opc 12759 has been researched along with Colitis in 10 studies
rebamipide: structure in first source; RN refers to (+-)-isomer; inhibits gastric xanthine oxidase
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to examine the efficacy of rebamipide on acetic acid-induced colitis in rats." | 7.70 | Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity. ( Osaka, T; Sakurai, K; Yamasaki, K, 1998) |
| "The aim of this study was to examine the efficacy of rebamipide on acetic acid-induced colitis in rats." | 3.70 | Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity. ( Osaka, T; Sakurai, K; Yamasaki, K, 1998) |
| "Radiation-induced colitis is a common clinical problem associated with radiotherapy and accidental exposure to ionizing radiation." | 1.48 | Rebamipide alleviates radiation-induced colitis through improvement of goblet cell differentiation in mice. ( Jang, H; Jang, WS; Jin, YW; Kim, H; Lee, C; Lee, J; Lee, SJ; Lee, SS; Myung, H; Myung, JK; Park, S; Shim, S, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jang, H | 1 |
| Park, S | 1 |
| Lee, J | 1 |
| Myung, JK | 1 |
| Jang, WS | 1 |
| Lee, SJ | 1 |
| Myung, H | 1 |
| Lee, C | 1 |
| Kim, H | 1 |
| Lee, SS | 1 |
| Jin, YW | 1 |
| Shim, S | 1 |
| Hossain, MA | 1 |
| Yamashita, M | 1 |
| Vong, LB | 1 |
| Ikeda, Y | 1 |
| Nagasaki, Y | 1 |
| Genta, RM | 1 |
| Okayama, M | 1 |
| Tsubouchi, R | 1 |
| Nishio, H | 1 |
| Kato, S | 1 |
| Takeuchi, K | 1 |
| Nakamura, M | 1 |
| Takahashi, T | 1 |
| Matsumoto, T | 1 |
| Atsuda, K | 1 |
| Hibi, N | 1 |
| Matsui, H | 1 |
| Yamada, H | 1 |
| Tsuchimoto, K | 1 |
| Murai, R | 1 |
| Kanbe, T | 1 |
| Mukoyama, T | 1 |
| Shimomura, T | 1 |
| Hashiguchi, K | 1 |
| Yoshida, Y | 1 |
| Tsuchiya, H | 1 |
| Hoshikawa, Y | 1 |
| Kurimasa, A | 1 |
| Shiota, G | 1 |
| Zea-Iriarte, WL | 1 |
| Makiyama, K | 1 |
| Goto, S | 1 |
| Murase, K | 1 |
| Urata, Y | 1 |
| Sekine, I | 1 |
| Hara, K | 1 |
| Kondo, T | 1 |
| Sakurai, K | 2 |
| Osaka, T | 1 |
| Yamasaki, K | 1 |
| Iwai, A | 1 |
| Iwashita, E | 1 |
| Kishimoto, S | 1 |
| Haruma, K | 1 |
| Tari, A | 1 |
| Nakano, M | 1 |
| Nakagawa, Y | 1 |
1 review available for opc 12759 and Colitis
| Article | Year |
|---|---|
Review article: the role of rebamipide in the management of inflammatory disease of the gastrointestinal tract.
Topics: Alanine; Anti-Ulcer Agents; Cells, Cultured; Clinical Trials as Topic; Colitis; Gastritis; Helicobac | 2003 |
9 other studies available for opc 12759 and Colitis
| Article | Year |
|---|---|
Rebamipide alleviates radiation-induced colitis through improvement of goblet cell differentiation in mice.
Topics: Alanine; Animals; Anti-Ulcer Agents; Cell Differentiation; Cell Proliferation; Colitis; Colon; Disea | 2018 |
Silica-installed redox nanoparticles for novel oral nanotherapeutics - improvement in intestinal delivery with anti-inflammatory effects.
Topics: Administration, Oral; Alanine; Animals; Anti-Inflammatory Agents; Colitis; Colon; Delayed-Action Pre | 2014 |
Protective effect of intra-rectal administration of rebamipide on dextran sulfate sodium-induced rat colitis.
Topics: Administration, Rectal; Alanine; Animals; Anti-Ulcer Agents; Anticoagulants; Colitis; Dextran Sulfat | 2004 |
Direct autoradiographic evidence that rebamipide interacts with neutrophils in dextran sulfate sodium induced colitis in rats.
Topics: Administration, Oral; Alanine; Animals; Anti-Ulcer Agents; Colitis; Dextran Sulfate; Disease Models, | 2005 |
Effect of rectal administration of rebamipide on dextran sulfate sodium-induced colitis: role of hepatocyte growth factor.
Topics: Administration, Rectal; Alanine; Animals; Anticoagulants; Apoptosis; Cell Proliferation; Colitis; De | 2007 |
Impairment of antioxidants in colonic epithelial cells isolated from trinitrobenzene sulphonic acid-induced colitis rats. Protective effect of rebamipide.
Topics: Alanine; Analysis of Variance; Animals; Anti-Ulcer Agents; Antioxidants; Colitis; Culture Techniques | 1996 |
Protection by rebamipide against acetic acid-induced colitis in rats: relationship with its antioxidative activity.
Topics: Acetic Acid; Alanine; Animals; Anti-Ulcer Agents; Antioxidants; Colitis; Intestinal Mucosa; Lipid Pe | 1998 |
Changes in colonic inflammation induced by dextran sulfate sodium (DSS) during short- and long-term administration of rebamipide.
Topics: Acute Disease; Alanine; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Anticoagulants; Chroni | 1998 |
Rebamipide, an antiulcer drug, prevents DSS-induced colitis formation in rats.
Topics: Alanine; Animals; Anti-Ulcer Agents; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Interl | 2000 |