARS study.
Topics: Adult; Alanine; Anti-Inflammatory Agents; Anti-Ulcer Agents; China; Dinoprostone; Female; Gastric Mu | 2008 |
An open-labeled study of rebamipide treatment in chronic gastritis patients with dyspeptic symptoms refractory to proton pump inhibitors.
Topics: Adult; Alanine; Anti-Ulcer Agents; Chronic Disease; Dyspepsia; Endoscopy, Gastrointestinal; Endpoint | 2008 |
An open-labeled study of rebamipide treatment in chronic gastritis patients with dyspeptic symptoms refractory to proton pump inhibitors.
Topics: Adult; Alanine; Anti-Ulcer Agents; Chronic Disease; Dyspepsia; Endoscopy, Gastrointestinal; Endpoint | 2008 |
Local gastric and serum concentrations of rebamipide following oral administration to patients with chronic gastritis.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Ch | 1996 |
Local gastric and serum concentrations of rebamipide following oral administration to patients with chronic gastritis.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Ch | 1996 |
A short-term eradication therapy for Helicobacter pylori acute gastritis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Adolescent; Adult; Alanine; Amoxicillin; Ant | 2000 |
A short-term eradication therapy for Helicobacter pylori acute gastritis.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Adolescent; Adult; Alanine; Amoxicillin; Ant | 2000 |
Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis.
Topics: Alanine; Anti-Ulcer Agents; Drug Administration Schedule; Gastrins; Gastritis; Helicobacter Infectio | 2002 |
Long-term rebamipide therapy improves Helicobacter pylori-associated chronic gastritis.
Topics: Alanine; Anti-Ulcer Agents; Drug Administration Schedule; Gastrins; Gastritis; Helicobacter Infectio | 2002 |
8 other studies available for opc 12759 and Gastritis
| Article | Year |
|---|---|
Rebamipide attenuates alcohol-induced gastric epithelial cell injury by inhibiting endoplasmic reticulum stress and activating autophagy-related proteins.
Topics: Alanine; Animals; Anti-Ulcer Agents; Autophagy-Related Proteins; Endoplasmic Reticulum Stress; Epith | 2022 |
Rebamipide attenuates alcohol-induced gastric epithelial cell injury by inhibiting endoplasmic reticulum stress and activating autophagy-related proteins.
Topics: Alanine; Animals; Anti-Ulcer Agents; Autophagy-Related Proteins; Endoplasmic Reticulum Stress; Epith | 2022 |
Rebamipide: a gastrointestinal protective drug with pleiotropic activities.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Alendronate; Allopurinol; Animals; Anti-Inflammatory Agents | 2010 |
Rebamipide: a gastrointestinal protective drug with pleiotropic activities.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Alendronate; Allopurinol; Animals; Anti-Inflammatory Agents | 2010 |
Anti-gastritis and wound healing effects of Momordicae Semen extract and its active component.
Topics: Alanine; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Gastric Mucosa; Gastritis; Hel | 2013 |
Anti-gastritis and wound healing effects of Momordicae Semen extract and its active component.
Topics: Alanine; Animals; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Gastric Mucosa; Gastritis; Hel | 2013 |
Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chemokines; Cimetidine; Gastrins; Gastritis; Gerbillinae; Helic | 2003 |
Comparison of the effects of rebamipide with those of cimetidine on chronic gastritis associated with Helicobacter pylori in Mongolian gerbils.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chemokines; Cimetidine; Gastrins; Gastritis; Gerbillinae; Helic | 2003 |
Effect of long-term administration of rebamipide on Helicobacter pylori infection in mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Blotting, Western; Cytokines; Gastric Mucosa; Gastri | 2003 |
Effect of long-term administration of rebamipide on Helicobacter pylori infection in mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Blotting, Western; Cytokines; Gastric Mucosa; Gastri | 2003 |
Gastric Helicobacter infection inhibits development of oral tolerance to food antigens in mice.
Topics: Administration, Oral; Alanine; Anaphylaxis; Animals; Antigen Presentation; Antigens; Chickens; Femal | 2003 |
Gastric Helicobacter infection inhibits development of oral tolerance to food antigens in mice.
Topics: Administration, Oral; Alanine; Anaphylaxis; Animals; Antigen Presentation; Antigens; Chickens; Femal | 2003 |
Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Arachidonic Acid; Cyclooxygenase 2; Cytoprotection; | 2004 |
Preventive effect of the flavonoid, wogonin, against ethanol-induced gastric mucosal damage in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Apoptosis; Arachidonic Acid; Cyclooxygenase 2; Cytoprotection; | 2004 |
Influence of rebamipide on indometacin-induced gastric hemorrhage in rats under restraint stress.
Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catalas | 1999 |
Influence of rebamipide on indometacin-induced gastric hemorrhage in rats under restraint stress.
Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Catalas | 1999 |