ono 1078 has been researched along with Disease Models, Animal in 25 studies
pranlukast: SRS-A antagonist; leukotriene D4 receptor antagonist
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The drug at this dosage was superior to both comparators in improving mean attack scores and morning and/or evening peak expiratory flow rates, and decreasing the use of rescue bronchodilators (p < 0." | 2.42 | Pranlukast: a review of its use in the management of asthma. ( Goa, KL; Keam, SJ; Lyseng-Williamson, KA, 2003) |
| "Oral montelukast (0." | 1.37 | Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats. ( Fang, SH; Shi, WZ; Wei, EQ; Zhang, YM; Zhao, R, 2011) |
| "However, indomethacin-induced nasal blockage was not provoked in non-sensitized animals." | 1.34 | Nasal blockage induced by oral administration of non-steroidal anti-inflammatory drugs in a guinea-pig model of allergic rhinitis. ( Fujii, M; Han, HY; Kohno, S; Mizutani, N; Nabe, T; Takenaka, H; Terada, T, 2007) |
| "Transient global cerebral ischemia was induced by four-vessel occlusion for 10 min and followed by 72-h reperfusion." | 1.32 | Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on transient global cerebral ischemia in rats. ( Wei, EQ; Zhang, LH, 2003) |
| "Biphasic nasal blockage and sneezing after the challenge in Group A-2 were more severe than those in Group A-0, while those of Group B-7 were almost the same as those of Group B-0." | 1.32 | Acquired nasal hyperresponsiveness aggravates antigen-induced rhinitis in the guinea pig. ( Kohno, S; Mizutani, N; Nabe, T; Takenaka, H, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (36.00) | 18.2507 |
| 2000's | 9 (36.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Hur, J | 1 |
| Kang, JY | 1 |
| Rhee, CK | 1 |
| Kim, YK | 1 |
| Lee, SY | 1 |
| Tang, SS | 1 |
| Ji, MJ | 1 |
| Chen, L | 1 |
| Hu, M | 1 |
| Long, Y | 1 |
| Li, YQ | 1 |
| Miao, MX | 1 |
| Li, JC | 1 |
| Li, N | 1 |
| Ji, H | 1 |
| Chen, XJ | 1 |
| Hong, H | 1 |
| Shi, QJ | 1 |
| Wang, H | 1 |
| Liu, ZX | 1 |
| Fang, SH | 3 |
| Song, XM | 1 |
| Lu, YB | 1 |
| Zhang, WP | 2 |
| Sa, XY | 1 |
| Ying, HZ | 1 |
| Wei, EQ | 4 |
| Okubo, M | 1 |
| Yamanaka, H | 1 |
| Kobayashi, K | 1 |
| Noguchi, K | 1 |
| Mizutani, N | 4 |
| Inui, S | 1 |
| Yoshino, S | 1 |
| Nabe, T | 4 |
| Zhao, R | 1 |
| Shi, WZ | 1 |
| Zhang, YM | 1 |
| Keam, SJ | 1 |
| Lyseng-Williamson, KA | 1 |
| Goa, KL | 1 |
| Zhang, LH | 1 |
| Takenaka, H | 2 |
| Kohno, S | 3 |
| Yamauchi, K | 1 |
| Shinjo, Y | 1 |
| Niwa, T | 1 |
| Imoto, K | 1 |
| Koda, A | 1 |
| Zhou, Y | 1 |
| Wang, ML | 1 |
| Yu, GL | 1 |
| Chu, LS | 1 |
| Chen, Z | 1 |
| She, WY | 1 |
| Dong, Z | 1 |
| Han, HY | 1 |
| Fujii, M | 1 |
| Terada, T | 1 |
| Nishikawa, M | 1 |
| Hikasa, Y | 1 |
| Hori, K | 1 |
| Tanida, N | 1 |
| Shimoyama, T | 1 |
| Taniguchi, H | 1 |
| Takayama, Y | 1 |
| Iwasaka, T | 1 |
| Tamura, T | 1 |
| Takashima, H | 1 |
| Kitashiro, S | 1 |
| Matsui, Y | 1 |
| Sugiura, T | 1 |
| Inada, M | 1 |
| Abraham, WM | 1 |
