ono 1078 has been researched along with Eosinophilia in 10 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The contributions of histamine, cysteinyl leukotrienes (CysLTs) and thromboxane A2 (TXA2) to the asthmatic responses and the magnitudes of blood and lung eosinophilia at acute and chronic stages of our asthmatic model were comparatively determined." | 3.70 | Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs. ( Kohno, S; Nabe, T; Tomioka, H; Yamashita, K, 1999) |
| "Allergic airway eosinophilia is suppressed by cysteinyl leukotriene (CysLT) receptor (CysLT1 receptor) antagonists in several species including humans and guinea-pigs, suggesting that CysLTs are directly or indirectly involved in induction of the response." | 1.31 | Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs. ( Kawai, T; Kohno, S; Miura, M; Nabe, T; Yamashita, K, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Watanabe, S | 1 |
| Aizawa-Yashiro, T | 1 |
| Tsuruga, K | 1 |
| Takahashi, T | 1 |
| Ito, E | 1 |
| Tanaka, H | 1 |
| Fujimoto, K | 1 |
| Yamaguchi, S | 1 |
| Urushibata, K | 1 |
| Koizumi, T | 1 |
| Kubo, K | 1 |
| Choi, IS | 1 |
| Koh, YI | 1 |
| Joo, JY | 1 |
| Lee, SH | 1 |
| Bae, WG | 1 |
| Ueda, T | 1 |
| Takeno, S | 1 |
| Furukido, K | 1 |
| Hirakawa, K | 1 |
| Yajin, K | 1 |
| Rosenwasser, LJ | 1 |
| Hisada, T | 1 |
| Salmon, M | 1 |
| Nasuhara, Y | 1 |
| Chung, KF | 1 |
| Yamashita, K | 2 |
| Nabe, T | 2 |
| Tomioka, H | 1 |
| Kohno, S | 2 |
| Hojo, M | 1 |
| Suzuki, M | 1 |
| Maghni, K | 1 |
| Hamid, Q | 1 |
| Powell, WS | 1 |
| Martin, JG | 1 |
| Hayashi, S | 1 |
| Furuya, S | 1 |
| Imamura, H | 1 |
| Miura, M | 1 |
| Kawai, T | 1 |
10 other studies available for ono 1078 and Eosinophilia
| Article | Year |
|---|---|
Successful multidrug treatment of a pediatric patient with severe Churg-Strauss syndrome refractory to prednisolone.
Topics: Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Child; Chromones; Churg-Strauss Syndrome; C | 2011 |
Sputum eosinophilia and bronchial responsiveness in patients with chronic non-productive cough responsive to anti-asthma therapy.
Topics: Adult; Aged; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchodilator Agents; | 2003 |
Churg-Strauss syndrome may be induced by leukotriene modifiers in severe asthma.
Topics: Adrenal Cortex Hormones; Adult; Asthma; Chromones; Churg-Strauss Syndrome; Eosinophilia; Humans; Leu | 2003 |
Leukotriene receptor antagonist pranlukast suppresses eosinophil infiltration and cytokine production in human nasal mucosa of perennial allergic rhinitis.
Topics: Adult; Case-Control Studies; Chromones; Cytokines; Enzyme-Linked Immunosorbent Assay; Eosinophilia; | 2003 |
Leukotriene modifiers: new drugs, old and new reactions.
Topics: Acetates; Anti-Asthmatic Agents; Asthma; Autoimmune Diseases; Chromones; Churg-Strauss Syndrome; Cyc | 1999 |
Cysteinyl-leukotrienes partly mediate eotaxin-induced bronchial hyperresponsiveness and eosinophilia in IL-5 transgenic mice.
Topics: Acetylcholine; Airway Resistance; Animals; Benzofurans; Bronchial Hyperreactivity; Bronchial Provoca | 1999 |
Repeated antigen inhalations alter chemical mediators that cause asthmatic obstruction in guinea pigs.
Topics: Administration, Inhalation; Airway Obstruction; Aluminum Hydroxide; Animals; Antigens; Asthma; Benzo | 1999 |
Role of cysteinyl leukotrienes in CD4(+) T cell-driven late allergic airway responses.
Topics: Adoptive Transfer; Airway Resistance; Allergens; Animals; Anti-Allergic Agents; Blood Proteins; Bron | 2000 |
Fulminant eosinophilic endomyocarditis in an asthmatic patient treated with pranlukast after corticosteroid withdrawal.
Topics: Adult; Anti-Asthmatic Agents; Asthma; Biopsy; Chromones; Eosinophilia; Female; Humans; Myocarditis; | 2001 |
Cysteinyl leukotriene-dependent interleukin-5 production leading to eosinophilia during late asthmatic response in guinea-pigs.
Topics: Animals; Asthma; Cell Survival; Chromones; Cysteine; Eosinophilia; Guinea Pigs; Interleukin-5; Kinet | 2002 |