ono 1078 has been researched along with Necrosis in 2 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Necrosis was the main death mode, and the necrotic rate increased 32% after exposure to 220 μM H2O2 for 4 hours." | 1.37 | Pranlukast attenuates hydrogen peroxide-induced necrosis in endothelial cells by inhibiting oxygen reactive species-mediated collapse of mitochondrial membrane potential. ( Fang, SH; Huang, XQ; Lin, KN; Lu, YB; Wei, EQ; Zhang, WP; Zhao, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, SH | 2 |
| Yuan, YM | 1 |
| Peng, F | 1 |
| Li, CT | 1 |
| Zhang, LH | 1 |
| Lu, YB | 2 |
| Zhang, WP | 2 |
| Wei, EQ | 2 |
| Zhao, R | 1 |
| Lin, KN | 1 |
| Huang, XQ | 1 |
2 other studies available for ono 1078 and Necrosis
| Article | Year |
|---|---|
Pranlukast attenuates ischemia-like injury in endothelial cells via inhibiting reactive oxygen species production and nuclear factor-kappaB activation.
Topics: Arachidonate 5-Lipoxygenase; Cell Line; Cell Nucleus; Cell Survival; Chromones; Endothelial Cells; G | 2009 |
Pranlukast attenuates hydrogen peroxide-induced necrosis in endothelial cells by inhibiting oxygen reactive species-mediated collapse of mitochondrial membrane potential.
Topics: Cell Line; Cell Survival; Chromones; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Hy | 2011 |