| Ahmed, A | 1 |
| Cortes, A | 1 |
| Sielczak, M | 1 |
| Hallmon, J | 1 |
| Misawa, M | 1 |
| Sugiyama, Y | 1 |
| Nakagawa, N | 1 |
| Obata, T | 1 |
| Kobayashi, T | 1 |
| Okada, Y | 1 |
| Nambu, F | 1 |
| Terawaki, T | 1 |
| Furuya, T | 1 |
| Muryobayashi, K | 1 |
| Sawada, M | 1 |
| Aishita, H | 1 |
| Narita, S | 2 |
| Asakura, K | 2 |
| Shirasaki, H | 2 |
| Kataura, A | 2 |
| Fujita, M | 1 |
| Yonetomi, Y | 1 |
| Shimouchi, K | 1 |
| Takeda, H | 1 |
| Aze, Y | 1 |
| Kawabata, K | 1 |
| Ohno, H | 1 |
| Arakida, Y | 1 |
| Ohga, K | 1 |
| Suwa, K | 1 |
| Yokota, M | 1 |
| Miyata, K | 1 |
| Yamada, T | 1 |
| Honda, K | 1 |
| Terui, T | 1 |
| Sano, K | 1 |
| Okada, M | 1 |
| Shirota, H | 1 |
| Honda, M | 1 |
| Ozawa, M | 1 |
| Hirasawa, N | 1 |
| Tamura, G | 1 |
| Tagami, H | 1 |
2 reviews available for ono 1078 and Disease Models, Animal
| Article | Year |
|---|---|
[Studies on the experimental allergic rhinitis induced by Japanese cedar pollen--role of cysteinyl leukotrienes in nasal allergic symptoms].
Topics: Allergens; Animals; Bronchial Provocation Tests; Chromones; Cryptomeria; Disease Models, Animal; Gui | 2003 |
Pranlukast: a review of its use in the management of asthma.
Topics: Adolescent; Adult; Aged; Animals; Anti-Asthmatic Agents; Asthma; Child; Chromones; Disease Models, A | 2003 |
23 other studies available for ono 1078 and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
The leukotriene receptor antagonist pranlukast attenuates airway remodeling by suppressing TGF-β signaling.
Topics: Airway Remodeling; Animals; Asthma; Cell Line; Chromones; Collagen; Disease Models, Animal; Female; | 2018 |
Protective effect of pranlukast on Aβ₁₋₄₂-induced cognitive deficits associated with downregulation of cysteinyl leukotriene receptor 1.
Topics: Amyloid beta-Peptides; Animals; Behavior, Animal; CA1 Region, Hippocampal; Chromones; Cognition Diso | 2014 |
HAMI 3379, a CysLT2R antagonist, dose- and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats.
Topics: Acute Disease; Animals; Brain; Brain Edema; Brain Ischemia; Chromones; Cyclohexanecarboxylic Acids; | 2015 |
Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain.
Topics: Animals; Arachidonate 5-Lipoxygenase; Benzoquinones; Chromones; Disease Models, Animal; Enzyme Inhib | 2010 |
Intratracheal sensitization/challenge-induced biphasic asthmatic response and airway hyperresponsiveness in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Asthmatic Agents; Antigens; Asthma; Bronchial Hyperreactivity; Chro | 2010 |
Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats.
Topics: Acetates; Administration, Oral; Animals; Antipyrine; Atrophy; Behavior, Animal; Brain Injury, Chroni | 2011 |
Neuroprotective effect of ONO-1078, a leukotriene receptor antagonist, on transient global cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Chromones; Disease Models, Animal; Hippocampus; Ischemic A | 2003 |
Acquired nasal hyperresponsiveness aggravates antigen-induced rhinitis in the guinea pig.
