ono 1078 has been researched along with Pulmonary Eosinophilia in 4 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Pulmonary Eosinophilia: A condition characterized by infiltration of the lung with EOSINOPHILS due to inflammation or other disease processes. Major eosinophilic lung diseases are the eosinophilic pneumonias caused by infections, allergens, or toxic agents.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Allergic airway eosinophilia is suppressed by cysteinyl leukotriene (CysLT) receptor (CysLT1 receptor) antagonists in several species including humans and guinea-pigs, suggesting that CysLTs are directly or indirectly involved in induction of the response." | 1.31 | Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs. ( Kawai, T; Kohno, S; Miura, M; Nabe, T; Yamashita, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakagawa, N | 1 |
| Obata, T | 1 |
| Kobayashi, T | 1 |
| Okada, Y | 1 |
| Nambu, F | 1 |
| Terawaki, T | 1 |
| Furuya, T | 1 |
| Muryobayashi, K | 1 |
| Sawada, M | 1 |
| Aishita, H | 1 |
| Underwood, DC | 1 |
| Osborn, RR | 1 |
| Newsholme, SJ | 1 |
| Torphy, TJ | 1 |
| Hay, DW | 1 |
| Nabe, T | 1 |
| Yamashita, K | 1 |
| Miura, M | 1 |
| Kawai, T | 1 |
| Kohno, S | 1 |
| Asano, M | 1 |
| Inamura, N | 1 |
| Nakahara, K | 1 |
| Nagayoshi, A | 1 |
| Isono, T | 1 |
| Hamada, K | 1 |
| Oku, T | 1 |
| Notsu, Y | 1 |
| Kohsaka, M | 1 |
| Ono, T | 1 |
4 other studies available for ono 1078 and Pulmonary Eosinophilia
| Article | Year |
|---|---|
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrict | 1993 |
Persistent airway eosinophilia after leukotriene (LT) D4 administration in the guinea pig: modulation by the LTD4 receptor antagonist, pranlukast, or an interleukin-5 monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Chromones; Cyclo | 1996 |
Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs.
Topics: Animals; Asthma; Cell Survival; Chromones; Cysteine; Eosinophilia; Guinea Pigs; Interleukin-5; Kinet | 2002 |
A 5-lipoxygenase inhibitor, FR110302, suppresses airway hyperresponsiveness and lung eosinophilia induced by Sephadex particles in rats.
Topics: Acetylcholine; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Chromones; Dextrans | 1992 |