ono 1078 has been researched along with Otitis Media with Effusion in 2 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "all ears developed middle ear effusion (MEE) within 24 h and about 50% of the animals continued to demonstrate MEE for 14 days in the 1x10(-4) and 2x10(-4) M groups." | 5.31 | Experimental otitis media with effusion induced by leukotriene D4. ( Adachi, Y; Arai, S; Furukawa, M; Ikehara, S; Ogura, M; Tada, N; Yamashita, T, 2002) |
| "Conventional treatment for acute otitis media mainly targets bacteria with antibiotics, neglecting to control for mediators of inflammation." | 2.82 | The effect of the leukotriene antagonist pranlukast on pediatric acute otitis media. ( Esaki, S; Hamajima, Y; Miyamoto, N; Murakami, S; Nakamura, Y; Nakayama, M; Oshika, M; Sugiyama, K; Suzuki, M; Takagi, I; Yasui, K; Yokota, M, 2016) |
| "all ears developed middle ear effusion (MEE) within 24 h and about 50% of the animals continued to demonstrate MEE for 14 days in the 1x10(-4) and 2x10(-4) M groups." | 1.31 | Experimental otitis media with effusion induced by leukotriene D4. ( Adachi, Y; Arai, S; Furukawa, M; Ikehara, S; Ogura, M; Tada, N; Yamashita, T, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, Y | 1 |
| Hamajima, Y | 1 |
| Suzuki, M | 1 |
| Esaki, S | 1 |
| Yokota, M | 1 |
| Oshika, M | 1 |
| Takagi, I | 1 |
| Yasui, K | 1 |
| Miyamoto, N | 1 |
| Sugiyama, K | 1 |
| Nakayama, M | 1 |
| Murakami, S | 1 |
| Tada, N | 1 |
| Furukawa, M | 1 |
| Ogura, M | 1 |
| Arai, S | 1 |
| Adachi, Y | 1 |
| Ikehara, S | 1 |
| Yamashita, T | 1 |
1 trial available for ono 1078 and Otitis Media with Effusion
| Article | Year |
|---|---|
The effect of the leukotriene antagonist pranlukast on pediatric acute otitis media.
Topics: Acute Disease; Anti-Bacterial Agents; Child; Child, Preschool; Chromones; Disease Progression; Drug | 2016 |
1 other study available for ono 1078 and Otitis Media with Effusion
| Article | Year |
|---|---|
Experimental otitis media with effusion induced by leukotriene D4.
Topics: Animals; Chromones; Cytokines; Humans; Leukotriene Antagonists; Leukotriene D4; Male; Models, Animal | 2002 |