ono 1078 has been researched along with Muscle Contraction in 13 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 10 (76.92) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakai, H | 2 |
| Konno, M | 2 |
| Kosuge, S | 2 |
| Sakuyama, S | 1 |
| Toda, M | 2 |
| Arai, Y | 2 |
| Obata, T | 2 |
| Katsube, N | 2 |
| Miyamoto, T | 3 |
| Okegawa, T | 2 |
| Zwaagstra, ME | 1 |
| Timmerman, H | 1 |
| Tamura, M | 1 |
| Tohma, T | 1 |
| Wada, Y | 1 |
| Onogi, K | 1 |
| Zhang, MQ | 1 |
| Capra, V | 1 |
| Bolla, M | 1 |
| Belloni, PA | 1 |
| Mezzetti, M | 1 |
| Folco, GC | 1 |
| Nicosia, S | 1 |
| Rovati, GE | 1 |
| Ishimura, M | 1 |
| Kataoka, S | 1 |
| Suda, M | 1 |
| Maeda, T | 1 |
| Hiyama, Y | 1 |
| Fujiwara, H | 1 |
| Kurihara, N | 1 |
| Hirata, K | 1 |
| Matsushita, H | 1 |
| Kanazawa, H | 1 |
| Takeda, T | 1 |
| Tominaga, M | 1 |
| Tsukada, H | 1 |
| Hosokawa, M | 1 |
| Nakamura, H | 1 |
| Taniguchi, T | 1 |
| Ueda, S | 1 |
| Sakai, M | 1 |
| Okuma, M | 1 |
| Panettieri, RA | 1 |
| Tan, EM | 1 |
| Ciocca, V | 1 |
| Luttmann, MA | 1 |
| Leonard, TB | 1 |
| Hay, DW | 1 |
| Wei, EQ | 1 |
| Liu, JW | 1 |
| Zhang, LF | 1 |
| Zhang, WP | 1 |
| Bian, RL | 1 |
| Yodonawa, S | 1 |
| Tsukagoshi, H | 1 |
| Aoki, S | 1 |
| Kurosawa, M | 1 |
| Ishii, A | 1 |
| Nakagawa, T | 1 |
| Nambu, F | 1 |
| Motoishi, M | 1 |
| Okazawa, A | 1 |
| Kobayashi, H | 1 |
| Adachi, M | 1 |
| Takahashi, T | 1 |
| Misawa, M | 1 |
| Yamaguchi, T | 1 |
| Kohrogi, H | 1 |
| Honda, I | 1 |
| Sugimoto, M | 1 |
| Ando, M | 1 |
| Araki, S | 1 |
| Kawasaki, A | 1 |
13 other studies available for ono 1078 and Muscle Contraction
| Article | Year |
|---|---|
New potent antagonists of leukotrienes C4 and D4. 1. Synthesis and structure-activity relationships.
Topics: Animals; Bronchodilator Agents; Cinnamates; Guinea Pigs; Ileum; In Vitro Techniques; Magnetic Resona | 1988 |
Synthesis and structure-activity relationships of carboxylated chalcones: a novel series of CysLT1 (LTD4) receptor antagonists.
Topics: Animals; Chalcone; Guinea Pigs; Ileum; In Vitro Techniques; Leukotriene Antagonists; Lung; Magnetic | 1997 |
Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro.
Topics: Antigens; Benzopyrans; Binding, Competitive; Bronchi; Humans; In Vitro Techniques; Leukotriene D4; L | 1998 |
Effects of KP-496, a novel dual antagonist for leukotriene D4 and thromboxane A2 receptors, on contractions induced by various agonists in the guinea pig trachea.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetates; Acetylcholine; Albuter | 2006 |
Effect of a new leukotriene receptor antagonist, ONO-1078, on human bronchial smooth muscle in vitro.
Topics: Aged; Allergens; Animals; Bronchi; Bronchoconstriction; Chromones; Female; Humans; In Vitro Techniqu | 1993 |
ONO-1078 antagonizes diarrhea-causing changes in ion transport and smooth muscle contraction induced by peptidoleukotrienes in rat and human colon in vitro.
Topics: Adult; Animals; Biological Transport; Chromones; Colon; Diarrhea; Electric Conductivity; Humans; In | 1996 |
Effects of LTD4 on human airway smooth muscle cell proliferation, matrix expression, and contraction In vitro: differential sensitivity to cysteinyl leukotriene receptor antagonists.
Topics: Asthma; Carbachol; Cells, Cultured; Chromones; Dicarboxylic Acids; DNA Replication; Epidermal Growth | 1998 |
Effect of ONO-1078, a leukotriene antagonist, on capsaicin- and substance P-induced bronchoconstriction and airway microvascular leakage in guinea pigs.
Topics: Animals; Bronchi; Bronchoconstriction; Capsaicin; Chromones; Female; Guinea Pigs; In Vitro Technique | 1996 |
[Bronchial hyperresponsiveness to histamine induced by intravenous administration of leukotriene C4 (LTC4) and LTD4 in guinea pigs].
Topics: Airway Resistance; Animals; Asthma; Bronchi; Bronchial Hyperreactivity; Chromones; Guinea Pigs; Hist | 1992 |
Inhibition of endogenous leukotriene-mediated lung anaphylaxis in guinea pigs by a novel receptor antagonist ONO-1078.
Topics: Anaphylaxis; Animals; Asthma; Bronchoconstriction; Chromones; Guinea Pigs; Lung; Male; Muscle Contra | 1990 |
[The effect of leukotriene C4/D4 receptor antagonist (ONO-1078) and thromboxane A2 synthetase inhibitor (OKY-046) on airway hyperresponsiveness induced by ozone exposure in guinea pigs].
Topics: Acrylates; Administration, Inhalation; Animals; Bronchi; Bronchoalveolar Lavage Fluid; Chromones; Gu | 1990 |
[Preventive effect of a novel leukotrienes antagonist ONO-1078 on leukotriene C4- and D4-induced human bronchial smooth muscle contraction].
Topics: Bronchi; Chromones; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; SRS-A | 1990 |
New antagonists of leukotrienes: ONO-RS-411 and ONO-RS-347.
Topics: Anaphylaxis; Animals; Capillary Permeability; Chromones; Dioxanes; Dioxins; Guinea Pigs; Ileum; Musc | 1985 |