Topics: Animals; Antigens; Chromones; Disease Models, Animal; Guinea Pigs; Histamine H1 Antagonists; Leukotr | 2003 |
Delayed-type asthmatic response induced by repeated intratracheal exposure to toluene-2,4-diisocyanate in guinea pigs.
Topics: Airway Resistance; Albumins; Albuterol; Allergens; Animals; Asthma; Chromones; Dexamethasone; Diseas | 2005 |
Increased expression of cysteinyl leukotriene receptor-1 in the brain mediates neuronal damage and astrogliosis after focal cerebral ischemia in rats.
Topics: Animals; Astrocytes; Brain Ischemia; Cerebral Infarction; Chromones; Disease Models, Animal; Encepha | 2006 |
[Effect of Pranlukast on tissue remodeling in experimental guinea pig allergic rhinitis model].
Topics: Animals; Chromones; Disease Models, Animal; Epithelial Cells; Guinea Pigs; Male; Nasal Mucosa; Rhini | 2006 |
Nasal blockage induced by oral administration of non-steroidal anti-inflammatory drugs in a guinea-pig model of allergic rhinitis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Diclofen | 2007 |
Effect of leukotriene C4D4 antagonist on colonic damage induced by intracolonic administration of trinitrobenzene sulfonic acid in rats.
Topics: Animals; Chromones; Colon; Disease Models, Animal; Eicosanoids; Female; Inflammatory Bowel Diseases; | 1995 |
Effect of the leukotriene receptor antagonist ONO-1078 on extravascular lung water after coronary ligation in dogs.
Topics: Animals; Chromones; Disease Models, Animal; Dogs; Female; Hemodynamics; Male; Myocardial Infarction; | 1993 |
The effects of a cysteinyl leukotriene antagonist (ONO-1078) on antigen-induced responses in allergic sheep.
Topics: Airway Resistance; Animals; Antigens, Helminth; Ascaris; Bronchoalveolar Lavage Fluid; Bronchoconstr | 1993 |
An airway hyperresponsiveness model in rat allergic asthma.
Topics: Acetylcholine; Animals; Ascaris; Asthma; Bronchial Hyperreactivity; Capillary Permeability; Chromone | 1993 |
Effect of a peptide leukotriene receptor antagonist, ONO-1078, on guinea-pig models of asthma.
Topics: Acetylcholine; Acute-Phase Reaction; Animals; Asthma; Bronchoalveolar Lavage Fluid; Bronchoconstrict | 1993 |
Effects of a cysteinyl leukotriene antagonist, ONO-1078 (pranlukast), on total airway resistance after antigen challenge in sensitized guinea pigs.
Topics: Administration, Topical; Airway Resistance; Animals; Anti-Asthmatic Agents; Chromones; Cysteine; Dis | 1997 |
The effect of a cysteinyl leukotriene antagonist, ONO-1078 (pranlukast) on agonist- and antigen-induced nasal microvascular leakage in guinea pigs.
Topics: Animals; Anti-Asthmatic Agents; Chromones; Disease Models, Animal; Guinea Pigs; Leukotriene Antagoni | 1998 |
Involvement of cysteinyl leukotrienes in biphasic increase of nasal airway resistance of antigen-induced rhinitis in guinea pigs.
Topics: Airway Resistance; Animals; Chromones; Cysteine; Disease Models, Animal; Guinea Pigs; Leukotriene An | 1999 |
Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs.
Topics: Administration, Oral; Animals; Asthma; Chromones; Disease Models, Animal; Guinea Pigs; Immunization, | 1999 |
Production and pharmacologic modulation of the granulocyte-associated allergic responses to ovalbumin in murine skin models induced by injecting ovalbumin-specific Th1 or Th2 cells.
Topics: Animals; Cells, Cultured; Chromones; Dermatitis, Atopic; Disease Models, Animal; Ear; Edema; Enzyme | 2001 |