ono 1078 has been researched along with Inflammation in 10 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Conventional treatment for acute otitis media mainly targets bacteria with antibiotics, neglecting to control for mediators of inflammation." | 2.82 | The effect of the leukotriene antagonist pranlukast on pediatric acute otitis media. ( Esaki, S; Hamajima, Y; Miyamoto, N; Murakami, S; Nakamura, Y; Nakayama, M; Oshika, M; Sugiyama, K; Suzuki, M; Takagi, I; Yasui, K; Yokota, M, 2016) |
| "Pranlukast attenuates the progression of pulmonary fibrosis in the chronic phase but has no effect on the acute inflammatory response or on the onset of pulmonary fibrosis." | 1.38 | Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice. ( Okunishi, H; Shimbori, C; Shiota, N, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Proschak, E | 1 |
| Heitel, P | 1 |
| Kalinowsky, L | 1 |
| Merk, D | 1 |
| Nakamura, Y | 1 |
| Hamajima, Y | 1 |
| Suzuki, M | 1 |
| Esaki, S | 1 |
| Yokota, M | 1 |
| Oshika, M | 1 |
| Takagi, I | 1 |
| Yasui, K | 1 |
| Miyamoto, N | 1 |
| Sugiyama, K | 1 |
| Nakayama, M | 1 |
| Murakami, S | 1 |
| Tomari, S | 2 |
| Matsuse, H | 2 |
| Hirose, H | 1 |
| Tsuchida, T | 1 |
| Fukahori, S | 1 |
| Fukushima, C | 2 |
| Kawano, T | 2 |
| Matsuo, N | 1 |
| Kohno, S | 2 |
| Shimbori, C | 1 |
| Shiota, N | 1 |
| Okunishi, H | 1 |
| Feldweg, AM | 1 |
| Friend, DS | 1 |
| Zhou, JS | 1 |
| Kanaoka, Y | 1 |
| Daheshia, M | 1 |
| Li, L | 1 |
| Austen, KF | 1 |
| Katz, HR | 1 |
| Okunishi, K | 1 |
| Dohi, M | 1 |
| Nakagome, K | 1 |
| Tanaka, R | 1 |
| Yamamoto, K | 1 |
| Kondo, Y | 1 |
| Machida, I | 1 |
| Saeki, S | 1 |
| Obase, Y | 1 |
| Mizuta, Y | 1 |
| Drazen, JM | 1 |
| Yamauchi, K | 1 |
| Tanifuji, Y | 1 |
| Pan, LH | 1 |
| Yoshida, T | 1 |
| Sakurai, S | 1 |
| Goto, S | 1 |
| Kuroda, S | 1 |
| Kobayashi, H | 1 |
| Inoue, H | 1 |
| Hikasa, Y | 1 |
| Nishikawa, M | 1 |
| Hori, K | 1 |
| Furukawa, K | 1 |
| Yamada, K | 1 |
| Tanida, N | 1 |
| Shimoyama, T | 1 |
2 reviews available for ono 1078 and Inflammation
| Article | Year |
|---|---|
Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery.
Topics: Animals; Cyclooxygenase Inhibitors; Drug Discovery; Fatty Acids; Humans; Inflammation; Models, Molec | 2017 |
New directions in asthma drug therapy.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Chromones; Humans; Hydroxyur | 1998 |
3 trials available for ono 1078 and Inflammation
| Article | Year |
|---|---|
The effect of the leukotriene antagonist pranlukast on pediatric acute otitis media.
Topics: Acute Disease; Anti-Bacterial Agents; Child; Child, Preschool; Chromones; Disease Progression; Drug | 2016 |
Observational study of the additive effects of pranlukast on inflammatory markers of clinically stable asthma with inhaled corticosteroids and long-acting beta 2 agonists.
Topics: Administration, Inhalation; Adrenal Cortex Hormones; Adrenergic beta-Agonists; Adult; Anti-Asthmatic | 2008 |
Effects of pranlukast, a leukotriene receptor antagonist, on airway inflammation in mild asthmatics.
Topics: Adult; Asthma; Chromones; Eosinophils; Female; Humans; Inflammation; Leukocyte Count; Leukotriene An | 2001 |
5 other studies available for ono 1078 and Inflammation
| Article | Year |
|---|---|
Pranlukast, a cysteinyl leukotriene type 1 receptor antagonist, attenuates the progression but not the onset of silica-induced pulmonary fibrosis in mice.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chromones; Cytokines; Disease Progression; Female; Hydroxypro | 2012 |
gp49B1 suppresses stem cell factor-induced mast cell activation-secretion and attendant inflammation in vivo.
Topics: Animals; Cell Degranulation; Chromones; Edema; Female; Inflammation; Male; Mast Cells; Membrane Glyc | 2003 |
A novel role of cysteinyl leukotrienes to promote dendritic cell activation in the antigen-induced immune responses in the lung.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arachidonate 5-L | 2004 |
Effects of anti-inflammatory therapies on recurrent and low-grade respiratory syncytial virus infections in a murine model of asthma.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antigens, Dermatophagoides; Asthma; Bronchoalveola | 2006 |
Leukotriene C4 D4 antagonist markedly reduced inflammation in a rat model of inflammatory bowel disease.
Topics: Animals; Chromones; Colon; Inflammation; Inflammatory Bowel Diseases; Methacrylates; Phenylpropionat | 1992 |