opc 12759 has been researched along with Alzheimer Disease in 1 studies
rebamipide: structure in first source; RN refers to (+-)-isomer; inhibits gastric xanthine oxidase
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fukui, K | 1 |
| Yachi, K | 1 |
| Yoshida, H | 1 |
| Tanji, K | 1 |
| Matsumiya, T | 1 |
| Hayakari, R | 1 |
| Tsuruga, K | 1 |
| Tanaka, H | 1 |
| Imaizumi, T | 1 |
1 other study available for opc 12759 and Alzheimer Disease
| Article | Year |
|---|---|
Rebamipide reduces amyloid-β 1-42 (Aβ42) production and ameliorates Aβ43-lowered cell viability in cultured SH-SY5Y human neuroblastoma cells.
Topics: Alanine; Alzheimer Disease; Amyloid beta-Peptides; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2 | 2017 |